Associations between sleep disturbances and diabetes mellitus among blacks with metabolic syndrome: Results from the Metabolic Syndrome Outcome Study (MetSO).

abstract：:The term fibromyalgia describes a complex syndrome characterized by pain amplification, musculoskeletal discomfort, and systemic symptoms. Although its existence has been controversial, nearly all rheumatologists now accept fibromyalgia as a distinct diagnostic entity. In fact, in the United States it is the third or ...

journal_title：Annals of medicine

authors： Wallace DJ

更新日期：1997-02-01 00:00:00

abstract：:The pathophysiology of psychotic and other symptoms in schizophrenia remains a mystery despite decades of research. Even though it has been suspected for many years that autoimmune mechanisms may play a role in the pathophysiology of schizophrenia, firm evidence for this hypothesis has been lacking. Our studies, over ...

journal_title：Annals of medicine

authors： Ganguli R,Brar JS,Chengappa KN,Yang ZW,Nimgaonkar VL,Rabin BS

更新日期：1993-10-01 00:00:00

abstract：:The processes of glycation and oxidation play a significant role in the acceleration of atherosclerosis in diabetes mellitus. Glycation is thought not only to increase the susceptibility of low-density lipoprotein (LDL) to oxidation but also to enhance the propensity of vessel wall structural proteins to bind extravas...

journal_title：Annals of medicine

authors： Lopes-Virella MF,Virella G

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:H+/K+-ATPase is the target autoantigen in autoimmune gastritis (AIG), an organ-specific autoimmune disease with a strong hereditary component. AIM:To detect possible polymorphisms in H+/K+-ATPase alpha- and beta-subunits in AIG patients. METHODS:Blood samples from 12 Finnish AIG patients were sequenced for...

journal_title：Annals of medicine

authors： Oksanen AM,Lemmelä SM,Järvelä IE,Rautelin HI

更新日期：2006-01-01 00:00:00

abstract：:Apolipoprotein (apo) A-IV is involved in the metabolism of triglyceride-rich lipoproteins and high-density lipoproteins and may thus play an important role in lipid metabolism, although the precise physiological function of apo A-IV is unknown. Structural and functional alterations of apolipoproteins, caused by a vari...

journal_title：Annals of medicine

authors： Tenkanen H,Ehnholm C

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Several clinical studies have suggested possible increase in cardiovascular risk during and in the first weeks after an acute inflammatory disease. Using influenza vaccine as inflammatory stimulus, we investigated whether arterial endothelial dysfunction could persist beyond the inflammatory state, and wheth...

journal_title：Annals of medicine

authors： Liuba P,Aburawi EH,Pesonen E,Andersson S,Truedsson L,Ylä-Herttuala S,Holmberg L

更新日期：2007-01-01 00:00:00

abstract：:Diabetes in childhood and adolescence is a difficult, lifelong, evolving disorder. Insulin treatment is essential for the establishment and maintenance of optimal metabolic control but it is only part of a comprehensive child-focused management strategy which must be initiated at the time of diagnosis. Attention must ...

journal_title：Annals of medicine

authors： Swift PG

更新日期：1997-10-01 00:00:00

abstract：:This study examined the predictive validity of preadolescent Type A determinants for Type A dimensions in young adulthood (n = 375). Predictive variables, i.e. hyperactivity, aggression, social maladjustment and self-esteem were measured when the subjects were aged 12. Type A dimensions, i.e. hard-driving, competitive...

journal_title：Annals of medicine

authors： Keltikangas-Järvinen L,Räikkönen K,Keskivaara P,Pietikäinen M,Viikari J,Kaprio EA,Akerblom HK

更新日期：1991-02-01 00:00:00

abstract：:Aim: We investigated the outcomes of transcatheter (TAVR) and surgical aortic valve replacement (SAVR) in Finland during the last decade. Methods: The nationwide FinnValve registry included data from 6463 patients who underwent TAVR or SAVR with a bioprosthesis for aortic stenosis from 2008 to 2017. Results: The annua...

journal_title：Annals of medicine

authors： Mäkikallio T,Jalava MP,Husso A,Virtanen M,Laakso T,Ahvenvaara T,Tauriainen T,Maaranen P,Kinnunen EM,Dahlbacka S,Jaakkola J,Airaksinen J,Anttila V,Savontaus M,Laine M,Juvonen T,Valtola A,Raivio P,Eskola M,Niemelä M,

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Mortality from coronary heart disease (CHD) has been constantly higher in eastern late settlement regions compared to western early settlements in Finland, unrelated to classical risk factors. In line with this, eastern birthplace was an age-dependent predictor of severe coronary atherosclerosis and pre-hosp...

