Specialty Drug Price Trends in the Federal 340B Drug Discount Program.

abstract：BACKGROUND:This study is an evaluation of a discharge intervention that occurred in multiple hospitals across Maryland. In this program, patients received medications at their bedside before discharge with the goal of reducing the risk of primary nonadherence to prescribed medications. OBJECTIVE:To test if the interve...

journal_title：Journal of managed care & specialty pharmacy

authors： Segal JB,Apfel A,Brotman DJ,Shermock KM,Clark JM

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Acromegaly is a chronic disorder characterized by excess growth hormone secretion and elevated insulin-like growth factor-1 levels most often caused by a pituitary adenoma. Clinical presentation of the disease includes coarsening of the facial features, soft-tissue swelling of the hands and feet, and overgro...

journal_title：Journal of managed care & specialty pharmacy

authors： Placzek H,Xu Y,Mu Y,Begelman SM,Fisher M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The approval of new oral disease-modifying drugs (DMDs), such as fingolimod, dimethyl fumarate (DMF), and teriflunamide, has considerably expanded treatment options for relapsing forms of multiple sclerosis (MS). However, data describing the use of these agents in routine clinical practice are limited. OBJE...

journal_title：Journal of managed care & specialty pharmacy

authors： Desai RJ,Mahesri M,Gagne JJ,Hurley E,Tong A,Chitnis T,Minden S,Spettell CM,Matlin OS,Shrank WH,Choudhry NK

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Adherence to antiretrovirals (ARVs) is critical to achieving durable virologic suppression. OBJECTIVE:To investigate risk factors of poor adherence and the effect of suboptimal adherence on health care resource utilization (HCRU) and costs in Medicaid patients. METHODS:A retrospective longitudinal study wa...

journal_title：Journal of managed care & specialty pharmacy

authors： Dunn K,Lafeuille MH,Jiao X,Romdhani H,Emond B,Woodruff K,Pesa J,Tandon N,Lefebvre P

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Previous research finds significant variation in spending and utilization across regions, with little evidence of differences in outcomes. While such findings have been interpreted as evidence that spending can be reduced without compromising patient outcomes, the link between spending variation and outcomes...

journal_title：Journal of managed care & specialty pharmacy

authors： Baumgardner J,Shahabi A,Linthicum M,Vine S,Zacker C,Lakdawalla D

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Individuals with Down syndrome (DS) experience various comorbidities in excess of the prevalence seen among the non-DS population. However, the extent of the excess burden of comorbidities specifically within commercially and publicly insured DS populations aged < 21 years is not currently known. OBJECTIVES...

journal_title：Journal of managed care & specialty pharmacy

authors： Kong AM,Hurley D,Evans KA,Brixner D,Csoboth C,Visootsak J

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Value-based insurance design (VBID) waives or reduces prescription copayments in order to decrease member cost barriers to refilling medications. Medication therapy management (MTM) is a member clinical intervention designed to reinforce members' knowledge of their medications, which addresses barriers to me...

journal_title：Journal of managed care & specialty pharmacy

authors： Peaslee A,Wickizer M,Olson J,Topp R

更新日期：2016-11-01 00:00:00

abstract：:Section 3002 of the 21st Century Cures Act, which was signed into law in December 2016, requires the FDA to develop one or more sets of new guidances regarding the collection of patient experience data. To explore how patient-reported outcomes (PROs) can support value-based care and discuss challenges to using PROs mo...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-03-21 00:00:00

abstract：:In a study published last year in the October 2014 issue of the Journal of Managed Care Specialty Pharmacy, Trivedi et al. compared treatment patterns of dasatinib and nilotinib as second-line tyrosine kinase inhibitors (TKI) therapy in chronic myeloid leukemia (CML) patients during the first year of treatment.1 Trive...

journal_title：Journal of managed care & specialty pharmacy

authors： Chen L,Wu EQ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Overuse and misuse of prescription opioids is associated with increased morbidity and mortality and places a significant cost burden on health systems. OBJECTIVE:To estimate annual statewide spending for prescription opioids in Rhode Island. METHODS:A cross-sectional study of opioids dispensed from retail ...

journal_title：Journal of managed care & specialty pharmacy

authors： Aroke H,Buchanan A,Wen X,Ragosta P,Koziol J,Kogut S

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Multiple sclerosis (MS) is a neurological degenerative chronic condition without cure. However, long-term disease-modifying therapies (DMTs) help reduce the severity of MS symptoms. Adherence to DMTs is key to their success. Several studies have analyzed what makes patients adherent to their DMTs. As new DMT...

