Diagnostic and prognostic utility of WBC counts and cell population data in patients with COVID-19.

abstract：INTRODUCTION:Venous blood (VB) sampling for complete blood count (CBC) via venipuncture is the basic method for the daily evaluation of hematological patients. However, several issues during this process, such as venipuncture difficulty and repetitive attempts, may cause pain, phlebitis, hematomas, inadequate sampling,...

journal_title：International journal of laboratory hematology

authors： Oudatzis G,Tsagarakis NJ,Paterakis G,Vasileiou P,Xenou E,Maraki P,Pangrati T,Angelopoulou MK,Vassilakopoulos TP,Konstantopoulos K

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Presence of schistocytes in peripheral blood smear supporting haemolysis is important for diagnosis and decision-making in paediatric haemolytic uraemic syndrome (HUS). High observer dependency and requirement of expertise for peripheral smear evaluation propels us to think of other modalities to overcome ...

journal_title：International journal of laboratory hematology

authors： Govindarajan S,Bhatia P,Dawman L,Tiewsoh K

更新日期：2021-02-01 00:00:00

abstract：:The foundation of laboratory hematologic diagnosis is the complete blood count and review of the peripheral smear. In patients with anemia, the peripheral smear permits interpretation of diagnostically significant red blood cell (RBC) findings. These include assessment of RBC shape, size, color, inclusions, and arrang...

journal_title：International journal of laboratory hematology

authors： Ford J

更新日期：2013-06-01 00:00:00

abstract：INTRODUCTION:Thrombocytopenia-absent radius (TAR) syndrome is a rare autosomal recessive disease. Patients are compound heterozygotes for a loss-of-function allele, which in most cases is a large genomic deletion on chromosome 1q21.1 containing the RBM8A gene, and a noncoding variant located in the 5'UTR (rs139428292) ...

journal_title：International journal of laboratory hematology

authors： Nicchia E,Giordano P,Greco C,De Rocco D,Savoia A

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Capillary electrophoresis (CE) is a high-resolution method for detection of hemoglobin Constant Spring (Hb CS). METHODS:The levels of Hb CS quantified by CE were compared among three groups of samples including heterozygote and homozygote of Hb CS as well as Hb H-CS disease classified by DNA molecular dia...

journal_title：International journal of laboratory hematology

authors： Pornprasert S,Panyasai S,Waneesorn J,Kongthai K,Singboottra P

更新日期：2012-04-01 00:00:00

abstract：:Several intracytoplasmic morphological changes in the plasma cells of multiple myeloma have been described previously. However, Auer rod-like inclusions are rarely found in these types of cells. Here, we report a case of multiple myeloma with Auer rod-like, needle-shaped intracytoplasmic inclusions in plasma cells. A ...

journal_title：International journal of laboratory hematology

authors： Hütter G,Nowak D,Blau IW,Thiel E

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:The complete blood count (CBC) with differential leukocyte count (DIFF) is an important part of clinical laboratory analyses and provides crucial data for clinicians. Delivery time after blood collection and conditions of storage is known to affect the reliability of results of some hematologic parameters....

journal_title：International journal of laboratory hematology

authors： Cornet E,Behier C,Troussard X

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:To measure direct factor Xa inhibitor (apixaban, edoxaban, rivaroxaban) concentrations, dedicated chromogenic anti-Xa assays are recommended as suitable methods to provide rapid drug quantification. Moreover, the high-performance liquid chromatography with ultraviolet detection (HPLC-UV) is reported as a r...

journal_title：International journal of laboratory hematology

authors： Cini M,Legnani C,Padrini R,Cosmi B,Dellanoce C,De Rosa G,Marcucci R,Pengo V,Poli D,Testa S,Palareti G

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:In the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway, STAT3 is one of the most prominent prognosis factors for cancer and leukemia. STAT3 activation might promote cellular transformation and therefore have an important role in human tumors. This study aimed to i...

journal_title：International journal of laboratory hematology

authors： Zhong Y,Feng J,Chen B,Cheng L,Li Y,Qian J,Ding J,Gao F,Xia G

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:While hyperparasitemia is considered an important indicator for the development of severe malaria, there is currently no consensus on the quantitative definition of hyperparasitemia. This study was conducted to establish a cutoff point for peripheral parasitemia among patients with Plasmodium falciparum ma...

