Education Research: Online Alzheimer education for high school and college students: A randomized controlled trial.

abstract：OBJECTIVE:To investigate the role of multiple distributed brain networks, including the default mode, fronto-temporo-parietal, and cingulo-opercular networks, which mediate domain-general and task-specific processes during speech production after aphasic stroke. METHODS:We conducted an observational functional MRI stu...

journal_title：Neurology

authors： Geranmayeh F,Leech R,Wise RJS

更新日期：2016-04-05 00:00:00

abstract：:Four prolonged episodes of partial complex status epilepticus were observed in a teenaged girl. During each there was an "ictal" phase, in which her mental state frequently fluctuated between mildly clouded consciousness and almost total unresponsiveness; once, she was also blind during this phase of impaired consciou...

journal_title：Neurology

authors： Engel J Jr,Ludwig BI,Fetell M

更新日期：1978-09-01 00:00:00

abstract：:We report a Jewish family of Yemenite origin in which three brothers born from a consanguineous marriage had juvenile parkinsonism. The DNA samples from three affected brothers and one healthy brother were analyzed for the linkage to markers covering the autosomal-recessive juvenile parkinsonism (AR-JP) locus. A perfe...

journal_title：Neurology

authors： Nisipeanu P,Inzelberg R,Blumen SC,Carasso RL,Hattori N,Matsumine H,Mizuno Y

更新日期：1999-10-22 00:00:00

abstract：OBJECTIVE:To assess the effects of levodopa on resting-state brain metabolism in PD. BACKGROUND:In previous studies the authors used [18F] fluorodeoxyglucose (FDG) and PET to quantify regional metabolic abnormalities in PD. They found that this disease is characterized reproducibly by a specific abnormal PD-related pa...

journal_title：Neurology

authors： Feigin A,Fukuda M,Dhawan V,Przedborski S,Jackson-Lewis V,Mentis MJ,Moeller JR,Eidelberg D

更新日期：2001-12-11 00:00:00

abstract：OBJECTIVE:To characterize a brainstem location specific to coma-causing lesions, and its functional connectivity network. METHODS:We compared 12 coma-causing brainstem lesions to 24 control brainstem lesions using voxel-based lesion-symptom mapping in a case-control design to identify a site significantly associated w...

journal_title：Neurology

authors： Fischer DB,Boes AD,Demertzi A,Evrard HC,Laureys S,Edlow BL,Liu H,Saper CB,Pascual-Leone A,Fox MD,Geerling JC

更新日期：2016-12-06 00:00:00

abstract：OBJECTIVE:To compare access to caregiving between men and women with Parkinson disease (PD). METHODS:This was a cross-sectional and longitudinal study among participants with PD enrolled in the National Parkinson Foundation Parkinson's Outcomes Project from 2009 to 2014 at 21 international sites. The primary outcome m...

journal_title：Neurology

authors： Dahodwala N,Shah K,He Y,Wu SS,Schmidt P,Cubillos F,Willis AW

更新日期：2018-01-02 00:00:00

abstract：:Using PET with the opioidergic ligand [11C]diprenorphine, the authors demonstrate decreased tracer binding in the pineal gland of cluster headache patients vs healthy volunteers. Opioid receptor availability in the hypothalamus and cingulate cortex depended on the duration of the headache disorder. Therefore, the path...

journal_title：Neurology

authors： Sprenger T,Willoch F,Miederer M,Schindler F,Valet M,Berthele A,Spilker ME,Förderreuther S,Straube A,Stangier I,Wester HJ,Tölle TR

更新日期：2006-04-11 00:00:00

abstract：:A woman with typical features of myoclonic epilepsy with ragged red fibers (MERRF) had a novel heteroplasmic mutation (G611A) in the mitochondrial DNA tRNA phenylalanine gene. The mutation was heteroplasmic (91%) in muscle but undetectable in accessible tissues from the patient and her maternal relatives. Single-fiber...

journal_title：Neurology

authors： Mancuso M,Filosto M,Mootha VK,Rocchi A,Pistolesi S,Murri L,DiMauro S,Siciliano G

更新日期：2004-06-08 00:00:00

abstract：:The authors assessed the referral pattern and outcome in patients with Guillain-Barré syndrome (n = 266) after the introduction of intravenous immunoglobulin (IVIg). Fewer patients were transferred from small to large hospitals after the introduction of IVIg (p = 0.05). This did not result in a worse outcome in patien...

journal_title：Neurology

authors： Van Koningsveld R,Van Doorn PA,Schmitz PI,Van der Meché FG

更新日期：2001-02-27 00:00:00

abstract：BACKGROUND:Transcranial contrast Doppler studies have shown an increased prevalence of right-to-left shunts in patients with migraine with aura compared with controls. The anatomy and size of these right-to-left shunts have never been directly assessed. METHODS:In a cross-sectional case-control study, the authors perf...

