Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae.

abstract：:Coagulase-negative staphylococci (CNS) have been identified as the etiological agent in various infections and are currently the microorganisms most frequently isolated in nosocomial infections. However, little is known about the virulence factors produced by CNS that contribute to the pathogenesis of infections cause...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cunha Mde L,Rugolo LM,Lopes CA

更新日期：2006-09-01 00:00:00

abstract：:The object of the investigation was the evaluation of the susceptibility to antibiotic and chemotherapeutic agents of 240 strains of Salmonella agona isolated from different sources (human, food and environment) obtained from five Brazilian states (Minas Gerais, São Paulo, Rio de Janeiro, Pernambuco and Rio Grande do ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Solari CA,dos Reis EM,Dias JC,Hofer E

更新日期：1986-01-01 00:00:00

abstract：:This article presents an overview of the currently available drugs nifurtimox (NFX) and benznidazole (BZN) used against Trypanosoma cruzi, the aetiological agent of Chagas disease; herein we discuss their limitations along with potential alternatives with a focus on ergosterol biosynthesis inhibitors (EBI). These comp...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Urbina JA

更新日期：2009-07-01 00:00:00

abstract：:The ultrastructure of endogenous stages of Eimeria ninakohlyakimovae was observed in epithelial cells of cecum and colon crypts from a goat experimentally infected with 2.0 x 10(5) oocysts/kg. The secondary meronts developed above the nucleus of the host cell. The nucleus first divides and merozoites then form on the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vieira LS,Lima JD,Ribeiro MF,Bozzi IA,Camargos ER

更新日期：1997-07-01 00:00:00

abstract：:Aspects related to hatching, lifetime, number of blood meals for molting, mortality, feeding time, and postfeeding defecation delay were evaluated and compared in each instar of three North American Triatominae: Triatoma gerstaeckeri, Triatoma lecticularia and Triatoma protracta, all of them fed on rabbits. No signifi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Martínez-Ibarra JA,Alejandre-Aguilar R,Paredes-González E,Martínez-Silva MA,Solorio-Cibrián M,Nogueda-Torres B,Trujillo-Contreras F,Novelo-López M

更新日期：2007-12-01 00:00:00

abstract：:Anopheles (Nyssorhynchus) pristinus Nagaki & Sallum, n. sp. of the Myzorhynchella Section is described based on morphological characters of adult females, males, fourth-instar larvae, pupae and male genitalia. Anopheles (Nyssorhynchus) antunesi Galvão & Amaral is characterized to fix its identity and distinguish it fr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Nagaki SS,Motta Mde A,Sallum MA

更新日期：2010-05-01 00:00:00

abstract：:The natural lignans veraguensin and grandisin have been reported to be active against Trypanosoma cruzi bloodstream forms. Aiming at the total synthesis of these and related compounds, we prepared three 2-arylfurans and eight 2,5-diarylfurans. They were evaluated for their potential as T. cruzi trypanothione reductase...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Oliveira RB,Vaz AB,Alves RO,Liarte DB,Donnici CL,Romanha AJ,Zani CL

更新日期：2006-03-01 00:00:00

abstract：:A vaccination campaign against pandemic influenza A (H1N1)pdm09 was held in Brazil in March 2010, using two types of monovalent split virus vaccines: an AS03-adjuvanted vaccine and a non-adjuvanted vaccine. We compared the reactogenicity of the vaccines in health professionals from a Clinical Research Institute in Rio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cerbino-Neto J,Santos AT,Gouvea MI,Pedro RS,Ramos GV,Guaraldo L,Werneck GL

更新日期：2012-11-01 00:00:00

abstract：:Ketoconazole, an azole antifungic drug which is already in the market has also been demonstrated to be active against Trypanosoma cruzi experimental infections. In this paper we confirmed the drug effect and investigated its range of activity against different T. cruzi strains naturally resistant or susceptible to bot...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Brener Z,Cançado JR,Galvão LM,da Luz ZM,Filardi Lde S,Pereira ME,Santos LM,Cançado CB

更新日期：1993-01-01 00:00:00

abstract：:Chagas cardiomyopathy is the most frequent and most severe manifestation of chronic Chagas disease, and is one of the leading causes of morbidity and death in Latin America. Although the pathogenesis of Chagas cardiomyopathy is incompletely understood, it may involve several mechanisms, including parasite-dependent my...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Rassi A Jr,Marin JA Neto,Rassi A