journal_title：International journal of laboratory hematology

authors： Tangpukdee N,Krudsood S,Kano S,Wilairatana P

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:Malaria is a life-threatening infectious disease, which has been for long confined to specific endemic areas. Nevertheless, the recent increase in immigration flows from endemic regions and imported cases has reemphasized many diagnostic challenges in Western countries, thus paving the way to introduce rap...

journal_title：International journal of laboratory hematology

authors： Buoro S,Manenti B,Seghezzi M,Moioli V,Bagorria M,Callegaro A,Ottomano C,Lippi G

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:With the progression of blood analysis technology, hematology analyzers become more complex and diverse. How to choose a superb instrument is a challenge for the laboratories. In the essay, we studied whether the newest BC-6000 hematology analyzer meets the needs of a clinical hematology laboratory. METHO...

journal_title：International journal of laboratory hematology

authors： Shen Y,Cao J,Zhou Z,Wang Y,Shen Y,He J

更新日期：2019-10-01 00:00:00

abstract：:Promoter hypermethylation plays an important role in the inactivation of cancer-related genes. This abnormality occurs early in leukemogenesis and seems to be associated with poor prognosis in myelodsplastic syndrome (MDS). The identification of more inactivated tumor suppressor genes contributing to the development o...

journal_title：International journal of laboratory hematology

authors： Qian J,Yao DM,Lin J,Wang YL,Han LX,Xu WR,Wu CY

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:Gene expression profiling (GEP) risk models in multiple myeloma are based on 3'-end microarrays. We hypothesized that GEP risk signatures could retain prognostic power despite being translated and applied to whole-transcript microarray data. METHODS:We studied CD138-positive bone marrow plasma cells in a ...

journal_title：International journal of laboratory hematology

authors： Hermansen NE,Borup R,Andersen MK,Vangsted AJ,Clausen NT,Kristensen DL,Nielsen FC,Gimsing P

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Immature platelet fraction (IPF) is a parameter for reticulated platelets. A high percentage IPF (%-IPF) is indicative of consumptive or recovering thrombocytopenic disorders in contrast to a low %-IPF seen in aplastic states. Absolute IPF (A-IPF) specifically reflects the number of immature platelets in c...

journal_title：International journal of laboratory hematology

authors： Ko YJ,Kim H,Hur M,Choi SG,Moon HW,Yun YM,Hong SN

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:Direct oral anticoagulants (DOAC) are commonly prescribed and measuring drug levels may be useful in a number of contexts. However, data on DOAC level measurement and their clinical utility in real-world studies are limited. METHODS:We carried out a 2-year retrospective cohort study of DOAC levels measure...

journal_title：International journal of laboratory hematology

authors： Denny NDR,Keighley L,Siganporia Z,Thachil J,Nash MJ

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Lnc-IRF2-3 and Lnc-ZNF667-AS1 were recently studied as a positive biomarker for many tumor cells. However, experimental studies found that they are associated with worse outcomes in B-CLL. METHODS:A prospective case study was conducted on 135 B-CLL patients that were compared to thirty healthy controls. The...

journal_title：International journal of laboratory hematology

authors： El-Khazragy N,Esmaiel MA,Mohamed MM,Hassan NS

更新日期：2020-06-01 00:00:00

abstract：:Modern photo-optical coagulometers collect optical data in the form of reaction curves and offer a possibility to determine clotting times at different points of clot formation by using different evaluation modes. The objectives of this study were to determine the possible impact of an evaluation mode on activated par...

journal_title：International journal of laboratory hematology

authors： Milos M,Herak DC,Zadro R

更新日期：2010-02-01 00:00:00

abstract：:Although most patients with peripheral T-cell lymphoma (PTCL) show clonal rearrangement of T-cell receptor genes, few PTCLs show recurrent chromosomal abnormalities. We describe here a rare chromosomal rearrangement, t(14;19)(q11.2;q13.3), in a Lennert's lymphoma, a variant of PTCL, not otherwise specified. Sequential...

journal_title：International journal of laboratory hematology

authors： Shin SY,Jang S,Park CJ,Chi HS,Lee KH,Huh J,Seo EJ

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:Peripheral blood smear (PBS) review is a routine laboratory test which requires pathologist's interpretation when abnormal indices, atypical cells, or critical findings are identified. Real-time remote digital microscopy (DM) can potentially facilitate rapid review when an on-site pathologist is not availa...

