Is there a fatty acid taste?

abstract：:Much of the science underlying nutrition has come from biochemical studies. This certainly is true in our understanding of the metabolism and function of such micronutrient cofactors as vitamins and metal ions. My own interest stems from an early desire to understand the molecular events in an organism and ultimately ...

journal_title：Annual review of nutrition

authors： McCormick DB

更新日期：2004-01-01 00:00:00

abstract：:Trans fatty acids raise plasma low-density lipoprotein (LDL) cholesterol levels in volunteers when exchanged for cis unsaturated fatty acids in the diet. In addition, trans fatty acids may lower high-density lipoprotein (HDL) cholesterol levels and raise triglyceride and lipoprotein(a) levels in plasma. Trans and cis ...

journal_title：Annual review of nutrition

authors： Katan MB,Zock PL,Mensink RP

更新日期：1995-01-01 00:00:00

abstract：:Research on human milk oligosaccharides (HMOs) has received much attention in recent years. However, it started about a century ago with the observation that oligosaccharides might be growth factors for a so-called bifidus flora in breast-fed infants and extends to the recent finding of cell adhesion molecules in huma...

journal_title：Annual review of nutrition

authors： Kunz C,Rudloff S,Baier W,Klein N,Strobel S

更新日期：2000-01-01 00:00:00

abstract：:The discovery of multiple selenoproteins has raised tantalizing questions about their role in maintaining normal cellular function. Unfortunately, many of these remain inadequately investigated. While they have a role in maintaining redox balance, other functions are becoming increasingly recognized. As the roles of t...

journal_title：Annual review of nutrition

authors： Davis CD,Tsuji PA,Milner JA

更新日期：2012-08-21 00:00:00

abstract：:Fatty acid-binding proteins (FABPs) are abundant intracellular proteins that bind long-chain fatty acids with high affinity. Nine separate mammalian FABPs have been identified, and their tertiary structures are highly conserved. The FABPs have unique tissue-specific distributions that have long suggested functional di...

journal_title：Annual review of nutrition

authors： Storch J,Corsico B

更新日期：2008-01-01 00:00:00

abstract：:Iron deficiency in early life is associated with delayed development as assessed by a number of clinical trials using similar global scales of development; this poor development during infancy persists in most cases after iron therapy has corrected iron status. If iron deficiency occurs in preschool and older children...

journal_title：Annual review of nutrition

authors： Beard JL,Connor JR

更新日期：2003-01-01 00:00:00

abstract：:High sugar intake may increase cancer risk by promoting insulin-glucose dysregulation, oxidative stress, inflammation, and body adiposity, but epidemiologic evidence is unclear. Associations between dietary sugars and lifestyle-related cancer risk from longitudinal studies were evaluated. We systematically searched Pu...

journal_title：Annual review of nutrition

authors： Makarem N,Bandera EV,Nicholson JM,Parekh N

更新日期：2018-08-21 00:00:00

abstract：:Hypoxia develops in white adipose tissue in obese mice, resulting in changes in adipocyte function that may underpin the dysregulation that leads to obesity-associated disorders. Whether hypoxia occurs in adipose tissue in human obesity is unclear, with recent studies contradicting earlier reports that this was the ca...

journal_title：Annual review of nutrition

authors： Trayhurn P

更新日期：2014-01-01 00:00:00

abstract：:Identifying bioactive compounds and establishing their health effects are active areas of scientific inquiry. There are exciting prospects that select bioactive compounds will reduce the risk of many diseases, including chronic diseases such as cardiovascular disease. Recent findings have established that cardiovascul...

journal_title：Annual review of nutrition

authors： Kris-Etherton PM,Lefevre M,Beecher GR,Gross MD,Keen CL,Etherton TD

更新日期：2004-01-01 00:00:00

abstract：:Recent advances in the knowledge of iron metabolism underscore its complex relationship to overall cell metabolism. One of the key components of the iron uptake and storage pathway is ferritin, a protein that sequesters iron in a nontoxic form. Ferritin synthesis is translationally regulated by iron. Molecules such as...

