In vitro and in vivo anti-Trypanosoma cruzi activity of a novel nitro-derivative.

abstract：:The infection pattern in Swiss mice and Triatomine bugs (Rhodnius neglectus) of eleven clones and the original stock of a Trypanosoma cruzi isolate, derived from a naturally infected Didelphis marsupialis, were biochemically and biologically characterized. The clones and the original isolate were in the same zymodeme ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Lima VS,Mangia RH,Carreira JC,Marchevsky RS,Jansen AM

更新日期：1999-05-01 00:00:00

abstract：:The number of visceral leishmaniasis (VL) cases has increased over the past 10 years in Brazil, especially in the North and Northeast regions of the country. The aim of this study was to evaluate the urbanisation of VL vectors in Barcarena, Pará, an area in northern Brazil where VL is endemic. Sandflies were captured ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira DM,Saraiva EM,Ishikawa EA,Sousa AA,Silva EO,Silva IM

更新日期：2011-12-01 00:00:00

abstract：:A polysaccharide-rich fraction (ATF) of medicinal mushroom Agaricus brasiliensis was evaluated on the candidacidal activity, H2O2 and nitric oxide (NO) production, and expression of mannose receptors by murine peritoneal macrophages. Mice received three intraperitoneal (i.p.) injections of ATF and after 48 h their per...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martins PR,Gameiro MC,Castoldi L,Romagnoli GG,Lopes FC,Pinto AV,Loyola W,Kaneno R

更新日期：2008-05-01 00:00:00

abstract：:Morphometrics of Brazilian strains (BH, SJ and CMO) of Schistosoma mansoni cercariae were obtained with a computerized image analyzer (IMAGE PRO PLUS, MEDIA CYBERNETICS), considering the following characters: body area, tail, furcae, oral and ventral suckers and distance between them. For statistical analysis, the var...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Machado-Silva JR,da Silva CH,Pereira MJ,de Oliveira RM,Pinto RM,Gomes DC

更新日期：2000-11-01 00:00:00

abstract：:Several protozoan parasites exist in the Trypanosomatidae family, including various agents of human diseases. Multiple lines of evidence suggest that important differences are present between the translational and mRNA processing (trans splicing) systems of trypanosomatids and other eukaryotes. In this context, certai...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva MT,Ambrósio DL,Trevelin CC,Watanabe TF,Laure HJ,Greene LJ,Rosa JC,Valentini SR,Cicarelli RM

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Biomphalaria glabrata snails are widely distributed in schistosomiasis endemic areas like America and Caribe, displaying high susceptibility to infection by Schistosoma mansoni. After the availability of B. glabrata genome and transcriptome data, studies focusing on genetic markers and small non-coding RNAs ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Queiroz FR,Portilho LG,Jeremias WJ,Babá ÉH,do Amaral LR,Silva LM,Coelho PMZ,Caldeira RL,Gomes MS

更新日期：2020-07-01 00:00:00

abstract：:In Argentina, most information on hepatitis C virus (HCV) genotype distribution comes from studies carried out in Buenos Aires (east province). In order to identify HCV subtypes in central Argentina, nucleotide sequencing of core region was performed in samples from 36 patients living in Córdoba, the second most popul...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ré V,Contigiani M,Yoshida CF,Lampe E

更新日期：2007-12-01 00:00:00

abstract：:Catadiscus pomaceae sp. n. from the intestine of the prosobranch mollusc Pomacea canaliculata (Lamarck, 1801), is described. The host snail was collected from a lenitic biotope belonging to the Riachuelo basin (Corrientes province, Argentina) during 1985-1986. So far the species of the genus Catadiscus Cohn, 1904 have...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Hamann MI

更新日期：1992-01-01 00:00:00

abstract：:Clinical and laboratory evidence is reviewed which shows that there is a great deal of variation in the susceptibility of Schistosoma mansoni to oxamniquine. This variation occurs both among endemic regions and within endemic regions in Brazil and Kenya. It is genetically controlled. It is suggested that the parasite ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kinoti GK

更新日期：1987-01-01 00:00:00

abstract：:In the Americas, hantaviruses cause severe cardiopulmonary syndrome (HCPS) with a high fatality rate. Hantavirus infection is commonly diagnosed using serologic techniques and reverse transcription-polymerase chain reaction. This paper presents a novel plaque reduction neutralisation test (PRNT) for detecting antibodi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pádua Md,Souza WM,Lauretti F,Figueiredo LT

