A rare case of Lennert's type peripheral T-cell lymphoma with t(14;19)(q11.2;q13.3).

abstract：INTRODUCTION:With the progression of blood analysis technology, hematology analyzers become more complex and diverse. How to choose a superb instrument is a challenge for the laboratories. In the essay, we studied whether the newest BC-6000 hematology analyzer meets the needs of a clinical hematology laboratory. METHO...

journal_title：International journal of laboratory hematology

authors： Shen Y,Cao J,Zhou Z,Wang Y,Shen Y,He J

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Clot waveform analysis (CWA), a new methodology to assess coagulation process, can be usefully applied in various clinical settings. However, its clinical use is limited mainly because of the absence of standardization. No consensus exists regarding the wavelengths at which CWA has to be performed what is ...

journal_title：International journal of laboratory hematology

authors： Evrard J,Siriez R,Morimont L,Thémans P,Laloy J,Bouvy C,Gheldof D,Mullier F,Dogné JM,Douxfils J

更新日期：2019-06-01 00:00:00

abstract：:The paucity of clinical reports in the world literature suggests that, as a disease entity, haemoglobin SE compound heterozygosity is of negligible importance. In view of the significant community prevalence of this haemoglobinopathy in the Sultanate of Oman where it is the second most prevalent sickling disorder, a h...

journal_title：International journal of laboratory hematology

authors： Knox-Macaulay HH,Ahmed MM,Gravell D,Al-Kindi S,Ganesh A

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:To observe changes in the complete blood count (CBC) venous blood parameters of healthy children and establish appropriate reference intervals (RIs). METHODS:Overall, 4066 healthy children were selected and divided into four groups: infants, toddlers, preschool-age children and school-age children. Venous b...

journal_title：International journal of laboratory hematology

authors： Li J,Zhang H,Huang X,Zhang J,Wu X

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Point-of-care (POC) international normalized ratio (INR) values above an institutional cutoff are confirmed in the laboratory using a gold standard venous specimen. This can be problematic in a pediatric setting. METHOD:In this study, 449 consecutive POC INR results were compared to an INR performed in th...

journal_title：International journal of laboratory hematology

authors： Williams VK

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening thrombotic microangiopathy (TMA) characterized by the severe deficiency of ADAMTS13 activity (<10%). Rapid ADAMTS13 testing is crucial for early diagnosis and optimal management of TTP patients and other TMAs. The objective of this study ...

journal_title：International journal of laboratory hematology

authors： Pascual C,Nieto JM,Fidalgo T,Seguí IG,Díaz-Ricart M,Docampo MF,Del Rio J,Salinas R

更新日期：2020-12-02 00:00:00

abstract：INTRODUCTION:Variability in FVIII measurement is a recognized problem. There are limited data for samples containing recombinant Factor VIII Fc fusion protein (rFVIIIFc). Many studies use samples for which factor concentrate has been spiked into FVIII deficient plasma in vitro. This approach requires validation. AIM/M...

journal_title：International journal of laboratory hematology

authors： Kitchen S,Jennings I,Makris M,Kitchen DP,Woods TAL,Walker ID

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Several factors influence the severity of Plasmodium falciparum; here, we investigate the impact of alpha+-thalassaemia genotype on P. falciparum parasitemia and prevalence of severe anaemia amongst microcytic children from Kumasi, Ghana. METHODS:Seven hundred and thirty-two children (≤10 years) with P. f...

journal_title：International journal of laboratory hematology

authors： Opoku-Okrah C,Gordge M,Kweku Nakua E,Abgenyega T,Parry M,Robertson C,Smith CL

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Gene expression profiling (GEP) risk models in multiple myeloma are based on 3'-end microarrays. We hypothesized that GEP risk signatures could retain prognostic power despite being translated and applied to whole-transcript microarray data. METHODS:We studied CD138-positive bone marrow plasma cells in a ...

journal_title：International journal of laboratory hematology

authors： Hermansen NE,Borup R,Andersen MK,Vangsted AJ,Clausen NT,Kristensen DL,Nielsen FC,Gimsing P

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:In order to correctly manage the paediatric patients affected with haemostatic disorders, age-appropriate reference intervals should be used. The purpose of this study was to establish age-specific reference intervals for prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (aPT...

journal_title：International journal of laboratory hematology

authors： Liu J,Dai Y,Yuan E,Li Y,Wang Q,Wang L,Su Y

更新日期：2019-10-01 00:00:00

abstract：:Eosinophilia is typically secondary, that is, reactive, in nature and is associated with a wide variety of neoplastic and non-neoplastic disorders. Clonal eosinophilia is also seen in a wide variety of hematopoietic neoplasms, and sub-classification can be diagnostically challenging. A proper evaluation of persistent ...