journal_title：Journal of managed care & specialty pharmacy

authors： Higuera L,Carlin CS,Anderson S

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Formulary management within a limited budget is critical, especially for specialty drugs, which are used for serious medical conditions and are very expensive. Despite attempts to summarize the pertinent evidence, it is uncertain whether data needs of formulary decision makers for specialty drugs are satisfi...

journal_title：Journal of managed care & specialty pharmacy

authors： Choi Y,Navarro RP

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:All Department of Veterans Affairs Medical Centers (VAMCs) operate under a single national drug formulary, yet substantial variation in prescribing and spending exists across facilities. Local management of the national formulary may differ across VAMCs and may be one cause of this variation. OBJECTIVE:To c...

journal_title：Journal of managed care & specialty pharmacy

authors： Radomski TR,Good CB,Thorpe CT,Zhao X,Marcum ZA,Glassman PA,Lowe J,Mor MK,Fine MJ,Gellad WF

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Clinical trials have shown that direct oral anticoagulants (DOACs)-including dabigatran, rivaroxaban, apixaban, and edoxaban-are at least as effective and safe as warfarin for the risk of stroke/systemic embolism (SE) and major bleeding (MB) in patients with atrial fibrillation (AF). However, few studies hav...

journal_title：Journal of managed care & specialty pharmacy

authors： Amin A,Keshishian A,Trocio J,Dina O,Le H,Rosenblatt L,Liu X,Mardekian J,Zhang Q,Baser O,Nadkarni A,Vo L

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Adherence to biologic disease-modifying antirheumatic drugs (bDMARDs) among patients with rheumatoid arthritis (RA) is often suboptimal in routine clinical practice. Low or nonadherence can reduce the effectiveness of bDMARD therapies. OBJECTIVE:To evaluate filling of newly prescribed initial bDMARDs for th...

journal_title：Journal of managed care & specialty pharmacy

authors： Harnett J,Wiederkehr D,Gerber R,Gruben D,Bourret J,Koenig A

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Despite evidence showing the benefits of treatment intensification following an elevated hemoglobin A1c (A1c), clinical inertia, or failure to establish and/or escalate treatment to achieve treatment goals, is a concern among patients diagnosed with type 2 diabetes (T2DM). Clinical inertia may contribute to ...

journal_title：Journal of managed care & specialty pharmacy

authors： Ruiz-Negrón N,Wander C,McAdam-Marx C,Pesa J,Bailey RA,Bellows BK

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Clinical pharmacy services were initiated at 7 of 11 clinics within a primary care network (PCN), which was designated as a patient-centered medical home and was affiliated with a large academic medical center in October 2014. The goal of the service was to target patients with uncontrolled chronic condition...

journal_title：Journal of managed care & specialty pharmacy

authors： Prudencio J,Cutler T,Roberts S,Marin S,Wilson M

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Adherence to adjuvant endocrine therapy (AET) for estrogen receptor-positive breast cancer remains suboptimal, which suggests that women are not getting the full benefit of the treatment to reduce breast cancer recurrence and mortality. The majority of studies on adherence to AET focus on identifying factors...

journal_title：Journal of managed care & specialty pharmacy

authors： Farias AJ,Hansen RN,Zeliadt SB,Ornelas IJ,Li CI,Thompson B

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Costs associated with biologic switching and discontinuation can be high in chronic inflammatory diseases. Inappropriate use of medications may have cost implications for both payers and patients. Understanding of biologic utilization and switching rates is lacking among patients with ankylosing spondylitis ...

journal_title：Journal of managed care & specialty pharmacy

authors： Yi E,Dai D,Piao OW,Zheng JZ,Park Y

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Nearly half of statin users discontinue therapy within the first year of treatment. Nonadherence to statin therapy may lead to an increased risk of atherosclerotic cardiovascular disease and, thus, higher costs due to hospitalizations. Value-based care models, such as accountable care organizations (ACO), ar...

journal_title：Journal of managed care & specialty pharmacy

authors： Tamargo C,Sando K,Prados Y,Cowart K

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Since multiple myeloma (MM) incurs a substantial economic burden in care management, more and more discussion has been generated in recent years about the costs of novel antimyeloma drugs and their associated value. Because of these costs, economic assessment that quantifies value of care over the long-term ...

