Abstract：
:An abortive infection was induced in L cells by influenza virus A/Hong Kong/68 (H3N2). With the use of antibody and peroxidase-labelled protein A, the localization of virus protein synthesis but not the maturation of virus particles was demonstrated at the ultrastructural level. Five days after inoculation (p.i.), the synthesis of viral haemagglutinin was localized in the region of the rough endoplasmic reticulum; at late intervals p.i., haemagglutinin accumulated in the plasma membranes, where membrane vesicles, containing haemagglutinin in their membranes, were released from the cell surface. The cytoplasmic viral ribonucleoprotein was localized in the region of free cytoplasmic ribosomes and that of the outer sheet of the nuclear membrane. Viral proteins were detected in the cytoplasm and plasma membranes also after 70 and 390 days of passaging of the cells or of their long-term cultivation with regular change of medium.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Ciampor F,Sidorenko EV,Taikova NV,Bystrická Msubject
Has Abstractpub_date
1981-11-01 00:00:00pages
381-9issue
6eissn
0001-723Xissn
1336-2305journal_volume
25pub_type
杂志文章相关文献
ACTA VIROLOGICA文献大全abstract：:The plaque size and distribution of prototype La Crosse (LAC) and Jamestown Canyon (JC) viruses were investigated in Vero cell cultures. The effect of serial passage of the viruses in their natural vertebrate hosts - the chipmunk and grey squirrel for LAC and the white-tailed deer for JC virus - was studied. Prototype...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1975-07-01 00:00:00
abstract：:Homology between DNAs of some orthopoxviruses: vaccinia, neurovaccinia, cowpox, ectromelia, variola and white-pox was studied. By the method of molecular hybridization of labelled virion DNAs of the viruses studied with an excess of unlabelled vaccinia DNA and further treatment of the hybridized products by the single...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：:RNA interference (RNAi) is a biological phenomenon in which introduction of a small, double-stranded interfering RNAs (siRNAs) into a cell causes a specific degradation of homologous single-stranded RNA. siRNA can be delivered into the cell by different approaches including synthetic RNA, in vitro transcribed RNA and ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Structural proteins V1, V2 and V3 of Japanese encephalitis virus (JEV) were isolated and purified by means of polyacrylamide gel electrophoresis (PAGE) in the presence of sodium dodecyl sulfate (SDS) and extracted from the sliced gel. The purified and renatured V3 envelope protein was found to bind to receptors for JE...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1982-09-01 00:00:00
abstract：:Papaya leaf distortion mosaic virus is highly destructive to commercial papaya production. Here, the complete genome sequence was determined for an isolate of papaya leaf distortion mosaic virus, designated PLDMV-DF, infecting the commercialized papaya ringspot virus (PRSV)-resistant transgenic papaya from China. Excl...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2013_04_452
更新日期：2013-01-01 00:00:00
abstract：:The effects of edeine, hygromycin B and alpha-sarcin on the synthesis of virus-specific proteins and formation of infectious virions was studied in cells infected with fowl plague virus (FPV). The manifestation of the antiviral effect of edeine depended on the peculiarities of the FPV strains and the host-cell systems...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1981-05-01 00:00:00
abstract：:Purified lipopolysaccharide-protein complex (LPS-PC) extracted by trichloroacetic acid from phase I Coxiella burnetii organisms induced in mice and rabbits fair levels of antibodies directed to antigen 1 and antigen 2, as detected by complement-fixation (CF), microagglutination (MA), opsonization-phagocytosis (OP) and...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：:Hypothiocyanite (OSCN-) is a natural component of human saliva and is produced by the lactoperoxidase (LPO)/thiocyanate/hydrogen peroxide (H2O2) system. OSCN- has been previously shown to exhibit antiviral activity against influenza viruses (IFV) A/H1N1/2009 and A/H1N2/2009 in vitro as well as antimicrobial and antifu...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2018_408
更新日期：2018-01-01 00:00:00
abstract：:An atypical mild isolate HV5 of Grapevine fanleaf virus (GFLV) was found in a South Moravian viticulture region in Czech Republic. Partial sequence of its RNA2 was determined and compared with available sequences of typical GFLV isolates. Two genomic regions, namely a 814 nt-long one spanning the movement protein (MP)...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Human papillomavirus (HPV) E6 and E7 gene products play a central role in the induction of benign proliferation and malignant transformation by interacting with several cellular regulatory proteins such as p53, p16(INK4a), and nuclear factor kappaB (NF-kappaB). In this study, HPV DNA was detected by in situ hybridizat...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2009_01_43
更新日期：2009-01-01 00:00:00
abstract：:In order to investigate the growth of hepatitis A virus (HAV) in murine cells, L929 cells of the established mouse cell line were transfected with the virion RNA or infected with the virions and examined for the formation of negative-strand RNA and the rise of the viral infectivity titer. In both the transfected and i...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Peanut stripe virus (PStV) is one of the most common viruses infecting peanut that causes great economic losses every year. The 3ʹ-terminal 1082 bp of 74 PStV isolates collected from 12 districts of Shandong province, China were sequenced. Their coat protein (CP) genes were 864 bp in length and shared identities of 98...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2011_02_123
更新日期：2011-01-01 00:00:00
