A Review on the Effect of Plant Extract on Mesenchymal Stem Cell Proliferation and Differentiation.

abstract：:Branching morphogenesis (BrM), an essential step for salivary gland development, requires epithelial-mesenchymal interactions. BrM is impaired when the surrounding mesenchyme is detached from the salivary epithelium during the pseudoglandular stage. It is believed that the salivary mesenchyme is indispensable for BrM,...

journal_title：Stem cells international

authors： Okumura K,Shinohara M,Endo F

更新日期：2012-01-01 00:00:00

abstract：:The objective of this paper is to describe in detail the method of organotypic longitudinal spinal cord slice culture and the scientific basis for its potential utility. The technique is based on the interface method, which was described previously and thereafter was modified in our laboratory. The most important adva...

journal_title：Stem cells international

authors： Sypecka J,Koniusz S,Kawalec M,Sarnowska A

更新日期：2015-01-01 00:00:00

abstract：:A major challenge in cartilage repair is the lack of chondrogenic cells migrating from healthy tissue into damaged areas and strategies to promote this should be developed. The aim of this study was to evaluate the effect of peripheral blood derived mononuclear cell (PBMC) stimulation on mesenchymal stromal cells (MSC...

journal_title：Stem cells international

authors： Hopper N,Wardale J,Howard D,Brooks R,Rushton N,Henson F

更新日期：2015-01-01 00:00:00

abstract：:Oxidative stress leads to the degeneration of retinal pigment epithelial (RPE) and photoreceptor cells. We evaluated the potential of adipose-derived mesenchymal stem cells (ASCs) as a therapeutic tool by studying the migration capacity of ASCs in vitro and their protective effect against RPE cell death under oxidativ...

journal_title：Stem cells international

authors： Barzelay A,Weisthal Algor S,Niztan A,Katz S,Benhamou M,Nakdimon I,Azmon N,Gozlan S,Mezad-Koursh D,Neudorfer M,Goldstein M,Meilik B,Loewenstein A,Barak A

更新日期：2018-12-13 00:00:00

abstract：:We have determined the protective effects of Thymus serpyllum (TS) extract and nanoparticle-loaded TS on hydrogen peroxide-induced cell death of mesenchymal stromal cells (MSCs) in vitro. Gas chromatography-mass spectroscopy confirmed the spectrum of active components in the extract. Out of the three different extract...

journal_title：Stem cells international

authors： Baig S,Azizan AHS,Raghavendran HRB,Natarajan E,Naveen S,Murali MR,Nam HY,Kamarul T

更新日期：2019-02-26 00:00:00

abstract：:Neuromuscular diseases are caused by functional defects of skeletal muscles, directly via muscle pathology or indirectly via disruption of the nervous system. Extensive studies have been performed to improve the outcomes of therapies; however, effective treatment strategies have not been fully established for any majo...

journal_title：Stem cells international

authors： Jiwlawat N,Lynch E,Jeffrey J,Van Dyke JM,Suzuki M

更新日期：2018-04-11 00:00:00

abstract：Background:While regenerative stem cell therapy for ischemic heart disease has moved into phase 3 studies, little is still known about retention and migration of cell posttransplantation. In human studies, the ability to track transplanted cells has been limited to labeling with radioisotopes and tracking using nuclear...

journal_title：Stem cells international

authors： Mathiasen AB,Qayyum AA,Jørgensen E,Helqvist S,Ekblond A,Ng M,Bhakoo K,Kastrup J

更新日期：2019-11-14 00:00:00

abstract：:The purpose of this study is to determine if patients with chronic patellar tendinopathy will improve clinically after the inoculation of bone marrow mononuclear cells (BM-MNCs). Eight patients with chronic patellar tendinopathy were included. Patients averaged 24 years old (range 14-35). All patients were refractory ...

journal_title：Stem cells international

authors： Pascual-Garrido C,Rolón A,Makino A

更新日期：2012-01-01 00:00:00

abstract：:Histone deacetylase inhibitors (HDACi) are small molecules that have important and pleiotropic effects on cell homeostasis. Under distinct developmental conditions, they can promote either self-renewal or differentiation of embryonic stem cells. In addition, they can promote directed differentiation of embryonic and t...

journal_title：Stem cells international

authors： Kretsovali A,Hadjimichael C,Charmpilas N

更新日期：2012-01-01 00:00:00

abstract：:Human bone marrow mesenchymal stem cells (hBM-MSCs) are the best characterized multipotent adult stem cells. Their self-renewal capacity, multilineage differentiation potential, and immunomodulatory properties have indicated that they can be used in many clinical therapies. In a previous work we studied the DNA methyl...