更新日期：2015-08-01 00:00:00

abstract：:Since the 1940s, French Guiana has implemented vector control to contain or eliminate malaria, yellow fever, and, recently, dengue, chikungunya, and Zika. Over time, strategies have evolved depending on the location, efficacy of the methods, development of insecticide resistance, and advances in vector control techniq...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Epelboin Y,Chaney SC,Guidez A,Habchi-Hanriot N,Talaga S,Wang L,Dusfour I

更新日期：2018-03-12 00:00:00

abstract：:Ketoconazole, an azole antifungic drug which is already in the market has also been demonstrated to be active against Trypanosoma cruzi experimental infections. In this paper we confirmed the drug effect and investigated its range of activity against different T. cruzi strains naturally resistant or susceptible to bot...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Brener Z,Cançado JR,Galvão LM,da Luz ZM,Filardi Lde S,Pereira ME,Santos LM,Cançado CB

更新日期：1993-01-01 00:00:00

abstract：:Calomys callosus, Rengger 1830 (Rodentia, Cricetidae), a wild rodent found in Central Brazil, was studied to investigate its susceptibility to Toxoplasma gondii experimental infection and its humoral immune response against this protozoa. The electrophoretic profile of the serum proteins of C. callosus showed that IgG...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Favoreto-Júnior S,Ferro EA,Clemente D,Silva DA,Mineo JR

更新日期：1998-01-01 00:00:00

abstract：:Rhesus monkeys (Macaca mulatta) were infected subcutaneously with 1.0 x 10(4) to 1.5 x 10(4) metacyclic trypomastigotes of Trypanosoma cruzi (Colombian strain). Parasitological and immunological parameters were evaluated in these animals for periods of 1 month to over 3 years. A chagoma was observed between the 3rd an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bonecini-Almeida Mda G,Galvão-Castro B,Pessoa MH,Pirmez C,Laranja F

更新日期：1990-04-01 00:00:00

abstract：:Predictions that deforestation would reduce American cutaneous leishmaniasis incidence have proved incorrect. Presentations at a recent international workshop, instead, demonstrated frequent domestication of transmission throughout Latin America. While posing new threats, this process also increases the effectiveness ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Campbell-Lendrum D,Dujardin JP,Martinez E,Feliciangeli MD,Perez JE,Silans LN,Desjeux P

更新日期：2001-02-01 00:00:00

abstract：:Experimental infections by Trypanosoma (Megatrypanum) minasense were performed in primates - Saimiri sciureus and Callithrix penicillata - with the objective of searching for morphological variations of the blood trypomastigotes with respect to hosts and time of infection. We carried out morphological and morphometric...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ziccardi M,Lourenco-de-Oliveira R

更新日期：1999-09-01 00:00:00

abstract：:A pseudogene, designated as "ps(5.8S+ITS-2)", paralogous to the 5.8S gene and internal transcribed spacer (ITS)-2 of the nuclear ribosomal DNA (rDNA), has been recently found in many triatomine species distributed throughout North America, Central America and northern South America. Among characteristics used as crite...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Zuriaga MA,Mas-Coma S,Bargues MD

更新日期：2015-05-01 00:00:00

abstract：:This paper presents epidemiological, laboratory, and clinical data on 12 years of dengue virus activity in the State of Rio de Janeiro from the time the disease was first confirmed virologically in April 1986 through April 1998. DEN-1 and DEN-2 viruses are the serotypes circulating in the state and were responsible fo...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nogueira RM,Miagostovich MP,Schatzmayr HG,dos Santos FB,de Araújo ES,de Filippis AM,de Souza RV,Zagne SM,Nicolai C,Baran M,Teixeira Filho G

更新日期：1999-05-01 00:00:00

abstract：:The association between pyogenic liver abscesses and schistosomiasis has been confirmed by clinical and experimental studies. In this retrospective study of 78 patients with pyogenic liver abscesses the association with schistosomiasis has been investigated. Pyodermitis, a known focus of bacteremia, was observed in 19...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teixeira R,Pfeilsticker FJ,Santa Cecília GD,Nobre V,Fonseca LP,Serufo JC,Coelho PM,Lambertucci JR

更新日期：2001-01-01 00:00:00

abstract：:New alternative insecticides are necessary for the chemical control of head lice. In this study the fumigant knockdown time 50% (KT50) and repellency index (RI) of three aliphatic lactones was compared with two essential oils and DDVP, against permethrin-resistance Pediculus humanus capitis from Argentina. In the fumi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Toloza AC,Zygadlo J,Mougabure-Cueto G,Zerba E,Faillaci S,Picollo MI

