Adherence and Persistence Among Chronic Myeloid Leukemia Patients During Second-Line Tyrosine Kinase Inhibitor Treatment.

abstract：:Improving medication adherence has been identified as a crucial step towards improving health outcomes for patients with chronic disease and has provided the motivation for many changes in our health care system. Despite the volume of research done on this topic, however, we still lack important basic information abou...

journal_title：Journal of managed care & specialty pharmacy

authors： Seabury SA,Gupta CN,Philipson TJ,Henkhaus LE,PhRMA Medication Adherence Advisory Council.

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Encouraging generic drug use has reduced health care costs for payers and consumers, but the availability of therapeutically interchangeable medications or generic medications of choice is not equal across disease states. The extent to which systems of care are able to substitute with generics is not well un...

journal_title：Journal of managed care & specialty pharmacy

authors： Walton SM,Rash C,Lambert BL,Galanter WL

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Costs associated with biologic switching and discontinuation can be high in chronic inflammatory diseases. Inappropriate use of medications may have cost implications for both payers and patients. Understanding of biologic utilization and switching rates is lacking among patients with ankylosing spondylitis ...

journal_title：Journal of managed care & specialty pharmacy

authors： Yi E,Dai D,Piao OW,Zheng JZ,Park Y

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Previous research finds significant variation in spending and utilization across regions, with little evidence of differences in outcomes. While such findings have been interpreted as evidence that spending can be reduced without compromising patient outcomes, the link between spending variation and outcomes...

journal_title：Journal of managed care & specialty pharmacy

authors： Baumgardner J,Shahabi A,Linthicum M,Vine S,Zacker C,Lakdawalla D

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Treatment patterns for metastatic colorectal cancer (mCRC) patients have changed considerably over the last decade with the introduction of new chemotherapies and targeted biologics. These treatments are often administered in various sequences with limited evidence regarding their cost-effectiveness. OBJECT...

journal_title：Journal of managed care & specialty pharmacy

authors： Parikh RC,Du XL,Robert MO,Lairson DR

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Recent evidence has demonstrated that, over 12 months, pharmacy costs associated with switching nonadherent recently relapsed patients from oral atypical antipsychotics (OAAs) to once-monthly paliperidone palmitate (PP1M) were offset by reduced relapse rates and schizophrenia-related health care costs. In ad...

journal_title：Journal of managed care & specialty pharmacy

authors： El Khoury AC,Pilon D,Morrison L,Shak N,Llaneza A,Kim E,Lefebvre P

更新日期：2020-02-01 00:00:00

abstract：:Section 3002 of the 21st Century Cures Act, which was signed into law in December 2016, requires the FDA to develop one or more sets of new guidances regarding the collection of patient experience data. To explore how patient-reported outcomes (PROs) can support value-based care and discuss challenges to using PROs mo...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:Lipid screening determines eligibility for statins and other cardiovascular risk reduction interventions. OBJECTIVE:To examine trends in lipid screening among adults aged ≥20 years in a large, multiethnic, integrated health care delivery system in southern California. METHODS:Temporal trends in lipid scree...

journal_title：Journal of managed care & specialty pharmacy

authors： Grant DSL,Scott RD,Harrison TN,Cheetham TC,Chang SC,Hsu JY,Wei R,Boklage SH,Romo-LeTourneau V,Reynolds K

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is associated with substantial morbidity and mortality. With the rise in prevalence of diabetes, there has been an increased need for clinical pharmacy services focused on diabetes management in ambulatory clinics. However, more data IS needed to determine the overall impact that clinical p...

journal_title：Journal of managed care & specialty pharmacy

authors： Chung N,Rascati K,Lopez D,Jokerst J,Garza A

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Discarding unused drugs after dose changes or discontinuation can significantly affect pharmacy budgets. This is especially concerning for expensive oncology agents. However, few economic studies account for drug wastage, providing an inaccurate estimate of a drug's actual economic cost, cost-effectiveness, ...

