Abstract：
:Oral immunization of volunteers with a live tissue culture influenza A (H3N2) vaccine induced an increase in virus neutralizing (VN), haemagglutination inhibiting (HI) and neuraminidase inhibiting (NI) antibody. The dynamics of antibody and IgM and IgG immunoglobulin formation in the blood depended to a great extent on their prevaccination levels. The highest per cent of seroconversions was observed after the 3rd vaccination: a 4-fold or greater rise of VN antibody was found in 80% (titre increase by 3.0 log2 units), of HI antibody in 70% (titre increase by 2.6 log2 units) and NI antibody in 73% (titre increased by 2.5 log2 units) of the volunteers. The level of IgG increased after each vaccination but its highest level did not coincide in time with the maximum antibody production. High titres of the antibodies studied were recorded 1-2 months after the 3rd vaccination, irrespective of their prevaccination levels.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Alekseeva AK,Andzhaparidze OG,Gracheva EN,Sidorova LA,Melnikova SKsubject
Has Abstractpub_date
1979-01-01 00:00:00pages
59-66issue
1eissn
0001-723Xissn
1336-2305journal_volume
23pub_type
杂志文章相关文献
ACTA VIROLOGICA文献大全abstract：:The densities of purified herpes simplex virus (HSV) particles prepared from infected rabbit lung (ZP) and baby hamster kidney (BHK-21) cells were investigated in potassium tartrate (PT) and potassium citrate (PC) density gradients. Virions obtained from ZP cells exhibited a higher density than those from BHK-21 cells...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1976-12-01 00:00:00
abstract：:Human influenza virus A/Krasnodar/101/59 (H2N2) was passaged in chick fibroblast cultures in the presence of trypsin at suboptimal temperature. The virus which underwent 16 passages at 28 degrees C possessed cold-adapted (ca) and temperature sensitive (ts) phenotypes and formed larger plaques at the optimal temperatur...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：:Coxiella burnetii cells in both phase I and II reveal in sodium dodecylsulphate-polyacrylamide gel electrophoresis (SDS-PAGE) similar protein profiles with only small differences. C. burnetii protein profile in SDS-PAGE depended on the method of purification of C. burnetii cells from chick embryo yolk sacs. Immune mou...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：:The structure and cytopathology of obligate intracellular bacteria belonging to families Rickettsiaceae and Chlamydiaceae and their interaction with eukaryotic host cells were compared in electron microscopic studies. "Rickettsia-like" and "chlamydia-like" types of organization of bacterial cells and their interaction...
journal_title：Acta virologica
pub_type： 杂志文章,评审
doi：
更新日期：1984-03-01 00:00:00
abstract：UNLABELLED:Antigenic and genetic typing of pestiviruses isolated from Indian sheep and goats was carried out. Testing of 1777 sheep and 1026 goat blood samples collected between 2004 and 2008 resulted in isolation of twelve pestiviruses, seven from sheep and five from goats. All of them were antigenically typed as bovi...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2012_03_209
更新日期：2012-01-01 00:00:00
abstract：:no abstract Keywords: no keywords. ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2017_314
更新日期：2017-01-01 00:00:00
abstract：:According to the morphology, type and function of its structural components the segmented genome of type C influenza virus is similar to that of influenza viruses A and B. However, type C influenza virus differs from them by the reticular structure of virion surface, absence of the surface glycoprotein neuraminidase, ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1984-07-01 00:00:00
abstract：:Viraemia was studied in adult Clethrionomys glareolus subcutaneously infected with 12 strains of tick-borne encephalitis (TBE) virus isolated in western and eastern foci of TBE. Nine strains caused viraemia regularly or irregularly, reaching titres higher than the threshold level of TBE virus infectivity for its vecto...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:The coat protein (CP) gene of Prunus necrotic ringspot virus (PNRSV) was cloned into pET 16b vector and expressed in Escherichia coli. CP-enriched fractions were prepared from whole cell lysate by differential centrifugation. The fraction sedimenting at 20,000 x g for 30 mins was used for preparation of a rabbit antis...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2001-02-01 00:00:00
abstract：:Acute gastroenteritis (AGE) is one of the most frequently occuring illnesses in children and adults worldwide. In February 2017, two AGE outbreaks occurred in two adjacent schools in Huzhou city, Zhenjiang province of China. We detected high percentages of recombinant norovirus GII.P16/GII.2 in one school and chicken ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2019_312
更新日期：2019-01-01 00:00:00
abstract：:The cytotoxicity and antiviral activity of the caffeic acid oxidation product (KOP), a higher molecular polyphenolic compound of strong antiviral activity against herpesvirus hominis type 1 and type 2 (HVH 1, HVH 2), were tested in 6 cell cultures: rabbit kidney primary cells (RKP), rabbit testis primary cells (RTP), ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1983-05-01 00:00:00
abstract：:Sera of the influenza patients and healthy controls were tested for some types of autoantibody (SMA, ANA, ABBA, AMA). They were detected in 83.8% of the patients' sera and in 16.6% of controls. SMA were present in 77.4%, ANA in 54.8%, and ABBA in 16.1% of the patient's sera. AMA were not detected. A majority of the se...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1976-06-01 00:00:00
abstract：:Substance P, a neuropeptide of the tachykinin group, inhibits measles virus replication in cell culture and partially blocks viral fusion activity assayed in the haemolysis system. The ID50 for the inhibition of measles virus single-cycle replication is 0.6 mumol/l, and the effect is fully reversible. The antiviral ac...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：:Clover blotch virus (CBV) was purified by differential centrifugation or precipitation with polyethylene glycol 6000 or 20000. Analytical centrifugation of purified CBV preparations revealed 2 components, the proportions of the lighter (96 S) nad heavier (112 S) being 88 and 12%, respectively. RNA isolated from purifi...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1975-09-01 00:00:00
