Abstract:
BACKGROUND:Sarcopenia is one of the important predictors of heart failure (HF) in patients with cardiac problems. Skeletal muscle pump is important to maintain Fontan circulation. We aimed to quantify the volume of the psoas major muscle (PMM) and investigate whether it is relevant to HF hospitalization in adults with Fontan circulation. METHODS:A total of 154 adults with Fontan circulation, and 30 age-matched adults were studied retrospectively. We identified secondary sarcopenia by measuring the PMM volume, using non-contrast abdominal computed tomography. RESULTS:PMM indexed volume in Fontan patients was lower than controls (206.4+/-18.0 cc/m2 vs 288.0+/-61.1 cc/m2, p < 0.0001). In Fontan men, PMM indexed volume correlated with New York Heart Association functional class (NYHA FC). PMM indexed volume in Fontan women correlated with age, NYHA FC, and serum creatinine. Using a multivariate Cox hazards analysis, NYHA FC ≧3 was an important predictor of hospitalization due to HF in Fontan men. In Fontan women, NYHA FC ≧3, brain natriuretic peptide, PMM indexed volume, and protein losing enteropathy were important predictions of hospitalization due to HF. Among all Fontan patients, those with low PMM volumes had a poorer prognosis in HF [log rank p = 0.012 (men) and 0.0009 (women)]. CONCLUSIONS:PMM volume reduction has an adjunctive prediction of HF hospitalization in adults with Fontan circulation, particularly in Fontan females. Secondary sarcopenia may have a negative impact on the prognosis of HF in this population. The assessment of skeletal muscle mass also may be a comprehensive screening tool for multi-organ dysfunction in Fontan circulation.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Shiina Y,Nagao M,Shimomiya Y,Inai Kdoi
10.1016/j.jjcc.2020.06.009subject
Has Abstractpub_date
2021-01-01 00:00:00pages
10-16issue
1eissn
0914-5087issn
1876-4738pii
S0914-5087(20)30194-5journal_volume
77pub_type
杂志文章abstract::The usefulness of electrophysiologic study and Holter monitoring for predicting the long-term efficacy of amiodarone was investigated in 31 patients with sustained ventricular tachycardia (VT) and organic heart disease. Patients underwent both electrophysiologic study and Holter monitoring before and during oral admin...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Fabry disease is one of the causes of left ventricular hypertrophy (LVH) and can be treated with enzyme replacement therapy or pharmacological chaperone therapy. Late gadolinium enhancement (LGE) in cardiac magnetic resonance (CMR) can identify myocardial fibrosis and be used for the stratification in LVH. H...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.09.002
更新日期:2020-01-01 00:00:00
abstract::A 56-year-old man with old anteroseptal myocardial infarction was admitted to treat a gradually expanding coronary aneurysm. Coronary angiography demonstrated the aneurysm and delayed flow in the left coronary descending artery. The aneurysm was successfully treated with stenting. Technetium-99m-sestamibi single photo...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:To evaluate the left atrial (LA) volume and function of obese patients with/without obstructive sleep apnea (OSA) and its association with left ventricular (LV) diastolic function independent of obesity. METHODS:LA volumetric and functional parameters were measured by 2-dimensional and strain echocardiograp...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2012.07.007
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:The underlying cause of a high cardiovascular event rate in the population with low diastolic blood pressure (DBP) has not been fully elucidated. METHODS AND RESULTS:The relationship between DBP and ischemia-like findings on electrocardiography (ECG) was investigated in 187 patients who underwent coronary a...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2013.05.005
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:To assess the clinical significance of iodine-123 beta-methyl-p-iodophenyl-pentadecanoic acid(BMIPP) single photon emission computed tomography(SPECT), the predictive value of BMIPP imaging in patients with angina pectoris was evaluated. METHODS:One hundred seventy-four patients who underwent BMIPP imaging ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVES:Prediction of perioperative cardiac events associated with noncardiac surgery remains difficult in patients whose functional capacity cannot be evaluated by exercise testing. Dobutamine stress echocardiography (DSE) has been used in these patients to improve risk stratification, but the results of standard D...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::A histopathological study of coronary arteries in patients with acute coronary syndromes was carried out. The results of this study are as follows: 1. A high incidence of thrombus formation, corresponding to the site of the infarction, was observed in cases with acute myocardial infarction. 2. Coronary thrombi contain...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1999-03-01 00:00:00
abstract::Annuloaortic ectasia is often accompanied by Marfan syndrome and associated with infective endocarditis usually involving the mitral valves. We treated a patient with annuloaortic ectasia due to idiopathic cystic medial necrosis who developed congestive heart failure with aortic valvular vegetation. A 56-year-old man ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:To investigate the useful parameters of transthoracic echocardiography (TTE) for the diagnosis of stroke subtypes in patients with acute cerebral infarction. METHODS:One hundred and one acute ischemic stroke patients met all of the following criteria; > or = 50 years of age, normal sinus rhythm on admission...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Genetic regulation of plasma lipids has been shown to influence the risk of coronary artery disease (CAD). We analyzed the relationship between rs599839 and rs646776 single nucleotide polymorphisms (SNPs) present in the CELSR2-PSRC1-SORT1 gene cluster, candidate gene expression, and their association with CA...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2014.02.012
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:A better understanding of the epidemiology of pediatric out-of-hospital cardiac arrest (OHCA) occurring in nursery schools and kindergartens is indispensable to establish an evidence-based strategy for prevention and improved outcomes. This study aimed to describe the incidence, characteristics, and outcomes...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2020.06.003
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Predictors of left ventricular reverse remodeling (LVRR) and differences in the time taken to achieve LVRR remain unclear. METHODS:We consecutively registered 129 patients with severe cardiomyopathy admitted with heart failure (HF). Patients were followed for a median of 778.0 days (IQ: 457.0, 1078.0). LVRR...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2015.07.021