journal_title：Journal of managed care & specialty pharmacy

authors： Biskupiak J,Oderda G,Brixner D,Tang D,Zacker C,Dalal AA

更新日期：2019-08-01 00:00:00

abstract：:DISCLOSURES: Funding for the study referred to in this letter was contributed by Bayer Healthcare. Xia and Williamson are employees of Bayer Healthcare. Roth, Carlson, and Sullivan are consultants to Bayer Healthcare. Carlson also reports fees from Adaptive Biotechnologies, unrelated to the study. Roth reports consult...

journal_title：Journal of managed care & specialty pharmacy

authors： Roth JA,Carlson JJ,Xia F,Williamson T,Sullivan SD

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Employers have increased efforts to engage employees in health and wellness programs. Providing employees with incentives to participate in these programs has been shown to improve overall enrollment and engagement. One program that has had challenges with enrollment and engagement is medication therapy mana...

journal_title：Journal of managed care & specialty pharmacy

authors： Tomaszewski D,Cernohous T,Vaidyanathan R

更新日期：2017-11-01 00:00:00

abstract：DISCLOSURES:No funding was involved in the writing of this letter. Outside of the submitted work, Hiligsmann has received research grants through institution from Amgen, Radius Health, UCB, and Teva/Theramex. Reginster has received research grants and/or consulting fees from Servier, Novartis, Negma, Lilly, Wyeth, Amge...

journal_title：Journal of managed care & specialty pharmacy

authors： Hiligsmann M,Reginster JY,Silverman S

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:All Department of Veterans Affairs Medical Centers (VAMCs) operate under a single national drug formulary, yet substantial variation in prescribing and spending exists across facilities. Local management of the national formulary may differ across VAMCs and may be one cause of this variation. OBJECTIVE:To c...

journal_title：Journal of managed care & specialty pharmacy

authors： Radomski TR,Good CB,Thorpe CT,Zhao X,Marcum ZA,Glassman PA,Lowe J,Mor MK,Fine MJ,Gellad WF

更新日期：2016-02-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this article. The author has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Lever HM

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Nearly half of statin users discontinue therapy within the first year of treatment. Nonadherence to statin therapy may lead to an increased risk of atherosclerotic cardiovascular disease and, thus, higher costs due to hospitalizations. Value-based care models, such as accountable care organizations (ACO), ar...

journal_title：Journal of managed care & specialty pharmacy

authors： Tamargo C,Sando K,Prados Y,Cowart K

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Formulary or preferred drug list (PDL) management is an effective strategy to ensure clinically efficient prescription drug management by managed care organizations (MCOs). Medicaid MCOs participating in Florida's Medicaid program were required to use a state-mandated PDL between May and August 2014. OBJECT...

journal_title：Journal of managed care & specialty pharmacy

authors： Munshi KD,Mager D,Ward KM,Mischel B,Henderson RR

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The management of schizophrenia, a chronic, multifaceted mental health condition, is associated with considerable health care resource utilization (HCRU) and costs. Current evidence indicates that a high-risk and costly prodromal period, during which patients are likely symptomatic, precedes diagnosis. Bette...

journal_title：Journal of managed care & specialty pharmacy

authors： Wallace A,Barron J,York W,Isenberg K,Franchino-Elder J,Sidovar M,Sand M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The approval of new oral disease-modifying drugs (DMDs), such as fingolimod, dimethyl fumarate (DMF), and teriflunamide, has considerably expanded treatment options for relapsing forms of multiple sclerosis (MS). However, data describing the use of these agents in routine clinical practice are limited. OBJE...

journal_title：Journal of managed care & specialty pharmacy

authors： Desai RJ,Mahesri M,Gagne JJ,Hurley E,Tong A,Chitnis T,Minden S,Spettell CM,Matlin OS,Shrank WH,Choudhry NK

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Geographic variation in the use of prescription drugs, particularly those deemed harmful by the FDA, may lead to variation in patient exposure to adverse drug events. One such drug is the glucose-lowering drug rosiglitazone, for which the FDA issued a safety alert on May 21, 2007, following the publication o...

journal_title：Journal of managed care & specialty pharmacy

authors： Ahuja V,Sohn MW,Birge JR,Syverson C,Budiman-Mak E,Emanuele N,Cooper JM,Huang ES

