Evaluation of biochemical changes in dental tissues after different office bleaching methods.

abstract：:Dermal exposure is an important factor in risk characterization. In occupational settings it becomes relatively more important because of the continuous reduction in inhalation exposure. In the public health arena, dermal exposure may also form a significant contribution to the total exposure. Dermal exposure, however...

journal_title：Human & experimental toxicology

authors： Boogaard PJ

更新日期：2008-04-01 00:00:00

abstract：:1. Tobacco smoke contains around 4000 substances, most of which are described as toxic, and they may have an influence on the development of progeny. 2. The present studies concentrate on the measurement and calculation of indices describing the new-born's survival, rearing of pups, weight of foetuses, young animals, ...

journal_title：Human & experimental toxicology

authors： Florek E,Marszalek A,Biczysko W,Szymanowski K

更新日期：1999-04-01 00:00:00

abstract：:Phagocytes remove and store mercury (Hg) that enters the body. Macrophages and granulocytes respond in opposite ways to Hg: macrophages loose cell viability, and neutrophils become protected from apoptosis. We have investigated the cytology of early intake of Hg by macrophages and neutrophils after a short period (2-4...

journal_title：Human & experimental toxicology

authors： Cunha EM,Oliveira MJ,Ferreira PG,Aguas AP

更新日期：2004-08-01 00:00:00

abstract：:Male rats were exposed to manganese sulphate i.p. daily for a period of four weeks to see its effects on tissue levels and urinary excretion of total nicotinamide nucleotides (TNN). Increased levels of TNN were observed in blood and brain while the levels were found to be decreased in liver. There was a progressive in...

journal_title：Human & experimental toxicology

authors： Patel AB,Pandya AA

更新日期：1994-05-01 00:00:00

abstract：:Sodium hypochlorite (NaClO) is used extensively as a disinfectant or bleaching agent. Most studies describe ingestion or inhalation route of this product with rare complication and fatalities. Despite global daily exposures, data about bleach injection is limited. Here we report intentional infusion of 20 mL, sodium h...

journal_title：Human & experimental toxicology

authors： Rahmani SH,Ahmadi S,Vahdati SS,Moghaddam HH

更新日期：2012-06-01 00:00:00

abstract：:Pyrazinamide (PYZ)-an essential component of primary drug regimen used for the treatment and management of multidrug resistant or latent tuberculosis-is well known for its hepatoxicity. However, the mechanism of PYZ-induced hepatotoxicity is still unknown to researchers. Studies have shown that the drug is metabolized...

journal_title：Human & experimental toxicology

authors： Rawat A,Chaturvedi S,Singh AK,Guleria A,Dubey D,Keshari AK,Raj V,Rai A,Prakash A,Kumar U,Kumar D,Saha S

更新日期：2018-04-01 00:00:00

abstract：:It has been argued that the phenomenon of hormesis should prompt us to revise current regulatory policy in order to take beneficial effects of small doses of various agents into account. I argue that three problems--the comparative smallness of hormetic effects, the fine-tuning problem, and the problem of aggregated a...

journal_title：Human & experimental toxicology

authors： Sandin P

更新日期：2008-08-01 00:00:00

abstract：INTRODUCTION:Anthrax is a bacterial disease caused by the aerobic sporeforming bacterium Bacillus anthracis. It has been suggested that oxidative stress plays an important role in the pathogenesis of B. anthracis. The aim of this study was to investigate serum paraoxonase 1 (PON1) activity, catalase activity, malondial...

journal_title：Human & experimental toxicology

authors： Karadas S,Aslan M,Ceylan MR,Sunnetcioglu M,Bozan N,Kara H,Demir H

更新日期：2017-07-01 00:00:00

abstract：:Hexafluorocyclobutene (HFCB), a reactive organohalogen gas, causes overwhelming pulmonary oedema. We investigated its effect on the rat lung surfactant system, comparing its action on type II pneumocytes with air-exposed rats. The inflammatory cell population and protein content of bronchoalveolar lavage fluid was ana...

journal_title：Human & experimental toxicology

authors： Jugg B,Jenner J,Hughes JN,Rice P

更新日期：2001-05-01 00:00:00

abstract：:1. The effect of pyridostigmine on cardiorespiratory function after oxime + atropine injection was investigated in tabun poisoned guinea-pigs and without tabun poisoning. 2. The trachea, a carotid artery and jugular vein were cannulated in female urethane-anaesthetised Pirbright-white guinea-pigs. After baseline measu...

journal_title：Human & experimental toxicology

authors： Worek F,Kleine A,Szinicz L

更新日期：1995-08-01 00:00:00

abstract：:Arsenic trioxide (As2O3) is utilized for treating patients suffering from hematological malignancies particularly acute promyelocytic leukemia. Unfortunately, the extensive application of this chemotherapeutic agent has been limited due to its adverse effects such as cardiotoxicity. Ellagic acid, as a phenolic compoun...

