Assessment of Gastric Emptying Times Between Pediatrics and Adults With Cyclic Vomiting Syndrome.

Abstract:

BACKGROUND & AIMS:Cyclic vomiting syndrome (CVS) is characterized by episodes of nausea and vomiting separated by symptom-free intervals. Rome IV guidelines have now distinguished CVS from other disorders such as cannabinoid hyperemesis. The pathogenesis of CVS, however, is poorly understood. Limited data exist on gastric emptying (GE) in patients with CVS. Therefore, the authors aim to measure the GE profile in pediatrics and adults with CVS. MATERIALS AND METHODS:Patients with the diagnosis of CVS (per NASPGHAN and Rome IV) between December 1998 and March 2017 who underwent gastric emptying study (GES) and without documented cannabis use were included. Clinical features including demographics, medication use, and comorbidities were also recorded. Frequency of rapid, normal, and delayed emptying was reported, and multinomial univariate logistic regression was used to identify factors associated with each type of emptying. KEY RESULTS:Sixty-seven subjects were included (50.7% female individuals, pediatrics n=15, adults n=52). At 2-hour retention, 40% of pediatric patients met criteria for rapid, 33.3% for normal, and 26.7% for delayed GE. In adults, 50% met criteria for rapid, 46.2% for normal, and 3.8% for delayed GE. For every 5-year increase in age, odds of rapid emptying on GES increased. CONCLUSIONS:(1) GE is predominantly rapid at 2 hours in pediatrics and adults with CVS. (2) Rapid GE seems to increase with age. (3) Current guidelines do not recommend GE in the initial management, however, further studies may play a role to help differentiate CVS from other functional gastric disorders.

journal_name

J Clin Gastroenterol

authors

Kamal A,Sarvepalli S,Selvakumar P,Lopez R,Radhakrishnan K,Gabbard S

doi

10.1097/MCG.0000000000001352

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

e89-e92

issue

9

eissn

0192-0790

issn

1539-2031

journal_volume

54

pub_type

杂志文章
  • Pilot study of the relationship between histologic progression and hepatic iron concentration in chronic hepatitis C.

    abstract::Hepatic iron deposition is common in patients with chronic hepatitis C (HCV) and may play a role in progression of liver disease. This pilot study examines the relationship between hepatic iron concentration (HIC) and histologic progression over time in patients with HCV. HIC was retrospectively measured in 14 patient...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200311000-00012

    authors: Larson AM,Taylor SL,Bauermeister D,Rosoff L Jr,Kowdley KV

    更新日期:2003-11-01 00:00:00

  • Effects of microencapsulated vs. enteric-coated acetylsalicylic acid on gastric and duodenal mucosa: an endoscopic study.

    abstract::Two preparations of acetylsalicylic acid (ASA) were tested for their effects on gastroduodenal mucosa in a randomized crossover double-blind study that involved 12 healthy volunteers. Medication M (Monobeltin) consisted of 1,050 mg ASA provided with an enteric coat and medication C (Colfarit) consisted of 1,000 mg of ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004836-198806000-00008

    authors: Malfertheiner P,Stanescu A,Rogatti W,Ditschuneit H

    更新日期:1988-06-01 00:00:00

  • Nortriptyline-induced fulminant hepatic failure.

    abstract::We describe, to our knowledge, the first reported case of nortriptyline-induced fulminant hepatic failure. This tricyclic antidepressant drug was taken by a postmenopausal woman for 64 days before her presentation. The absence of fever, rash, or marked eosinophilia, the predominant zone 3 necrosis with bridging, and t...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199501000-00014

    authors: Berkelhammer C,Kher N,Berry C,Largosa A

    更新日期:1995-01-01 00:00:00

  • Risk Factors and Outcomes of Reversal Agent Use in Moderate Sedation During Endoscopy and Colonoscopy.

    abstract:BACKGROUND:Moderate sedation has been standard for noninvasive gastrointestinal procedures for decades yet there are limited data on reversal agent use and outcomes associated with need for reversal of sedation. AIM:To determine prevalence and clinical significance of reversal agent use during endoscopies and colonosc...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000291

    authors: Hung A,Marshall J,Barnett S,Falchuk ZM,Sawhney M,Leffler DA

    更新日期:2016-03-01 00:00:00

  • Celiac sprue, hyperhomocysteinemia, and MTHFR gene variants.

    abstract:GOALS:To describe the association of untreated celiac disease with hyperhomocysteinemia and variants of the methylenetetrahydrofolicacid reductase (MTHFR) gene found in clinical practice. STUDY:Case studies with description of associated clinical, biochemical, and genetic findings and review of literature. RESULTS:Fi...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200608000-00007

    authors: Wilcox GM,Mattia AR

    更新日期:2006-08-01 00:00:00

  • Mesalazine for the Treatment of Symptomatic Uncomplicated Diverticular Disease of the Colon and for Primary Prevention of Diverticulitis: A Systematic Review of Randomized Clinical Trials.

