2016 WHO Classification update-What's new in lymphoid neoplasms.

abstract：INTRODUCTION:These recommendations are intended to develop a consensus in the previously published papers as to which parameters and what values should be considered critical. A practical guide on the standardization of critical results management in haematology laboratories would be beneficial as part of good laborato...

journal_title：International journal of laboratory hematology

authors： Keng TB,De La Salle B,Bourner G,Merino A,Han JY,Kawai Y,Peng MT,McCafferty R,International Council for Standardization in Haematology (ICSH).

更新日期：2016-10-01 00:00:00

abstract：:Molecular monitoring of the BCR-ABL1 transcript in chronic myelogenous leukemia (CML) using quantitative real-time PCR (RQ-PCR) can be performed using either bone marrow (BM) or peripheral blood (PB). However, a recent report by Stock et al. [International Journal of Oncology 28 (2006) 1099] questioned the reliability...

journal_title：International journal of laboratory hematology

authors： Ballestrero A,Cirmena G,Dominietto A,Garuti A,Rocco I,Cea M,Moran E,Nencioni A,Miglino M,Raiola AM,Bacigalupo A,Patrone F

更新日期：2010-08-01 00:00:00

abstract：INTRODUCTION:Pathogen Inactivation allows to overcome microbial contamination and growth related to storage of platelets concentrates (PC) at room temperature. The aim of our study was to evaluate the platelet storage lesion extending the storage period of pathogen inactivated platelet concentrates over 7 days using an...

journal_title：International journal of laboratory hematology

authors： Diquattro M,De Francisci G,Bonaccorso R,Tagliavia AM,Marcatti M,Palma B,Agliastro R

更新日期：2013-12-01 00:00:00

abstract：:Myelodysplastic syndrome (MDS) with hypocellular bone marrow (BM) is often difficult to distinguish from aplastic anemia (AA). Furthermore, the diagnosis of MDS with low blast counts and normal karyotype may be problematic. These issues highlight the need for a reliable marker for the diagnosis of MDS. This study was ...

journal_title：International journal of laboratory hematology

authors： Huh HJ,Chae SL,Lee M,Hong KS,Mun YC,Seong CM,Chung WS,Huh JW

更新日期：2009-06-01 00:00:00

abstract：:The progressive shortening of telomeres and the activation of telomerase are considered to be one of the important mechanisms in cellular immortalization and disease progression. Bone marrow samples were collected from 148 patients with acute leukemia (AL). Based on the stage of the disease, patients were divided into...

journal_title：International journal of laboratory hematology

authors： Wang Y,Fang M,Sun X,Sun J

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:Immature platelet fraction (IPF) is a parameter for reticulated platelets. A high percentage IPF (%-IPF) is indicative of consumptive or recovering thrombocytopenic disorders in contrast to a low %-IPF seen in aplastic states. Absolute IPF (A-IPF) specifically reflects the number of immature platelets in c...

journal_title：International journal of laboratory hematology

authors： Ko YJ,Kim H,Hur M,Choi SG,Moon HW,Yun YM,Hong SN

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:TET2, a member of the Ten-Eleven translocation gene family, catalyzes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine in DNA. Low expression of TET2 has been reported as a prognostic factor for several types of malignancies in adult patients. However, there have been few data on the effect of...

journal_title：International journal of laboratory hematology

authors： Zhang P,Weng WW,Chen P,Zhang Y,Ruan JF,Ba DD,Xu WQ,Tang YM

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:New methods for coagulation tests require careful assessment before routine use. We evaluated the analytical performance of five new coagulation assays for measuring prothrombin time (PT) and activated partial thromboplastin time (aPTT). METHODS:PT Rec, PT Owren, aPTT, aPTT Lupus and aPTT Screen assays (R...

journal_title：International journal of laboratory hematology

authors： Kitchen S,Geisen U,Kappelmayer J,Quehenberger P,Drieß J,Lowe A,Jones R,Boehm JG,Miles G,Rozsnyai G

更新日期：2018-12-01 00:00:00

abstract：:Multiple myeloma (MM) is a malignant plasma cell disorder that involves multiple genetic abnormalities. Chimeric transcription factors, created by gene fusion as a result of chromosomal translocations, have been implicated in the pathogenesis of the disease. Here, we report the conventional cytogenetic analysis of a M...

journal_title：International journal of laboratory hematology

authors： Akalin I,Kutlay NY,Ilhan O,Tukun A

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:The investigation of platelet function by aggregometry requires specialist equipment and is labour intensive. We have developed an automated platelet aggregation method on a routine coagulation analyser. METHODS:We used a CS-2000i (Sysmex) with prototype software to perform aggregation in platelet-rich pl...

