Structural insights into Plasmodium falciparum nicotinamide mononucleotide adenylyltransferase: oligomeric assembly.

abstract：:Qualitative bacteriological analysis was carried out in two sewage treatment plants in the city of Rio de Janeiro during the period 1984-1985. Specific points of the plants were selected for the collection of affluent and effluent samples. The study involved the isolation and the identification of 540 cultures of Esch...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ribeiro Dias JC,Vicente AC,Hofer E

更新日期：1987-07-01 00:00:00

abstract：:In this study we compared two polymerase chain reaction (PCR) methods using either 16S ribosomal RNA (rRNA) or 23S rRNA gene primers for the detection of different Leptospira interrogans serovars. The performance of these two methods was assessed using DNA extracted from bovine tissues previously inoculated with sever...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： D'Andrea A,Martinez YZ,Alduina R,Monteverde V,Molina CF,Vitale M

更新日期：2012-02-01 00:00:00

abstract：:In Brazil, carbapenem-resistant Pseudomonas aeruginosa isolates are closely related to the São Paulo metallo-β-lactamase (SPM) Brazilian clone. In this study, imipenem-resistant isolates were divided in two sets, 2002/2003 and 2008/2009, analysed by pulsed field gel electrophoresis and tested for the Ambler class B me...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cavalcanti FL,Almeida AC,Vilela MA,Morais MM,Morais Junior MA

更新日期：2012-05-01 00:00:00

abstract：:Four diamines and three amino alcohols derived from 1-decanol, 1-dodecanol and 1,2-dodecanediol were evaluated in an in vitro assay against a mixture of trypomastigote and intracellular amastigote forms of Trypanosoma cruzi. Two of these compounds (6 and 7) showed better activity against both proliferative stages of T...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sales Júnior PA,Rezende Júnior CO,Le Hyaric M,Almeida MV,Romanha AJ

更新日期：2014-06-01 00:00:00

abstract：:Mitochondrial DNA of Biomphalaria tenagophila, a mollusc intermediate host of Schistosoma mansoni in Brazil, was sequenced and characterised. The genome size found for B. tenagophila was 13,722 bp and contained 13 messenger RNAs, 22 transfer RNAs (tRNA) and two ribosomal RNAs (rRNA). In addition to sequencing, the mit...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Jannotti-Passos LK,Ruiz JC,Caldeira RL,Murta SM,Coelho PM,Carvalho OS

更新日期：2010-07-01 00:00:00

abstract：:BACKGROUND The main strategy to control human malaria still relies on specific drug treatment, limited now by Plasmodium falciparum-resistant parasites, including that against artemisinin derivatives. Despite the large number of active compounds described in the literature, few of them reached full development against...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Penna-Coutinho J,Aguiar AC,Krettli\/ AU

更新日期：2018-12-06 00:00:00

abstract：:Coprolite samples of human and animal origin from the excavations performed at the archaeological site of Furna do Estrago, at Brejo da Madre de Deus in the state of Pernambuco, Brazil and sent to the Paleoparasitology Laboratory at Escola Nacional de Saúde Pública-Fiocruz, Rio de Janeiro, were analyzed for mites. Aft...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Candanedo Guerra Rde M,Gazêta GS,Amorim M,Duarte AN,Serra-Freire NM

更新日期：2003-01-01 00:00:00

abstract：:The authors investigated the distribution of lectin receptors on Trypanosoma cruzi blood forms collected from mice inoculated with, respectively, the drug-resistant and drug-sensitive strains VL-10 and CL, and treated with the two standard active nitroheterocyclic compounds nifurtimox and benznidazole used for treatme...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Fontes G,Romanha AJ,Pereira ME,Brener Z

更新日期：1991-07-01 00:00:00

abstract：:Anopheles (Nyssorhynchus) pristinus Nagaki & Sallum, n. sp. of the Myzorhynchella Section is described based on morphological characters of adult females, males, fourth-instar larvae, pupae and male genitalia. Anopheles (Nyssorhynchus) antunesi Galvão & Amaral is characterized to fix its identity and distinguish it fr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nagaki SS,Motta Mde A,Sallum MA