    abstract:BACKGROUND:Symptomatic uncomplicated diverticular disease (SUDD) is a common gastrointestinal disease, because it affects about one fourth of the patient harboring colonic diverticula. GOAL:To assess the effectiveness of mesalazine in improving symptoms (namely abdominal pain) and in preventing diverticulitis occurren...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0000000000000669

    authors: Picchio M,Elisei W,Brandimarte G,Di Mario F,Malfertheiner P,Scarpignato C,Tursi A

    更新日期:2016-10-01 00:00:00

  • Alcohol consumption is inversely correlated with insulin resistance, independent of metabolic syndrome factors and fatty liver diseases.

    abstract:BACKGROUND AND AIM:The role of alcohol consumption in insulin resistance remains unclear. The aim of this study was to examine the association between alcohol consumption and insulin resistance in a large asymptomatic population. METHODS:A total of 2463 asymptomatic Japanese men aged 28 years or above undergoing a com...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e318223bd53

    authors: Gunji T,Matsuhashi N,Sato H,Iijima K,Fujibayashi K,Okumura M,Sasabe N,Urabe A

    更新日期:2011-10-01 00:00:00

  • Acute hepatotoxicity from ingestion of yellow phosphorus-containing fireworks.

    abstract::We reviewed 15 cases of poisoning from ingestion of yellow phosphorus-containing fireworks and analyzed its associated acute hepatotoxic effects. Two patients (13%) had no clinical or biochemical evidence of hepatic damage, four (27%) had subclinical hepatic injury, five (33%) manifested varying degrees of hepatocellu...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199509000-00015

    authors: Fernandez OU,Canizares LL

    更新日期:1995-09-01 00:00:00

  • Probiotics and Evidence-based Medicine: To All Involved: We have a Problem.

    abstract::The methods used to discern the structure (anatomy) and function (physiology) of the indigenous microbiota can be divided according to which aspect of the microbiota they can interrogate and are positioned accordingly. At the most basic level, methods can simply describe the community structure of the microbiota, that...

    journal_title:Journal of clinical gastroenterology

    pub_type:

    doi:10.1097/MCG.0000000000001106

    authors: Koch M

    更新日期:2018-11-01 00:00:00

  • Push enteroscopy in the era of capsule endoscopy.

    abstract:GOALS:To evaluate the diagnostic yield of push enteroscopy in relation to indication and compare the yield in patients who had capsule endoscopy followed by push enteroscopy against capsule endoscopy naive patients. BACKGROUND:With the advent of capsule endoscopy the role of push enteroscopy needs to be reevaluated. ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/01.mcg.0000225655.85060.74

    authors: Sidhu R,McAlindon ME,Kapur K,Hurlstone DP,Wheeldon MC,Sanders DS

    更新日期:2008-01-01 00:00:00

  • Macrophage activation syndrome: why and what should a gastroenterologist know.

    abstract::We recently treated a patient with adult-onset Still's disease who developed macrophage activation syndrome (MAS) secondary to disseminated histoplasmosis while being treated with adalimumab. The gastroenterology service was consulted early, before diagnosis, as the patient presented with elevated liver enzymes and di...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0b013e3181f6015f

    authors: Jayakar BA,Hashkes PJ

    更新日期:2011-03-01 00:00:00

  • Efficacy of tricyclic antidepressant therapy in adults with cyclic vomiting syndrome: a two-year follow-up study.

    abstract:AIM:To investigate the effects of prolonged tricyclic antidepressants (TCAs) therapy on the frequency and duration of episodes of cyclic vomiting syndrome (CVS) in adults, and the global assessment of clinical improvement and the number of emergency department (ED) visits and/or hospitalizations. METHOD:An open labele...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1097/MCG.0b013e3181ac6489

    authors: Hejazi RA,Reddymasu SC,Namin F,Lavenbarg T,Foran P,McCallum RW

    更新日期:2010-01-01 00:00:00

  • Consider the perspectives: interventional radiology.

    abstract::Image-guided percutaneous local and regional modalities are major treatments for hepatocellular carcinoma. Patients having better liver function and performance are usually eligible and can gain significant survival benefit, especially with more limited tumor burden. The most common local therapies are ethanol and rad...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e31828be6f0

    authors: Pollak JS

    更新日期:2013-07-01 00:00:00

  • Treatment of benign chronic gastric ulcer with ranitidine. A randomized, double-blind, and placebo-controlled six week trial.

