Assessing maternal clotting function with novel global coagulation assays: A prospective pilot study.

abstract：:The diagnosis of iron deficiency in hospital patients can be difficult in the presence of inflammation. A raised serum transferrin receptor (sTfR) level is useful as a marker of iron deficiency as it is unaffected by inflammation. However, diseases that cause an increase in erythropoietic activity can also result in a...

journal_title：International journal of laboratory hematology

authors： Ong KH,Tan HL,Tam LP,Hawkins RC,Kuperan P

更新日期：2008-12-01 00:00:00

abstract：:Bone marrow aspiration and biopsy can be a painful procedure. Sedation techniques may make this investigation more acceptable to patients, but have the potential to cause life-threatening complications, as well as requiring additional staff and equipment for safe administration. We assessed the use of Entonox, a 50 : ...

journal_title：International journal of laboratory hematology

authors： Gudgin EJ,Besser MW,Craig JI

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:The Sysmex XN-series is a new automated hematology analyzer designed to improve the accuracy of cell counts and the specificity of the flagging events. METHODS:The basic characteristics and the performance of new measurement channels of the XN were evaluated and compared with the Sysmex XE-2100 and the ma...

journal_title：International journal of laboratory hematology

authors： Seo JY,Lee ST,Kim SH

更新日期：2015-04-01 00:00:00

abstract：:Several intracytoplasmic morphological changes in the plasma cells of multiple myeloma have been described previously. However, Auer rod-like inclusions are rarely found in these types of cells. Here, we report a case of multiple myeloma with Auer rod-like, needle-shaped intracytoplasmic inclusions in plasma cells. A ...

journal_title：International journal of laboratory hematology

authors： Hütter G,Nowak D,Blau IW,Thiel E

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:To study the effect of bortezomib alone or in combination with daunorubicin (DNR) on an mdr1 single-factor drug-resistant leukemia cell line K562/MDR1, a multifactor-resistant cell line K562/A02, a drug-sensitive cell line K562, and primary cells from acute myeloid leukemia patients. METHODS:The cell line...

journal_title：International journal of laboratory hematology

authors： Zheng B,Zhou R,Gong Y,Yang X,Shan Q

更新日期：2012-06-01 00:00:00

abstract：:The DM is an automated microscope, which performs WBC differential counts and monitors red cell morphology. The user either validates the cell recognition if the DM has correctly identified the WBCs or reclassifies the WBCs in the good category in case of a DM mis-assignment. Morphological anomalies of leukocytes, red...

journal_title：International journal of laboratory hematology

authors： Billard M,Lainey E,Armoogum P,Alberti C,Fenneteau O,Da Costa L

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Dehydration, fluid shifts or changes in coagulation occurring during air travel can trigger distinct reactions in the haematological system. Athletes are concerned that these effects might impair sporting performance, increase the risk of thrombosis or cause abnormalities in blood values that might be mist...

journal_title：International journal of laboratory hematology

authors： Schumacher YO,Klodt F,Nonis D,Pottgiesser T,Alsayrafi M,Bourdon PC,Voss SC

更新日期：2012-12-01 00:00:00

abstract：:Advances in lab-on-a-chip technologies enabled programmable, reconfigurable, and scalable manipulation of a variety of laboratory procedures. Samples, reagents, and fluids can be precisely controlled; buffer temperature, pH, and concentration control systems as well as a variety of detection systems can be integrated ...

journal_title：International journal of laboratory hematology

authors： Park S,Moon HS,Lee DS,Kim HC,Chun H

更新日期：2013-10-01 00:00:00

abstract：:The performance of factor VII (FVII) assays currently used by clinical laboratories was examined in North American Specialized Coagulation Laboratory Association (NASCOLA) proficiency tests. Data from 12 surveys conducted between 2008 and 2010, involving 20 unique specimens plus four repeat-tested specimens, were anal...

journal_title：International journal of laboratory hematology

authors： Zantek ND,Hsu P,Refaai MA,Ledford-Kraemer M,Meijer P,Van Cott EM

更新日期：2013-06-01 00:00:00

abstract：:The value of nontransferrin-bound iron (NTBI) as an index of iron overload in patients with thalassemia has been evaluated; however, data in patients with sickle cell disease (SCD) is limited. NTBI levels were evaluated in a cross-sectional study of 43 transfused patients with SCD. Patient charts were reviewed for dem...

