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Intracoronary pressure increase due to contrast injection for optical coherence tomography imaging.

Abstract：

BACKGROUND:Optical coherence tomography (OCT) requires intracoronary injection of contrast media to remove blood from the field of view during image acquisition. Contrast injection may cause a temporal increase in intracoronary pressure. The aim of this study was to compare the intracoronary pressure during contrast injection between OCT and coronary angiography. METHODS:We measured intracoronary pressure by using a pressure guidewire during contrast injection for OCT and angiography in 30 coronary arteries (mean fractional flow reserve = 0.90 ± 0.03). Contrast media was injected into coronary artery through the guiding catheter by using a mechanical injector pump. RESULTS:Intracoronary pressure before contrast injection was similar between OCT and angiography (systolic pressure: 123 ± 18 mmHg vs. 122 ± 19 mmHg, p = 0.863). Intracoronary pressure was increased due to contrast injection in both OCT (systolic pressure: 123 ± 18 mmHg to 132 ± 18 mmHg, p < 0.001) and angiography (systolic pressure: 122 ± 19 mmHg to 128 ± 19 mmHg, p < 0.001). The increase in intracoronary pressure was slightly greater in OCT compared with angiography (absolute increase of systolic pressure: 9 ± 2 mmHg vs. 6 ± 1 mmHg, p < 0.001; and relative increase of systolic pressure: 8 ± 2% vs. 5 ± 1%, p < 0.001). Intracoronary pressure during contrast injection was not significantly different between OCT and angiography (systolic pressure: 132 ± 18 mmHg vs. 128 ± 19 mmHg, p = 0.831). CONCLUSIONS:Contrast injection for OCT induced significant but small increase in intracoronary pressure compared with that for angiography.

journal_name

J Cardiol

journal_title

Journal of cardiology

authors

Shimamura K,Kubo T,Ino Y,Shiono Y,Matsuo Y,Kitabata H,Terada K,Emori H,Katayama Y,Khalifa AKM,Takahata M,Wada T,Higashioka D,Kashiwagi M,Kuroi A,Tanaka A,Hozumi T,Akasaka T

doi

10.1016/j.jjcc.2019.08.008

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

296-301

issue

3

eissn

0914-5087

issn

1876-4738

pii

S0914-5087(19)30267-9

journal_volume

75

pub_type

临床试验,杂志文章

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