Effect of Chitosan Nanoparticle-Loaded Thymus serpyllum on Hydrogen Peroxide-Induced Bone Marrow Stromal Cell Damage.

abstract：:Mesenchymal stromal cells (MSCs) offering valuable anticipations for the treatment of degenerative diseases. They can be found in many tissues including amnion. MSCs from amnion (AM-MSCs) can differentiate into osteoblast similar to that of bone marrow-derived MSCs (BM-MSCs). However, the ability is not much efficient...

journal_title：Stem cells international

authors： Manochantr S,Marupanthorn K,Tantrawatpan C,Kheolamai P,Tantikanlayaporn D,Sanguanjit P

更新日期：2017-01-01 00:00:00

abstract：:Increasing the success rate of rotator cuff healing remains tremendous challenge. Among many approaches, the possibility of activating resident stem cells in situ, without the need to isolate them from biopsies, could represent valuable therapeutic strategy. Along this line, it has been recently demonstrated that lipo...

journal_title：Stem cells international

authors： Randelli P,Menon A,Ragone V,Creo P,Bergante S,Randelli F,De Girolamo L,Alfieri Montrasio U,Banfi G,Cabitza P,Tettamanti G,Anastasia L

更新日期：2016-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2015/496512.]. ...

journal_title：Stem cells international

authors： Sasi SP,Park D,Muralidharan S,Wage J,Kiladjian A,Onufrak J,Enderling H,Yan X,Goukassian DA

更新日期：2016-01-01 00:00:00

abstract：:Hematopoietic stem cell transplantation (HSCT) is one of a range of therapeutic options available to patients suffering from various diseases. HSCT procedure involves important ethical and legal aspects that can occur at every phase of the procedure: the clinical choice of whether to perform the procedure, pretranspla...

journal_title：Stem cells international

authors： Liso A,Neri M,Maglietta F,La Russa R,Turillazzi E

更新日期：2017-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into cells from the mesenchymal lineage. The hypoimmunogenic characteristic of MSCs has encouraged studies using allogeneic MSCs for the treatment of autoimmune diseases and inflammatory conditions. Promising preclinical results and the saf...

journal_title：Stem cells international

authors： Oliveira RL,Chagastelles PC,Sesterheim P,Pranke P

更新日期：2017-01-01 00:00:00

abstract：:Hindlimb ischemia is still a clinical problem with high morbidity and mortality. Patients suffer from consequent rest pain, ulcers, cool limbs, and even amputation. Angiogenesis is a promising target for the treatment of ischemic limbs, providing extra blood for the ischemic region. In the present study, we investigat...

journal_title：Stem cells international

authors： Yin C,Liang Y,Zhang J,Ruan G,Li Z,Pang R,Pan X

更新日期：2016-01-01 00:00:00

abstract：:We previously found that human amniotic mesenchymal stem cells (hAMSCs) in coculture with CF immortalised airway epithelial cells (CFBE41o- line, CFBE) on Transwell® filters acquired an epithelial phenotype and led to the expression of a mature and functional CFTR protein. In order to explore the role of gap junction-...

journal_title：Stem cells international

authors： Carbone A,Zefferino R,Beccia E,Casavola V,Castellani S,Di Gioia S,Giannone V,Seia M,Angiolillo A,Colombo C,Favia M,Conese M

更新日期：2018-01-11 00:00:00

abstract：:There are very few model systems which demonstrate hematopoiesis in vitro. Previously, we described unique splenic stromal cell lines which support the in vitro development of hematopoietic cells and particularly myeloid cells. Here, the 5G3 spleen stromal cell line has been investigated for capacity to support the di...

journal_title：Stem cells international

authors： Lim HK,Periasamy P,O'Neill HC

更新日期：2018-12-25 00:00:00

abstract：:Background. Human cardiac-derived progenitor cells (hCPCs) have shown promise in treating heart failure (HF) in adults. The purpose of this study was to describe derivation of hCPCs from pediatric patients with end-stage HF. Methods. At surgery, discarded right atrial tissues (hAA) were obtained from HF patients (n = ...

journal_title：Stem cells international

authors： Steele A,Boucek RJ Jr,Jacobs JP,Steele P,Asante-Korang A,Chamizo W,Steele J,Chai PJ,Quintessenza JA

更新日期：2012-01-01 00:00:00

abstract：:Purpose. The current study was set out to address the therapeutic efficacy of topically applied mesenchymal stem cells (MSCs) on dry eye syndrome (DES) induced by benzalkonium chloride (BAC) in rats. Methods. Rats were divided into two groups just after establishment of DES. Eye drops containing either bromodeoxyuridi...

journal_title：Stem cells international

authors： Beyazyıldız E,Pınarlı FA,Beyazyıldız O,Hekimoğlu ER,Acar U,Demir MN,Albayrak A,Kaymaz F,Sobacı G,Delibaşı T