journal_title：International journal of laboratory hematology

authors： Larsen RL,Savage NM

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Autoimmune haemolytic anaemia (AIHA) is defined as the increased destruction of red blood cells (RBCs) in the presence of anti-RBC autoantibodies and/or complement. Its pathogenesis is multifactorial and includes changes in mechanisms of cytokine production and functionality. A number of recent studies hav...

journal_title：International journal of laboratory hematology

authors： D'Abronzo LS,Barros MM,Bordin JO,Figueiredo MS

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:To retrospectively analyze epidemiological, clinical and hematological characteristics of COVID-19 patients. METHODS:The demographic, symptoms, and physiological parameters of 88 patients were collected and analyzed. The performance of complete blood count (CBC) indexes for monitoring and predicting the s...

journal_title：International journal of laboratory hematology

authors： Zhang H,Cao X,Kong M,Mao X,Huang L,He P,Pan S,Li J,Lu Z

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Deficiencies of protein C, protein S, and antithrombin are the main inherited risk factors in Thai patients with venous thromboembolism, although the prevalence is not high. METHODS:To evaluate the appropriate use of the testing for these proteins, the test orders of 503 patients were retrospectively revi...

journal_title：International journal of laboratory hematology

authors： Tientadakul P,Chinthammitr Y,Sanpakit K,Wongwanit C,Nilanont Y

更新日期：2011-12-01 00:00:00

abstract：:The value of nontransferrin-bound iron (NTBI) as an index of iron overload in patients with thalassemia has been evaluated; however, data in patients with sickle cell disease (SCD) is limited. NTBI levels were evaluated in a cross-sectional study of 43 transfused patients with SCD. Patient charts were reviewed for dem...

journal_title：International journal of laboratory hematology

authors： Inati A,Musallam KM,Cappellini MD,Duca L,Taher AT

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:Frequent PT (INR) testing may represent a problem for patients on warfarin treatment, and capillary or small-volume tubes may be more appropriate for such patients. A demand for small-volume tubes also comes from pediatric wards. Yet, while various small-volume tubes are available, they have not been prope...

journal_title：International journal of laboratory hematology

authors： Onelöv L,Basmaji R,Svensson A,Nilsson M,Antovic JP

更新日期：2015-10-01 00:00:00

abstract：INTRODUCTION:Monocytosis is a frequent trigger for blood smear review in a routine hematology laboratory whereas chronic myelomonocytic leukemia (CMML) is infrequent and arises mostly in elderly patients. In order to define the best workflow for monocytosis, we studied three diagnostic approaches: the classical morphol...

journal_title：International journal of laboratory hematology

authors： Zhu J,Sourdeau E,Aubert H,Clauser S,Maillon A,Capron C,Jondeau K,Ronez E,Schillinger F,Garnache-Ottou F,Cornet E,Bardet V

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:These recommendations are intended to develop a consensus in the previously published papers as to which parameters and what values should be considered critical. A practical guide on the standardization of critical results management in haematology laboratories would be beneficial as part of good laborato...

journal_title：International journal of laboratory hematology

authors： Keng TB,De La Salle B,Bourner G,Merino A,Han JY,Kawai Y,Peng MT,McCafferty R,International Council for Standardization in Haematology (ICSH).

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Atypical chronic lymphocytic leukemia (aCLL) is a morphologic variant found in approximately 25% of patients with chronic lymphocytic leukemia (CLL). Although aCLL has a more aggressive course compared to typical CLL (tCLL), it is not usually reported. This retrospective study used digital microscopy to mo...

journal_title：International journal of laboratory hematology

authors： Marionneaux S,Maslak P,Keohane EM

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Immediate reporting of critical values or test results significantly outside the normal range has a growing role in the management of patients, especially in life-threatening conditions. Due to the lack of international consensus, diverse approaches are used for determination of thresholds, reporting, docume...

journal_title：International journal of laboratory hematology

authors： Dorgalaleh A,Shiravand Y,Dabbagh A,Tabibian S,Hosseini MS,Mansouri Tourghabeh H,Rashidpanah J,Narouei F,Shams M,Gholami MS,Saneei Moghaddam E,Shahreki H

