Abstract:
:Gastrointestinal (GI) disturbances are common during training and competition, especially among endurance athletes. Historically, little attention has been paid to the psychobiological etiology of GI problems in sport. The aim of this review is to: (1) provide a physiological overview of how psychological stress and anxiety impact GI system function; (2) review the literature that has examined the role of stress and anxiety in GI distress in athletes; and (3) provide suggestions for future research. Animal and human studies have documented that psychological stressors reduce gastric motility and delay stomach emptying while simultaneously increasing large intestine motility. These functional changes are likely mediated through the secretion of corticotropin-releasing factor and subsequent alterations in autonomic nervous system activity, which act to reduce splanchnic blood flow and increase GI permeability. In addition, chronic stress and anxiety may worsen GI discomfort by increasing visceral hypersensitization. Still, only a couple of studies have found modest associations between stress, anxiety, and the occurrence/severity of GI distress in active populations. As such, future work should attempt to confirm that experimentally inducing psychological stress results in the aforementioned GI problems during exercise. Furthermore, studies are needed to determine how psychological stress impacts the tolerance to nutritional fueling and whether it worsens the GI permeability that normally occurs with exercise.
journal_name
J Clin Gastroenteroljournal_title
Journal of clinical gastroenterologyauthors
Wilson PBdoi
10.1097/MCG.0000000000001308subject
Has Abstractpub_date
2020-04-01 00:00:00pages
297-304issue
4eissn
0192-0790issn
1539-2031journal_volume
54pub_type
杂志文章abstract::Esophageal function was evaluated in 51 children less than 2 years of age with radiologic evidence of gastroesophageal reflux. Detection of an acid esophageal pH was a sensitive measure of gastroesophageal reflux. Lower esophageal sphincter pressures were greater in reflux patients with respiratory symptoms (18.0 +/- ...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-197906000-00004
更新日期:1979-06-01 00:00:00
abstract::Unbuffered rapid urease test (RUT) is an accurate, rapid, and inexpensive method of detecting Helicobacter pylori. However, it is generally recommended to prepare the reagent daily. This prospective study was undertaken to evaluate the shelf-life of our unbuffered RUT at -20 degrees C. Two sets of antral biopsies (X2)...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-200009000-00010
更新日期:2000-09-01 00:00:00
abstract::A case of heterotopic liver of the jejunum confirmed by electron microscopy in a 2-year-old girl is described. We review the literature regarding heterotopic liver and discuss its embryogenesis. We suggest that in our case, there was trapping of hepatocyte-destined mesenchyme prior to biliary tree development. ...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/00004836-198908000-00024
更新日期:1989-08-01 00:00:00
abstract::Associations between diverticular disease of the colon and the colorectal cancer has been studied for >60 years. Observational, cross-sectional, and case-control studies as well as large population-based studies gave conflicting results and association was not fully proven. Obtaining the proof was difficult because bo...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/MCG.0000000000000643
更新日期:2016-10-01 00:00:00
abstract::Uncontrolled hemorrhage and multisystem organ failure developed in a patient with celiac sprue, lymphocytic gastritis, and diffuse gastric ulceration. A proximal small bowel biopsy showed villous atrophy and lymphoplasmacytic infiltration consistent with celiac sprue. At autopsy, there were no gross or histologic find...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-199707000-00013
更新日期:1997-07-01 00:00:00
abstract:GOAL:The goal of this study was to assess the relationship between pretransplant measures of reflux and longer-term outcomes of chronic allograft rejection in lung transplant recipients. BACKGROUND:Bronchiolitis obliterans syndrome (BOS) is a primary measure of morbidity and mortality following lung transplantation, a...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/MCG.0000000000001331
更新日期:2020-07-01 00:00:00
abstract::A 41-year-old man with human immunodeficiency virus (HIV) (CD4 count, 446/mm3) developed a protracted course of abdominal pain, weight loss, and increasing liver function tests after undergoing a metronidazole treatment regimen for Giardia enteritis. Three months later, endoscopic retrograde cholangiography (ERCP) sho...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-200108000-00018
