Letter--The Authors Respond.

abstract：:BACKGROUND: Nonadherence and nonpersistence to antidepressants in major depressive disorder (MDD) are common and associated with poor clinical and functional outcomes and increased health care resource utilization (HCRU) and costs. However, contemporary real-world evidence on the economic effect of antidepressant nona...

journal_title：Journal of managed care & specialty pharmacy

authors： Ta JT,Sullivan SD,Tung A,Oliveri D,Gillard P,Devine B

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Value-based insurance design (VBID) waives or reduces prescription copayments in order to decrease member cost barriers to refilling medications. Medication therapy management (MTM) is a member clinical intervention designed to reinforce members' knowledge of their medications, which addresses barriers to me...

journal_title：Journal of managed care & specialty pharmacy

authors： Peaslee A,Wickizer M,Olson J,Topp R

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Oral pharmacological treatment for overactive bladder (OAB) consists of antimuscarinics and the beta-3 adrenergic agonist mirabegron. Antimuscarinic adverse events (AEs) such as dry mouth, constipation, and blurry vision can result in frequent treatment discontinuation rates, leaving part of the OAB populati...

journal_title：Journal of managed care & specialty pharmacy

authors： Perk S,Wielage RC,Campbell NL,Klein TM,Perkins A,Posta LM,Yuran T,Klein RW,Ng DB

更新日期：2016-09-01 00:00:00

abstract：:The AMCP Abstracts program provides a forum through which authors can share their insights and outcomes of advanced managed care practice through publication in AMCP's Journal of Managed Care & Specialty Pharmacy (JMCP). Most of the reviewed and unreviewed abstracts are presented as posters so that interested AMCP mee...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:The approval of new oral disease-modifying drugs (DMDs), such as fingolimod, dimethyl fumarate (DMF), and teriflunamide, has considerably expanded treatment options for relapsing forms of multiple sclerosis (MS). However, data describing the use of these agents in routine clinical practice are limited. OBJE...

journal_title：Journal of managed care & specialty pharmacy

authors： Desai RJ,Mahesri M,Gagne JJ,Hurley E,Tong A,Chitnis T,Minden S,Spettell CM,Matlin OS,Shrank WH,Choudhry NK

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Clinical trials impose exclusion criteria that may limit the generalizability of results. OBJECTIVES:To (a) determine the percentage of real-world patients who would qualify for psoriasis randomized controlled trials; (b) ascertain differences between moderate-to-severe psoriasis patients who would be eligi...

journal_title：Journal of managed care & specialty pharmacy

authors： Malatestinic W,Nordstrom B,Wu JJ,Goldblum O,Solotkin K,Lin CY,Kistler K,Fraeman K,Johnston J,Hawley LL,Sicignano N,Araujo A

更新日期：2017-03-01 00:00:00

abstract：:A panel of experts drawn from neurology, psychiatry, geropsychiatry, geriatrics, and pharmacy representatives of 3 health plans convened in New York City on July 30, 2016, with the objective of sharing opinions, ideas, and information regarding the optimal management of Parkinson's disease psychosis (PDP). Three key p...

journal_title：Journal of managed care & specialty pharmacy

authors： Hermanowicz N,Alva G,Pagan F,Espay AJ,Patel A,Madrid KC,Kremens D,Kenney J,Arquette S,Tereso G,Lopes M,Farnum C

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The functional impairment associated with migraine can cause physical, emotional, and economic ramifications that can affect occupational, academic, social, and family life. Understanding the relationship between headache-free days (HFDs) and the disease burden of migraine may help with decisions regarding t...

journal_title：Journal of managed care & specialty pharmacy

authors： Lipton RB,Lee L,Saikali NP,Bell J,Cohen JM

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Despite multiple treatment options, the prognosis of pulmonary arterial hypertension (PAH) remains poor. PAH patients experience a high economic burden due to comorbidities, hospitalizations, and medication costs. Although combination therapy has been shown to reduce hospitalizations, the relationship betwee...

journal_title：Journal of managed care & specialty pharmacy

authors： Burger CD,Ozbay AB,Lazarus HM,Riehle E,Montejano LB,Lenhart G,White RJ

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The management of sickle cell disease (SCD), an inherited, chronic, and multifaceted condition, is associated with considerable health care resource utilization (HRU) and costs, especially for Medicaid. Anemia affects most patients with SCD and correlates with end-organ damage (EOD), such as stroke, chronic ...

