Mechanisms of digestion and absorption of dietary vitamin A.

abstract：:Birth and adaptation to extrauterine life involve major shifts in the protein and energy metabolism of the human newborn. These include a shift from a state of continuous supply of nutrients including amino acids from the mother to cyclic periodic oral intake, a change in the redox state of organs, thermogenesis, and ...

journal_title：Annual review of nutrition

authors： Kalhan SC,Bier DM

更新日期：2008-01-01 00:00:00

abstract：:Variants in the FADS gene cluster modify the activity of polyunsaturated fatty acid (PUFA) desaturation and the lipid composition in human blood and tissue. FADS variants have been associated with plasma lipid concentrations, risk of cardiovascular diseases, overweight, eczema, pregnancy outcomes, and cognitive functi...

journal_title：Annual review of nutrition

authors： Koletzko B,Reischl E,Tanjung C,Gonzalez-Casanova I,Ramakrishnan U,Meldrum S,Simmer K,Heinrich J,Demmelmair H

更新日期：2019-08-21 00:00:00

abstract：:The health benefits of pre- and probiotics have been the subject of increased research interests. These food supplements have been demonstrated to alter the pre-existing intestinal flora so as to provide an advantage to the host. This review focuses on the scientific evidence both for and against their role in promoti...

journal_title：Annual review of nutrition

authors： Teitelbaum JE,Walker WA

更新日期：2002-01-01 00:00:00

abstract：:Glucose is an essential nutrient for the human body. It is the major energy source for many cells, which depend on the bloodstream for a steady supply. Blood glucose levels, therefore, are carefully maintained. The liver plays a central role in this process by balancing the uptake and storage of glucose via glycogenes...

journal_title：Annual review of nutrition

authors： Nordlie RC,Foster JD,Lange AJ

更新日期：1999-01-01 00:00:00

abstract：:It appears that specific functions may be assigned to some of the cellular folate binding proteins with some degree of certainty. Those that are membrane bound or derived from membranes probably have a role in transport of folate molecules into the cell. This is in spite of the fact that the localization of this prote...

journal_title：Annual review of nutrition

authors： Wagner C

更新日期：1982-01-01 00:00:00

abstract：:Hypoxia develops in white adipose tissue in obese mice, resulting in changes in adipocyte function that may underpin the dysregulation that leads to obesity-associated disorders. Whether hypoxia occurs in adipose tissue in human obesity is unclear, with recent studies contradicting earlier reports that this was the ca...

journal_title：Annual review of nutrition

authors： Trayhurn P

更新日期：2014-01-01 00:00:00

abstract：:Identifying bioactive compounds and establishing their health effects are active areas of scientific inquiry. There are exciting prospects that select bioactive compounds will reduce the risk of many diseases, including chronic diseases such as cardiovascular disease. Recent findings have established that cardiovascul...

journal_title：Annual review of nutrition

authors： Kris-Etherton PM,Lefevre M,Beecher GR,Gross MD,Keen CL,Etherton TD

更新日期：2004-01-01 00:00:00

abstract：:The discovery of multiple selenoproteins has raised tantalizing questions about their role in maintaining normal cellular function. Unfortunately, many of these remain inadequately investigated. While they have a role in maintaining redox balance, other functions are becoming increasingly recognized. As the roles of t...

journal_title：Annual review of nutrition

authors： Davis CD,Tsuji PA,Milner JA

更新日期：2012-08-21 00:00:00

abstract：:Emerging evidence suggests that ascorbate, the dominant form of vitamin C under physiological pH conditions, influences activity of the genome via regulating epigenomic processes. Ascorbate serves as a cofactor for Ten-eleven translocation (TET) dioxygenases that catalyze the oxidation of 5-methylcytosine (5mC) into 5...

journal_title：Annual review of nutrition

authors： Young JI,Züchner S,Wang G

更新日期：2015-01-01 00:00:00

abstract：:Maternal micronutrient requirements during pregnancy increase to meet the physiologic changes in gestation and fetal demands for growth and development. Maternal micronutrient deficiencies are high and coexist in many settings, likely influencing birth and newborn outcomes. The only recommendation for pregnancy curren...