journal_title：Stem cells international

authors： Bentivegna A,Roversi G,Riva G,Paoletta L,Redaelli S,Miloso M,Tredici G,Dalprà L

更新日期：2016-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are a reliable source for cell-based regenerative medicine owing to their multipotency and biological functions. However, aging-induced systemic homeostasis disorders in vivo and cell culture passaging in vitro induce a functional decline of MSCs, switching MSCs to a senescent status with...

journal_title：Stem cells international

authors： Wang R,Wang Y,Zhu L,Liu Y,Li W

更新日期：2020-09-10 00:00:00

abstract：:Ion channels orchestrate directed flux of ions through membranes and are essential for a wide range of physiological processes including depolarization and repolarization of biomechanical activity of cells. Besides their electrophysiological functions in the heart, recent findings have demonstrated that ion channels a...

journal_title：Stem cells international

authors： Keßler M,Just S,Rottbauer W

更新日期：2012-01-01 00:00:00

abstract：:Urine has become the source of choice for noninvasive renal epithelial cells and renal stem cells which can be used for generating induced pluripotent stem cells. The aim of this study was to generate a 3D nephrogenic progenitor cell model composed of three distinct cell types-urine-derived SIX2-positive renal progeni...

journal_title：Stem cells international

authors： Nguyen L,Spitzhorn LS,Adjaye J

更新日期：2019-05-02 00:00:00

abstract：:Damage to the nervous system can cause devastating diseases or musculoskeletal dysfunctions and transplantation of progenitor stem cells can be an excellent treatment option in this regard. Preclinical studies demonstrate that untreated stem cells, unlike stem cells activated to differentiate into neuronal lineage, do...

journal_title：Stem cells international

authors： Madhu V,Dighe AS,Cui Q,Deal DN

更新日期：2016-01-01 00:00:00

abstract：:Left-right symmetry breaking is a complex developmental process and an important part of embryonic axis development. As of yet, the biophysical mechanism behind LR asymmetry establishment remains elusive for the overall asymmetry of embryos as well as for the organ-specific asymmetry. Here, we demonstrate that inheren...

journal_title：Stem cells international

authors： Worley KE,Chin AS,Wan LQ

更新日期：2018-12-02 00:00:00

abstract：:Myocarditis is a common inflammatory cardiomyopathy, associated with cardiomyocyte apoptosis, which can lead to chronic left ventricular dysfunction. Under conventional heart failure therapy, inflammatory cardiomyopathy typically has a progressive course, indicating a need for alternative therapeutic strategies to imp...

journal_title：Stem cells international

authors： Miteva K,Van Linthout S,Volk HD,Tschöpe C

更新日期：2013-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2015/496512.]. ...

journal_title：Stem cells international

authors： Sasi SP,Park D,Muralidharan S,Wage J,Kiladjian A,Onufrak J,Enderling H,Yan X,Goukassian DA

更新日期：2016-01-01 00:00:00

abstract：:Previous studies have demonstrated that myocardin-related transcription factor A (MRTF-A) generates a link between the dynamics of the actin cytoskeleton and gene expression with its coregulator, serum response factor (SRF). MRTF-A has also been suggested as a regulator of stem cell differentiation. However, the role ...

journal_title：Stem cells international

authors： Hyväri L,Vanhatupa S,Halonen HT,Kääriäinen M,Miettinen S

更新日期：2020-09-22 00:00:00

abstract：:Aging of population brings related social problems, such as muscle attenuation and regeneration barriers with increased aging. Muscle repair and regeneration depend on muscle stem cells (MuSCs). Obstructive sleep apnea (OSA) rises in the aging population. OSA leads to hypoxia and upper airway muscle injury. However, l...

journal_title：Stem cells international

authors： Zhu LY,Yu LM,Zhang WH,Deng JJ,Liu SF,Huang W,Zhang MH,Lu YQ,Han XX,Liu YH

更新日期：2020-03-04 00:00:00

abstract：:Vitamin D (Vit D) by means of its biological active form, 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), has a protective effect on the skeleton by acting on calcium homeostasis and bone formation. Furthermore, Vit D has a direct effect on mesenchymal stem cells (MSCs) in stimulating their osteogenic differentiation. In thi...

journal_title：Stem cells international

authors： Posa F,Di Benedetto A,Cavalcanti-Adam EA,Colaianni G,Porro C,Trotta T,Brunetti G,Lo Muzio L,Grano M,Mori G

