Natural lectin activity in the haemolymph of Panstrongylus megistus (Heteroptera: Reduviidae).

Abstract:

:The haemolymph of Panstrongylus megistus showed a natural lectin activity for a wide range of vertebrate erythrocytes. Agglutination was observed against all vertebrate erythrocytes tested (human ABO, duck, rabbit, mouse, sheep, chicken and cow). Cow erythrocytes showed the lowest titre. Concerning human erythrocytes, the lectin activity was similar in the types A+, B+ and AB+ while the highest activity was observed in the type O+. Determination of minimal inhibitory concentrations was carried out with human erythrocytes type O+. Agglutination was inhibited by several carbohydrates (rhamnose, D-galactose, raffinose, D-lactose and D-fucose). Rhamnose was reported as the strongest inhibitor (0.78 mM). The results suggest the presence of more than one lectin in the haemolymph of P. megistus.

journal_name

Mem Inst Oswaldo Cruz

authors

Gomes YM,Furtado AF,De Carvalho AB

doi

10.1590/s0074-02761988000400018

subject

Has Abstract

pub_date

1988-10-01 00:00:00

pages

509-12

issue

4

eissn

0074-0276

issn

1678-8060

pii

S0074-02761988000400018

journal_volume

83

pub_type

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