journal_title：International journal of laboratory hematology

authors： Haninger DM,Nassiri M,Settembre ED,Zhang S,Zhou J

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:Atypical chronic lymphocytic leukemia (aCLL) is a morphologic variant found in approximately 25% of patients with chronic lymphocytic leukemia (CLL). Although aCLL has a more aggressive course compared to typical CLL (tCLL), it is not usually reported. This retrospective study used digital microscopy to mo...

journal_title：International journal of laboratory hematology

authors： Marionneaux S,Maslak P,Keohane EM

更新日期：2014-08-01 00:00:00

abstract：:Bone marrow BCR-ABL transcript levels were monitored serially by real-time quantitative PCR in 46 imatinib-treated chronic myeloid leukemia patients after achieving complete cytogenetic response (CCyR) for a median of 42 months (range: 9-53). Of 41 patients in continuous CCyR, 32 and nine could achieve a >/=3-log (MMo...

journal_title：International journal of laboratory hematology

authors： Qin YZ,Liu YR,Zhu HH,Li JL,Ruan GR,Zhang Y,Jiang Q,Jiang H,Li LD,Chang Y,Huang XJ,Chen SS

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Hematological patients, receiving intensive chemotherapy (predominantly acute leukemia patients), have repeated postchemotherapy periods with severe bone marrow suppression. As a result, these patients require regular monitoring of the complete blood counts (CBC) for optimal patient care. To reduce the strai...

journal_title：International journal of laboratory hematology

authors： Kristian Kur D,Thøgersen D,Kjeldsen L,Friis-Hansen L

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:To observe changes in the complete blood count (CBC) venous blood parameters of healthy children and establish appropriate reference intervals (RIs). METHODS:Overall, 4066 healthy children were selected and divided into four groups: infants, toddlers, preschool-age children and school-age children. Venous b...

journal_title：International journal of laboratory hematology

authors： Li J,Zhang H,Huang X,Zhang J,Wu X

更新日期：2019-10-01 00:00:00

abstract：:Treatment of malignant blood disorders, such as leukemia, that can provide a better chance of long-term remission involves myeloablation followed by transplantation of matched donor hematopoietic stem cells (HSCs). For successful engraftment and re-establishment of hematopoiesis to occur in the recipient, the transpla...

journal_title：International journal of laboratory hematology

authors： Lam BS,Adams GB

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:The blood count provides qualitative and quantitative essential information on bloodlines. Reference hematologic parameters have been established in children and neonates, but few data are available regarding the premature population during the first month of life. The main objective of this study was to e...

journal_title：International journal of laboratory hematology

authors： Roudil P,Vasselon C,Trombert-Paviot B,Berger C,Patural H

更新日期：2017-06-01 00:00:00

abstract：INTRODUCTION:Aberrant activation of Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway leads to deregulated proliferation, differentiation, or apoptosis of normal cells. One of the members of this family, JAK2, plays a very important role in metabolizing carcinogens and medications. This...

journal_title：International journal of laboratory hematology

authors： Zhong Y,Wu J,Ma R,Cao H,Wang Z,Ding J,Cheng L,Feng J,Chen B

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:This study was aimed to compare the analytical performance of traditional and new parameters and morphological flags of CAL-8000 and XN-9000. The automated differential leukocyte count (DIFF profile) and morphological flags were compared with optical microscopy (OM). METHODS:A total of 1025 peripheral blo...

journal_title：International journal of laboratory hematology

authors： Buoro S,Mecca T,Seghezzi M,Manenti B,Azzarà G,Dominoni P,Crippa A,Ottomano C,Lippi G

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:Thrombotic complications are a main concern in patients with myeloproliferative neoplasms. Recently, a gain-of-function mutation of the gene encoding the JAK2 tyrosine kinase that results in a valine-to-phenylalanine substitution at position 617 (V617F) has been described. Since the description of the JAK2...

journal_title：International journal of laboratory hematology

authors： Xavier SG,Gadelha T,Rezende SM,Zalcberg IR,Spector N

更新日期：2011-04-01 00:00:00

abstract：:Complex chromosomal aberrations (CCA) can be detected in a substantial proportion of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), which are associated with very poor prognosis. Conventional cytogenetics (CC) cannot accurately define the specific alterations in CCA. Multiplex fluorescence in situ h...

journal_title：International journal of laboratory hematology

authors： Xu W,Li JY,Liu Q,Zhu Y,Pan JL,Qiu HR,Xue YQ

更新日期：2010-02-01 00:00:00