journal_title：Annals of medicine

authors： Tyynelä P,Goebeler S,Ilveskoski E,Mikkelsson J,Perola M,Lehtimäki T,Karhunen PJ

更新日期：2013-05-01 00:00:00

abstract：:Mixed connective tissue disease (MCTD) and systemic lupus erythematosus (SLE) are autoimmune diseases with a genetic background, and it is reasonable to suggest that aberrations in T cell receptor (TCR) genes could contribute to these diseases, as they play an important role in immune regulation. We studied TCR beta-c...

journal_title：Annals of medicine

authors： Ikäheimo IL,Tiilikainen AS,Hämeenkorpi R,Silvennoinen-Kassinen SH

更新日期：1994-04-01 00:00:00

abstract：:In the last three decades the incidence of metabolic syndrome (MetS) has been growing worldwide along with an increase of obesity, type 2 diabetes mellitus, and non-alcoholic fatty liver disease (NAFLD). In children and adolescents such epidemics are particularly worrisome, since the metabolic consequences in adulthoo...

journal_title：Annals of medicine

authors： Alisi A,Cianfarani S,Manco M,Agostoni C,Nobili V

更新日期：2012-02-01 00:00:00

abstract：:Introduction: The use of dipeptidyl peptidase-4 inhibitors in hospitalized patients is an area of active research. We aimed to compare the efficacy and the safety of the basal-bolus insulin regimen versus linagliptin-basal insulin in non-critically ill non-cardiac surgery patients in a real-world setting. Methods: We ...

journal_title：Annals of medicine

authors： Pérez-Belmonte LM,Osuna-Sánchez J,Millán-Gómez M,López-Carmona MD,Gómez-Doblas JJ,Cobos-Palacios L,Sanz-Cánovas J,Barbancho MA,Lara JP,Jiménez-Navarro M,Bernal-López MR,Gómez-Huelgas R

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Abnormal indices of angiogenesis have been reported in chronic heart failure (CHF). We tested the hypothesis that circulating angiogenin (a potent inducer of neovascularization in vivo) is higher in CHF patients compared with controls and associated with indices of CHF severity: brain natriuretic peptide (BN...

journal_title：Annals of medicine

authors： Patel JV,Sosin M,Gunarathne A,Hussain I,Davis RC,Hughes EA,Lip GY

更新日期：2008-01-01 00:00:00

abstract：:Recent results from controlled trials of adjuvant tamoxifen and oophorectomy in early breast cancer are reviewed. The results of the statistical overview performed by the Early Breast Cancer Trialists Collaborative Group are summarised, and some important questions left open by this overview are discussed. These inclu...

journal_title：Annals of medicine

authors： Blomqvist CP,Elomaa I,Rissanen P

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Teriparatide is a potent anabolic agent for severe osteoporosis. OBJECTIVES:A primary objective of this retrospective study was to define the efficacy of teriparatide in terms of bone mineral density (BMD) changes and relief of back pain in clinical practice. METHODS:The patient population comprises 119 os...

journal_title：Annals of medicine

authors： Koski AM,Löyttyniemi E,Väänänen H,Laine H,Niskanen L,Nevalainen PI,Korpi-Hyövälti E,Välimäki MJ

更新日期：2013-05-01 00:00:00

abstract：:INTRODUCTION. Premature ovarian failure (POF) can occur naturally at an early age or be due to iatrogenic agents. Indeed, ovaries are very sensitive to cytotoxic treatment, especially to radiation and alkylating agents. METHODS. Several options are currently available to preserve fertility in cancer patients and allow...

journal_title：Annals of medicine

authors： Donnez J,Silber S,Andersen CY,Demeestere I,Piver P,Meirow D,Pellicer A,Dolmans MM

更新日期：2011-01-01 00:00:00

abstract：:Hemostasis is traditionally defined as a physiological response to blood vessel injury and bleeding, which entails a co-ordinated process involving the blood vessel, platelets, and blood clotting proteins (i.e. coagulation factors). Hemostasis can be divided into primary and secondary components. The former rapidly in...

journal_title：Annals of medicine

authors： Lippi G,Franchini M,Montagnana M,Favaloro EJ

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:The objective of the present study was to examine the association between low-grade albuminuria and hearing impairment in the non-diabetic population. MATERIALS AND METHODS:Data from the Korean National Health and Nutrition Examination Survey 2011-2013 were used in the analyses. Participants were excluded...

journal_title：Annals of medicine

authors： Kang SH,Jung DJ,Choi EW,Park JW,Cho KH,Yoon KW,Do JY

更新日期：2015-01-01 00:00:00

abstract：:Cells with stem cell-like attributes, such as self-renewal and pluripotency, have been isolated from hematological malignancies and from several solid tumor types. Tumor-initiating cells, also referred to as cancer stem cells, are thought to be responsible for the initiation and growth of tumors. Like their normal cou...