更新日期:2016-07-01 00:00:00
abstract::Inherited primary arrhythmia syndromes (IPAS) may result in ventricular tachycardia or ventricular fibrillation by some genetic disorders, leading to sudden cardiac death. IPAS are also called "channelopathies" since many of these are caused by an abnormality in myocardial ion channels. Congenital long-QT syndrome (LQ...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jjcc.2019.01.009
更新日期:2019-05-01 00:00:00
abstract::The floppy mitral valve prolapses into the left atrium in such a dynamic manner that the prolapsing floppy mitral valve becomes a space-occupying lesion within the left atrium. A significant result of the floppy mitral valve prolapsing into the left atrium during left ventricular systole is the development of a "third...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:
更新日期:2001-01-01 00:00:00
abstract::We evaluated the limits of recovery of decompensated hearts experimentally and clinically and studied the problems of applying a left ventricular assist device (LVAD). In the chronic experiments, 16 adult goats were studied as follows: Group I consisted of seven with left ventricular infarction in a 70-80% area of the...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::A 51-year-old man was admitted for evaluation of palpitation and syncope. Electrocardiography showed right bundle branch block with ST segment elevation. Intravenous administration of pilsicainide(50 mg) converted the saddle-back type into coved type ST elevation. Ventricular fibrillation was induced with double extra...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::Spontaneous coronary artery dissection (SCAD) is a rare condition that most often presents as acute coronary syndrome or sudden cardiac death. Here we present the case of a young man of 25 years, who had remained asymptomatic in spite of SCAD. This case highlights the fact that spontaneous dissections can occur at a y...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2009.03.007
更新日期:2009-12-01 00:00:00
abstract::Elevated levels of lipoprotein(a) [Lp(a)] have been associated with an increased risk of ischemic heart disease (IHD), and higher levels of Lp(a) are associated with lesions of significantly greater severity. We have examined Lp(a), total cholesterol (TC) and high density lipoprotein-cholesterol (HDL-C) levels in pati...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::A 83-year-old man was admitted because of heart failure due to severe aortic stenosis and mitral regurgitation secondary to chordal rupture of the anterior leaflet. Mild anemia and elevated serum lactate dehydrogenase were present with reticulocytosis and haptoglobinemia. Direct Coombs test was positive. Coexistence o...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVES:This study was designed to determine the prognostic importance of left ventricular (LV) myocardial stiffness, a hemodynamic index which is closely related to B-type natriuretic peptide (BNP) concentration in patients with congestive heart failure (CHF). BACKGROUND:While elevated BNP, an abnormality of cardi...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2011.07.005
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Myocardial fibrosis is the major factor that regulates left ventricular (LV) diastolic function. Pioglitazone, an anti-diabetic drug, is reported to improve the LV diastolic function in diabetic patients, but its influence on myocardial fibrosis has not been clarified. We evaluated the effect of pioglitazone...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2009.03.004
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Chronic renal disease (CKD) is a determinant of coronary artery calcification (CAC), which is a predictor of cardiovascular events. However, in a population without CKD, the association between CAC and renal function is unclear. CAC is affected by sex. This study aimed to determine whether serum cystatin C, ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2017.05.001
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVES:To investigate the quality of life (QOL) of Japanese patients with ischemic heart disease. METHODS:The QOL data of 753 patients with chronic and stable ischemic heart disease was assessed using SF-36 Japanese version 1.2 and compared with Japanese national norms. Physical (PCS) and Mental Component Summary ...
journal_title:Journal of cardiology
pub_type: 杂志文章,多中心研究
doi:
更新日期:2005-12-01 00:00:00
abstract::The treadmill exercise test (TET) is evaluated by exercise-induced ST-segment depression (delta ST). However, the depression sometimes only appears during the post-exercise period. Depression appearing only during the post-exercise period may be as useful as depression during exercise to predict coronary artery diseas...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:There are two types of circulating proprotein convertase subtilisin/kexin type 9 (PCSK9), mature and furin-cleaved. Most types of lipoprotein(a) [Lp(a)], an independent risk factor of cardiovascular events, bind to mature PCSK9. OBJECTIVE:This study examined the effects of monoclonal anti-PCSK9 antibody on ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2020.04.006
更新日期:2020-10-01 00:00:00
abstract::Whether beneficial hemodynamic effects of cardiovascular drugs are due to changes in the inotropic or loading conditions has been difficult to determine in clinical settings. In this study, the end-systolic pressure-volume relationship, known as a load-independent measurement of cardiac contractility, was obtained by ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::A 66-year-old man was admitted with distal edema of his right leg. He had undergone radical prostatectomy and pelvic lymphadenectomy for prostatic cancer 23 days previously. Abdominal computed tomography (CT) showed a lymphocyst (4.5 x 3.0 cm) along the right pelvic wall compressing the right external iliac vein. CT w...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Global coronary flow reserve (g-CFR) provides powerful prognostic information. The relationship between g-CFR and the regional physiological indices of fractional flow reserve (FFR), coronary flow reserve (r-CFR), and the index of microcirculatory resistance remains undetermined. This study aimed to assess t...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2018.12.005
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:This study evaluated the long-term outcomes of successfully implanted S670 and NIR stents. METHODS:Stents were successfully implanted in 143 patients (148 lesions) aged 65 +/- 9 years from January 1999 to April 2001. Sixty-eight lesions were treated with S670 stents and 80 with NIR stents. Quantitative coro...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2002-05-01 00:00:00