Understanding and overcoming barriers to medication adherence: a review of research priorities.

abstract：BACKGROUND:The management of schizophrenia, a chronic, multifaceted mental health condition, is associated with considerable health care resource utilization (HCRU) and costs. Current evidence indicates that a high-risk and costly prodromal period, during which patients are likely symptomatic, precedes diagnosis. Bette...

journal_title：Journal of managed care & specialty pharmacy

authors： Wallace A,Barron J,York W,Isenberg K,Franchino-Elder J,Sidovar M,Sand M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Since multiple myeloma (MM) incurs a substantial economic burden in care management, more and more discussion has been generated in recent years about the costs of novel antimyeloma drugs and their associated value. Because of these costs, economic assessment that quantifies value of care over the long-term ...

journal_title：Journal of managed care & specialty pharmacy

authors： Chen Y,Lairson DR,Chan W,Huo J,Du XL

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Immunoglobulin (Ig) is a costly blood product prescribed as immune replacement or modulation therapy to treat a wide spectrum of medical conditions. While the FDA has approved Ig for a limited number of indications, there are multiple off-label uses that have demonstrated proven clinical benefit or are curre...

journal_title：Journal of managed care & specialty pharmacy

authors： Tonkovic B,Rutishauser LK

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:In recent years, there have been a number of pharmacological innovations for Crohn's disease (CD), a difficult-to-treat condition, including new treatment philosophies (e.g., top-down therapy) and new therapeutic options in terms of the agent and the route of administration. Three anti-tumor necrosis factor ...

journal_title：Journal of managed care & specialty pharmacy

authors： Liu J,Sylwestrzak G,Ruggieri AP,DeVries A

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The approval of new oral disease-modifying drugs (DMDs), such as fingolimod, dimethyl fumarate (DMF), and teriflunamide, has considerably expanded treatment options for relapsing forms of multiple sclerosis (MS). However, data describing the use of these agents in routine clinical practice are limited. OBJE...

journal_title：Journal of managed care & specialty pharmacy

authors： Desai RJ,Mahesri M,Gagne JJ,Hurley E,Tong A,Chitnis T,Minden S,Spettell CM,Matlin OS,Shrank WH,Choudhry NK

更新日期：2019-01-01 00:00:00

abstract：:The AMCP Abstracts program provides a forum through which authors can share their insights and outcomes of advanced managed care practice through publication in AMCP's Journal of Managed Care & Specialty Pharmacy (JMCP). Most of the reviewed and unreviewed abstracts are presented as posters so that interested AMCP mee...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2016-04-01 00:00:00

abstract：UNLABELLED:Medication adherence is a problem that has received widespread attention in the medical literature and health policy circles. With the increased emphasis on recognizing and rewarding quality in the U.S. health care system, medication adherence measures are increasingly being adopted to assess quality of medi...

journal_title：Journal of managed care & specialty pharmacy

authors： Sorensen TD,Pestka DL,Brummel AR,Rehrauer DJ,Ekstrand MJ

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Natalizumab disease-modifying therapy for relapsing-remitting multiple sclerosis (MS) is efficacious in randomized controlled trials. Few studies have estimated the association between real-world natalizumab persistence behavior and relapse-related outcomes. OBJECTIVES:To (a) examine the impact of using nat...

journal_title：Journal of managed care & specialty pharmacy

authors： McQueen RB,Livingston T,Vollmer T,Corboy J,Buckley B,Allen RR,Nair K,Campbell JD

更新日期：2015-03-01 00:00:00

abstract：:DISCLOSURES: Funding for the study referred to in this letter was contributed by Bayer Healthcare. Xia and Williamson are employees of Bayer Healthcare. Roth, Carlson, and Sullivan are consultants to Bayer Healthcare. Carlson also reports fees from Adaptive Biotechnologies, unrelated to the study. Roth reports consult...

journal_title：Journal of managed care & specialty pharmacy

authors： Roth JA,Carlson JJ,Xia F,Williamson T,Sullivan SD

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Current evidence of the effects of pharmacy services on asthma outcomes are not conclusive, since most pharmacy services comprise a variety of interventions. OBJECTIVE:To assess the effect of a service containing self-management support delivered by community pharmacists to patients with asthma. METHODS:A ...