journal_title：Human & experimental toxicology

authors： Hemmati AA,Olapour S,Varzi HN,Khodayar MJ,Dianat M,Mohammadian B,Yaghooti H

更新日期：2018-04-01 00:00:00

abstract：:The use of Lucilia sericata larvae on the healing of wounds in diabetics has been reported. However, the role of the excretion/secretion (ES) products of the larvae in treatment of diabetic wounds remains unknown. This study investigated whether application of the ES products of L. sericata on the wound surface could ...

journal_title：Human & experimental toxicology

authors： Tombulturk FK,Kasap M,Tuncdemir M,Polat E,Sirekbasan S,Kanli A,Kanigur-Sultuybek G

更新日期：2018-05-01 00:00:00

abstract：:The study was done to find out whether subacute exposure to supercypermethrin forte (SCM) affected cellular and humoral immunity. Groups of 10 male Wistar rats were given SCM by gavage for 28 days at 12.5 mg kg-1 day-1 (1/14 LD50), 8.75 mg kg-1 day-1 (1/20 LD50) and 4.38 mg kg-1 day-1 (1/40 LD50) and the response of s...

journal_title：Human & experimental toxicology

authors： Tulinská J,Kubová J,Janota S,Nyulassy S

更新日期：1995-05-01 00:00:00

abstract：:Sulfur dioxide (SO2) is a common exogenous atmospheric pollutant. Studies have shown that SO2 can cause vasodilation as a gas signaling molecule, but the specific signaling pathways are not well understood. This study aimed to explore the underlying mechanism behind the effects of SO2 on vasodilation of isolated rat a...

journal_title：Human & experimental toxicology

authors： Zhang Q,Lyu W,Yu M,Niu Y

更新日期：2020-08-01 00:00:00

abstract：:Potassium bromate (KBrO3) is a potent nephrotoxic agent. In this paper, we report the chemopreventive effect of Nigella sativa (black cumin) on KBrO3-mediated renal oxidative stress, toxicity and tumor promotion response in rats. KBrO3 (125 mg/kg body weight, intraperitoneally) enhances lipid peroxidation, gamma-gluta...

journal_title：Human & experimental toxicology

authors： Khan N,Sharma S,Sultana S

更新日期：2003-04-01 00:00:00

abstract：UNLABELLED:We present the first ever case of homicidal poisoning due to injection of methidathion, an organophosphate insecticide. CASE:A 4-month-old baby presented to the emergency department with chief complaints of unconsciousness and irregular respiration. A bitter odour and an injection site with a greenish blue ...

journal_title：Human & experimental toxicology

authors： Ozdemir C,Kar H,Bilge Y,Batuk G,Batuk HI

更新日期：2009-08-01 00:00:00

abstract：CONTEXT:Cardiac dysfunction is one of the most serious consequences of scorpion envenomation. The best tool to evaluate cardiac function is echocardiography, but it is not available at all emergency departments. Many studies aimed to describe biological predictive factors of cardiac dysfunction in scorpion envenomation...

journal_title：Human & experimental toxicology

authors： Chakroun-Walha O,Karray R,Jerbi M,Ben Rebeh A,Jammeli C,Bahloul M,Ammar R,Chabchoub I,Bouaziz M,Nasri A,Rekik N

更新日期：2018-06-01 00:00:00

abstract：:The malignancy of non-small cell lung cancer (NSCLC) largely results from its invasive manner. Secreted frizzled-related proteins (SFRPs) have been recently found to suppress the invasiveness of some cancers. On the other hand, the methylation of SFRPs increases protein degradation to reduce the activity of SFRPs, res...

journal_title：Human & experimental toxicology

authors： Zhang X,Rong X,Chen Y,Su L

更新日期：2018-02-01 00:00:00

abstract：:Brain tumors are often incurable despite current aggressive treatment modalities. Regional intracerebral administration of labeled monoclonal antibodies (Mabs) can maximize the radioisotope and Mab concentration to tumor sites while reducing systemic toxicity. h-R3 is a humanized antiepidermal growth factor receptor M...

journal_title：Human & experimental toxicology

authors： Gonzalez B,Casaco A,Alvarez P,Leon M,Arteaga M,Leon A,Santana E,Bada A,Figueredo R,Hernández R,Iznaga-Escobar N,González F,Perez R

更新日期：2000-12-01 00:00:00

abstract：:Periodontitis is a common infectious disease associated with destruction of periodontal ligaments and alveolar bones. CD4(+) T cell-mediated immune response is involved in the progression of periodontitis. Tobacco consumption increases the risk of periodontal disease. However, the impact of nicotine on the interaction...