journal_title：Neurology

authors： Schwerzmann M,Nedeltchev K,Lagger F,Mattle HP,Windecker S,Meier B,Seiler C

更新日期：2005-11-08 00:00:00

abstract：OBJECTIVE:To test the accuracy of an equation in adult patients with status epilepticus that calculates the free concentration of serum valproic acid (fVPA) from the total concentration of serum valproic acid (tVPA) and serum albumin. METHODS:All adult patients with status epilepticus who were treated at a Swiss acade...

journal_title：Neurology

authors： Fisch U,Baumann SM,Semmlack S,Marsch S,Rüegg S,Sutter R

更新日期：2021-01-05 00:00:00

abstract：OBJECTIVES:To estimate the risk to public safety posed by drivers with epilepsy, the authors compared annual totals and disease-specific risk for fatal crashes associated with seizures and other medical conditions. They compared individual risks for fatal crashes due to seizures and other causes of mortality in patient...

journal_title：Neurology

authors： Sheth SG,Krauss G,Krumholz A,Li G

更新日期：2004-09-28 00:00:00

abstract：OBJECTIVE:To determine, in a cross-sectional evaluation of nondemented individuals, if age-related memory decline is influenced by apolipoprotein E (apoE) genotype. BACKGROUND:The apoE-4 allele is an important risk factor for AD. PET in cognitively normal apoE-4 carriers (mean age, 56 years) shows reduced cerebral met...

journal_title：Neurology

authors： Caselli RJ,Graff-Radford NR,Reiman EM,Weaver A,Osborne D,Lucas J,Uecker A,Thibodeau SN

更新日期：1999-07-13 00:00:00

abstract：OBJECTIVE:To examine nonmotor outcomes and correlates of quality of life (QoL) 3 and 12 months after unilateral focused ultrasound thalamotomy in tremor-dominant Parkinson disease (TDPD). METHODS:Twenty-seven patients with TDPD in a double-blind, sham-controlled, randomized clinical trial underwent comprehensive neuro...

journal_title：Neurology

authors： Sperling SA,Shah BB,Barrett MJ,Bond AE,Huss DS,Gonzalez Mejia JA,Elias WJ

更新日期：2018-10-02 00:00:00

abstract：BACKGROUND:In epilepsy as in other disorders, family history information is often obtained by asking patients about the medical histories of their relatives rather than interviewing or examining the relatives directly. The accuracy of this type of information for epilepsy and other seizure disorders is unclear. METHOD...

journal_title：Neurology

authors： Ottman R,Barker-Cummings C,Leibson CL,Vasoli VM,Hauser WA,Buchhalter JR

更新日期：2011-01-25 00:00:00

abstract：:Thirteen patients presented with brief, repetitive, stereotyped transient ischemic attacks, large artery atherostenoses or occlusions with impaired collateral flow to a cortical perfusion borderzone, and orthostatic hypotension (OH). OH was caused by diabetes mellitus, aging, and treatments for ischemic heart disease ...

journal_title：Neurology

authors： Dobkin BH

更新日期：1989-01-01 00:00:00

abstract：:We studied performance on tests of visual neglect and left lateral gaze after caloric stimulation in 18 patients with left-sided visual neglect after strokes. Except for one patient with absent vestibulo-ocular responses, all improved during caloric stimulation on the left by cold (LC) or on the right by warm water (R...

journal_title：Neurology

authors： Rubens AB

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:While stable xenon CT (Xe-CT) cerebral blood flow (CBF) is an accepted standard for quantitative assessment of cerebral hemodynamics, the accuracy of magnetic resonance perfusion-weighted imaging (PWI-MRI) is unclear. The Improved PWI Methodology in Acute Clinical Stroke Study compares PWI findings with Xe-C...

journal_title：Neurology

authors： Olivot JM,Mlynash M,Zaharchuk G,Straka M,Bammer R,Schwartz N,Lansberg MG,Moseley ME,Albers GW

更新日期：2009-03-31 00:00:00

abstract：:Loading doses of 15 to 20 mg per kilogram of both phenobarbital and phenytoin, administered intravenously, are necessary in the newborn to achieve rapid therapeutic plasma anticonvulsant levels. Maintenance doses of 3 to 4 mg per kilogram of both agents will maintain therapeutic levels. Phenytoin is, however, not pred...

journal_title：Neurology

authors： Painter MJ,Pippenger C,Wasterlain C,Barmada M,Pitlick W,Carter G,Abern S

更新日期：1981-09-01 00:00:00

abstract：:Acute chorea in a child followed ingestion of pemoline mesylate. In guinea pigs, in an experimental model of chorea, chronic administration of pemoline induced behavioral supersensitivity to other dopaminergic agonists. Pemoline is similar to both d-amphetamine and methylphenidate in altering central dopaminergic sens...