journal_title：Journal of managed care & specialty pharmacy

authors： Campbell A,Cong Z,Agodoa I,Song X,Martinez DJ,Black D,Lew CR,Varker H,Chan C,Lanzkron S

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Poor medication adherence is a predictor of poor health outcomes, especially in populations with chronic diseases. Although several self-reported measures of medication adherence exist, the scope of each is limited.  OBJECTIVE:To identify barriers to medication adherence in order to facilitate effective del...

journal_title：Journal of managed care & specialty pharmacy

authors： Hincapie AL,Taylor AM,Boesen KP,Warholak T

更新日期：2015-05-01 00:00:00

abstract：:The ever-vulnerable medication supply chain is being further strained by the COVID-19 pandemic. Pharmacists in all settings, including managed care, will need to prepare for a potential exacerbation of existing and new drug shortages in the midst of unprecedented crisis. We summarize the major issues, discuss potentia...

journal_title：Journal of managed care & specialty pharmacy

authors： Shuman AG,Fox ER,Unguru Y

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Treatment patterns for metastatic colorectal cancer (mCRC) patients have changed considerably over the last decade with the introduction of new chemotherapies and targeted biologics. These treatments are often administered in various sequences with limited evidence regarding their cost-effectiveness. OBJECT...

journal_title：Journal of managed care & specialty pharmacy

authors： Parikh RC,Du XL,Robert MO,Lairson DR

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Diabetes is a leading cause of morbidity, mortality, and medical resource utilization in the United States and worldwide. Treatment is aimed at keeping blood glucose levels close to normal and preventing or delaying medical complications. It has been estimated that only 50% of patients with diabetes in the U...

journal_title：Journal of managed care & specialty pharmacy

authors： Saundankar V,Peng X,Fu H,Ascher-Svanum H,Rodriguez A,Ali A,Slabaugh L,Young P,Louder A

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The introduction of anti-vascular endothelial growth factor (anti-VEGF) drugs to ophthalmology has revolutionized the treatment of neovascular age-related macular degeneration (nAMD). Despite this significant progress, gaps and challenges persist in the diagnosis of nAMD, initiation of treatment, and managem...

journal_title：Journal of managed care & specialty pharmacy

authors： Wykoff CC,Clark WL,Nielsen JS,Brill JV,Greene LS,Heggen CL

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Adherence to biologic disease-modifying antirheumatic drugs (bDMARDs) among patients with rheumatoid arthritis (RA) is often suboptimal in routine clinical practice. Low or nonadherence can reduce the effectiveness of bDMARD therapies. OBJECTIVE:To evaluate filling of newly prescribed initial bDMARDs for th...

journal_title：Journal of managed care & specialty pharmacy

authors： Harnett J,Wiederkehr D,Gerber R,Gruben D,Bourret J,Koenig A

更新日期：2016-03-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this letter. Preblick, Ali, and DasMahapatra are employees and shareholders of Sanofi Genzyme. Gray is a postdoctoral fellow at Sanofi Genzyme and Rutgers University. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Preblick R,Gray C,Ali T,DasMahapatra P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The Biologics Price Competition and Innovation Act, introduced as part of the Affordable Care Act, directed the FDA to create an approval pathway for biologic products shown to be biosimilar or interchangeable with an FDA-approved innovator drug. These biosimilars will not be chemically identical to the refe...

journal_title：Journal of managed care & specialty pharmacy

authors： AMCP Task Force on Biosimilar Collective Intelligence Systems.,Baldziki M,Brown J,Chan H,Cheetham TC,Conn T,Daniel GW,Hendrickson M,Hilbrich L,Johnson A,Miller SB,Moore T,Motheral B,Priddy SA,Raebel MA,Randhawa G,Surratt

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES:To (a) assess how ACOs optimize ...

journal_title：Journal of managed care & specialty pharmacy

authors： Wilks C,Krisle E,Westrich K,Lunner K,Muhlestein D,Dubois R

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Nonadherence to medication regimens can lead to adverse health care outcomes and increasing costs. OBJECTIVES:To (a) assess the level of medication complexity at an outpatient setting using population-level electronic health record (EHR) data and (b) evaluate its association with medication adherence measur...