更新日期：2014-01-01 00:00:00

abstract：:The Wnt signalling pathway plays a crucial role in the development of the nervous system. This signalling cascade is initiated upon binding of the secreted Wnt ligand to a member of the family of frizzled receptors. In the present study, we analysed the presence of frizzled-4 in the enteric nervous system of human inf...

journal_title：Stem cells international

authors： Nothelfer K,Obermayr F,Belz N,Reinartz E,Bareiss PM,Bühring HJ,Beschorner R,Just L

更新日期：2016-01-01 00:00:00

abstract：:Human liver stem cells (HLSCs) are a mesenchymal stromal cell-like population resident in the adult liver. Preclinical studies indicate that HLSCs could be a good candidate for cell therapy. The aim of the present study was to evaluate the immunogenicity and the immunomodulatory properties of HLSCs on T-lymphocytes, n...

journal_title：Stem cells international

authors： Bruno S,Grange C,Tapparo M,Pasquino C,Romagnoli R,Dametto E,Amoroso A,Tetta C,Camussi G

更新日期：2016-01-01 00:00:00

abstract：:Wnt signalling has been implicated in the regulation of stem cell self-renewal and differentiation; however, the majority of in vitro studies are carried out using monolayer 2D culture techniques. Here, we used mesenchymal stromal cell (MSC) EGFP reporter lines responsive to Wnt pathway activation in a 3D spheroid cul...

journal_title：Stem cells international

authors： Saleh F,Carstairs A,Etheridge SL,Genever P

更新日期：2016-01-01 00:00:00

abstract：:A growing body of evidence supports the argument that bone marrow-derived mesenchymal stem cells (MSCs) can differentiate into cardiomyocyte-like cells in an appropriate cellular environment, but the differentiation rate is low. A cocktail method was designed: we investigated the role of 5-azacytidine (5-aza), salvian...

journal_title：Stem cells international

authors： Gao Q,Guo M,Jiang X,Hu X,Wang Y,Fan Y

更新日期：2014-01-01 00:00:00

abstract：:Human eyelid adipose-derived stem cells (HEASCs) are a new source of autologous mesenchymal stem cells, which are derived from neuroectoderm and potentially applied in the tissue regeneration and cell therapies. Based on the prevalence of blepharoplasty in Asia and the availability of HEASCs, we investigated the effec...

journal_title：Stem cells international

authors： Zhang M,Wang Z,Zhao Y,Zhang L,Xu L,Cao L,He W

更新日期：2018-03-19 00:00:00

abstract：:Designing and providing a scaffold are very important for the cells in tissue engineering. Polybutylene succinate (PBS) has high potential as a scaffold for bone regeneration due to its capacity in cell proliferation and differentiation. Also, stem cells from 3rd molar tooth germs were favoured in this study due to th...

journal_title：Stem cells international

authors： Abay N,Gurel Pekozer G,Ramazanoglu M,Kose GT

更新日期：2016-01-01 00:00:00

abstract：:The CRISPR/Cas9 system provides a powerful method for the genetic manipulation of the mammalian genome, allowing knockout of individual genes as well as the generation of genome-wide knockout cell libraries for genetic screening. However, the diploid status of most mammalian cells restricts the application of CRISPR/C...

journal_title：Stem cells international

authors： Yin Z,Chen L

更新日期：2017-01-01 00:00:00

abstract：:In cholestatic liver diseases, impaired bile excretion disrupts lipid homeostasis. We investigated changes of lipid metabolism, including mitochondrial β-oxidation, in a rat model of bile duct ligation (BDL) in which chorionic plate-derived mesenchymal stem cells (CP-MSCs) were transplanted. Serum cholesterol level, w...

journal_title：Stem cells international

authors： Lee YB,Choi JH,Kim EN,Seok J,Lee HJ,Yoon JH,Kim GJ

更新日期：2017-01-01 00:00:00

abstract：:We aim to investigate the effects of adipose-derived stem cells (ASCs) transplantation on irradiation-induced skeletal muscle fibrosis. Sixty-four rabbits were randomly divided into ASCs group and PBS group followed by irradiation at unilateral hip with a single dose of 80 Gy. Nonirradiated side with normal skeletal m...

journal_title：Stem cells international

authors： Sun W,Ni X,Sun S,Cai L,Yu J,Wang J,Nie B,Sun Z,Ni X,Cao X

更新日期：2016-01-01 00:00:00

abstract：:A stably established population of mouse bone marrow stromal cells (BMSCs) with self-renewal and multilineage differentiation potential was expanded in vitro for more than 50 passages. These cells express high levels of mesenchymal stem cell markers and can be differentiated into adipogenic, chondrogenic, and osteogen...