更新日期：2010-05-01 00:00:00

abstract：:In the present paper, we developed a primary culture of Rhodnius prolixus salivary gland and main salivary canal cells. Cells remained viable in culture for 30 days. Three types of cells were indentified in the salivary gland cultures, with binuclear cells being the most abundant. The supernatants of salivary cultures...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Rocha FF,Araujo RN,Silva LM,Gontijo NF,Pereira MH

更新日期：2010-03-01 00:00:00

abstract：:In this study we investigated the larval dispersal associated with larval predation in experimental populations of Chrysomya albiceps and Cochliomyia macellaria. Frequency distribution of sampling units (G test) in the substrate was used to evaluate variation in larval dispersal. An experimental acrylic channel (1 x 0...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Andrade JB,Rocha FA,Rodrigues P,Rosa GS,Faria Ldel B,Von Zuben CJ,Rossi MN,Godoy WA

更新日期：2002-12-01 00:00:00

abstract：:Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric oxide (NO) production. We previously demonstrated the correlation between serum levels of NO and the severity of renal disease in patients with severe leptospir...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Santos CS,Azevedo EC,Soares LM,Carvalho MO,dos Santos AC,das Chagas AD Jr,da Silva CL,Chagas UM,dos Reis MG,Athanazio DA

更新日期：2013-06-01 00:00:00

abstract：:The dual function of eosinophils has been evidenced in protective immunity against parasites as well as in pathological manifestations during allergic disorders. We have demonstrated that a new class of IgE receptors, Fc epsilon RII/CD23, was involved in the functional duality of eosinophils and other proinflammatory ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nutten S,Trottein F,Gounni AS,Papin JP,Capron A,Capron M

更新日期：1997-01-01 00:00:00

abstract：:The trypanosomatid cytoskeleton is responsible for the parasite's shape and it is modulated throughout the different stages of the parasite's life cycle. When parasites are exposed to media with reduced osmolarity, they initially swell, but subsequently undergo compensatory shrinking referred to as regulatory volume d...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dagger F,Valdivieso E,Marcano AK,Ayesta C

更新日期：2013-02-01 00:00:00

abstract：:In Brazil, malaria still remains a clinically important febrile syndrome for local populations and travelers, occurring mostly in the Amazon Basin. This review aims to report the main efforts employed to control this disease since the 1940s and the emergence of Plasmodium falciparum and Plasmodium vivax chemoresistanc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gama BE,Lacerda MV,Daniel-Ribeiro CT,Ferreira-da-Cruz Mde F

更新日期：2011-08-01 00:00:00

abstract：:Discovered in 1909, Chagas disease was progressively shown to be widespread throughout Latin America, affecting millions of rural people with a high impact on morbidity and mortality. With no vaccine or specific treatment available for large-scale public health interventions, the main control strategy relies on preven...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dias JC,Silveira AC,Schofield CJ

更新日期：2002-07-01 00:00:00

abstract：:Two of the major problems facing the Amazon - human migration from the other areas and uncontrolled deforestation - constitute the greatest risk for the establishment of endemic Chagas disease in this part of Brazil. At least 18 species of triatomines had been found in the Brazilian Amazon, 10 of them infected with Tr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Coura JR,Junqueira AC,Boia MN,Fernandes O

更新日期：1999-01-01 00:00:00

abstract：:Nitroarylidenemalononitriles and their cyanoacetamide derivatives with remarkable anti-epimastigote properties, were synthesized attempting to obtain new 3,5-diamino-4-(5'-nitroarylidene)-4H-thiadiazine 1,1-dioxide derivatives, which in previous reports had shown anti-Trypanosoma cruzi activity. Tests to evaluate the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Muelas-Serrano S,Le-Senne A,Fernandez-Portillo C,Nogal JJ,Ochoa C,Gomez-Barrio A

更新日期：2002-06-01 00:00:00

abstract：:This paper examines the distribution and infection of Biomphalaria glabrata with Schistosoma mansoni in all aquatic snail habitats in a rural area in the state of Minas Gerais, Brazil, in relation to physico/biotic and behavioral factors. Snail and environmental surveys were carried out semi-annually between July 2001...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kloos H,Passos LK,Loverde P,Oliveira RC,Gazzinelli A

更新日期：2004-11-01 00:00:00

abstract：:Benznidazole (Bz) exhibits toxic side effects in animal studies and clinical use. Reductive metabolism of Bz in liver microsomes modulates the duration of its chemotherapeutic effect and its toxicity. The rate of this metabolism depends on age and is less intense in newborns and youngsters than in adults. In the prese...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bulffer RF,Castro JA,Fanelli SL