journal_title：Journal of managed care & specialty pharmacy

authors： Ma X,Jung C,Chang HY,Richards TM,Kharrazi H

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Encouraging generic drug use has reduced health care costs for payers and consumers, but the availability of therapeutically interchangeable medications or generic medications of choice is not equal across disease states. The extent to which systems of care are able to substitute with generics is not well un...

journal_title：Journal of managed care & specialty pharmacy

authors： Walton SM,Rash C,Lambert BL,Galanter WL

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Cancer is a major cause of mortality and a major contributor to health care costs in the United States. An increasing number of cancer patients are treated with oral cancer therapy. Older patients are more likely to have cancer and to be at risk for adherence problems with oral cancer drugs. As a result of s...

journal_title：Journal of managed care & specialty pharmacy

authors： Kaisaeng N,Harpe SE,Carroll NV

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Medication reconciliation is considered to be an important strategy for increasing the safety of medication use. However, few studies have been carried out showing the effect of a medication reconciliation program on the incidence of reconciliation errors (REs) in oncological patients treated in the outpatie...

journal_title：Journal of managed care & specialty pharmacy

authors： Vega TG,Sierra-Sánchez JF,Martínez-Bautista MJ,García-Martín F,Suárez-Carrascosa F,Baena-Cañada JM

更新日期：2016-06-01 00:00:00

abstract：:BACKGROUND: Measuring patient perspectives of the quality of health care delivery is an essential component of building a patient-centered model of care, which has garnered increasing emphasis under value-based payment models. Although measurements of patient perspectives of physician practices are common, few validat...

journal_title：Journal of managed care & specialty pharmacy

authors： Carpenter DM,Roberts CA,Farley JF

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:In 2013, it was reported that about 1 of every 3 U.S. adults has hypertension. Of these 70 million individuals, approximately 50% have their blood pressure under control. Achieving hypertension control, especially in at-risk populations, requires a multipronged approach that includes lifestyle modifications ...

journal_title：Journal of managed care & specialty pharmacy

authors： Lustig A,Ogden M,Brenner RW,Penso J,Westrich KD,Dubois RW

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Accurate estimates of the effects of cost sharing on adherence to medications prescribed for use together, also called concurrent adherence, are important for researchers, payers, and policymakers who want to reduce barriers to adherence for chronic condition patients prescribed multiple medications concurre...

journal_title：Journal of managed care & specialty pharmacy

authors： Sacks NC,Burgess JF,Cabral HJ,McDonnell ME,Pizer SD

更新日期：2015-08-01 00:00:00

abstract：DISCLOSURES:The author provides consulting services to the pharmaceutical industry, including manufacturers, health plans, employers, and specialty pharmacies, and is a member of the editorial advisory board of Specialty Pharmacy News. The author reports no financial or other conflicts of interest related to the subjec...

journal_title：Journal of managed care & specialty pharmacy

authors： Rubinstein E

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Discarding unused drugs after dose changes or discontinuation can significantly affect pharmacy budgets. This is especially concerning for expensive oncology agents. However, few economic studies account for drug wastage, providing an inaccurate estimate of a drug's actual economic cost, cost-effectiveness, ...

journal_title：Journal of managed care & specialty pharmacy

authors： Biskupiak J,Oderda G,Brixner D,Tang D,Zacker C,Dalal AA

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Allergy immunotherapy (AIT) is the only available treatment that alters the natural course of allergies and has possible disease-modifying effects. AIT is administered primarily via subcutaneous injection delivered in a physician's office. Few studies have been conducted in the United States or Canada to eva...

journal_title：Journal of managed care & specialty pharmacy

authors： Blume SW,Yeomans K,Allen-Ramey F,Smith N,Kim H,Lockey RF,Nichol MB

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:In recent years, there have been a number of pharmacological innovations for Crohn's disease (CD), a difficult-to-treat condition, including new treatment philosophies (e.g., top-down therapy) and new therapeutic options in terms of the agent and the route of administration. Three anti-tumor necrosis factor ...

journal_title：Journal of managed care & specialty pharmacy

authors： Liu J,Sylwestrzak G,Ruggieri AP,DeVries A

更新日期：2015-07-01 00:00:00