journal_title：Neurology

authors： Nausieda PA,Koller WC,Weiner WJ,Klawans HL

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:There is controversy over whether seizures, the most common manifestation of neonatal brain injury, may themselves damage the developing brain. OBJECTIVE:To determine if neonatal seizures are independently associated with brain injury in newborns with perinatal asphyxia. METHODS:Ninety term neonates were s...

journal_title：Neurology

authors： Miller SP,Weiss J,Barnwell A,Ferriero DM,Latal-Hajnal B,Ferrer-Rogers A,Newton N,Partridge JC,Glidden DV,Vigneron DB,Barkovich AJ

更新日期：2002-02-26 00:00:00

abstract：:The antimigraine efficacy of many drugs may be mediated less through their primary modes of action than through the common pathway of serotonergic transmission stabilization. Migraine treatment may be symptomatic, acute/abortive, or prophylactic. Because oral drug absorption is impaired during attacks, parenteral agen...

journal_title：Neurology

authors： Raskin NH

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The major histocompatibility complex (MHC) has been consistently associated with susceptibility to MS and the course of several other human autoimmune diseases. A putative association between the course and severity of MS and the MHC remains controversial. METHODS:DR and DQ genotyping by either restriction ...

journal_title：Neurology

authors： Weinshenker BG,Santrach P,Bissonet AS,McDonnell SK,Schaid D,Moore SB,Rodriguez M

更新日期：1998-09-01 00:00:00

abstract：:The authors describe two patients with clinical manifestations of the osmotic demyelination syndrome (ODS) and unusual MRI findings of gadolinium-enhancing peripheral cortical abnormalities. They propose that these represent extrapontine manifestations of ODS because neither patient had a notable hypoxic-ischemic insu...

journal_title：Neurology

authors： Calakos N,Fischbein N,Baringer JR,Jay C

更新日期：2000-10-10 00:00:00

abstract：OBJECTIVES:To determine the prognostic role of late auditory (N100) and cognitive evoked potentials (MMN) for awakening in a cohort of comatose patients categorized by etiology. METHODS:The authors prospectively studied a series of 346 comatose patients. Coma was caused by stroke (n = 125), trauma (n = 96), anoxia (n ...

journal_title：Neurology

authors： Fischer C,Luauté J,Adeleine P,Morlet D

更新日期：2004-08-24 00:00:00

abstract：:This is a report on hepatic adverse events associated with dantrolene therapy. All cases reported to the manufacturer are included, from all sources, through 1987. Of 122 cases containing sufficient data to analyze, 47 patients had asymptomatic transaminase elevations, 12 had additional mild (less than or equal to 2.5...

journal_title：Neurology

authors： Chan CH

更新日期：1990-09-01 00:00:00

abstract：:The authors report a double-blind, placebo-controlled, crossover study of talampanel in 49 patients with refractory partial seizures. Three doses of talampanel were investigated based on differences in patients' concomitant antiepileptic drug usage. Talampanel showed efficacy in reducing seizure frequency (p = 0.001) ...

journal_title：Neurology

authors： Chappell AS,Sander JW,Brodie MJ,Chadwick D,Lledo A,Zhang D,Bjerke J,Kiesler GM,Arroyo S

更新日期：2002-06-11 00:00:00

abstract：BACKGROUND:Both genetic and environmental factors play a role in the pathophysiology of MS and may influence the clinical expression of the disease. OBJECTIVE:To determine the contribution of familial factors to the clinical expression of MS. METHODS:The French Multiple Sclerosis Genetics Group identified 87 sibling ...

journal_title：Neurology

authors： Brassat D,Azais-Vuillemin C,Yaouanq J,Semana G,Reboul J,Cournu I,Mertens C,Edan G,Lyon-Caen O,Clanet M,Fontaine B

更新日期：1999-05-12 00:00:00

abstract：OBJECTIVE:The diagnosis of psychogenic nonepileptic seizures (PNES) can be challenging. In the absence of a gold standard to verify the reliability of the diagnosis by EEG-video, we sought to assess the interrater reliability of the diagnosis using EEG-video recordings. METHODS:Patient samples consisted of 22 unselect...

journal_title：Neurology

authors： Benbadis SR,LaFrance WC Jr,Papandonatos GD,Korabathina K,Lin K,Kraemer HC,NES Treatment Workshop.

更新日期：2009-09-15 00:00:00

abstract：OBJECTIVE:To perform an open-label, long-term efficacy and safety/tolerability study of vagus nerve stimulation (VNS) of 454 patients with refractory epilepsy. METHODS:Subjects were enrolled from five clinical trials of VNS between 1988 and 1995 after undergoing an implantation of a pulse generator in the chest and a ...

journal_title：Neurology

authors： Morris GL 3rd,Mueller WM

更新日期：1999-11-10 00:00:00