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:To measure direct factor Xa inhibitor (apixaban, edoxaban, rivaroxaban) concentrations, dedicated chromogenic anti-Xa assays are recommended as suitable methods to provide rapid drug quantification. Moreover, the high-performance liquid chromatography with ultraviolet detection (HPLC-UV) is reported as a r...

journal_title：International journal of laboratory hematology

authors： Cini M,Legnani C,Padrini R,Cosmi B,Dellanoce C,De Rosa G,Marcucci R,Pengo V,Poli D,Testa S,Palareti G

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Thrombotic complications are a main concern in patients with myeloproliferative neoplasms. Recently, a gain-of-function mutation of the gene encoding the JAK2 tyrosine kinase that results in a valine-to-phenylalanine substitution at position 617 (V617F) has been described. Since the description of the JAK2...

journal_title：International journal of laboratory hematology

authors： Xavier SG,Gadelha T,Rezende SM,Zalcberg IR,Spector N

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:Physiological changes during pregnancy affect routine tests for iron deficiency. The reticulocyte haemoglobin equivalent (RET-He) and serum-soluble transferrin receptor (sTfR) assay are newer diagnostic parameters for the detection of iron deficiency, combined in the Thomas diagnostic plot. We used this pl...

journal_title：International journal of laboratory hematology

authors： Weyers R,Coetzee MJ,Nel M

更新日期：2016-04-01 00:00:00

abstract：:The PENTRA 60C(+) hematology analyzer provides a complete blood cell (CBC) count, including a five-part differential (5-DIFF) count and two leukocyte subpopulations, i.e. large immature cells (LIC's) and atypical lymphocytes (ALY's). We evaluated its analytical performance and assessed agreement with the ADVIA 2120, i...

journal_title：International journal of laboratory hematology

authors： Guerti K,Vertessen F,Daniëls L,Van Der Planken M

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:The STA R Max® 2 is a new coagulation analyser developed by Diagnostica Stago, able to perform clotting, chromogenic and immuno-turbidimetric tests. A pre-analytical module build into the cap-piercing needle performs the sample integrity verification (sample tube filling and measurement of haemolysis, icte...

journal_title：International journal of laboratory hematology

authors： Cupaiolo R,Govaerts D,Blauwaert M,Cauchie P

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:The IgV(H) mutational status of B-cell chronic lymphocytic leukemia (B-CLL) is of prognostic value. Expression of ZAP-70 in B-CLL is a surrogate marker for IgV(H) unmutated (UM). As determination of IgV(H) mutational status involves a methodology currently unavailable for most clinical laboratories, it is ...

journal_title：International journal of laboratory hematology

authors： Marquez ME,Deglesne PA,Suarez G,Romano E

更新日期：2011-04-01 00:00:00

abstract：:The diagnosis of iron deficiency in hospital patients can be difficult in the presence of inflammation. A raised serum transferrin receptor (sTfR) level is useful as a marker of iron deficiency as it is unaffected by inflammation. However, diseases that cause an increase in erythropoietic activity can also result in a...

journal_title：International journal of laboratory hematology

authors： Ong KH,Tan HL,Tam LP,Hawkins RC,Kuperan P

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Thrombocytopenia-absent radius (TAR) syndrome is a rare autosomal recessive disease. Patients are compound heterozygotes for a loss-of-function allele, which in most cases is a large genomic deletion on chromosome 1q21.1 containing the RBM8A gene, and a noncoding variant located in the 5'UTR (rs139428292) ...

journal_title：International journal of laboratory hematology

authors： Nicchia E,Giordano P,Greco C,De Rocco D,Savoia A

更新日期：2016-08-01 00:00:00

abstract：:The progressive shortening of telomeres and the activation of telomerase are considered to be one of the important mechanisms in cellular immortalization and disease progression. Bone marrow samples were collected from 148 patients with acute leukemia (AL). Based on the stage of the disease, patients were divided into...

journal_title：International journal of laboratory hematology

authors： Wang Y,Fang M,Sun X,Sun J

更新日期：2010-04-01 00:00:00

abstract：:Bone marrow BCR-ABL transcript levels were monitored serially by real-time quantitative PCR in 46 imatinib-treated chronic myeloid leukemia patients after achieving complete cytogenetic response (CCyR) for a median of 42 months (range: 9-53). Of 41 patients in continuous CCyR, 32 and nine could achieve a >/=3-log (MMo...

journal_title：International journal of laboratory hematology

authors： Qin YZ,Liu YR,Zhu HH,Li JL,Ruan GR,Zhang Y,Jiang Q,Jiang H,Li LD,Chang Y,Huang XJ,Chen SS

更新日期：2008-08-01 00:00:00