journal_title：Annual review of nutrition

authors： Christian P

更新日期：2010-08-21 00:00:00

abstract：:Hepcidin, a peptide hormone made in the liver, is the principal regulator of systemic iron homeostasis. Hepcidin controls plasma iron concentration and tissue distribution of iron by inhibiting intestinal iron absorption, iron recycling by macrophages, and iron mobilization from hepatic stores. Hepcidin acts by inhibi...

journal_title：Annual review of nutrition

authors： Nemeth E,Ganz T

更新日期：2006-01-01 00:00:00

abstract：:Epidemiologic and experimental evidence reviewed in this article emphasizes the complex and multifactorial etiology of endemic goiter. The important role of iodine deficiency as an etiologic factor in endemic goiter is firmly established, but there is evidence that other environmental factors can play an equally impor...

journal_title：Annual review of nutrition

authors： Gaitan E

更新日期：1990-01-01 00:00:00

abstract：:Since the late 1980s, there has been an explosion of information on the molecular mechanisms and functions of vitamin A. This review focuses on the essential role of vitamin A in female reproduction and embryonic development and the metabolism of vitamin A (retinol) that results in these functions. Evidence strongly s...

journal_title：Annual review of nutrition

authors： Clagett-Dame M,DeLuca HF

更新日期：2002-01-01 00:00:00

abstract：:The effects of saturated fatty acids (SFAs) on cardiovascular disease (CVD) risk are modulated by the nutrients that replace them and their food matrices. Replacement of SFAs with polyunsaturated fatty acids has been associated with reduced CVD risk, although there is heterogeneity in both fatty acid categories. In co...

journal_title：Annual review of nutrition

authors： Siri-Tarino PW,Chiu S,Bergeron N,Krauss RM

更新日期：2015-01-01 00:00:00

abstract：:This article catalogs the nutritional deficiencies inadvertently introduced by certain treatment regimens. Specifically, the iatrogenic effects on nutrition of surgery, hemodialysis, irradiation, and drugs are reviewed. Nutritional problems are particularly frequent consequences of surgery on the gastrointestinal tr...

journal_title：Annual review of nutrition

authors： Young RC,Blass JP

更新日期：1982-01-01 00:00:00

abstract：:During the recent resurgence of interest in the clinical uses of vitamin E, one of the major foci of attention has been the neurologic role of vitamin E in humans. Studies in patients with secondary vitamin E deficiency, caused by fat malabsorption disorders and total parenteral nutrition lacking an adequate supply of...

journal_title：Annual review of nutrition

authors： Sokol RJ

更新日期：1988-01-01 00:00:00

abstract：:The ability to taste bitter thiourea compounds, such as phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP), is inherited. Polymorphisms in the bitter-taste receptor TAS2R38 explain the majority of phenotypic variation in the PROP phenotype. It has been hypothesized that the PROP phenotype is a marker for percep...

journal_title：Annual review of nutrition

authors： Keller KL,Adise S

更新日期：2016-07-17 00:00:00

abstract：:The "fetal origins" hypothesis postulates that conditions, most likely nutritional, "program" the fetus for the development of chronic diseases in adulthood. Associations between the newborn's size at birth and various determinants or consequences of chronic diseases have been identified in many, but not all, of the a...

journal_title：Annual review of nutrition

authors： Rasmussen KM

更新日期：2001-01-01 00:00:00

abstract：:Some coffee brewing techniques raise the serum concentration of total and low-density-lipoprotein cholesterol in humans, whereas others do not. The responsible factors are the diterpene lipids cafestol and kahweol, which make up about 1% (wt:wt) of coffee beans. Diterpenes are extracted by hot water but are retained b...

journal_title：Annual review of nutrition

authors： Urgert R,Katan MB

更新日期：1997-01-01 00:00:00

abstract：:Caloric restriction (CR), the consumption of fewer calories without malnutrition, and reduced insulin and/or IGFI receptor signaling delay many age-related physiological changes and extend the lifespan of many model organisms. Here, we present and review microarray and biochemical studies indicating that the potent an...

