The Effectiveness and Value of Treatments for Spinal Muscular Atrophy.

abstract：BACKGROUND:Adherence to treatment is correlated with treatment success in chronic myeloid leukemia (CML). CVS Specialty explored novel methods to improve adherence in this population to ensure optimal adherence and lower the risk of unsuccessful treatment. One novel program explored involved an interactive 2-way clinic...

journal_title：Journal of managed care & specialty pharmacy

authors： Sawicki C,Friend KE,Patel R,Polinski JM,Singh S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Diabetes requires close monitoring to achieve optimal outcomes and avoid adverse effects. Continuous glucose monitoring (CGM) is one approach to measuring glycemia and has become more widespread with recent advances in technology; however, ideal implementation of CGM into clinical practice is unknown. CGM ca...

journal_title：Journal of managed care & specialty pharmacy

authors： Sherrill CH,Houpt CT,Dixon EM,Richter SJ

更新日期：2020-05-01 00:00:00

abstract：:Section 3002 of the 21st Century Cures Act, which was signed into law in December 2016, requires the FDA to develop one or more sets of new guidances regarding the collection of patient experience data. To explore how patient-reported outcomes (PROs) can support value-based care and discuss challenges to using PROs mo...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-03-21 00:00:00

abstract：:In a study published last year in the October 2014 issue of the Journal of Managed Care Specialty Pharmacy, Trivedi et al. compared treatment patterns of dasatinib and nilotinib as second-line tyrosine kinase inhibitors (TKI) therapy in chronic myeloid leukemia (CML) patients during the first year of treatment.1 Trive...

journal_title：Journal of managed care & specialty pharmacy

authors： Chen L,Wu EQ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Natalizumab disease-modifying therapy for relapsing-remitting multiple sclerosis (MS) is efficacious in randomized controlled trials. Few studies have estimated the association between real-world natalizumab persistence behavior and relapse-related outcomes. OBJECTIVES:To (a) examine the impact of using nat...

journal_title：Journal of managed care & specialty pharmacy

authors： McQueen RB,Livingston T,Vollmer T,Corboy J,Buckley B,Allen RR,Nair K,Campbell JD

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Concomitant use of stimulants and atypical antipsychotics is common in pediatric attention deficit hyperactivity disorder (ADHD). However, little is known about the determinants of concomitant use and its utility in the management of pediatric ADHD. OBJECTIVES:To (a) examine predictors of concomitant stimul...

journal_title：Journal of managed care & specialty pharmacy

authors： Bali V,Kamble PS,Aparasu RR

更新日期：2015-06-01 00:00:00

abstract：:Improving medication adherence has been identified as a crucial step towards improving health outcomes for patients with chronic disease and has provided the motivation for many changes in our health care system. Despite the volume of research done on this topic, however, we still lack important basic information abou...

journal_title：Journal of managed care & specialty pharmacy

authors： Seabury SA,Gupta CN,Philipson TJ,Henkhaus LE,PhRMA Medication Adherence Advisory Council.

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic, hyper-proliferative dermatological condition associated with joint symptoms known as psoriatic arthritis (PsA). In a 2013 review, the total economic burden of PsA was estimated at $51.7-$63.2 billion. The economic burden of moderate to severe psoriasis patients has reduced significant...

journal_title：Journal of managed care & specialty pharmacy

authors： Lee S,Xie L,Wang Y,Vaidya N,Baser O

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES:To (a) assess how ACOs optimize ...

journal_title：Journal of managed care & specialty pharmacy

authors： Wilks C,Krisle E,Westrich K,Lunner K,Muhlestein D,Dubois R

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:In recent years, there have been a number of pharmacological innovations for Crohn's disease (CD), a difficult-to-treat condition, including new treatment philosophies (e.g., top-down therapy) and new therapeutic options in terms of the agent and the route of administration. Three anti-tumor necrosis factor ...

