Abstract：
:The blood-nerve barrier (BNB) shields peripheral nerves from the blood in order to maintain the homeostasis of the nervous system. In the field of infectious diseases, little information is currently available concerning the BNB. Recently documented evidence in virology suggests that elevated permeability of the BNB by immune cells and the natural absence of the BNB in the olfactory mucosa play significant roles in neuroprotection as well as neuropathogenesis. Importantly, the BNB can behave more flexibly than previously thought. In the near future, drug delivery via manipulation of the BNB will shed light on new therapeutic and prophylactic strategies for serious and intractable nervous system infections.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Mori Idoi
10.4149/av_2018_103subject
Has Abstractpub_date
2018-01-01 00:00:00pages
28-32issue
1eissn
0001-723Xissn
1336-2305journal_volume
62pub_type
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