更新日期：2011-05-01 00:00:00

abstract：:This study sought the characterization of rotaviruses in a trial with a tetravalent rhesus-human rotavirus vaccine in Belém, Brazil in children who received three doses of vaccine or placebo in the 1st, 3rd and 5th months of life. Rotavirus electropherotypes, subgroups, G serotypes, G, [P] and [P], G genotypes were de...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mascarenhas JD,Linhares AC,Gabbay YB,Leite JP

更新日期：2002-01-01 00:00:00

abstract：:Faeces from 17 children less than 1.6 years old and 15 adults more than 22 years old were collected during an outbreak of gastroenteritis in a day care nursery and screened for the presence of adenovirus and rotavirus by enzyme immunoassay (EIARA) and other viruses by electron microscopy (EM) and polyacrylamide gel el...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Castro L,Rodrigues Ddos P,Flauzino R,Moura M,Leite JP

更新日期：1994-01-01 00:00:00

abstract：:This study aimed to analyse the spatial distribution of human (2007-2013) and canine (2013) visceral leishmaniasis (VL) in the city of Araçuaí, Minas Gerais, Brazil, and identify the socio-environmental factors related to their occurrence. The spatial distribution of human and canine cases was analysed by kernel densi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ursine RL,Dias JV,Morais HA,Pires HH

更新日期：2016-07-04 00:00:00

abstract：:Toxoplasma gondii has a very wide intermediate host range and is thought to be able to infect all warm blooded animals. The parasite causes a spectrum of different diseases and clinical symptoms within the intermediate hosts and following infection most animals develop adaptive humoral and cell-mediated immune respons...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Innes EA,Bartley PM,Maley S,Katzer F,Buxton D

更新日期：2009-03-01 00:00:00

abstract：:Dipteran polytene chromosomes provide an excellent model for understanding in species complexes, as well as for structural and functional cytogenetics. The status of species in the Culex pipiens complex is controversial and the use of polytene chromosomes for cytogenetic analysis in the subfamily Culicinae has been di...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Campos J,Andrade CF,Recco-Pimentel SM

更新日期：2003-04-01 00:00:00

abstract：:BACKGROUND Human herpesvirus 2 (HHV-2) have DNA genome with a limited genetic variability and have been classified into two clades. OBJECTIVES To identify and characterise six HHV-2 isolates derived from Brazilian women. METHODS HHV-2 isolates were performed polymerase chain reaction (PCR) and sequencing of 2250 pb of...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Lima LRP,Araújo NA,Guterres A,Pilotto JH,Niel C,Paula VS

更新日期：2018-12-03 00:00:00

abstract：:For the first time, a jar of embalming rejects was studied in search for helminth parasite eggs. This kind of jar was used to put discarded material by Egyptian embalmers during mummification process. Ascaris lumbricoides and Taenia saginata eggs were found in the linen and strip fragment contents of the jar, dated of...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Harter S,Le Bailly M,Janot F,Bouchet F

更新日期：2003-01-01 00:00:00

abstract：:Warileya lumbrerasi n. sp. is described from the northern Peruvian Andes. This species was collected inside houses, and is the seventh species described within the genus Warileya Hertig, 1948. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ogusuku E,Perez JE,Davies CR,Villaseca P

更新日期：1996-11-01 00:00:00

abstract：:In order to determine the best type of rabies vaccine to use as a booster, 78 serological samples from singly vaccinated cattle were analyzed by counterimmunoelectrophoresis technique. The animals were divided into several groups, received the first vaccine dose with modified live virus vaccine (ERA strain) and were r...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira AN,Andrade MC,Silva MV,Moura WC,Cortez Contreiras E

更新日期：2000-01-01 00:00:00

abstract：:Phlebotominae includes some vector species, mainly that of leishmaniases, with a very old host-parasite relationship. Some species fossils of this subfamily have been recently described and this paper presents the description of a new sand fly Pintomyia (Pifanomyia) paleotownsendi sp. nov in amber. The gonostyle prese...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Filho JD,Falcão AL,Galati EA,Brazil RP

更新日期：2006-12-05 00:00:00