    abstract::A randomized, multicenter, double-blind, placebo-controlled study was conducted to determine whether ranitidine 150 mg b.i.d. for 6 weeks would expedite endoscopic healing or relief of symptoms in patients with benign gastric ulcer. Of 203 patients enrolled, 101 received ranitidine and 102 received placebo. Endoscopic...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004836-198606002-00008

    authors: Hirschowitz BI,DeLuca V,Graham D,Lorber S,Bright-Asare P,Katon R

    更新日期:1986-06-01 00:00:00

  • Comparison of transjugular intrahepatic portosystemic shunt (TIPS) alone versus TIPS combined with embolotherapy in advanced cirrhosis: a retrospective study.

    abstract:OBJECTIVE:This study was designed to determine whether a transjugular intrahepatic portosystemic shunt (TIPS) combined with embolotherapy was superior to TIPS alone. METHODS:Seventy-nine patients were included in the study (43 in the TIPS and embolotherapy group and 36 in the TIPS alone group). Embolotherapy was perfo...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e318203dfb3

    authors: Xiao T,Chen L,Chen W,Xu B,Long Q,Li R,Li L,Peng Z,Fang D,Wang R

    更新日期:2011-08-01 00:00:00

  • Early or delayed endoscopy for patients with peptic ulcer bleeding. A prospective randomized study.

    abstract::The benefit of early endoscopy in the management of peptic ulcer bleeding remains controversial. In this study we looked at the role of early endoscopy in bleeding peptic ulcer patients with clear, "coffee grounds," or bloody nasogastric aspirate. A consecutive series of 325 patients with peptic ulcer bleeding were in...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004836-199606000-00005

    authors: Lin HJ,Wang K,Perng CL,Chua RT,Lee FY,Lee CH,Lee SD

    更新日期:1996-06-01 00:00:00

  • Eleven-year survey of safety and efficacy of endoscopic injection sclerotherapy using 2% sodium tetradecyl sulfate and contrast medium.

    abstract::We conducted a retrospective 11-year survey to evaluate the post-treatment course in 285 patients with esophagogastric varices following administration of endoscopic injection sclerotherapy as an emergency, elective, or prophylactic procedure using freshly prepared 2% sodium tetradecyl sulfate not containing benzyl al...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199601000-00017

    authors: Iwase H,Suga S,Shimada M,Yamada H,Horiuchi Y,Oohashi M

    更新日期:1996-01-01 00:00:00

  • Efficacy of low-dose antacids in the treatment of peptic ulcers: pharmacological explanation?

    abstract::Antacids have been used as remedies for benign gastroduodenal disorders for centuries. They were regarded to be effective in relieving gastric pain and symptoms of hyperacidity and in promoting ulcer healing. The effectiveness was based on empiric observations and was not derived from the controlled clinical trials da...

    journal_title:Journal of clinical gastroenterology

    pub_type: 临床试验,杂志文章,meta分析

    doi:10.1097/00004836-199112001-00022

    authors: Sewing KF

    更新日期:1991-01-01 00:00:00

  • Irritable bowel syndrome subtypes defined by Rome II and Rome III criteria are similar.

    abstract:BACKGROUND:The implications of the Rome III recommendations to change the irritable bowel syndrome (IBS) subtype criteria for stool pattern are unknown. AIM:(1) Determine the level of agreement between Rome II and Rome III subtypes and (2) compare the behaviors of Rome II and Rome III subtypes over time. METHODS:Fema...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e31815bd749

    authors: Dorn SD,Morris CB,Hu Y,Toner BB,Diamant N,Whitehead WE,Bangdiwala SI,Drossman DA

    更新日期:2009-03-01 00:00:00

  • Biliary atresia: recent progress.

    abstract::Extrahepatic biliary atresia (EHBA), an inflammatory sclerosing cholangiopathy, is the leading indication for liver transplantation in children. The cause is still unknown, although possible infectious, genetic, and immunologic etiologies have received much recent focus. These theories are often dependent on each othe...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0b013e3181646730

    authors: Bassett MD,Murray KF

    更新日期:2008-07-01 00:00:00

  • Extraesophageal malignancies among patients with Barrett esophagus.

    abstract:GOALS:To evaluate the incidence of extraesophageal malignancies among patients with Barrett esophagus (BE). BACKGROUND:Gastroesophageal reflux disease has been reported to be associated with upper aerodigestive malignancies. BE is considered a consequence of long-standing gastroesophageal reflux disease; however, the ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e31828bf26f

    authors: Pines G,Dickman R,Niv Y,Kashtan H,Birkenfeld S

    更新日期:2014-01-01 00:00:00

  • Role of hepatitis B surface antigen (HBsAg) in identifying true inactive HBsAg carriers infected with genotype C hepatitis B virus.

