Food allergies: prevalence, molecular characterization, and treatment/prevention strategies.

Abstract:

:A significant proportion of the population is either affected by or concerned about food allergy. Our knowledge about food allergens and how they stimulate the immune system has increased dramatically over the past decade. However, reasons for the increased prevalence of food allergy are not clear. The diagnosis of food allergy requires that the patient and caregivers examine all foods for the presence of potential allergens in order to prevent inadvertent ingestion and further reactions. Fortunately, many children develop tolerance to allergenic foods after a period of dietary elimination. Various immunotherapy approaches are under investigation to alleviate or prevent food-induced reactions in those who have persistent food allergies.

journal_name

Annu Rev Nutr

authors

Lee LA,Burks AW

doi

10.1146/annurev.nutr.26.061505.111211

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

539-65

eissn

0199-9885

issn

1545-4312

journal_volume

26

pub_type

杂志文章,评审
  • Is there a fatty acid taste?

    abstract::Taste is a chemical sense that aids in the detection of nutrients and guides food choice. A limited number of primary qualities comprise taste. Accumulating evidence has raised a question about whether fat should be among them. Most evidence indicates triacylglycerol is not an effective taste stimulus, though it clear...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-080508-141108

    authors: Mattes RD

    更新日期:2009-01-01 00:00:00

  • Protein and amino acid requirements of fishes.

    abstract::Tentative qualitative and quantitative amino acid requirements have been reported for the major species of fish reared for market or as replacement stocks for natural waters. Most work has concentrated upon juvenile fish or upon rapidly growing young market fish; these have high protein dietary requirements (30-50%) t...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nu.06.070186.001301

    authors: Wilson RP

    更新日期:1986-01-01 00:00:00

  • FADS1 and FADS2 Polymorphisms Modulate Fatty Acid Metabolism and Dietary Impact on Health.

    abstract::Variants in the FADS gene cluster modify the activity of polyunsaturated fatty acid (PUFA) desaturation and the lipid composition in human blood and tissue. FADS variants have been associated with plasma lipid concentrations, risk of cardiovascular diseases, overweight, eczema, pregnancy outcomes, and cognitive functi...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-082018-124250

    authors: Koletzko B,Reischl E,Tanjung C,Gonzalez-Casanova I,Ramakrishnan U,Meldrum S,Simmer K,Heinrich J,Demmelmair H

    更新日期:2019-08-21 00:00:00

  • Regulation of selenoproteins.

    abstract::Selenium exerts its biological activity largely through selenoproteins, which contain the element in the form of selenocysteine. Five selenoproteins have been characterized in animal tissues and there is evidence that a number of others exist. Selenoprotein synthesis is a complex process that has been well characteriz...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nu.13.070193.000433

    authors: Burk RF,Hill KE

    更新日期:1993-01-01 00:00:00

  • Nutrition Regulates Innate Immunity in Health and Disease.

    abstract::Nutrient content and nutrient timing are considered key regulators of human health and a variety of diseases and involve complex interactions with the mucosal immune system. In particular, the innate immune system is emerging as an important signaling hub that modulates the response to nutritional signals, in part via...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章

    doi:10.1146/annurev-nutr-120919-094440

    authors: Nobs SP,Zmora N,Elinav E

    更新日期:2020-09-23 00:00:00

  • Single-Subject Studies in Translational Nutrition Research.

    abstract::There is a great deal of interest in personalized, individualized, or precision interventions for disease and health-risk mitigation. This is as true of nutrition-based intervention and prevention strategies as it is for pharmacotherapies and pharmaceutical-oriented prevention strategies. Essentially, technological br...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071816-064717

    authors: Schork NJ,Goetz LH

    更新日期:2017-08-21 00:00:00

  • Regulation of iron metabolism by hepcidin.

    abstract::Hepcidin, a peptide hormone made in the liver, is the principal regulator of systemic iron homeostasis. Hepcidin controls plasma iron concentration and tissue distribution of iron by inhibiting intestinal iron absorption, iron recycling by macrophages, and iron mobilization from hepatic stores. Hepcidin acts by inhibi...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.26.061505.111303

    authors: Nemeth E,Ganz T

    更新日期:2006-01-01 00:00:00

  • Successful weight loss maintenance.

    abstract::Obesity is now recognized as a serious chronic disease, but there is pessimism about how successful treatment can be. A general perception is that almost no one succeeds in long-term maintenance of weight loss. To define long-term weight loss success, we need an accepted definition. We propose defining successful long...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.21.1.323

    authors: Wing RR,Hill JO

    更新日期:2001-01-01 00:00:00

  • Genetic Risk Factors for Folate-Responsive Neural Tube Defects.

    abstract::Neural tube defects (NTDs) are the most severe congenital malformations of the central nervous system. The etiology is complex, with both genetic and environmental factors having important contributions. Researchers have known for the past two decades that maternal periconceptional use of the B vitamin folic acid can ...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071714-034235

    authors: Molloy AM,Pangilinan F,Brody LC

    更新日期:2017-08-21 00:00:00

  • Trans fatty acids and their effects on lipoproteins in humans.