journal_title：Journal of managed care & specialty pharmacy

authors： Liu J,Sylwestrzak G,Ruggieri AP,DeVries A

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Recent clinical trials indicate that pharmacogenetic-guided treatment of major depressive disorder (MDD) results in higher treatment response rates by genetically matching patients to medications and avoiding a trial-and-error process. OBJECTIVE:To evaluate the cost-effectiveness of a pharmacogenetic test (...

journal_title：Journal of managed care & specialty pharmacy

authors： Groessl EJ,Tally SR,Hillery N,Maciel A,Garces JA

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Prescription opioid abuse is associated with substantial economic burden, with estimates of incremental annual per-patient health care costs of diagnosed opioid abuse exceeding $10,000 in prior literature. A subset of patients diagnosed with opioid abuse has disproportionately high health care costs, but lit...

journal_title：Journal of managed care & specialty pharmacy

authors： Shei A,Rice JB,Kirson NY,Bodnar K,Enloe CJ,Birnbaum HG,Holly P,Ben-Joseph R

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Encouraging generic drug use has reduced health care costs for payers and consumers, but the availability of therapeutically interchangeable medications or generic medications of choice is not equal across disease states. The extent to which systems of care are able to substitute with generics is not well un...

journal_title：Journal of managed care & specialty pharmacy

authors： Walton SM,Rash C,Lambert BL,Galanter WL

更新日期：2014-11-01 00:00:00

abstract：DISCLOSURES:No funding contributed to the writing of this commentary. Brandsema reports consulting for Alexion, Audentes, AveXis, Biogen, Cytokinetics, PTC Therapeutics, Sarepta, and WaVe and has received research funding as a site investigator from Alexion, AveXis, Biogen, CSL Behring, Cytokinetics, Fibrogen, Pfizer, ...

journal_title：Journal of managed care & specialty pharmacy

authors： Brandsema JF

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) are a mainstay of treatment for patients suffering from chronic myeloid leukemia (CML). Testing for various mutations in the BCR-ABL gene may help predict lack of response to specific TKIs where resistance has developed. OBJECTIVE:To estimate the emergence of BCR-ABL kinase...

journal_title：Journal of managed care & specialty pharmacy

authors： Ursan ID,Jiang R,Pickard EM,Lee TA,Ng D,Pickard AS

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Gout, hyperuricemia, and cardiovascular disease (CVD) are prevalent conditions in the United States, and while they share common risk factors such as obesity, hypertension, hypercholesterolemia, and type 2 diabetes mellitus, relatively little is known about what patient and disease characteristics may link C...

journal_title：Journal of managed care & specialty pharmacy

authors： Pillinger MH,Bangalore S,Klein AB,Baumgartner S,Morlock R

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Tisagenlecleucel was approved for the treatment of pediatric and young adult patients with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (ALL) based on the pivotal ELIANA trial. OBJECTIVE:To comprehensively evaluate the total costs associated with tisagenlecleucel treatment, including costs ...

journal_title：Journal of managed care & specialty pharmacy

authors： Yang H,Hao Y,Qi CZ,Chai X,Wu EQ

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Employers have increased efforts to engage employees in health and wellness programs. Providing employees with incentives to participate in these programs has been shown to improve overall enrollment and engagement. One program that has had challenges with enrollment and engagement is medication therapy mana...

journal_title：Journal of managed care & specialty pharmacy

authors： Tomaszewski D,Cernohous T,Vaidyanathan R

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:This study is an evaluation of a discharge intervention that occurred in multiple hospitals across Maryland. In this program, patients received medications at their bedside before discharge with the goal of reducing the risk of primary nonadherence to prescribed medications. OBJECTIVE:To test if the interve...

journal_title：Journal of managed care & specialty pharmacy

authors： Segal JB,Apfel A,Brotman DJ,Shermock KM,Clark JM

更新日期：2020-03-01 00:00:00

abstract：:The inclusion of pharmacists on care teams has been shown to improve clinical and economic health outcomes. However, a significant barrier to the widespread incorporation of pharmacists into care teams is the ability to financially support the salary of the pharmacist. A mechanism to improve the ability of pharmacists...