journal_title：Journal of managed care & specialty pharmacy

authors： Dokbua S,Dilokthornsakul P,Chaiyakunapruk N,Saini B,Krass I,Dhippayom T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Recent evidence has demonstrated that, over 12 months, pharmacy costs associated with switching nonadherent recently relapsed patients from oral atypical antipsychotics (OAAs) to once-monthly paliperidone palmitate (PP1M) were offset by reduced relapse rates and schizophrenia-related health care costs. In ad...

journal_title：Journal of managed care & specialty pharmacy

authors： El Khoury AC,Pilon D,Morrison L,Shak N,Llaneza A,Kim E,Lefebvre P

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Adherence to adjuvant endocrine therapy (AET) for estrogen receptor-positive breast cancer remains suboptimal, which suggests that women are not getting the full benefit of the treatment to reduce breast cancer recurrence and mortality. The majority of studies on adherence to AET focus on identifying factors...

journal_title：Journal of managed care & specialty pharmacy

authors： Farias AJ,Hansen RN,Zeliadt SB,Ornelas IJ,Li CI,Thompson B

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The management of sickle cell disease (SCD), an inherited, chronic, and multifaceted condition, is associated with considerable health care resource utilization (HRU) and costs, especially for Medicaid. Anemia affects most patients with SCD and correlates with end-organ damage (EOD), such as stroke, chronic ...

journal_title：Journal of managed care & specialty pharmacy

authors： Campbell A,Cong Z,Agodoa I,Song X,Martinez DJ,Black D,Lew CR,Varker H,Chan C,Lanzkron S

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Adjuvant trastuzumab treatment is administered to early stage breast cancer patients in physician office (POV) or hospital outpatient (HOP) settings. OBJECTIVE:To identify treatment patterns, utilization, and costs by site of care (POV vs. HOP) of patients with adjuvant treatment of breast cancer with trast...

journal_title：Journal of managed care & specialty pharmacy

authors： Parthan A,Santos E,Becker L,Small A,Lalla D,Brammer M,Teitelbaum A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Allergy immunotherapy (AIT) is the only available treatment that alters the natural course of allergies and has possible disease-modifying effects. AIT is administered primarily via subcutaneous injection delivered in a physician's office. Few studies have been conducted in the United States or Canada to eva...

journal_title：Journal of managed care & specialty pharmacy

authors： Blume SW,Yeomans K,Allen-Ramey F,Smith N,Kim H,Lockey RF,Nichol MB

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Encouraging generic drug use has reduced health care costs for payers and consumers, but the availability of therapeutically interchangeable medications or generic medications of choice is not equal across disease states. The extent to which systems of care are able to substitute with generics is not well un...

journal_title：Journal of managed care & specialty pharmacy

authors： Walton SM,Rash C,Lambert BL,Galanter WL

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Clinical trials impose exclusion criteria that may limit the generalizability of results. OBJECTIVES:To (a) determine the percentage of real-world patients who would qualify for psoriasis randomized controlled trials; (b) ascertain differences between moderate-to-severe psoriasis patients who would be eligi...

journal_title：Journal of managed care & specialty pharmacy

authors： Malatestinic W,Nordstrom B,Wu JJ,Goldblum O,Solotkin K,Lin CY,Kistler K,Fraeman K,Johnston J,Hawley LL,Sicignano N,Araujo A

更新日期：2017-03-01 00:00:00

abstract：:BACKGROUND: Basal insulin is often recommended as the initial therapy for patients with type 2 diabetes who require insulin treatment. Adequate adherence is critical to diabetes management, yet suboptimal insulin adherence has been reported. Second-generation long-acting (SGLA) insulin has higher dosing flexibility an...

journal_title：Journal of managed care & specialty pharmacy

authors： Zhang H,Barner JC,Moczygemba LR,Rascati KL

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Overuse and misuse of prescription opioids is associated with increased morbidity and mortality and places a significant cost burden on health systems. OBJECTIVE:To estimate annual statewide spending for prescription opioids in Rhode Island. METHODS:A cross-sectional study of opioids dispensed from retail ...