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The time of progression towards AIDS can vary greatly among seropositive patients, and may be associated with host genetic variation. The NR1I2 (PXR) gene, a ligand-activated transcription factor, regulates the transcription immune pathway genes and can therefore be targets of viral replication mechanisms in...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Medeiros RM,Menti CF,Benelli JL,Matte MC,Melo MG,Almeida SE,Fiegenbaum M

更新日期：2017-04-01 00:00:00

abstract：:The haemolymph of Panstrongylus megistus showed a natural lectin activity for a wide range of vertebrate erythrocytes. Agglutination was observed against all vertebrate erythrocytes tested (human ABO, duck, rabbit, mouse, sheep, chicken and cow). Cow erythrocytes showed the lowest titre. Concerning human erythrocytes,...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gomes YM,Furtado AF,De Carvalho AB

更新日期：1988-10-01 00:00:00

abstract：:Cells die through a programmed process or accidental death, know as apoptosis or necrosis, respectively. Bothrops jararaca is a snake whose venom inhibits the growth of Trypanosoma cruzi epimastigote forms causing mitochondrion swelling and cell death. The aim of the present work was to determine the type of death ind...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Deolindo P,Teixeira-Ferreira AS,Melo EJ,Arnholdt AC,Souza Wd,Alves EW,DaMatta RA

更新日期：2005-02-01 00:00:00

abstract：:Sand fly identification is complex because it depends on the expertise of the taxonomist. The females show subtle morphological differences and the occurrence of the species complexes are usual in this taxon. Therefore, a fragment of the cytochrome c oxidase subunit I (COI) gene is used for taxon barcoding to resolve ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Laurito M,Ontivero IM,Almirón WR

更新日期：2019-11-28 00:00:00

abstract：:An increasing amount of research has been conducted on immunoglobulin Y (IgY) because the use of IgY offers several advantages with respect to diagnostic testing, including its easy accessibility, low cost and translatability to large-scale production, in addition to the fact that it can be ethically produced. In a pr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bentes GA,Lanzarini NM,Lima LR,Manso PP,da Silva Ados S,Mouta Junior Sda S,Guimarães JR,de Moraes MT,Pelajo-Machado M,Pinto MA

更新日期：2015-06-01 00:00:00

abstract：:This paper evaluates CHCl3 and CH3OH extracts of the stem bark, branches and leaves of Drimys brasiliensis and drimane sesquiterpenes isolated from the stem bark against strains of Leishmania amazonensis and Leishmania braziliensis promastigotes and Plasmodium falciparum trophozoites. All of the extracts and compounds...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Claudino VD,da Silva KC,Cechinel Filho V,Yunes RA,Delle Monache F,Giménez A,Salamanca E,Gutierrez-Yapu D,Malheiros A

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Gene reporter-fluorescent cells have emerged as alternative method for drug screening. OBJECTIVE:Achievement of constitutive expression of fluorescent protein GFP by Leishmania braziliensis as alternative method for drug screening. METHODS:L. braziliensis-GFP was generated using Leishmania tarentolae pLEXS...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bastos MS,Souza LÂ,Onofre TS,Silva A Júnior,Almeida MR,Bressan GC,Fietto JL

更新日期：2017-02-01 00:00:00

abstract：:Applications of flow cytometry to clinical and experimental hematopoietic stem cell transplantation (HSCT) are discussed in this review covering the following topics: diagnosis and classification of lymphohematologic disorders, quantitation of hematopoietic progenitors in the graft, lymphohematopoietic reconstitution ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Voltarelli JC

更新日期：2000-05-01 00:00:00

abstract：:Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequen...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Baio PV,Mota HF,Freitas AD,Gomes DL,Ramos JN,Sant'Anna LO,Souza MC,Camello TC,Hirata Junior R,Vieira VV,Mattos-Guaraldi AL

更新日期：2013-02-01 00:00:00

abstract：:A kinetic study of the cells present in the spleen of BALB/c mice infected with Schistosoma mansoni was carried out. The lymphocytes were evaluated phenotypically with monoclonal antibodies and the effect of splenectomy on the modulation of periovular granuloma was also investigated. The infected mice had proportional...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Arruda SM,Santoro F,Sadigursky M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Intermediate hosts are key organisms in maintaining parasite life cycles, because they can act as amplifiers in the transmission from natural reservoirs to humans. One of the most important groups of intermediate hosts for zoonotic nematode infections are gastropods,slugs and snails. These are essential orga...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Valente R,Robles MDR,Diaz JI