journal_title：Human & experimental toxicology

authors： Ge X,Liu YF,Wong Y,Wu LZ,Tan L,Liu F,Wang XJ

更新日期：2016-09-01 00:00:00

abstract：:There is compelling evidence in support of positive associations between zinc (Zn) deficiency and high accumulation of cadmium (Cd) in biological samples of different cancerous patients. The incidence of mouth cancer has been increased among people who possess habit of drinking alcohol, tobacco smoking and chewing wit...

journal_title：Human & experimental toxicology

authors： Kazi TG,Wadhwa SK,Afridi HI,Kazi N,Kandhro GA,Baig JA,Shah AQ,Kolachi NF,Khan S

更新日期：2010-03-01 00:00:00

abstract：:The aim of this study was to investigate the possible protective role of caffeic acid phenethyl ester on testicular toxicity of methotrexate in rats. Nineteen male rats were divided into three groups as follows: group I, control; group II, methotrexate-treated; group III, methotrexate + caffeic acid phenethyl ester-tr...

journal_title：Human & experimental toxicology

authors： Armagan A,Uzar E,Uz E,Yilmaz HR,Kutluhan S,Koyuncuoglu HR,Soyupek S,Cam H,Serel TA

更新日期：2008-07-01 00:00:00

abstract：:This study was designed to determine the levels of prolactin, leptin, osteopontin, and follistatin in workers chronically and subacutely exposed to lead compounds. The examined population consisted of three groups. The first group was composed of 56 male workers who were chronically exposed to lead for 13.38 ± 10.38 y...

journal_title：Human & experimental toxicology

authors： Dobrakowski M,Kasperczyk A,Czuba ZP,Machoń-Grecka A,Szlacheta Z,Kasperczyk S

更新日期：2017-06-01 00:00:00

abstract：:The purpose of this study was to characterize the zinc oxide nanoparticles (ZnO-NPs) and their bulk counterpart in suspensions and to access the impact of their acute oral toxicity at doses of 300 and 2000 mg/kg in healthy female Wistar rats. The hematological, biochemical, and urine parameters were accessed at 24 and...

journal_title：Human & experimental toxicology

authors： Srivastav AK,Kumar M,Ansari NG,Jain AK,Shankar J,Arjaria N,Jagdale P,Singh D

更新日期：2016-12-01 00:00:00

abstract：:Many industrial and agricultural chemicals have steroid hormone agonist or antagonist activities and disrupt hormone-regulated gene expression. The widely-used agricultural insecticide, diazinon, was evaluated using MCF-7 cells - a breast cancer-derived, estrogen-dependent, human cell line - to examine the capacity of...

journal_title：Human & experimental toxicology

authors： Mankame T,Hokanson R,Fudge R,Chowdhary R,Busbee D

更新日期：2006-02-01 00:00:00

abstract：:The effects of acute administration of dietary levels of ethanol and the garlic oil extract, diallyl sulphide (DAS), on cytochrome P450 2E1 (CYP2E1) activity in volunteers were studied using the selective probe substrate, chlorzoxazone (CZX). The ratio of the CZX metabolite 6- hydroxychlorzoxazone (6-OHCZX) to CZX was...

journal_title：Human & experimental toxicology

authors： Loizou GD,Cocker J

更新日期：2001-07-01 00:00:00

abstract：:In order to assess the effect of arsenic on the male reproductive impairment in mice, 7-week-old animals were exposed to 7.5 mg sodium arsenite (NaAsO(2))/kg body weight, during 35 days (one spermatogenic cycle). One group of animals was sacrificed after exposure, while another group received distilled water for an ad...

journal_title：Human & experimental toxicology

authors： Ferreira M,Matos RC,Oliveira H,Nunes B,Pereira Mde L

更新日期：2012-03-01 00:00:00

abstract：:The effects of moderate lead exposure on testicular endocrine function were evaluated in a group of 90 males who were occupationally exposed to inorganic lead. Lead concentrations in blood and bone were measured as indices of short-term and long-term, cumulative exposure, respectively. The results of this study show t...

journal_title：Human & experimental toxicology

authors： McGregor AJ,Mason HJ

更新日期：1990-11-01 00:00:00

abstract：:Sulphur is an essential micronutrient required by the body in low concentrations, but its high intake can lead to a serious health hazard. Sulphur compounds are reported to induce several toxic responses in animals, but so far no reports are available on the toxic effects of elemental sulphur, following dietary supple...

journal_title：Human & experimental toxicology

authors： Arora A,Shukla Y

更新日期：2004-05-01 00:00:00

abstract：:Progesterone (a neurosteroid) is an important modulator of the nervous system functioning. Organophosphorus pesticides like phosphamidon have been shown to adversely affect memory and induce oxidative stress on both acute and chronic exposure. The present study was therefore designed to investigate the effects of prog...

journal_title：Human & experimental toxicology

authors： Sharma AK,Bhattacharya SK,Khanna N,Tripathi AK,Arora T,Mehta AK,Mehta KD,Joshi V

更新日期：2011-10-01 00:00:00