journal_title：Journal of managed care & specialty pharmacy

authors： Aroke H,Buchanan A,Wen X,Ragosta P,Koziol J,Kogut S

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Medication reconciliation is considered to be an important strategy for increasing the safety of medication use. However, few studies have been carried out showing the effect of a medication reconciliation program on the incidence of reconciliation errors (REs) in oncological patients treated in the outpatie...

journal_title：Journal of managed care & specialty pharmacy

authors： Vega TG,Sierra-Sánchez JF,Martínez-Bautista MJ,García-Martín F,Suárez-Carrascosa F,Baena-Cañada JM

更新日期：2016-06-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this article. The author has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Lever HM

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Lipid screening determines eligibility for statins and other cardiovascular risk reduction interventions. OBJECTIVE:To examine trends in lipid screening among adults aged ≥20 years in a large, multiethnic, integrated health care delivery system in southern California. METHODS:Temporal trends in lipid scree...

journal_title：Journal of managed care & specialty pharmacy

authors： Grant DSL,Scott RD,Harrison TN,Cheetham TC,Chang SC,Hsu JY,Wei R,Boklage SH,Romo-LeTourneau V,Reynolds K

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Cancer is a major cause of mortality and a major contributor to health care costs in the United States. An increasing number of cancer patients are treated with oral cancer therapy. Older patients are more likely to have cancer and to be at risk for adherence problems with oral cancer drugs. As a result of s...

journal_title：Journal of managed care & specialty pharmacy

authors： Kaisaeng N,Harpe SE,Carroll NV

更新日期：2014-07-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this commentary. Brummel has consulted, presented, or was engaged in an advisory board for UCB, Boerhinger Ingelheim, Pfizer, and Lilly. Sorenson has nothing to disclose. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Brummel AR,Sorensen TD

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic, hyper-proliferative dermatological condition associated with joint symptoms known as psoriatic arthritis (PsA). In a 2013 review, the total economic burden of PsA was estimated at $51.7-$63.2 billion. The economic burden of moderate to severe psoriasis patients has reduced significant...

journal_title：Journal of managed care & specialty pharmacy

authors： Lee S,Xie L,Wang Y,Vaidya N,Baser O

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Adherence to antiretrovirals (ARVs) is critical to achieving durable virologic suppression. OBJECTIVE:To investigate risk factors of poor adherence and the effect of suboptimal adherence on health care resource utilization (HCRU) and costs in Medicaid patients. METHODS:A retrospective longitudinal study wa...

journal_title：Journal of managed care & specialty pharmacy

authors： Dunn K,Lafeuille MH,Jiao X,Romdhani H,Emond B,Woodruff K,Pesa J,Tandon N,Lefebvre P

更新日期：2018-10-01 00:00:00

abstract：DISCLOSURES:No funding was involved in the writing of this letter. Outside of the submitted work, Hiligsmann has received research grants through institution from Amgen, Radius Health, UCB, and Teva/Theramex. Reginster has received research grants and/or consulting fees from Servier, Novartis, Negma, Lilly, Wyeth, Amge...

journal_title：Journal of managed care & specialty pharmacy

authors： Hiligsmann M,Reginster JY,Silverman S

更新日期：2020-03-01 00:00:00

abstract：DISCLOSURES:No funding supported the writing of this letter. Preblick, Ali, and DasMahapatra are employees and shareholders of Sanofi Genzyme. Gray is a postdoctoral fellow at Sanofi Genzyme and Rutgers University. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Preblick R,Gray C,Ali T,DasMahapatra P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Adherence to treatment is correlated with treatment success in chronic myeloid leukemia (CML). CVS Specialty explored novel methods to improve adherence in this population to ensure optimal adherence and lower the risk of unsuccessful treatment. One novel program explored involved an interactive 2-way clinic...

journal_title：Journal of managed care & specialty pharmacy

authors： Sawicki C,Friend KE,Patel R,Polinski JM,Singh S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:National guidelines and initiatives have promoted the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) for patients with diabetes. The University of Arizona Medication Management Center (UA-MMC) is contracted by Medicare health plans, pharmacy benefit managers ...

journal_title：Journal of managed care & specialty pharmacy

authors： Hurwitz JT,Grizzle AJ,Augustine J,Rehfeld R,Wild A,Abraham I

更新日期：2016-01-01 00:00:00