更新日期：2018-02-28 00:00:00

abstract：:Adipogenesis is the process through which preadipocytes differentiate into adipocytes. During this process, the preadipocytes cease to proliferate, begin to accumulate lipid droplets, and develop morphologic and biochemical characteristics of mature adipocytes. Mesenchymal stem cells (MSCs) are a type of adult stem ce...

journal_title：Stem cells international

authors： Zhang K,Yang X,Zhao Q,Li Z,Fu F,Zhang H,Zheng M,Zhang S

更新日期：2020-08-12 00:00:00

abstract：:The purpose of this study is to explore why type 2 diabetes mellitus (T2DM) patients are susceptible to pulmonary tuberculosis through detection of serum Toll-like receptor 4 (TLR4), an important immune-related receptor, especially in terms of content and TLR4 gene polymorphism. Patients with T2DM complicated by pulmo...

journal_title：Stem cells international

authors： Li Y,Li D,Zhang J,Liu S,Chen H,Wu K

更新日期：2016-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) derived from bone marrow can secrete cytokines and growth factors and can transdifferentiate into liver cells. We transplanted polymeric membrane bioencapsulated MSCs into the spleens of 90% partial hepatectomized rats. This resulted in 91.6% recovery rates. This is compared to a recovery...

journal_title：Stem cells international

authors： Liu ZC,Chang TM

更新日期：2012-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) possess immunosuppressive properties and have been described in the tumor microenvironment of glioblastoma multiforme (GBM). This manuscript has two major topics-first, to describe isolated and cultured MSCs derived from GBM (GB-MSCs) and second, to examine their in vitro immunosuppressiv...

journal_title：Stem cells international

authors： Tumangelova-Yuzeir K,Naydenov E,Ivanova-Todorova E,Krasimirova E,Vasilev G,Nachev S,Kyurkchiev D

更新日期：2019-05-02 00:00:00

abstract：Background:Cancer stem cell (CSC) promotes angiogenesis which plays an important role in tumor occurrence, growth, and metastasis. Accurately, quantifying the tumor vasculature can help understanding CSC characteristics and improve cancer diagnosis, therapy planning, and evaluation. The objective of this study is to pr...

journal_title：Stem cells international

authors： Zhang L,Zheng F,Peng Z,Hu Z,Yang Z

更新日期：2018-04-03 00:00:00

abstract：:This study evaluated the efficacy of mesenchymal stem cells (MSCs) from bone marrow of a third-party donor for refractory aGVHD. We report the first experience using MSCs to treat refractory aGVHD in 33 pediatric patients undergoing allogeneic HSCT from Turkey. Totally, 68 doses of bone marrow derived MSCs were infuse...

journal_title：Stem cells international

authors： Erbey F,Atay D,Akcay A,Ovali E,Ozturk G

更新日期：2016-01-01 00:00:00

abstract：Purpose:To determine the effect of the isolation technique and location upon the phenotype of human corneal stroma-derived cells (CSCs). Methods:CSCs were isolated from the corneal stroma center and periphery using the explant or enzymatic digestion technique. The native tissue was stained for functional markers, whil...

journal_title：Stem cells international

authors： Nagymihály R,Veréb Z,Facskó A,Moe MC,Petrovski G

更新日期：2017-01-01 00:00:00

abstract：:Coronary revascularization remains the standard treatment for obstructive coronary artery disease and can be accomplished by either percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery. Considerable advances have rendered PCI the most common form of revascularization and improved clinical o...

journal_title：Stem cells international

authors： Simard T,Jung RG,Motazedian P,Di Santo P,Ramirez FD,Russo JJ,Labinaz A,Yousef A,Anantharam B,Pourdjabbar A,Hibbert B

更新日期：2017-01-01 00:00:00

abstract：:A mere 9 years have passed since the revolutionary report describing the derivation of induced pluripotent stem cells from human fibroblasts and the first in-patient translational use of cells obtained from these stem cells has already been achieved. From the perspectives of clinicians and researchers alike, the promi...

journal_title：Stem cells international

authors： Gowran A,Rasponi M,Visone R,Nigro P,Perrucci GL,Righetti S,Zanobini M,Pompilio G

更新日期：2016-01-01 00:00:00

abstract：:Titanium (Ti) is widely used as a biomaterial for endosseous implants due to its relatively inert surface oxide layer that enables implanted devices the ability of assembling tissue reparative components that culminate in osseointegration. Topographic modifications in the form of micro- and nanoscaled structures signi...

journal_title：Stem cells international

authors： Khan MR,Mordan N,Parkar M,Salih V,Donos N,Brett PM

更新日期：2019-07-01 00:00:00