journal_title：International journal of laboratory hematology

authors： Lawrie AS,Kobayashi K,Lane PJ,Mackie IJ,Machin SJ

更新日期：2014-08-01 00:00:00

abstract：INTRODUCTION:Autoimmune haemolytic anaemia (AIHA) is defined as the increased destruction of red blood cells (RBCs) in the presence of anti-RBC autoantibodies and/or complement. Its pathogenesis is multifactorial and includes changes in mechanisms of cytokine production and functionality. A number of recent studies hav...

journal_title：International journal of laboratory hematology

authors： D'Abronzo LS,Barros MM,Bordin JO,Figueiredo MS

更新日期：2012-08-01 00:00:00

abstract：:The consistent multi-ethnic migrations of the last decades have considerably changed the epidemiology of the hemoglobinopathies. Healthy carriers of these conditions are present today in many nonendemic parts of the world, and severely affected children are now born where these diseases were previously rare or unknown...

journal_title：International journal of laboratory hematology

authors： Giordano PC

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Lnc-IRF2-3 and Lnc-ZNF667-AS1 were recently studied as a positive biomarker for many tumor cells. However, experimental studies found that they are associated with worse outcomes in B-CLL. METHODS:A prospective case study was conducted on 135 B-CLL patients that were compared to thirty healthy controls. The...

journal_title：International journal of laboratory hematology

authors： El-Khazragy N,Esmaiel MA,Mohamed MM,Hassan NS

更新日期：2020-06-01 00:00:00

abstract：:Significant advances have been made in our understanding of the structural basis for altered cell function in various inherited red cell membrane disorders with reduced red cell survival and resulting hemolytic anemia. The current review summarizes these advances as they relate to defining the molecular and structural...

journal_title：International journal of laboratory hematology

authors： Narla J,Mohandas N

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:Severe COVID-19 is often compounded by a prothrombotic state that is associated with poor outcomes. In this investigation, we aimed to evaluate ADAMTS13 activity, von Willebrand factor level (VWF:Ag), and the corresponding ADAMTS13 activity/VWF:Ag ratio, in patients with COVID-19 and for associations with ...

journal_title：International journal of laboratory hematology

authors： Henry BM,Benoit SW,de Oliveira MHS,Lippi G,Favaloro EJ,Benoit JL

更新日期：2020-12-03 00:00:00

abstract：INTRODUCTION:New generation osmotic gradient ektacytometry has become a powerful procedure for measuring red blood cell deformability and therefore for the diagnosis of red blood cell membrane disorders. In this study, we aim to provide further support to the usefulness of osmotic gradient ektacytometry for the differe...

journal_title：International journal of laboratory hematology

authors： Llaudet-Planas E,Vives-Corrons JL,Rizzuto V,Gómez-Ramírez P,Sevilla Navarro J,Coll Sibina MT,García-Bernal M,Ruiz Llobet A,Badell I,Velasco-Puyó P,Dapena JL,Mañú-Pereira MM

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Variability in FVIII measurement is a recognized problem. There are limited data for samples containing recombinant Factor VIII Fc fusion protein (rFVIIIFc). Many studies use samples for which factor concentrate has been spiked into FVIII deficient plasma in vitro. This approach requires validation. AIM/M...

journal_title：International journal of laboratory hematology

authors： Kitchen S,Jennings I,Makris M,Kitchen DP,Woods TAL,Walker ID

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Iron-deficient erythropoiesis attributable to nutritional deficiency is the most common cause of anemia in early childhood. Beckman Coulter has proposed new parameters: red blood cell size factor (RSf) and low hemoglobin density (LHD%). [Formula: see text] The aims of the present communication were to esta...

journal_title：International journal of laboratory hematology

authors： Osta V,Caldirola MS,Fernandez M,Marcone MI,Tissera G,Pennesi S,Ayuso C

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Several factors influence the severity of Plasmodium falciparum; here, we investigate the impact of alpha+-thalassaemia genotype on P. falciparum parasitemia and prevalence of severe anaemia amongst microcytic children from Kumasi, Ghana. METHODS:Seven hundred and thirty-two children (≤10 years) with P. f...

journal_title：International journal of laboratory hematology

authors： Opoku-Okrah C,Gordge M,Kweku Nakua E,Abgenyega T,Parry M,Robertson C,Smith CL

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:The study aims to evaluate the diagnostic utility of thyrogastric immune features in the identification of intrinsic factor antibody negative (IFA -ve) pernicious anaemia (PA) patients. METHODS:Clinico-pathological features of 'intrinsic factor antibody positive (IFA +ve) PA' and 'IFA -ve presumed PA' Chi...