更新日期：2020-11-27 00:00:00

abstract：:We characterized the Plasmodium falciparum antigen 332 (Ag332) which is specifically expressed during the asexual intraerythrocytic cycle of the parasite. The corresponding Pf332 gene has been located in the subtelomeric region of chromosome 11. Furthermore, it is present in all strains so far analyzed and shows marke...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mattei D,Scherf A

更新日期：1992-01-01 00:00:00

abstract：:We present filaria-nested polymerase chain reaction (PCR), which is based on amplification of first internal transcribed spacer rDNA to distinguish three parasitic filarial species (Onchocerca volvulus, Mansonella ozzardi and Mansonella perstans) that can be found in the Amazon Region. Nested PCR-based identifications...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Tang TH,López-Vélez R,Lanza M,Shelley AJ,Rubio JM,Luz SL

更新日期：2010-09-01 00:00:00

abstract：:Six clinical isolates of influenza A viruses were examined for hemagglutinin receptor specificity and neuraminidase substrate specificity. All of the viral isolates minimally passaged in mammalian cells demonstrated preferential agglutination of human erythrocytes enzymatically modified to contain NeuAc alpha 2,6Gal s...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Couceiro JN,Baum LG

更新日期：1994-10-01 00:00:00

abstract：:Lutzomyia evandroi Costa Lima and Antunes, 1936 is found in Rio Grande do Norte, northeastern Brazil, in areas of visceral and mucocutaneous leishmaniasis and follows the same geographic distribution of L. longipalpis. The biological cycle, oviposition, morphological and behavioral characteristics of the species were ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Melo Ximenes Mde F,Maciel JC,Jerônimo SM

更新日期：2001-08-01 00:00:00

abstract：:A 19-month mark-release-recapture study of Neotoma micropus with sequential screening for Leishmania mexicana was conducted in Bexar County, Texas, USA. The overall prevalence rate was 14.7% and the seasonal prevalence rates ranged from 3.8 to 26.7%. Nine incident cases were detected, giving an incidence rate of 15.5/...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Raymond RW,McHugh CP,Witt LR,Kerr SF

更新日期：2003-03-01 00:00:00

abstract：:Anti-human immunodeficiency virus type 1 (HIV-1) "binding antibodies" (antibodies capable of binding to synthetic peptides or proteins) occur throughout HIV-1 infection, are high-titered and highly cross-reactive, as confirmed in this study by analyzing plasma from B and F genotype HIV-1 infected individuals. Plasma f...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bongertz V,Teixeira SL,Grinztejn B,Pilotto JH,Veloso VG,Morgado MG,Bastos FI,Ouverney EP

更新日期：2005-02-01 00:00:00

abstract：:Mutations in the katG gene have been identified and correlated with isoniazid (INH) resistance in Mycobacterium tuberculosis isolates. The mutation AGC-->ACC (Ser-->Thr) at katG315 has been reported to be the most frequent and is associated with transmission and multidrug resistance. Rapid detection of this mutation c...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Verza M,Maschmann Rde A,Silva MS,Dalla Costa ER,Ribeiro MO,Rosso F,Suffys PN,Tortoli E,Marcelli F,Zaha A,Rossetti ML

更新日期：2009-08-01 00:00:00

abstract：:Goats from the Venezuelan northern arid zones were found infested by the following nematodes: Haemonchus contortus, Trichostrongylus axei, T. colubriformis, Cooperia curticei, Oesophagostomum columbianum, Skrjabinema ovis y Trichuris globulosa. The Shannon-Weaver index of diversity values oscillated between 0.045 and ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Morales G,Pino LA,Aldana E,Perdomo L,Molina E

更新日期：1986-04-01 00:00:00

abstract：:In a recent issue of Memórias do Instituto Oswaldo Cruz, published in Rio de Janeiro in February 2014 (109: 87-92), Adami et al. have published a survey reporting Mansonella parasite prevalence in the Amazon Region. This report makes a useful contribution to the existing knowledge of filarial parasite distribution wit...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Luz SL,Crainey JL,Shelley AJ,Rubio M

更新日期：2014-07-01 00:00:00