journal_title：Journal of managed care & specialty pharmacy

authors： Dietrich E,Gums JG

更新日期：2018-12-01 00:00:00

abstract：DISCLOSURES:No funding was required for this project. The authors are or have been members of the Format Executive Committee. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Watkins JB,Sullivan SD,Sampsel E,Fullerton DSP,Graff JS,Fry RN,Lee J,Tam IM,Avey SG

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Three pharmacist-specific Current Procedural Terminology (CPT) codes exist to facilitate medication therapy management (MTM) reimbursement (codes 99605, 99606, and 99607). However, no studies have used CPT codes in administrative claims databases to identify subjects who have received MTM services. OBJECTIV...

journal_title：Journal of managed care & specialty pharmacy

authors： Axon DR,Chinthammit C,Tate J,Taylor AM,Leal S,Pickering M,Black H,Warholak T,Campbell PJ

更新日期：2020-10-01 00:00:00

abstract：DISCLOSURES:No additional funding was received for the writing of this letter. The published study referred to in this letter was funded by Janssen Scientific Affairs, which employs Maiese and funded Cornerstone Research Group, a health economic consulting group, to conduct the study. Grima is a founding partner of Cor...

journal_title：Journal of managed care & specialty pharmacy

authors： Hollmann S,Moldaver D,Goyert N,Grima D,Maiese EM

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Current evidence of the effects of pharmacy services on asthma outcomes are not conclusive, since most pharmacy services comprise a variety of interventions. OBJECTIVE:To assess the effect of a service containing self-management support delivered by community pharmacists to patients with asthma. METHODS:A ...

journal_title：Journal of managed care & specialty pharmacy

authors： Dokbua S,Dilokthornsakul P,Chaiyakunapruk N,Saini B,Krass I,Dhippayom T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Adherence to biologic disease-modifying antirheumatic drugs (bDMARDs) among patients with rheumatoid arthritis (RA) is often suboptimal in routine clinical practice. Low or nonadherence can reduce the effectiveness of bDMARD therapies. OBJECTIVE:To evaluate filling of newly prescribed initial bDMARDs for th...

journal_title：Journal of managed care & specialty pharmacy

authors： Harnett J,Wiederkehr D,Gerber R,Gruben D,Bourret J,Koenig A

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The introduction of anti-vascular endothelial growth factor (anti-VEGF) drugs to ophthalmology has revolutionized the treatment of neovascular age-related macular degeneration (nAMD). Despite this significant progress, gaps and challenges persist in the diagnosis of nAMD, initiation of treatment, and managem...

journal_title：Journal of managed care & specialty pharmacy

authors： Wykoff CC,Clark WL,Nielsen JS,Brill JV,Greene LS,Heggen CL

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Clinical pharmacy services were initiated at 7 of 11 clinics within a primary care network (PCN), which was designated as a patient-centered medical home and was affiliated with a large academic medical center in October 2014. The goal of the service was to target patients with uncontrolled chronic condition...

journal_title：Journal of managed care & specialty pharmacy

authors： Prudencio J,Cutler T,Roberts S,Marin S,Wilson M

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Cancer is a major cause of mortality and a major contributor to health care costs in the United States. An increasing number of cancer patients are treated with oral cancer therapy. Older patients are more likely to have cancer and to be at risk for adherence problems with oral cancer drugs. As a result of s...

journal_title：Journal of managed care & specialty pharmacy

authors： Kaisaeng N,Harpe SE,Carroll NV

更新日期：2014-07-01 00:00:00

abstract：DISCLOSURES:No outside funding supported the writing of this letter. Farley has received funding from the National Community Pharmacy Association for previous research. Schondelmeyer advises the University of Minnesota Health Benefit plan on its prescription drug coverage. Urick has received a grant from Cardinal Healt...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:While there is growing demand for information about comparative effectiveness (CE), there is substantial debate about whether and when observational studies have sufficient quality to support decision making. OBJECTIVE:To develop and test an item checklist that can be used to qualify those observational CE ...

journal_title：Journal of managed care & specialty pharmacy

authors： Dreyer NA,Velentgas P,Westrich K,Dubois R

更新日期：2014-03-01 00:00:00