journal_title：Annual review of nutrition

authors： Mascotti DP,Rup D,Thach RE

更新日期：1995-01-01 00:00:00

abstract：:A full review of the strengths and limitations of the various methods used to define amino acid requirements is provided. The focus is on the recent development of carbon oxidation techniques such as indicator amino acid oxidation and 24-h amino acid balance to determine dietary indispensable (essential) amino acid ne...

journal_title：Annual review of nutrition

authors： Pencharz PB,Ball RO

更新日期：2003-01-01 00:00:00

abstract：:It is clear that many diseases are known to involve defects in vitamin B6 metabolism, but that even more await definitive studies. Furthermore, some functions of vitamin B6, such as its role in glucocorticoid action (21), have been discovered so recently that the medical implications have not yet been fully explored. ...

journal_title：Annual review of nutrition

authors： Merrill AH Jr,Henderson JM

更新日期：1987-01-01 00:00:00

abstract：:This review examines the involvement of the gastrointestinal tract in the utilization of nitrogen, the identities of the nitrogenous substances entering and leaving the gut, and the significance of this recycling in the overall nitrogen economy of the body. It is concerned with nonruminant mammals, including man. ...

journal_title：Annual review of nutrition

authors： Fuller MF,Reeds PJ

更新日期：1998-01-01 00:00:00

abstract：:The field of nutrigenomics shows tremendous promise for improved understanding of the effects of dietary intake on health. The knowledge that metabolic pathways may be altered in individuals with genetic variants in the presence of certain dietary exposures offers great potential for personalized nutrition advice. How...

journal_title：Annual review of nutrition

authors： Tucker KL,Smith CE,Lai CQ,Ordovas JM

更新日期：2013-01-01 00:00:00

abstract：:Oxidative stress is implicated in the pathogenesis of several viral infections, including hepatitis, influenza, and AIDS. Dietary oxidative stress due to either selenium or vitamin E deficiency increases cardiac damage in mice infected with a myocarditic strain of coxsackievirus B3. Such dietary oxidative stress also ...

journal_title：Annual review of nutrition

authors： Beck MA,Levander OA

更新日期：1998-01-01 00:00:00

abstract：:In the past, alcoholic liver disease was attributed exclusively to dietary deficiencies, but experimental and judicious clinical studies have now established alcohol's hepatotoxicity. Despite an adequate diet, it can contribute to the entire spectrum of liver diseases, mainly by generating oxidative stress through its...

journal_title：Annual review of nutrition

authors： Lieber CS

更新日期：2000-01-01 00:00:00

abstract：:Tentative qualitative and quantitative amino acid requirements have been reported for the major species of fish reared for market or as replacement stocks for natural waters. Most work has concentrated upon juvenile fish or upon rapidly growing young market fish; these have high protein dietary requirements (30-50%) t...

journal_title：Annual review of nutrition

authors： Wilson RP

更新日期：1986-01-01 00:00:00

abstract：:There is a growing view that certain foods, particularly those high in refined sugars and fats, are addictive and that some forms of obesity can usefully be treated as a food addiction. This perspective is supported by a growing body of neuroscience research demonstrating that the chronic consumption of energy-dense f...

journal_title：Annual review of nutrition

authors： Carter A,Hendrikse J,Lee N,Yücel M,Verdejo-Garcia A,Andrews ZB,Hall W

更新日期：2016-07-17 00:00:00

abstract：:Selenium exerts its biological activity largely through selenoproteins, which contain the element in the form of selenocysteine. Five selenoproteins have been characterized in animal tissues and there is evidence that a number of others exist. Selenoprotein synthesis is a complex process that has been well characteriz...

journal_title：Annual review of nutrition

authors： Burk RF,Hill KE

更新日期：1993-01-01 00:00:00

abstract：:Since the late 1980s, there has been an explosion of information on the molecular mechanisms and functions of vitamin A. This review focuses on the essential role of vitamin A in female reproduction and embryonic development and the metabolism of vitamin A (retinol) that results in these functions. Evidence strongly s...