abstract：:The seed transmission of the Zucchini yellow mosaic virus (ZYMV) was studied in cucumber using two isolates unrelated in their biological characteristics. Although the virus could be readily detected in mature seeds harvested from infected cucumbers, the seedlings obtained from infected germinated seeds tested negativ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:A strain of rickettsiae, designated Crimea-108, was isolated from ticks Dermacentor marginatus in the Crimea in 1977. Its immunobiological characteristics involve low pathogenicity for experimental animals, moderate infectivity for chick embryos, and antigenic relatedness to spotted fever group (SFG) rickettsiae (R. s...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:A region of the UL24 gene of six Australian field isolates of Bovine herpesvirus 2 (BHV-2) was sequenced after a passage in Madin-Darby bovine kidney (MDBK) cells by polymerase chain reaction (PCR). While the PCR product covered the first half of the UL24 gene, a particular interest was focused on the 274-297 nucleoti...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:An evidence is accumulating that the oxygen tension exerts significant effect on the virus replication in vitro. When the in vitro oxygen tension is maintained at an in vivo physiological level, as a rule higher yields of human viruses are seen that at conventional culturing with access of an unphysiologically high ox...
journal_title：Acta virologica
pub_type： 杂志文章,评审
doi：
更新日期：1998-12-01 00:00:00
abstract：:This study reports on our experience with whole herpes simplex vaccines in Bulgaria for a period of 17 years. More than 1,500 immunized patients with herpes ophtalmicus showed a reduction of the recovery period, reduced number of the recurrences and reduced risk of visual damage. More than 14,000 patients suffering fr...
journal_title：Acta virologica
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:This study comprised 100 persons with antibodies to hepatitis C virus (HCV), including 77 intravenous drug users (IVDUs). They were tested with serological HCV typing assays (Murex HCV serotyping 1-6 assay; Chiron RIBA HCV Serotyping SIA). Patients with a positive polymerase chain reaction (PCR) for HCV (n = 66) were ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:To monitor genetic variation between Cucumber mosaic virus (CMV) isolates of northwest Iran, samples of cucurbitaceous plants expressing symptoms similar to those caused by CMV were collected. The samples were first screened by ELISA to detect CMV and to determine its subgroup. All detected CMV isolates appeared to be...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Cell-mediated reactions in measles cases, in direct contacts and healthy children were tested. Indices of phytohaemagglutinin-stimulated blastic transformation and leukocyte migration inhibition were evaluated. Positive reactions were found in the first and second weeks after manifestation of clinical symptoms. The ap...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：:The ability of human peripheral blood leukocytes to produce interferon in response to phage double-stranded (ds) RNA was studied. Under the conditions used, interferon was produced not only by lymphocytes but also by polymorphs and monocytes. These "pure" cultures showed no marked differences in the degree of interfer...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1977-11-01 00:00:00
abstract：:Phages are excellent models for studying the mechanism of DNA replication in prokaryotes. Identification of phage proteins involved in phage DNA replication is the first prerequisite for elucidation of the phage replication module. We focused on replication proteins gp41 (a putative helicase from SF2 superfamily), gp4...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2014_02_152
更新日期：2014-01-01 00:00:00
abstract：:Gamma irradiation is a non-thermal processing technique used to disinfect harmful microorganisms in agriculture. This technology has been shown to be an effective method to control bacterial and fungal plant pathogens. However, its effect on viral plant pathogen is less understood. Gamma irradiation was evaluated for ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2017_02_14
更新日期：2017-01-01 00:00:00
abstract：:The uses of the nonionic detergent Triton X-100 (TX-100) and the cationic cetyltrimethylammonium bromide (CTAB) for the production of tick-borne encephalitis (TBE) virus subunits were compared. TX-100 splitted the virus into haemagglutinating envelope components which contain the virion proteins V3 and V1 and into a l...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:The coat proteins of both ordinary (PVSO) and Andean (PVSA) strains were shown to be similar in molecular weights, peptide maps, amino acid analysis and reaction to a range of carlavirus antiseras. ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：:Results of the direct immunofluorescence (IF) test in 152 clinical specimens (throat swabs) were compared with those of respiratory syncytial virus (RSV) isolation. The prevalence of RSV infections in the upper and lower respiratory tract was high especially in infants until 12 months of age. The average RSV isolation...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1987-09-01 00:00:00
abstract：:An assay protocol based on exploiting the polymerase chain reaction (PCR) for the direct detection of influenza B virus in throat swabs is described. By the use of PCR with nested primers, it was possible to detect the virus in throat swabs. Dilution experiments showed that as little as 1 plaque forming unit of virus ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:Human choriocarcinoma cells of the JAR line, with no demonstrable surface CD4 receptor were infected with human immunodeficiency virus type 1 (HIV-1), strain RF. Primer-directed enzymatic DNA amplification (polymerase chain reaction, PCR) detected the presence of viral DNA when the cultures were investigated at day 5 ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
