Red blood cell morphology.

abstract：INTRODUCTION:The investigation of platelet function by aggregometry requires specialist equipment and is labour intensive. We have developed an automated platelet aggregation method on a routine coagulation analyser. METHODS:We used a CS-2000i (Sysmex) with prototype software to perform aggregation in platelet-rich pl...

journal_title：International journal of laboratory hematology

authors： Lawrie AS,Kobayashi K,Lane PJ,Mackie IJ,Machin SJ

更新日期：2014-08-01 00:00:00

abstract：INTRODUCTION:Clot waveform analysis (CWA), a new methodology to assess coagulation process, can be usefully applied in various clinical settings. However, its clinical use is limited mainly because of the absence of standardization. No consensus exists regarding the wavelengths at which CWA has to be performed what is ...

journal_title：International journal of laboratory hematology

authors： Evrard J,Siriez R,Morimont L,Thémans P,Laloy J,Bouvy C,Gheldof D,Mullier F,Dogné JM,Douxfils J

更新日期：2019-06-01 00:00:00

abstract：INTRODUCTION:The collection of diagnostic blood specimens for routine haematological testing (RHT) is traditionally performed with tourniquet. However, the transillumination devices based on cold near-infrared LEDs have been formerly proposed as a valuable tool for identifying reliable venous accesses, especially in pa...

journal_title：International journal of laboratory hematology

authors： Lima-Oliveira G,Lippi G,Salvagno GL,Montagnana M,Scartezini M,Guidi GC,Picheth G

更新日期：2011-10-01 00:00:00

abstract：:Measurement of the Haemoglobin F in red cell haemolysates is important in the diagnosis of δβ thalassaemia, hereditary persistence of fetal haemoglobin (HPFH) and in the diagnosis and management of sickle cell disease. The distribution of Hb F in red cells is useful in the diagnosis of HPFH and in the assessment of fe...

journal_title：International journal of laboratory hematology

authors： Stephens AD,Angastiniotis M,Baysal E,Chan V,Davis B,Fucharoen S,Giordano PC,Hoyer JD,Mosca A,Wild B,International Council for The Standardisation of Haematology (ICSH).

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Hematological patients, receiving intensive chemotherapy (predominantly acute leukemia patients), have repeated postchemotherapy periods with severe bone marrow suppression. As a result, these patients require regular monitoring of the complete blood counts (CBC) for optimal patient care. To reduce the strai...

journal_title：International journal of laboratory hematology

authors： Kristian Kur D,Thøgersen D,Kjeldsen L,Friis-Hansen L

更新日期：2021-02-01 00:00:00

abstract：:The ongoing COVID-19 pandemic has had a profound worldwide impact on the laboratory hematology community. Nevertheless, the pace of COVID-19 hematology-related research has continued to accelerate and has established the role of laboratory hematology data for many purposes including disease prognosis and outcome. The ...

journal_title：International journal of laboratory hematology

authors： Bell R,Zini G,d'Onofrio G,Rogers HJ,Lee YS,Frater JL

更新日期：2020-11-12 00:00:00

abstract：INTRODUCTION:With the progression of blood analysis technology, hematology analyzers become more complex and diverse. How to choose a superb instrument is a challenge for the laboratories. In the essay, we studied whether the newest BC-6000 hematology analyzer meets the needs of a clinical hematology laboratory. METHO...

journal_title：International journal of laboratory hematology

authors： Shen Y,Cao J,Zhou Z,Wang Y,Shen Y,He J

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:The STA R Max® 2 is a new coagulation analyser developed by Diagnostica Stago, able to perform clotting, chromogenic and immuno-turbidimetric tests. A pre-analytical module build into the cap-piercing needle performs the sample integrity verification (sample tube filling and measurement of haemolysis, icte...

journal_title：International journal of laboratory hematology

authors： Cupaiolo R,Govaerts D,Blauwaert M,Cauchie P

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:Monocytosis is a frequent trigger for blood smear review in a routine hematology laboratory whereas chronic myelomonocytic leukemia (CMML) is infrequent and arises mostly in elderly patients. In order to define the best workflow for monocytosis, we studied three diagnostic approaches: the classical morphol...

journal_title：International journal of laboratory hematology

authors： Zhu J,Sourdeau E,Aubert H,Clauser S,Maillon A,Capron C,Jondeau K,Ronez E,Schillinger F,Garnache-Ottou F,Cornet E,Bardet V

更新日期：2019-12-01 00:00:00

abstract：:Platelets play a central role in physiological hemostasis and also in pathological thrombosis. It is well established that congenital or acquired abnormalities of platelet function are associated with a heightened risk of bleeding of variable severity and excessive hemorrhage after surgery or trauma. Several kinds of ...