journal_title：Annual review of nutrition

authors： Spindler SR,Dhahbi JM

更新日期：2007-01-01 00:00:00

abstract：:Investigations into regulating metabolic pathways with stable isotopes have, over the past decade, undergone major development with the use of nuclear magnetic resonance and mass spectrometry in studying labeling patterns of newly synthesized biomolecules. In this review, we concentrate on investigations of mass isoto...

journal_title：Annual review of nutrition

authors： Brunengraber H,Kelleher JK,Des Rosiers C

更新日期：1997-01-01 00:00:00

abstract：:Obesity is now recognized as a serious chronic disease, but there is pessimism about how successful treatment can be. A general perception is that almost no one succeeds in long-term maintenance of weight loss. To define long-term weight loss success, we need an accepted definition. We propose defining successful long...

journal_title：Annual review of nutrition

authors： Wing RR,Hill JO

更新日期：2001-01-01 00:00:00

abstract：:Dietary proteins and amino acids are important modulators of glucose metabolism and insulin sensitivity. Although high intake of dietary proteins has positive effects on energy homeostasis by inducing satiety and possibly increasing energy expenditure, it has detrimental effects on glucose homeostasis by promoting ins...

journal_title：Annual review of nutrition

authors： Tremblay F,Lavigne C,Jacques H,Marette A

更新日期：2007-01-01 00:00:00

abstract：:It is clear that many diseases are known to involve defects in vitamin B6 metabolism, but that even more await definitive studies. Furthermore, some functions of vitamin B6, such as its role in glucocorticoid action (21), have been discovered so recently that the medical implications have not yet been fully explored. ...

journal_title：Annual review of nutrition

authors： Merrill AH Jr,Henderson JM

更新日期：1987-01-01 00:00:00

abstract：:Vitamin D deficiency is prevalent throughout the world, and growing evidence supports a requirement for optimal vitamin D levels for the healthy developing and adult brain. Vitamin D has important roles in proliferation and differentiation, calcium signaling within the brain, and neurotrophic and neuroprotective actio...

journal_title：Annual review of nutrition

authors： Groves NJ,McGrath JJ,Burne TH

更新日期：2014-01-01 00:00:00

abstract：:Lipolysis of white adipose tissue triacylglycerol stores results in the liberation of glycerol and nonesterified fatty acids that are released into the vasculature for use by other organs as energy substrates. In response to changes in nutritional state, lipolysis rates are precisely regulated through hormonal and bio...

journal_title：Annual review of nutrition

authors： Duncan RE,Ahmadian M,Jaworski K,Sarkadi-Nagy E,Sul HS

更新日期：2007-01-01 00:00:00

abstract：:Taste is a chemical sense that aids in the detection of nutrients and guides food choice. A limited number of primary qualities comprise taste. Accumulating evidence has raised a question about whether fat should be among them. Most evidence indicates triacylglycerol is not an effective taste stimulus, though it clear...

journal_title：Annual review of nutrition

authors： Mattes RD

更新日期：2009-01-01 00:00:00

abstract：:Tentative qualitative and quantitative amino acid requirements have been reported for the major species of fish reared for market or as replacement stocks for natural waters. Most work has concentrated upon juvenile fish or upon rapidly growing young market fish; these have high protein dietary requirements (30-50%) t...

journal_title：Annual review of nutrition

authors： Wilson RP

更新日期：1986-01-01 00:00:00

abstract：:The biosynthesis of one riboflavin molecule requires one molecule of GTP and two molecules of ribulose 5-phosphate as substrates. The imidazole ring of GTP is hydrolytically opened, yielding a 4, 5-diaminopyrimidine which is converted to 5-amino-6-ribitylamino-2, 4(1H,3H)-pyrimidinedione by a sequence of deamination, ...

journal_title：Annual review of nutrition

authors： Bacher A,Eberhardt S,Fischer M,Kis K,Richter G

更新日期：2000-01-01 00:00:00

abstract：:Calcium requirements may vary throughout the lifespan. During the growth years and up to age 25-30, it is important to maximize dietary intake of calcium to maintain positive calcium balance and achieve peak bone mass, thereby possibly decreasing the risk of fracture when bone is subsequently lost. The RDA for age 10-...

journal_title：Annual review of nutrition

authors： Arnaud CD,Sanchez SD

更新日期：1990-01-01 00:00:00