journal_title：Annual review of nutrition

authors： Clagett-Dame M,DeLuca HF

更新日期：2002-01-01 00:00:00

abstract：:Apart from being an important macronutrient, dietary fat has recently gained much prominence for its role in regulating gene expression. Polyunsaturated fatty acids (PUFAs) affect gene expression through various mechanisms including, but not limited to, changes in membrane composition, intracellular calcium levels, an...

journal_title：Annual review of nutrition

authors： Sampath H,Ntambi JM

更新日期：2005-01-01 00:00:00

abstract：:The objective of this review is to evaluate the evidence for a link between maternal obesity and poor lactation performance. In nonhuman species, excess maternal fatness is deleterious for lactation and also for maternal health and survival. These effects occur during pregnancy and as milk production is beginning. The...

journal_title：Annual review of nutrition

authors： Rasmussen KM

更新日期：2007-01-01 00:00:00

abstract：:Maternal micronutrient requirements during pregnancy increase to meet the physiologic changes in gestation and fetal demands for growth and development. Maternal micronutrient deficiencies are high and coexist in many settings, likely influencing birth and newborn outcomes. The only recommendation for pregnancy curren...

journal_title：Annual review of nutrition

authors： Christian P

更新日期：2010-08-21 00:00:00

abstract：:The ability to taste bitter thiourea compounds, such as phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP), is inherited. Polymorphisms in the bitter-taste receptor TAS2R38 explain the majority of phenotypic variation in the PROP phenotype. It has been hypothesized that the PROP phenotype is a marker for percep...

journal_title：Annual review of nutrition

authors： Keller KL,Adise S

更新日期：2016-07-17 00:00:00

abstract：:Nutrient content and nutrient timing are considered key regulators of human health and a variety of diseases and involve complex interactions with the mucosal immune system. In particular, the innate immune system is emerging as an important signaling hub that modulates the response to nutritional signals, in part via...

journal_title：Annual review of nutrition

authors： Nobs SP,Zmora N,Elinav E

更新日期：2020-09-23 00:00:00

abstract：:Calcium requirements may vary throughout the lifespan. During the growth years and up to age 25-30, it is important to maximize dietary intake of calcium to maintain positive calcium balance and achieve peak bone mass, thereby possibly decreasing the risk of fracture when bone is subsequently lost. The RDA for age 10-...

journal_title：Annual review of nutrition

authors： Arnaud CD,Sanchez SD

更新日期：1990-01-01 00:00:00

abstract：:Some coffee brewing techniques raise the serum concentration of total and low-density-lipoprotein cholesterol in humans, whereas others do not. The responsible factors are the diterpene lipids cafestol and kahweol, which make up about 1% (wt:wt) of coffee beans. Diterpenes are extracted by hot water but are retained b...

journal_title：Annual review of nutrition

authors： Urgert R,Katan MB

更新日期：1997-01-01 00:00:00

abstract：:The "fetal origins" hypothesis postulates that conditions, most likely nutritional, "program" the fetus for the development of chronic diseases in adulthood. Associations between the newborn's size at birth and various determinants or consequences of chronic diseases have been identified in many, but not all, of the a...

journal_title：Annual review of nutrition

authors： Rasmussen KM

更新日期：2001-01-01 00:00:00

abstract：:Long-chain fatty acids are involved in all aspects of cellular structure and function. For controlling amounts of fatty acids, cells are endowed with two acetyl-coenzyme A carboxylase (ACC) systems. ACC-alpha is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC-beta is believed to control m...

journal_title：Annual review of nutrition

authors： Kim KH

更新日期：1997-01-01 00:00:00

abstract：:Neural tube defects (NTDs) are the most severe congenital malformations of the central nervous system. The etiology is complex, with both genetic and environmental factors having important contributions. Researchers have known for the past two decades that maternal periconceptional use of the B vitamin folic acid can ...

journal_title：Annual review of nutrition

authors： Molloy AM,Pangilinan F,Brody LC

更新日期：2017-08-21 00:00:00