journal_title：International journal of laboratory hematology

authors： Podda G,Femia EA,Cattaneo M

更新日期：2016-05-01 00:00:00

abstract：:The paucity of clinical reports in the world literature suggests that, as a disease entity, haemoglobin SE compound heterozygosity is of negligible importance. In view of the significant community prevalence of this haemoglobinopathy in the Sultanate of Oman where it is the second most prevalent sickling disorder, a h...

journal_title：International journal of laboratory hematology

authors： Knox-Macaulay HH,Ahmed MM,Gravell D,Al-Kindi S,Ganesh A

更新日期：2007-08-01 00:00:00

abstract：INTRODUCTION:Iron-deficient erythropoiesis attributable to nutritional deficiency is the most common cause of anemia in early childhood. Beckman Coulter has proposed new parameters: red blood cell size factor (RSf) and low hemoglobin density (LHD%). [Formula: see text] The aims of the present communication were to esta...

journal_title：International journal of laboratory hematology

authors： Osta V,Caldirola MS,Fernandez M,Marcone MI,Tissera G,Pennesi S,Ayuso C

更新日期：2013-08-01 00:00:00

abstract：:Myelodysplastic syndrome (MDS) with hypocellular bone marrow (BM) is often difficult to distinguish from aplastic anemia (AA). Furthermore, the diagnosis of MDS with low blast counts and normal karyotype may be problematic. These issues highlight the need for a reliable marker for the diagnosis of MDS. This study was ...

journal_title：International journal of laboratory hematology

authors： Huh HJ,Chae SL,Lee M,Hong KS,Mun YC,Seong CM,Chung WS,Huh JW

更新日期：2009-06-01 00:00:00

abstract：:Successful adoptive immunotherapy for leukemia depends on the generation of T cells that can specifically react with malignant cells. Dendritic cells (DCs) are important antigen-presenting cells in the development of antileukemia T-cell responses. Mononuclear cells (MNC) were isolated from peripheral blood or bone mar...

journal_title：International journal of laboratory hematology

authors： Tong XM,Yao HP,Qian WB,Zhu LF,Fu ZH,Huang ZL,Jin J

更新日期：2008-10-01 00:00:00

abstract：:Although most patients with peripheral T-cell lymphoma (PTCL) show clonal rearrangement of T-cell receptor genes, few PTCLs show recurrent chromosomal abnormalities. We describe here a rare chromosomal rearrangement, t(14;19)(q11.2;q13.3), in a Lennert's lymphoma, a variant of PTCL, not otherwise specified. Sequential...

journal_title：International journal of laboratory hematology

authors： Shin SY,Jang S,Park CJ,Chi HS,Lee KH,Huh J,Seo EJ

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:The Sysmex XN-series is a new automated hematology analyzer designed to improve the accuracy of cell counts and the specificity of the flagging events. METHODS:The basic characteristics and the performance of new measurement channels of the XN were evaluated and compared with the Sysmex XE-2100 and the ma...

journal_title：International journal of laboratory hematology

authors： Seo JY,Lee ST,Kim SH

更新日期：2015-04-01 00:00:00

abstract：INTRODUCTION:The complete blood count (CBC) with differential leukocyte count (DIFF) is an important part of clinical laboratory analyses and provides crucial data for clinicians. Delivery time after blood collection and conditions of storage is known to affect the reliability of results of some hematologic parameters....

journal_title：International journal of laboratory hematology

authors： Cornet E,Behier C,Troussard X

更新日期：2012-12-01 00:00:00

abstract：:Bone marrow aspiration and biopsy can be a painful procedure. Sedation techniques may make this investigation more acceptable to patients, but have the potential to cause life-threatening complications, as well as requiring additional staff and equipment for safe administration. We assessed the use of Entonox, a 50 : ...

journal_title：International journal of laboratory hematology

authors： Gudgin EJ,Besser MW,Craig JI

更新日期：2008-02-01 00:00:00

abstract：:Promoter hypermethylation plays an important role in the inactivation of cancer-related genes. This abnormality occurs early in leukemogenesis and seems to be associated with poor prognosis in myelodsplastic syndrome (MDS). The identification of more inactivated tumor suppressor genes contributing to the development o...

journal_title：International journal of laboratory hematology

authors： Qian J,Yao DM,Lin J,Wang YL,Han LX,Xu WR,Wu CY

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:New methods for coagulation tests require careful assessment before routine use. We evaluated the analytical performance of five new coagulation assays for measuring prothrombin time (PT) and activated partial thromboplastin time (aPTT). METHODS:PT Rec, PT Owren, aPTT, aPTT Lupus and aPTT Screen assays (R...