    abstract:BACKGROUND:Inactive and active phases of hepatitis B e antigen-negative chronic hepatitis B virus (HBV) infection are diagnosed by serum HBV DNA levels, with cutoff at 2000 IU/mL. However, it is difficult to distinguish inactive carriers at a single time point because HBV DNA levels can transiently decrease to <2000 IU...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0b013e3182a4711d

    authors: Yim SY,Um SH,Jung JY,Seo YS,Yim HJ,Ryu HS,Chun HJ,Jeen YT,Kim CD,Keum B,Lee HS

    更新日期:2014-02-01 00:00:00

  • Predictors of Gastrin Elevation Following Proton Pump Inhibitor Therapy.

    abstract:GOALS:The goal of this study was to elucidate the most important predictors for elevation of gastrin in patients on long-term PPI therapy through analysis of data from 2 published studies in Icelandic patients with erosive GERD. BACKGROUND:Gastrin elevation is a known but variable consequence of proton pump inhibitor ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000001200

    authors: Helgadóttir H,Lund SH,Gizurarson S,Metz DC,Björnsson ES

    更新日期:2020-03-01 00:00:00

  • Open access endoscopy: a large-scale analysis of its use in dyspeptic patients.

    abstract::We examined 2,253 consecutive dyspeptic patients referred to our endoscopy service by general practitioners ("open" group) and hospital clinicians ("clinic" group) to study the prevalence of the various endoscopic findings according to patient age and the route of endoscopic referral. The results obtained are represen...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Mansi C,Mela GS,Savarino V,Mele MR,Valle F,Celle G

    更新日期:1993-03-01 00:00:00

  • Hydrogen peroxide colitis: a report of three patients.

    abstract::We have seen three patients with acute ulcerative colitis after hydrogen peroxide enemas. The colitis is probably the result of the explosive entrance of gas into the loose connective tissues of the mucosa and submucosa of the rectum and sigmoid. Fortunately, it is transitory in nature, but it should be distinguished ...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-198103000-00008

    authors: Meyer CT,Brand M,DeLuca VA,Spiro HM

    更新日期:1981-03-01 00:00:00

  • Current Management of Patients With Diverticulosis and Diverticular Disease: A Survey From the 2nd International Symposium on Diverticular Disease.

    abstract:BACKGROUND:Management of diverticular disease (DD) remains a point of debate. GOALS:To investigate the current opinion of participants of the 2nd International Symposium on Diverticular Disease, on real-life management of patients with DD of the colon. STUDY:Twelve questions were aimed at the diagnosis, treatment, an...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000645

    authors: Tursi A,Picchio M,Elisei W,Di Mario F,Scarpignato C,Brandimarte G

    更新日期:2016-10-01 00:00:00

  • Exclusion of the meal period improves the clinical reliability of esophageal pH monitoring.

    abstract::Meal period exclusion from 24-h pH testing allows better separation between controls and patients with gastroesophageal reflux disease. We reviewed the results of 24-h pH studies of 350 patients with reflux symptoms. They were divided into two groups based on the 95th percentile of the total percentage of time when pH...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-199707000-00003

    authors: Ter RB,Johnston BT,Castell DO

    更新日期:1997-07-01 00:00:00

  • Terminal ileum resection is associated with higher plasma homocysteine levels in Crohn's disease.

    abstract:BACKGROUND:Elevated plasma total homocysteine (tHcy) is associated with a higher risk of thrombosis. Crohn's disease (CD) is associated with hypercoagulability of undefined etiology. We investigated tHcy in patients with CD and its relationship with vitamin status, disease activity, location, duration, and history of t...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00004836-200108000-00008

    authors: Vasilopoulos S,Saiean K,Emmons J,Berger WL,Abu-Hajir M,Seetharam B,Binion DG

    更新日期:2001-08-01 00:00:00

  • Importance of Patients' Knowledge of Their Prescribed Medication in Improving Treatment Adherence in Inflammatory Bowel Disease.

    abstract:GOALS:To investigate the association between treatment nonadherence and patients' knowledge of the prescribed medication among individuals with inflammatory bowel disease (IBD), and evaluate the impact of nonadherence on relapse. BACKGROUND:The patient's knowledge of the prescribed medication has been identified as an...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MCG.0000000000000431

    authors: Tae CH,Jung SA,Moon HS,Seo JA,Song HK,Moon CM,Kim SE,Shim KN,Jung HK

    更新日期:2016-02-01 00:00:00

  • The role of nutrients in the development, progression, and treatment of nonalcoholic fatty liver disease.

    abstract::Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in adults and children and is currently the third most common indication for liver transplantation in North America. Its pathogenesis is thought to be secondary to multiple "hits" derived from the dietary components, adipose tissue, imm...

    journal_title:Journal of clinical gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MCG.0b013e31824cf51e

    authors: Mouzaki M,Allard JP

    更新日期:2012-07-01 00:00:00