journal_title：International journal of laboratory hematology

authors： Inati A,Musallam KM,Cappellini MD,Duca L,Taher AT

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:New methods for coagulation tests require careful assessment before routine use. We evaluated the analytical performance of five new coagulation assays for measuring prothrombin time (PT) and activated partial thromboplastin time (aPTT). METHODS:PT Rec, PT Owren, aPTT, aPTT Lupus and aPTT Screen assays (R...

journal_title：International journal of laboratory hematology

authors： Kitchen S,Geisen U,Kappelmayer J,Quehenberger P,Drieß J,Lowe A,Jones R,Boehm JG,Miles G,Rozsnyai G

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:It has been recently suggested that microparticles (MP) play a role in the pathogenesis of thrombotic complications. This study aimed to assess the contribution of procoagulant activity expressed by circulating MP in thrombotic events in MPN patients. METHODS:Seventy-four MPN patients were enrolled in a t...

journal_title：International journal of laboratory hematology

authors： Baccouche H,Ben Jemaa M,Chakroun A,Chadi S,Mahjoub S,Sfar I,Gorgi Y,Ben Romdhane N

更新日期：2017-10-01 00:00:00

abstract：:Successful adoptive immunotherapy for leukemia depends on the generation of T cells that can specifically react with malignant cells. Dendritic cells (DCs) are important antigen-presenting cells in the development of antileukemia T-cell responses. Mononuclear cells (MNC) were isolated from peripheral blood or bone mar...

journal_title：International journal of laboratory hematology

authors： Tong XM,Yao HP,Qian WB,Zhu LF,Fu ZH,Huang ZL,Jin J

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:The complete blood count (CBC) with differential leukocyte count (DIFF) is an important part of clinical laboratory analyses and provides crucial data for clinicians. Delivery time after blood collection and conditions of storage is known to affect the reliability of results of some hematologic parameters....

journal_title：International journal of laboratory hematology

authors： Cornet E,Behier C,Troussard X

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Point-of-care (POC) international normalized ratio (INR) values above an institutional cutoff are confirmed in the laboratory using a gold standard venous specimen. This can be problematic in a pediatric setting. METHOD:In this study, 449 consecutive POC INR results were compared to an INR performed in th...

journal_title：International journal of laboratory hematology

authors： Williams VK

更新日期：2019-02-01 00:00:00

abstract：:In the 8 years since the publication of the 4th edition of the WHO Classification of Hematopoietic and Lymphoid Tumours in 2008, there has been rapid accumulation of knowledge in the molecular genetics, biology, clinical behavior of many hematologic malignancies. Concepts and models have advanced to the point at which...

journal_title：International journal of laboratory hematology

authors： Hsi ED

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:Iron-deficient erythropoiesis attributable to nutritional deficiency is the most common cause of anemia in early childhood. Beckman Coulter has proposed new parameters: red blood cell size factor (RSf) and low hemoglobin density (LHD%). [Formula: see text] The aims of the present communication were to esta...

journal_title：International journal of laboratory hematology

authors： Osta V,Caldirola MS,Fernandez M,Marcone MI,Tissera G,Pennesi S,Ayuso C

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Physiological changes during pregnancy affect routine tests for iron deficiency. The reticulocyte haemoglobin equivalent (RET-He) and serum-soluble transferrin receptor (sTfR) assay are newer diagnostic parameters for the detection of iron deficiency, combined in the Thomas diagnostic plot. We used this pl...

journal_title：International journal of laboratory hematology

authors： Weyers R,Coetzee MJ,Nel M

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:Peripheral blood smear (PBS) review is a routine laboratory test which requires pathologist's interpretation when abnormal indices, atypical cells, or critical findings are identified. Real-time remote digital microscopy (DM) can potentially facilitate rapid review when an on-site pathologist is not availa...

journal_title：International journal of laboratory hematology

authors： Haninger DM,Nassiri M,Settembre ED,Zhang S,Zhou J

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:Beta globin deletion/duplication analysis may serve as a useful adjunct to sequence analysis. Our purpose was to develop a robust assay for beta globin deletion/duplication analysis and determine its role in evaluating patients with beta thalassemia. METHODS:A single tube semi-quantitative fluorescent PCR...

journal_title：International journal of laboratory hematology

authors： Mikula M,Buller-Burckle A,Gallivan M,Sun W,Franklin CR,Strom CM

更新日期：2011-06-01 00:00:00

abstract：INTRODUCTION:Monocytosis is a frequent trigger for blood smear review in a routine hematology laboratory whereas chronic myelomonocytic leukemia (CMML) is infrequent and arises mostly in elderly patients. In order to define the best workflow for monocytosis, we studied three diagnostic approaches: the classical morphol...