更新日期：2015-12-01 00:00:00

abstract：DISCLOSURES:No outside funding supported the writing of this letter. Farley has received funding from the National Community Pharmacy Association for previous research. Schondelmeyer advises the University of Minnesota Health Benefit plan on its prescription drug coverage. Urick has received a grant from Cardinal Healt...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Adherence to adjuvant endocrine therapy (AET) for estrogen receptor-positive breast cancer remains suboptimal, which suggests that women are not getting the full benefit of the treatment to reduce breast cancer recurrence and mortality. The majority of studies on adherence to AET focus on identifying factors...

journal_title：Journal of managed care & specialty pharmacy

authors： Farias AJ,Hansen RN,Zeliadt SB,Ornelas IJ,Li CI,Thompson B

更新日期：2016-08-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this letter. Preblick, Ali, and DasMahapatra are employees and shareholders of Sanofi Genzyme. Gray is a postdoctoral fellow at Sanofi Genzyme and Rutgers University. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Preblick R,Gray C,Ali T,DasMahapatra P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Diabetes is a leading cause of morbidity, mortality, and medical resource utilization in the United States and worldwide. Treatment is aimed at keeping blood glucose levels close to normal and preventing or delaying medical complications. It has been estimated that only 50% of patients with diabetes in the U...

journal_title：Journal of managed care & specialty pharmacy

authors： Saundankar V,Peng X,Fu H,Ascher-Svanum H,Rodriguez A,Ali A,Slabaugh L,Young P,Louder A

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Diabetes requires close monitoring to achieve optimal outcomes and avoid adverse effects. Continuous glucose monitoring (CGM) is one approach to measuring glycemia and has become more widespread with recent advances in technology; however, ideal implementation of CGM into clinical practice is unknown. CGM ca...

journal_title：Journal of managed care & specialty pharmacy

authors： Sherrill CH,Houpt CT,Dixon EM,Richter SJ

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Prostacyclins play an important role in the management of pulmonary arterial hypertension (PAH). Intravenous prostacyclin was the first disease-specific treatment for patients with PAH. Subcutaneous and nonparenteral (oral or inhaled) formulations have subsequently become available. However, data are lacking...

journal_title：Journal of managed care & specialty pharmacy

authors： Burger CD,Pruett JA,Lickert CA,Berger A,Murphy B,Drake W 3rd

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Adherence to antiretrovirals (ARVs) is critical to achieving durable virologic suppression. OBJECTIVE:To investigate risk factors of poor adherence and the effect of suboptimal adherence on health care resource utilization (HCRU) and costs in Medicaid patients. METHODS:A retrospective longitudinal study wa...

journal_title：Journal of managed care & specialty pharmacy

authors： Dunn K,Lafeuille MH,Jiao X,Romdhani H,Emond B,Woodruff K,Pesa J,Tandon N,Lefebvre P

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The implementation of Medicare Part D provided insurance coverage for outpatient medications, but when persons reach the "gap," they have very limited or no medication insurance coverage until they reach a second threshold for catastrophic coverage. In addition, some patients have a low-income subsidy (LIS),...

journal_title：Journal of managed care & specialty pharmacy

authors： Park H,Rascati KL,Lawson KA,Barner JC,Richards KM,Malone DC

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Adjuvant trastuzumab treatment is administered to early stage breast cancer patients in physician office (POV) or hospital outpatient (HOP) settings. OBJECTIVE:To identify treatment patterns, utilization, and costs by site of care (POV vs. HOP) of patients with adjuvant treatment of breast cancer with trast...

journal_title：Journal of managed care & specialty pharmacy

authors： Parthan A,Santos E,Becker L,Small A,Lalla D,Brammer M,Teitelbaum A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Immunoglobulin (Ig) is a costly blood product prescribed as immune replacement or modulation therapy to treat a wide spectrum of medical conditions. While the FDA has approved Ig for a limited number of indications, there are multiple off-label uses that have demonstrated proven clinical benefit or are curre...

journal_title：Journal of managed care & specialty pharmacy

authors： Tonkovic B,Rutishauser LK

更新日期：2014-04-01 00:00:00