journal_title：International journal of laboratory hematology

authors： Kitchen S,Geisen U,Kappelmayer J,Quehenberger P,Drieß J,Lowe A,Jones R,Boehm JG,Miles G,Rozsnyai G

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:It is widely recognized that plasma cells (PCs) are under-represented in flow cytometry (FC) studies, but the causes of this phenomenon are poorly understood. We sought to study potential variables that affect PC recovery by flow cytometry (FC) in the analysis of plasma cell myeloma (PCM). METHODS:We retr...

journal_title：International journal of laboratory hematology

authors： Cogbill CH,Spears MD,Vantuinen P,Harrington AM,Olteanu H,Kroft SH

更新日期：2015-12-01 00:00:00

abstract：:The pathogenesis of acute myeloid leukaemias (AML) frequently requires at least 3 mutations in different cellular pathways. In many cases, mutations in proliferation/survival mechanisms and differentiation pathways are involved. Genetic aberrations explain the pathogenesis of AML, provide prognostic criteria and guide...

journal_title：International journal of laboratory hematology

authors： Merino A,Boldú L,Ermens A

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Women are at higher risk of venous thromboembolism (VTE) during pregnancy and the puerperium. Global coagulation assays (GCAs), including thromboelastography (TEG), thrombin generation using the calibrated automated thrombogram (CAT) and fibrin generation using the overall haemostatic potential assay (OHP)...

journal_title：International journal of laboratory hematology

authors： O'Keefe D,Lim HY,Tham J,Ho P,Hui L

更新日期：2020-11-10 00:00:00

abstract：:Prediction of the timing of platelet recovery after chemotherapy and hematopoietic stem cell transplantation (HSCT) allows for optimal platelet transfusion. We assessed the clinical utility of the percentage value of the immature platelet fraction (IPF%) monitored using an XE-2100 automated hematology analyzer to pred...

journal_title：International journal of laboratory hematology

authors： Yamaoka G,Kubota Y,Nomura T,Inage T,Arai T,Kitanaka A,Saigo K,Iseki K,Baba N,Taminato T

更新日期：2010-12-01 00:00:00

abstract：:Advances in lab-on-a-chip technologies enabled programmable, reconfigurable, and scalable manipulation of a variety of laboratory procedures. Samples, reagents, and fluids can be precisely controlled; buffer temperature, pH, and concentration control systems as well as a variety of detection systems can be integrated ...

journal_title：International journal of laboratory hematology

authors： Park S,Moon HS,Lee DS,Kim HC,Chun H

更新日期：2013-10-01 00:00:00

abstract：:Though not very common, solid tumor involvement of the bone marrow (BM) may have serious consequences. Recent studies have shown that mean platelet volume (MPV) is a good indicator for BM disease in the differential diagnosis of thrombocytopenia. We investigated the significance of MPV in the diagnosis of BM metastasi...

journal_title：International journal of laboratory hematology

authors： Aksoy S,Kilickap S,Hayran M,Harputluoglu H,Koca E,Dede DS,Erman M,Turker A

更新日期：2008-06-01 00:00:00

abstract：:Chronic active Epstein-Barr virus infection of T- and NK-cell type, systemic form, is a rare entity within the spectrum of EBV-driven T- and NK-cell lymphoproliferative disorders. Established diagnostic criteria and a characteristic clinical course help to differentiate it from other closely related EBV-positive neopl...

journal_title：International journal of laboratory hematology

authors： Ondrejka SL,Hsi ED

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:The workflow in clinical flow cytometry laboratories must constantly be reviewed to develop technical procedures that improve quality and productivity and reduce costs. Using the Beckman Coulter dry coating technology, we customized a ten-color tube with dried antibody reagents, designated the Duraclone sc...

journal_title：International journal of laboratory hematology

authors： Correia RP,Rajab A,Bento LC,Alexandre AM,Vaz AC,Schimidell D,Pedro EC,Perin FS,Nozawa ST,Barroso RS,Bacal NS

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Direct oral anticoagulants (DOAC) are commonly prescribed and measuring drug levels may be useful in a number of contexts. However, data on DOAC level measurement and their clinical utility in real-world studies are limited. METHODS:We carried out a 2-year retrospective cohort study of DOAC levels measure...

journal_title：International journal of laboratory hematology

authors： Denny NDR,Keighley L,Siganporia Z,Thachil J,Nash MJ

更新日期：2019-04-01 00:00:00

abstract：:The progressive shortening of telomeres and the activation of telomerase are considered to be one of the important mechanisms in cellular immortalization and disease progression. Bone marrow samples were collected from 148 patients with acute leukemia (AL). Based on the stage of the disease, patients were divided into...

journal_title：International journal of laboratory hematology

authors： Wang Y,Fang M,Sun X,Sun J

更新日期：2010-04-01 00:00:00