journal_title：Stem cells international

authors： Yu L,Hong W,Yang H,Xia YY,Feng Z

更新日期：2020-12-24 00:00:00

abstract：:Two of the main problems of stem cell and regenerative medicine are the exit of pluripotency and differentiation to functional cells or tissues. The answer to these two problems holds great value in the clinical translation of stem cell as well as regenerative medicine research. Although piling researches have reveale...

journal_title：Stem cells international

authors： Yang B,Kuang J,Wu C,Zhou W,Zhu S,Jiang H,Zhai Z,Wu Y,Peng J,Liu N,Hu H,Ide NM,Chen R,Zhao M,Zhu P

更新日期：2020-02-03 00:00:00

abstract：:The mesenchymal stem cells (MSCs) are known as highly plastic stem cells and can differentiate into specialized tissues such as adipose tissue, osseous tissue, muscle tissue, and nervous tissue. The differentiation of mesenchymal stem cells is very important in regenerative medicine. Their differentiation process is r...

journal_title：Stem cells international

authors： Wang F,Li X,Li Z,Wang S,Fan J

更新日期：2020-08-01 00:00:00

abstract：:Infertility is a condition that occurs very frequently and understanding what defines normal fertility is crucial to helping patients. Causes of infertility are numerous and the treatment often does not lead to desired pregnancy especially when there is a lack of functional gametes. In humans, the primordial germ cell...

journal_title：Stem cells international

authors： Nikolic A,Volarevic V,Armstrong L,Lako M,Stojkovic M

更新日期：2016-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) play important roles in cell fate decisions. However, the miRNAs and their targets involved in the regulation of cardiac lineage specification are largely unexplored. Here, we report novel functions of miR-142-3p in the regulation of cardiomyocyte differentiation from mouse embryonic stem cells (mES...

journal_title：Stem cells international

authors： Chen ZY,Chen F,Cao N,Zhou ZW,Yang HT

更新日期：2017-01-01 00:00:00

abstract：:Cord blood transplantation (CBT) is an attractive alternative therapy in adult patients with advanced hematological malignancies in whom matched donors are unavailable. However, the risk of complications, especially infections, post-CBT increases the mortality rates in these patients. Although the incidence of acute a...

journal_title：Stem cells international

authors： Narimatsu H

更新日期：2011-01-01 00:00:00

abstract：:Pulmonary emphysema is a respiratory condition characterized by alveolar destruction that leads to airflow limitation and reduced lung function. Although with extensive research, the pathophysiology of emphysema is poorly understood and effective treatments are still missing. Evidence suggests that mesenchymal stem ce...

journal_title：Stem cells international

authors： Cappetta D,De Angelis A,Spaziano G,Tartaglione G,Piegari E,Esposito G,Ciuffreda LP,Liparulo A,Sgambato M,Russo TP,Rossi F,Berrino L,Urbanek K,D'Agostino B

更新日期：2018-03-14 00:00:00

abstract：:Intestinal stem cells are located at the base of the crypts and are surrounded by a complex structure called niche. This environment is composed mainly of epithelial cells and stroma which provides signals that govern cell maintenance, proliferation, and differentiation. Understanding how the niche regulates stem cell...

journal_title：Stem cells international

authors： Gjorevski N,Ordóñez-Morán P

更新日期：2017-01-01 00:00:00

abstract：:Myocardial infarction is a leading cause of death among all cardiovascular diseases. Cell therapies using a cell population enriched with endothelial progenitor cells (EPCs), expanded CD133+ cells, have promise as a therapeutic option for the treatment of ischemic areas after infarction. Recently, secreted membrane ve...

journal_title：Stem cells international

authors： Angulski ABB,Capriglione LGA,Barchiki F,Brofman P,Stimamiglio MA,Senegaglia AC,Correa A

更新日期：2019-12-01 00:00:00

abstract：:Background. The aim of the study was to assess the histological effects of autologous infusion of adipose-derived stem cells (ADSC) on a chronic vocal fold scar in a rabbit model as compared to an untreated scar as well as in injection of hyaluronic acid. Study Design. Animal experiment. Method. We used 74 New Zealand...

journal_title：Stem cells international

authors： Valerie A,Vassiliki K,Irini M,Nikolaos P,Karampela E,Apostolos P

更新日期：2016-01-01 00:00:00

abstract：:Current tissue engineering techniques are limited by inadequate vascularisation and perfusion of cell-scaffold constructs. Microstructural patterning through biomimetic vascular channels within a polymer scaffold might induce neovascularization, allowing fabrication of large engineered constructs. The network of vascu...

journal_title：Stem cells international

authors： Muller D,Chim H,Bader A,Whiteman M,Schantz JT

更新日期：2010-12-01 00:00:00