更新日期：2006-02-01 00:00:00

abstract：:A sylvatic Triatoma infestans DM (dark morph) population detected in the Bolivian Chaco was characterized and compared with various domestic ones. The degree of differentiation of DM was clearly within the T. infestans intra-specific level. Nevertheless marked chromatic and morphometric differences as well as differen...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Noireau F,Bastrenta B,Catalá S,Dujardin JP,Panzera F,Torres M,Perez R,Galvão C,Jurberg J

更新日期：2000-01-01 00:00:00

abstract：:The ecology of phlebotomine sandflies in an endemic focus of cutaneous leishmaniasis in Northern Venezuela (San Esteban, Carabobo State) was investigated through a year-term study. Three different habitats: viz. a house, a peridomestic area and a sylvatic area, were covered and the species composition, the abundance a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Feliciangeli MD

更新日期：1987-01-01 00:00:00

abstract：:We analyzed prospectively 326 laboratory-confirmed, uncomplicated malarial infections (46.3% due to Plasmodium vivax, 35.3% due to P. falciparum, and 18.4% mixed-species infections) diagnosed in 162 rural Amazonians aged 5-73 years. Thirteen symptoms (fever, chills, sweating, headache, myalgia, arthralgia, abdominal p...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： da Silva-Nunes M,Ferreira MU

更新日期：2007-06-01 00:00:00

abstract：:A survey of the carrion fauna was made at two sites in Curitiba, State of Paraná, with the objective of describing the insects associated with carrion and setting up a preliminary data-base for medico-legal purposes in south Brazil. Vertebrate exclusion experiments were carried out in each season between 1994 and 1995...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Moura MO,de Carvalho CJ,Monteiro-Filho EL

更新日期：1997-03-01 00:00:00

abstract：:Data analysis, presentation and distribution is of utmost importance to a genome project. A public domain software, ACeDB, has been chosen as the common basis for parasite genome databases, and a first release of TcruziDB, the Trypanosoma cruzi genome database, is available by ftp from ftp://iris.dbbm.fiocruz.br/pub/g...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Degrave W,de Miranda AB,Amorim A,Brandão A,Aslett M,Vandeyar M

更新日期：1997-11-01 00:00:00

abstract：:In an endemic area of cutaneous leishmaniasis in Rio de Janeiro State where a mule had been found infected, a systematic search among equines was performed, resulting in the detection of Leishmania parasites in skin lesions of 30.8% of the animals, which included horses and mules. The eventual role of equines in the e...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Aguilar CM,Rangel EF,Deane LM

更新日期：1986-10-01 00:00:00

abstract：:Aspects related to hatching, lifetime, number of blood meals for molting, mortality, feeding time, and postfeeding defecation delay were evaluated and compared in each instar of three North American Triatominae: Triatoma gerstaeckeri, Triatoma lecticularia and Triatoma protracta, all of them fed on rabbits. No signifi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martínez-Ibarra JA,Alejandre-Aguilar R,Paredes-González E,Martínez-Silva MA,Solorio-Cibrián M,Nogueda-Torres B,Trujillo-Contreras F,Novelo-López M

更新日期：2007-12-01 00:00:00

abstract：:The yield as well as phenotypic and functional parameters of canine peripheral blood monocyte-derived macrophages were analyzed. The cells that remained adherent to Teflon after 10 days of culture had high phagocytic activity when inoculated with Leishmania chagasi. Flow cytometric analysis demonstrated that more than...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bueno R,Mello MN,Menezes CA,Dutra WO,Santos RL

更新日期：2005-08-01 00:00:00

abstract：:Epstein-Barr virus (EBV) plays a major role in liver pathology. Similar to other members of the herpesvirus family, EBV establishes a persistent infection in more than 90% of adults. The aim of this study was to evaluate the impact of EBV and chronic hepatitis C co-infection (HCV) on biochemical and immunological resp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Shoman S,Nabil M,Tabl A,Ghanem H,Kafrawy SE

更新日期：2014-09-01 00:00:00

abstract：:The objective of this study was to evaluate the feeding behavior of Triatoma vitticeps through the identification of its food sources and the characterization of the blood ingestion process. In addition, we aimed to verify if the saliva of this vector interferes with the perception of the host during the feedings by c...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Souza Rde C,Soares AC,Alves CL,Lorosa ES,Pereira MH,Diotaiuti L

更新日期：2011-02-01 00:00:00