    abstract::Trans fatty acids raise plasma low-density lipoprotein (LDL) cholesterol levels in volunteers when exchanged for cis unsaturated fatty acids in the diet. In addition, trans fatty acids may lower high-density lipoprotein (HDL) cholesterol levels and raise triglyceride and lipoprotein(a) levels in plasma. Trans and cis ...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nu.15.070195.002353

    authors: Katan MB,Zock PL,Mensink RP

    更新日期:1995-01-01 00:00:00

  • Nutritional Requirements for Sustaining Health and Performance During Exposure to Extreme Environments.

    abstract::Dietary guidelines are formulated to meet minimum nutrient requirements, which prevent deficiencies and maintain health, growth, development, and function. These guidelines can be inadequate and contribute to disrupted homeostasis, lean body mass loss, and deteriorated performance in individuals who are working long, ...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章

    doi:10.1146/annurev-nutr-011720-122637

    authors: Pasiakos SM

    更新日期:2020-09-23 00:00:00

  • Variation in the Ability to Taste Bitter Thiourea Compounds: Implications for Food Acceptance, Dietary Intake, and Obesity Risk in Children.

    abstract::The ability to taste bitter thiourea compounds, such as phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP), is inherited. Polymorphisms in the bitter-taste receptor TAS2R38 explain the majority of phenotypic variation in the PROP phenotype. It has been hypothesized that the PROP phenotype is a marker for percep...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071715-050916

    authors: Keller KL,Adise S

    更新日期:2016-07-17 00:00:00

  • The role of vitamin A in mammalian reproduction and embryonic development.

    abstract::Since the late 1980s, there has been an explosion of information on the molecular mechanisms and functions of vitamin A. This review focuses on the essential role of vitamin A in female reproduction and embryonic development and the metabolism of vitamin A (retinol) that results in these functions. Evidence strongly s...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.22.010402.102745E

    authors: Clagett-Dame M,DeLuca HF

    更新日期:2002-01-01 00:00:00

  • Different approaches to define individual amino acid requirements.

    abstract::A full review of the strengths and limitations of the various methods used to define amino acid requirements is provided. The focus is on the recent development of carbon oxidation techniques such as indicator amino acid oxidation and 24-h amino acid balance to determine dietary indispensable (essential) amino acid ne...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.23.011702.073247

    authors: Pencharz PB,Ball RO

    更新日期:2003-01-01 00:00:00

  • What are the risks and benefits to increasing dietary bone minerals and vitamin D intake in infants and small children?

    abstract::Bone minerals and vitamin D are crucial for infants and small children. Human milk has little vitamin D, and supplemental vitamin D must be given to all infants either via drops or as contained in infant formula or foods. The calcium and phosphorus in human milk are adequate for infants in the first six months of life...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-072610-145216

    authors: Abrams SA

    更新日期:2011-08-21 00:00:00

  • Nutrient-Gene Interaction in Colon Cancer, from the Membrane to Cellular Physiology.

    abstract::The International Agency for Research on Cancer recently released an assessment classifying red and processed meat as "carcinogenic to humans" on the basis of the positive association between increased consumption and risk for colorectal cancer. Diet, however, can also decrease the risk for colorectal cancer and be us...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071715-051039

    authors: Hou TY,Davidson LA,Kim E,Fan YY,Fuentes NR,Triff K,Chapkin RS

    更新日期:2016-07-17 00:00:00

  • The cholesterol-raising factor from coffee beans.

    abstract::Some coffee brewing techniques raise the serum concentration of total and low-density-lipoprotein cholesterol in humans, whereas others do not. The responsible factors are the diterpene lipids cafestol and kahweol, which make up about 1% (wt:wt) of coffee beans. Diterpenes are extracted by hot water but are retained b...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.17.1.305

    authors: Urgert R,Katan MB

    更新日期:1997-01-01 00:00:00

  • Micronutrients, birth weight, and survival.

    abstract::Maternal micronutrient requirements during pregnancy increase to meet the physiologic changes in gestation and fetal demands for growth and development. Maternal micronutrient deficiencies are high and coexist in many settings, likely influencing birth and newborn outcomes. The only recommendation for pregnancy curren...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.012809.104813

    authors: Christian P

    更新日期:2010-08-21 00:00:00

  • Vitamin E in humans: demand and delivery.

    abstract::How much vitamin E is enough? An established use of supplemental vitamin E in humans is in the prevention and therapy of deficiency symptoms. The cause of vitamin E deficiency, characterized by peripheral neuropathy and ataxia, is usually malabsorption-a result of fat malabsorption or genetic abnormalities in lipoprot...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nu.16.070196.001541

    authors: Traber MG,Sies H

    更新日期:1996-01-01 00:00:00

  • Regulation of iron metabolism: translational effects mediated by iron, heme, and cytokines.