更新日期:2001-08-01 00:00:00
abstract::A unique case of granulomatous gastritis of unknown etiology is reported. The patient, a 43-year-old Haitian woman, suffered a gastric perforation from a disease process limited to the stomach. The stomach was markedly enlarged and edematous with transmural, serpiginous granulomatous tracks throughout the gastric wall...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-198302000-00013
更新日期:1983-02-01 00:00:00
abstract::To determine the mechanisms of gastric mucosal injury associated with Helicobacter pylori infection, we investigated the contents of cytokines and inflammatory cell infiltration in the gastric mucosa. Ninety-six patients with dyspepsia were studied (58 gastric ulcer, 38 nonulcer dyspepsia). Of the 96 patients, 63 were...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-199700001-00033
更新日期:1997-01-01 00:00:00
abstract::The term indeterminate colitis (IC) is an interim, or preliminary, descriptive term used by pathologists for cases of inflammatory bowel disease (IBD) in which a definite diagnosis of ulcerative colitis (UC) or Crohn's disease (CD) cannot be established based on the information available at the time of surgical sign-o...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/01.mcg.0000127686.69276.5b
更新日期:2004-05-01 00:00:00
abstract::Gastroesophageal reflux disease, especially when refractory to standard therapy, remains a significant clinical problem. Although symptom pathogenesis in erosive reflux disease is relatively easy to understand, it is less clear how exposure of the macroscopically normal mucosa in nonerosive reflux disease (NERD) is ab...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MCG.0b013e318299f181
更新日期:2014-01-01 00:00:00
abstract::The present study was designed to assess histologic and ultrastructural features of gastric mucosa in the areas of grossly healed ulcers (acetic acid-induced gastric ulcers) in rats. The specific question we studied was whether the structure and cellular composition of the gastric mucosa in an area of grossly healed u...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-199001001-00024
更新日期:1990-01-01 00:00:00
abstract::We studied a young man with persistent elevation of transaminases and indirect bilirubin following acute viral hepatitis. Liver biopsy showed chronic persistent hepatitis, and clinical evaluation was otherwise negative for significant liver disease. The indirect-reacting serum bilirubin rose after both caloric restric...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-198103000-00010
更新日期:1981-03-01 00:00:00
abstract::We reviewed 15 cases of poisoning from ingestion of yellow phosphorus-containing fireworks and analyzed its associated acute hepatotoxic effects. Two patients (13%) had no clinical or biochemical evidence of hepatic damage, four (27%) had subclinical hepatic injury, five (33%) manifested varying degrees of hepatocellu...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-199509000-00015
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND AND AIMS:The occurrence of reflux disease seems to be rising in the United States. The aim of the present study was to follow the time trends of hospitalization for gastroesophageal reflux disease (GERD) and other esophageal disease during the past 4 decades. METHODS:US hospital utilization data were availa...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/MCG.0000000000000023
更新日期:2014-09-01 00:00:00
abstract::The intensity of diagnostic workup of patients with human immunodeficiency virus (HIV)-related chronic diarrhea is controversial. In the ideal setting in which an enteric pathogen is detected with minimal evaluation (stool tests) and in which specific treatment clears the diarrhea, eradicates the pathogen, and improve...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/00004836-199304000-00018
更新日期:1993-04-01 00:00:00
abstract:GOALS:To determine the proportion of patients with gastroesophageal reflux disease who are on proton pump inhibitors (PPIs) who could reduce their prior dosage by half, and identify predictors of successful step-down. BACKGROUND:Appropriate hypergastrinemia results from gastric acid inhibition. A gender difference in ...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,随机对照试验
doi:10.1097/MCG.0000000000000542
更新日期:2017-07-01 00:00:00
abstract::Human and animal stomachs were considered the only reservoirs of Helicobacter pylori until it was identified in human dental plaque (DP). H. pylori is infrequent in populations from developed countries, but is widespread in those from developing countries. The failure of triple drug therapy to clear H. pylori from DP,...