journal_title：International journal of laboratory hematology

authors： Chan J,Chan HY

更新日期：2011-08-01 00:00:00

abstract：INTRODUCTION:Malaria is a life-threatening infectious disease, which has been for long confined to specific endemic areas. Nevertheless, the recent increase in immigration flows from endemic regions and imported cases has reemphasized many diagnostic challenges in Western countries, thus paving the way to introduce rap...

journal_title：International journal of laboratory hematology

authors： Buoro S,Manenti B,Seghezzi M,Moioli V,Bagorria M,Callegaro A,Ottomano C,Lippi G

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:With the progression of blood analysis technology, hematology analyzers become more complex and diverse. How to choose a superb instrument is a challenge for the laboratories. In the essay, we studied whether the newest BC-6000 hematology analyzer meets the needs of a clinical hematology laboratory. METHO...

journal_title：International journal of laboratory hematology

authors： Shen Y,Cao J,Zhou Z,Wang Y,Shen Y,He J

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:The Hematoflow (Beckman Coulter, USA) is a new automated hematology analyzer, which provides a 16-part white blood cell count (WBC) differential. METHODS:We evaluated the differential WBC count performance of the Hematoflow. 101 blood samples from patients were selected for comparison analysis. RESULTS:T...

journal_title：International journal of laboratory hematology

authors： Kim JE,Kim BR,Woo KS,Han JY

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:To observe changes in the complete blood count (CBC) venous blood parameters of healthy children and establish appropriate reference intervals (RIs). METHODS:Overall, 4066 healthy children were selected and divided into four groups: infants, toddlers, preschool-age children and school-age children. Venous b...

journal_title：International journal of laboratory hematology

authors： Li J,Zhang H,Huang X,Zhang J,Wu X

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Women are at higher risk of venous thromboembolism (VTE) during pregnancy and the puerperium. Global coagulation assays (GCAs), including thromboelastography (TEG), thrombin generation using the calibrated automated thrombogram (CAT) and fibrin generation using the overall haemostatic potential assay (OHP)...

journal_title：International journal of laboratory hematology

authors： O'Keefe D,Lim HY,Tham J,Ho P,Hui L

更新日期：2020-11-10 00:00:00

abstract：:Blood coagulation factor XIII (FXIII) plays a key role in the protection of fibrin clot against fibrinolysis, in the cross-linking of fibrin and its mechanical strength. The role of the FXIII-A subunit Val34Leu polymorphism with fatal primary intracerebral hemorrhages (PICH) has not been studied. We evaluated retrospe...

journal_title：International journal of laboratory hematology

authors： Antalfi B,Pongrácz E,Csiki Z,Mezei ZA,Shemirani AH

更新日期：2013-02-01 00:00:00

abstract：:The ongoing COVID-19 pandemic has had a profound worldwide impact on the laboratory hematology community. Nevertheless, the pace of COVID-19 hematology-related research has continued to accelerate and has established the role of laboratory hematology data for many purposes including disease prognosis and outcome. The ...

journal_title：International journal of laboratory hematology

authors： Bell R,Zini G,d'Onofrio G,Rogers HJ,Lee YS,Frater JL

更新日期：2020-11-12 00:00:00

abstract：INTRODUCTION:D-dimer (DD) assays are effective for the exclusion of deep-vein thrombosis (DVT), but point-of-care (POC) DD assays have not been fully evaluated. METHODS:We have compared five POC DD assays (Pathfast, Cardiac, Vidas, Stratus and NycoCard) with our routine DD method (Tinaquant), testing 60 samples from p...

journal_title：International journal of laboratory hematology

authors： Antovic JP,Höög Hammarström K,Forslund G,Eintrei J,Sten-Linder M

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:In acute myeloid leukemia (AML), it has been shown that AML-derived cells often remain sensitive to autophagy-inducing stimuli, leading to the idea that harnessing the autophagy can be pertinent to AML cytotoxic therapy. Despite this promising notion, to date, there is no comprehensive study addressing aut...

journal_title：International journal of laboratory hematology

authors： Zare-Abdollahi D,Safari S,Movafagh A,Ghadiani M,Tabarraee M,Riazi-Isfahani S,Gorji S,Keyvan L,Gachkar L

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening thrombotic microangiopathy (TMA) characterized by the severe deficiency of ADAMTS13 activity (<10%). Rapid ADAMTS13 testing is crucial for early diagnosis and optimal management of TTP patients and other TMAs. The objective of this study ...

journal_title：International journal of laboratory hematology

authors： Pascual C,Nieto JM,Fidalgo T,Seguí IG,Díaz-Ricart M,Docampo MF,Del Rio J,Salinas R

更新日期：2020-12-02 00:00:00