    abstract::Recent advances in the knowledge of iron metabolism underscore its complex relationship to overall cell metabolism. One of the key components of the iron uptake and storage pathway is ferritin, a protein that sequesters iron in a nontoxic form. Ferritin synthesis is translationally regulated by iron. Molecules such as...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nu.15.070195.001323

    authors: Mascotti DP,Rup D,Thach RE

    更新日期:1995-01-01 00:00:00

  • Polyunsaturated fatty acid regulation of genes of lipid metabolism.

    abstract::Apart from being an important macronutrient, dietary fat has recently gained much prominence for its role in regulating gene expression. Polyunsaturated fatty acids (PUFAs) affect gene expression through various mechanisms including, but not limited to, changes in membrane composition, intracellular calcium levels, an...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.25.051804.101917

    authors: Sampath H,Ntambi JM

    更新日期:2005-01-01 00:00:00

  • ALCOHOL: its metabolism and interaction with nutrients.

    abstract::In the past, alcoholic liver disease was attributed exclusively to dietary deficiencies, but experimental and judicious clinical studies have now established alcohol's hepatotoxicity. Despite an adequate diet, it can contribute to the entire spectrum of liver diseases, mainly by generating oxidative stress through its...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.20.1.395

    authors: Lieber CS

    更新日期:2000-01-01 00:00:00

  • The impact of nutrition on thyroid hormone physiology and action.

    abstract::In summary, nutritionally directed alterations in thyroid hormone metabolism appear to be adaptive and to serve important protective roles in the overall economy of the body. These adjustments to nutrition are found at practically every level of thyroid regulation, beginning in the CNS and ending with the final action...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nu.09.070189.001221

    authors: Danforth E Jr,Burger AG

    更新日期:1989-01-01 00:00:00

  • Association of maternal obesity before conception with poor lactation performance.

    abstract::The objective of this review is to evaluate the evidence for a link between maternal obesity and poor lactation performance. In nonhuman species, excess maternal fatness is deleterious for lactation and also for maternal health and survival. These effects occur during pregnancy and as milk production is beginning. The...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.27.061406.093738

    authors: Rasmussen KM

    更新日期:2007-01-01 00:00:00

  • Vitamin E deficiency and neurologic disease.

    abstract::During the recent resurgence of interest in the clinical uses of vitamin E, one of the major foci of attention has been the neurologic role of vitamin E in humans. Studies in patients with secondary vitamin E deficiency, caused by fat malabsorption disorders and total parenteral nutrition lacking an adequate supply of...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nu.08.070188.002031

    authors: Sokol RJ

    更新日期:1988-01-01 00:00:00

  • Iatrogenic nutritional deficiencies.

    abstract::This article catalogs the nutritional deficiencies inadvertently introduced by certain treatment regimens. Specifically, the iatrogenic effects on nutrition of surgery, hemodialysis, irradiation, and drugs are reviewed. Nutritional problems are particularly frequent consequences of surgery on the gastrointestinal tr...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nu.02.070182.001221

    authors: Young RC,Blass JP

    更新日期:1982-01-01 00:00:00

  • Quantifying diet for nutrigenomic studies.

    abstract::The field of nutrigenomics shows tremendous promise for improved understanding of the effects of dietary intake on health. The knowledge that metabolic pathways may be altered in individuals with genetic variants in the presence of certain dietary exposures offers great potential for personalized nutrition advice. How...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-072610-145203

    authors: Tucker KL,Smith CE,Lai CQ,Ordovas JM

    更新日期:2013-01-01 00:00:00

  • Regulation of mammalian acetyl-coenzyme A carboxylase.

    abstract::Long-chain fatty acids are involved in all aspects of cellular structure and function. For controlling amounts of fatty acids, cells are endowed with two acetyl-coenzyme A carboxylase (ACC) systems. ACC-alpha is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC-beta is believed to control m...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.17.1.77

    authors: Kim KH

    更新日期:1997-01-01 00:00:00

  • Regulation of lipolysis in adipocytes.

    abstract::Lipolysis of white adipose tissue triacylglycerol stores results in the liberation of glycerol and nonesterified fatty acids that are released into the vasculature for use by other organs as energy substrates. In response to changes in nutritional state, lipolysis rates are precisely regulated through hormonal and bio...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.27.061406.093734

    authors: Duncan RE,Ahmadian M,Jaworski K,Sarkadi-Nagy E,Sul HS

    更新日期:2007-01-01 00:00:00

  • Role of dietary proteins and amino acids in the pathogenesis of insulin resistance.

    abstract::Dietary proteins and amino acids are important modulators of glucose metabolism and insulin sensitivity. Although high intake of dietary proteins has positive effects on energy homeostasis by inducing satiety and possibly increasing energy expenditure, it has detrimental effects on glucose homeostasis by promoting ins...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.25.050304.092545

    authors: Tremblay F,Lavigne C,Jacques H,Marette A

    更新日期:2007-01-01 00:00:00