journal_title：International journal of laboratory hematology

authors： Zhu J,Sourdeau E,Aubert H,Clauser S,Maillon A,Capron C,Jondeau K,Ronez E,Schillinger F,Garnache-Ottou F,Cornet E,Bardet V

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:These recommendations are intended to develop a consensus in the previously published papers as to which parameters and what values should be considered critical. A practical guide on the standardization of critical results management in haematology laboratories would be beneficial as part of good laborato...

journal_title：International journal of laboratory hematology

authors： Keng TB,De La Salle B,Bourner G,Merino A,Han JY,Kawai Y,Peng MT,McCafferty R,International Council for Standardization in Haematology (ICSH).

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Deficiencies of protein C, protein S, and antithrombin are the main inherited risk factors in Thai patients with venous thromboembolism, although the prevalence is not high. METHODS:To evaluate the appropriate use of the testing for these proteins, the test orders of 503 patients were retrospectively revi...

journal_title：International journal of laboratory hematology

authors： Tientadakul P,Chinthammitr Y,Sanpakit K,Wongwanit C,Nilanont Y

更新日期：2011-12-01 00:00:00

abstract：INTRODUCTION:The direct thrombin inhibitor dabigatran interferes with thrombophilia screening and with the diagnosis of hemostasis disorders that develop during treatment with the anticoagulant. In vitro addition of idarucizumab, a humanized antibody fragment that binds dabigatran, to plasma samples containing dabigatr...

journal_title：International journal of laboratory hematology

authors： Jacquemin M,Toelen J,Feyen L,Schoeters J,Van Horenbeeck I,Vanlinthout I,Debasse M,Vanassche T,Peerlinck K,Verhamme P

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The MRD status detected using multiparameter flow cytometry (MFC) before allogeneic hematopoietic stem cell transplantation (allo-HSCT) has crucial prognostic value for patients with acute myeloid leukemia (AML) in morphologic complete remission (CR). We designed a novel panel of antibodies to identify aberr...

journal_title：International journal of laboratory hematology

authors： Wang Z,Guo M,Zhang Y,Xu S,Cheng H,Wu J,Zhang W,Hu X,Yang J,Wang J,Tang G

更新日期：2019-10-01 00:00:00

abstract：:The progressive shortening of telomeres and the activation of telomerase are considered to be one of the important mechanisms in cellular immortalization and disease progression. Bone marrow samples were collected from 148 patients with acute leukemia (AL). Based on the stage of the disease, patients were divided into...

journal_title：International journal of laboratory hematology

authors： Wang Y,Fang M,Sun X,Sun J

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:While hyperparasitemia is considered an important indicator for the development of severe malaria, there is currently no consensus on the quantitative definition of hyperparasitemia. This study was conducted to establish a cutoff point for peripheral parasitemia among patients with Plasmodium falciparum ma...

journal_title：International journal of laboratory hematology

authors： Tangpukdee N,Krudsood S,Kano S,Wilairatana P

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:Mean platelet volume (MPV) and platelet (PLT) count are the two major parameters that reflect the functions and activities of PLTs. The associations of MPV and PLT count with the occurrence and prognosis of stroke have not been fully clarified. This study aimed to investigate the association of MPV and PLT...

journal_title：International journal of laboratory hematology

authors： Du J,Wang Q,He B,Liu P,Chen JY,Quan H,Ma X

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Multiple types of mutations in the BCR-ABL1 kinase domain have been reported. We previously reported a common alternatively spliced BCR-ABL mRNA with a 35-nucleotide insertion (35INS). We report three novel alternative splicing mutants expressed as the dominant transcripts in patient with chronic myelogeno...

journal_title：International journal of laboratory hematology

authors： Ma W,Giles F,Zhang X,Wang X,Zhang Z,Lee TS,Yeh CH,Albitar M

更新日期：2011-06-01 00:00:00

abstract：INTRODUCTION:Autoimmune haemolytic anaemia (AIHA) is defined as the increased destruction of red blood cells (RBCs) in the presence of anti-RBC autoantibodies and/or complement. Its pathogenesis is multifactorial and includes changes in mechanisms of cytokine production and functionality. A number of recent studies hav...

journal_title：International journal of laboratory hematology

authors： D'Abronzo LS,Barros MM,Bordin JO,Figueiredo MS

更新日期：2012-08-01 00:00:00