journal_title:Journal of clinical gastroenterology
pub_type: 社论
doi:
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:There was some ambiguity in the recent guidelines on the use of capsule endoscopy (CE) in cases of iron deficiency anemia (IDA). GOAL:We aimed to examine the yield of CE in diagnosing the cause of IDA and to define clinical parameters that predict higher diagnostic yields. MATERIALS AND METHODS:A total of ...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/MCG.0000000000001255
更新日期:2020-05-01 00:00:00
abstract::A 53-year-old white woman developed diabetes mellitus, migratory erythema, and anemia, clinical features suggesting the presence of a "glucagonoma." Ten years earlier, after laparotomy and pancreatic biopsy, she had been told that she had an inoperable pancreatic carcinoma. Review of that biopsy together with current ...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-197909000-00005
更新日期:1979-09-01 00:00:00
abstract:GOALS:We determined yearly rates of upper and lower gastrointestinal (GI) hospitalizations in Quebec, Canada and compared the 1-year readmission and mortality risks among those discharged from lower versus upper GI hospitalizations. BACKGROUND:The burden of serious upper and lower GI events is substantial. STUDY:Demo...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/MCG.0b013e318282a1d7
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Hepatitis C virus genotype differences seem to be of considerable clinical significance because they affect responses to antiviral therapy. HCV genotype 4 is rare in the United States and there are few published data regarding response to therapy in patients with HCV genotype 4 infection. OBJECTIVES:To asse...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-200401000-00014
更新日期:2004-01-01 00:00:00
abstract::Lansoprazole, a proton pump inhibitor, has been reported to inhibit ethanol-induced injury in rats. However, the mechanism of the protective effect is not known. This study was carried out to investigate the role of prostaglandin (PG) in the protective effect of lansoprazole. Male Wistar rats were given either 30 mg/k...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-199506002-00003
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:There has been constant speculation about the association between metabolic syndrome (MetS) and colorectal neoplasia (CN); however, the published results are conflicting. The aims of this study are to conduct a systematic search, and assess the literature to determine the available evidence on the associatio...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MCG.0b013e3182688c15
更新日期:2013-01-01 00:00:00
abstract::Between 1978 and 1989, 13 of 48 patients with anomalous union of the pancreaticobiliary ductal system (AUPBD) were diagnosed as having acute pancreatitis. We have studied the clinical, radiologic, and surgical features of these 13 patients. A transient rise in the intraductal pressure of the pancreatic duct during an ...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-199112000-00012
更新日期:1991-12-01 00:00:00
abstract::Twenty consecutive patients with unresectable, locally advanced pancreatic cancer were treated with split courses of radiotherapy (RT) and simultaneous multidrug chemotherapy consisting of 5 fluorouracil, continuous infusion, streptozotocin, and cisplatin. A separate, retrospective study identified a group of 28 conte...
journal_title:Journal of clinical gastroenterology
pub_type: 临床试验,杂志文章
doi:10.1097/00004836-199304000-00006
更新日期:1993-04-01 00:00:00
abstract:GOALS:To evaluate the impact of age on the prognosis of patients with hepatocellular carcinoma (HCC) undergoing percutaneous radiofrequency ablation (RFA). BACKGROUND:Whether age plays an important role in the outcomes of HCC after RFA remains controversial. STUDY:Two hundred fifty-eight consecutive treatment naive H...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/MCG.0b013e31822b36cc
更新日期:2012-01-01 00:00:00
abstract::6-mercaptopurine (6-MP) and azathioprine (AZA) are used to treat inflammatory bowel disease (IBD). Side effects include infection, leukopenia, hepatitis, and pancreatitis. The level of thiopurine methyltransferase (TPMT), which metabolizes 6-MP to 6-methylmercaptopurine, may reflect the risk of side effects. We sought...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-200006000-00011
更新日期:2000-06-01 00:00:00
abstract::A case of an ulcerated gastric wall mass ultimately found to be splenosis is presented in which the index patient had endoscopic and endoscopic ultrasonographic evaluation prior to resection. Although no visual features identified this mass as a splenic implant preoperatively, the lesion appeared to be atypical for le...
journal_title:Journal of clinical gastroenterology
pub_type: 杂志文章
doi:10.1097/00004836-199904000-00020
更新日期:1999-04-01 00:00:00
abstract::In a double-blind placebo-controlled study, we examined the effect of calcitonin on gastric emptying, and on serum concentrations of gastrin, insulin, glucose, calcium, and phosphorus after a mixed solid-liquid meal in 11 healthy men. Synthetic salmon calcitonin was administered as a 415 pmol i.v. bolus injection foll...
journal_title:Journal of clinical gastroenterology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004836-199002000-00007
更新日期:1990-02-01 00:00:00