journal_title：Journal of managed care & specialty pharmacy

authors： Chen Y,Lairson DR,Chan W,Huo J,Du XL

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Medication reconciliation is considered to be an important strategy for increasing the safety of medication use. However, few studies have been carried out showing the effect of a medication reconciliation program on the incidence of reconciliation errors (REs) in oncological patients treated in the outpatie...

journal_title：Journal of managed care & specialty pharmacy

authors： Vega TG,Sierra-Sánchez JF,Martínez-Bautista MJ,García-Martín F,Suárez-Carrascosa F,Baena-Cañada JM

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The functional impairment associated with migraine can cause physical, emotional, and economic ramifications that can affect occupational, academic, social, and family life. Understanding the relationship between headache-free days (HFDs) and the disease burden of migraine may help with decisions regarding t...

journal_title：Journal of managed care & specialty pharmacy

authors： Lipton RB,Lee L,Saikali NP,Bell J,Cohen JM

更新日期：2020-10-01 00:00:00

abstract：DISCLOSURES:The author provides consulting services to the pharmaceutical industry, including manufacturers, health plans, employers, and specialty pharmacies, and is a member of the editorial advisory board of Specialty Pharmacy News. The author reports no financial or other conflicts of interest related to the subjec...

journal_title：Journal of managed care & specialty pharmacy

authors： Rubinstein E

更新日期：2016-08-01 00:00:00

abstract：DISCLOSURES:No outside funding supported the writing of this letter. Farley has received funding from the National Community Pharmacy Association for previous research. Schondelmeyer advises the University of Minnesota Health Benefit plan on its prescription drug coverage. Urick has received a grant from Cardinal Healt...

journal_title：Journal of managed care & specialty pharmacy

authors：

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The Biologics Price Competition and Innovation Act, introduced as part of the Affordable Care Act, directed the FDA to create an approval pathway for biologic products shown to be biosimilar or interchangeable with an FDA-approved innovator drug. These biosimilars will not be chemically identical to the refe...

journal_title：Journal of managed care & specialty pharmacy

authors： AMCP Task Force on Biosimilar Collective Intelligence Systems.,Baldziki M,Brown J,Chan H,Cheetham TC,Conn T,Daniel GW,Hendrickson M,Hilbrich L,Johnson A,Miller SB,Moore T,Motheral B,Priddy SA,Raebel MA,Randhawa G,Surratt

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:National guidelines and initiatives have promoted the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) for patients with diabetes. The University of Arizona Medication Management Center (UA-MMC) is contracted by Medicare health plans, pharmacy benefit managers ...

journal_title：Journal of managed care & specialty pharmacy

authors： Hurwitz JT,Grizzle AJ,Augustine J,Rehfeld R,Wild A,Abraham I

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Diabetes is a leading cause of morbidity, mortality, and medical resource utilization in the United States and worldwide. Treatment is aimed at keeping blood glucose levels close to normal and preventing or delaying medical complications. It has been estimated that only 50% of patients with diabetes in the U...

journal_title：Journal of managed care & specialty pharmacy

authors： Saundankar V,Peng X,Fu H,Ascher-Svanum H,Rodriguez A,Ali A,Slabaugh L,Young P,Louder A

更新日期：2016-05-01 00:00:00

abstract：:BACKGROUND: The economic burden of food allergy is large; however, costs specific to individuals with peanut allergy experiencing reactions to peanuts remain to be evaluated. As the prevalence of peanut allergy continues to increase in children, a better understanding of the cost of care is warranted. OBJECTIVE: To as...

journal_title：Journal of managed care & specialty pharmacy

authors： Blaiss MS,Meadows JA,Yu S,Robison DR,Hass SL,Norrett KE,Guerin A,Latremouille-Viau D,Tilles SA

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:The management of sickle cell disease (SCD), an inherited, chronic, and multifaceted condition, is associated with considerable health care resource utilization (HRU) and costs, especially for Medicaid. Anemia affects most patients with SCD and correlates with end-organ damage (EOD), such as stroke, chronic ...

journal_title：Journal of managed care & specialty pharmacy

authors： Campbell A,Cong Z,Agodoa I,Song X,Martinez DJ,Black D,Lew CR,Varker H,Chan C,Lanzkron S

更新日期：2020-09-01 00:00:00