journal_title：Annals of medicine

authors： Ribacka C,Pesonen S,Hemminki A

更新日期：2008-01-01 00:00:00

abstract：:Twenty-three randomly selected plasma samples from apparently healthy, middle aged men were analysed for coenzyme Q10 (CoQ10), alpha-tocopherol (AT) and free cholesterol (FC) in: 1) whole plasma, 2) the HDL lipoprotein fraction after LDL precipitation (VLDL + LDL). CoQ10, AT and FC in plasma averaged 0.69 +/- .11, 6.7...

journal_title：Annals of medicine

authors： Johansen K,Theorell H,Karlsson J,Diamant B,Folkers K

更新日期：1991-12-01 00:00:00

abstract：:The molecular circadian clock entrains biological rhythms to a 24-hour schedule. Aspects of cardiovascular physiology and, indeed, the incidence of myocardial infarction and stroke are also subject to diurnal variation. The use of rodent models of disrupted clock function has begun to elucidate the role of the molecul...

journal_title：Annals of medicine

authors： Curtis AM,Fitzgerald GA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) is one of the most powerful determinants of cardiovascular risk in women. This risk may differ between post-menopausal women with and without vasomotor hot flushes, possibly indicating different vascular responses to hormone therapy (HT). Thus, we compared in a clinical trial the effect o...

journal_title：Annals of medicine

authors： Tuomikoski P,Haapalahti P,Sarna S,Ylikorkala O,Mikkola TS

更新日期：2010-07-01 00:00:00

abstract：:Exposures of human populations to pesticides and industrial pollutants, and to synthetic chemicals present in foods, beverages, and plastics, have raised concern that these substances can interfere with endogenous sex hormone function. Interference with sex hormone action can, in turn, result in a variety of developme...

journal_title：Annals of medicine

authors： Akingbemi BT,Hardy MP

更新日期：2001-09-01 00:00:00

abstract：:Pancreatic beta-cell dysfunction and insulin resistance are two interrelated defects in the pathophysiology of type 2 diabetes. Defects in peripheral insulin action precede the development of glucose intolerance, as the pancreas compensates for insulin resistance by increasing insulin production and secretion. This ma...

journal_title：Annals of medicine

authors： Sesti G

更新日期：2002-01-01 00:00:00

abstract：:In the past few years diabetes has become the leading cause of end-stage renal disease in all Western countries. A correlation between blood pressure and rate of progression in diabetic nephropathy was noted very early, and increased local activity of the renin angiotensin system was identified as a major pathophysiol...

journal_title：Annals of medicine

authors： Eberhard R,Dikow R

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Multiple lines of evidence suggest that the circadian clock contributes to the pathogenesis of winter depression or seasonal affective disorder (SAD). We hypothesized that sequence variations in three genes, including Per2, Arntl, and Npas2, which form a functional unit at the core of the circadian clock, pr...

journal_title：Annals of medicine

authors： Partonen T,Treutlein J,Alpman A,Frank J,Johansson C,Depner M,Aron L,Rietschel M,Wellek S,Soronen P,Paunio T,Koch A,Chen P,Lathrop M,Adolfsson R,Persson ML,Kasper S,Schalling M,Peltonen L,Schumann G

更新日期：2007-01-01 00:00:00

abstract：:Despite striking extensions of lifespan, leading causes of death in most countries now constitute chronic, degenerative diseases which outpace the capacity of health systems. Cardiovascular disease is the most common cause of death in both developed and undeveloped countries. In America, nearly half of the adult popul...

journal_title：Annals of medicine

authors： Kones R,Rumana U

更新日期：2017-05-01 00:00:00

abstract：:A radioimmunoassay method for endothelin was developed. Antisera raised against endothelin 1 showed significant crossreaction with endothelin 2 and 3 (45 and 13%, respectively). Considerable endothelin immunoreactivity was shown to be present in the cerebrospinal fluid of patients with a subarachnoid hemorrhage, rangi...

journal_title：Annals of medicine

authors： Suzuki H,Sato S,Suzuki Y,Oka M,Tsuchiya T,Iino I,Yamanaka T,Ishihara N,Shimoda S

更新日期：1990-01-01 00:00:00

abstract：:The risk of cardiovascular disease is markedly increased in patients with type 2 diabetes with a prevalence twice as high compared to the background population. With the recognition of multiple concomitant risk factors for both microvascular as well as cardiovascular disease in type 2 diabetic patients, treatment stra...

journal_title：Annals of medicine

authors： Gaede P,Pedersen O

更新日期：2004-01-01 00:00:00