abstract：:We isolated plaque-size variants of a South American strain of yellow fever virus, and compared their ability to infect orally and be transmitted by vector Aedes aegypti mosquitoes with that of the uncloned, parental virus. We analyzed the same clonal isolates in mouse virulence experiments. No significant differences...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1988-05-01 00:00:00
abstract：:Herpes zoster (HZ) is a neurocutaneous disease caused by Varicella-zoster virus (VZV) as a consequence of declined cell-mediated immunity, immune suppression and immunodeficiency. As reactivation of JC polyomavirus (JCPyV) might be linked with immunodeficiency or immunosuppressive therapy, the relationship between HZ ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:A strain designated 42-Edmonston was isolated from the brain of a Syrian hamster 30 days after inoculation during the neonatal period with the reference "wild" measles virus strain Edmonston which produced a latent infection accompanied by production of measles antibody and insignificant pathomorphological changes. In...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1977-05-01 00:00:00
abstract：:Cauliflower mosaic virus (CaMV) - a plant pararetrovirus that naturally causes diseases in Brassicaceae and Solanaceae plant hosts worldwide - has been detected by PCR for the first time in herbarium samples of Usnea sp. lichens. The virus's presence in these lichens did not result in any micro- or macromorphological ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2016_02_196
更新日期：2016-06-01 00:00:00
abstract：:Chromosomal DNAs isolated from eight individuals from the Slovak population and from lymphoblastoid Namalwa cells were analyzed for the presence of genes coding for three subvariants of human interferon-alpha 2 (IFN-alpha 2), namely a, b, and c. The respective genes are regarded allelic, because they differ in the cod...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:Neopterin and soluble CD14 (sCD14) are detected at high levels in hepatitis C virus (HCV) infections. We aimed to evaluate the role of these plasma immune activation biomarkers, for the indirect assessment of immune activation status of patients with low anti-HCV reactivity and a HCV infection. Low anti-HCV reactivity...
journal_title：Acta virologica
pub_type： 杂志文章,多中心研究
doi：10.4149/av_2017_304
更新日期：2017-01-01 00:00:00
abstract：:The structure and cytopathology of obligate intracellular bacteria belonging to families Rickettsiaceae and Chlamydiaceae and their interaction with eukaryotic host cells were compared in electron microscopic studies. "Rickettsia-like" and "chlamydia-like" types of organization of bacterial cells and their interaction...
journal_title：Acta virologica
pub_type： 杂志文章,评审
doi：
更新日期：1984-03-01 00:00:00
abstract：:no abstract Keywords: no keywords. ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2017_314
更新日期：2017-01-01 00:00:00
abstract：:A peculiar grouping of Creutzfeldt-Jacob disease (CJD) and of other organic presenile dementia (OPD) cases in a small, prevalently rural area in Czechoslovakia to the east of 19 degrees 35' E and to the north of 48 degrees 15' N was studied. Between August, 1972 and November, 1976, three histologically proven CJD case...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：:An analysis of the methods of testing the antiviral activity in vitro (in cell cultures) and in vivo (in experimental virus infections) is presented. The necessity of applying two-stage screening in vitro is emphasized. The chemotherapeutic viral models is in vitro testing as well as the principles of modelling of exp...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：:Cytological and cytochemical studies on Swiss and random-bred white mice susceptible to Rickettsia tsutsugamushi infection as well as resistant C57 Black 6 and CBA mice revealed a clear-cut relationship between the severity of infection and the pattern of macrophage reaction. In highly susceptible mice the fatal infec...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1976-04-01 00:00:00
abstract：:Six monoclonal antibodies (MoAbs) directed against glycoproteins of bovine leukaemia virus (BLV) were prepared and characterized. Comparison of these MoAbs with anti-gp51 MoAbs of known epitope specificity by competition antibody binding assay allowed to distinguish two new conformational epitopes C1 and C2 on the mol...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：:In the summer 1999, a measles outbreak occurred in Uruguai. During this outbreak 58 cases were recorded, 36 of which were laboratory confirmed as positive for measles virus (MV) IgM. The cases occurred in touristic places (Montevideo and Maldonado) predominantly among health facilities and tourist service personnel. U...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2000-02-01 00:00:00
abstract：:The efficacy of hepatitis B virus (HBV) vaccine alone (group I) or in combination with hepatitis B immunoglobulin (HBIG) (group II) for prevention of perinatal transmission of the virus was assessed in 21 and 24 neonates, respectively. 58 infants who could not be vaccinated constituted the control group. It was observ...
journal_title：Acta virologica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1992-08-01 00:00:00
abstract：:Immobilization stress (hypokinesis) in Balb/c mice may aggravate asymptomatic infection with Langat virus (strain TP-21) as evidenced by 4-fold increased lethality in comparison with control animals. The virus levels in the spleen and brain of stressed and infected mice and the in vitro yield of the virus in immunocom...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：:Alzheimer's disease (AD) the most common form of dementia is characterized by cognitive decline and progressive loss of neurons in the central nervous system. Despite huge scientific progress, there are only few animal models that recapitulate at least majority of the AD pathology and related symptomatology. Therefore...
journal_title：Acta virologica
pub_type： 杂志文章,评审
doi：10.4149/av_2017_01_13
更新日期：2017-01-01 00:00:00
abstract：:Avian infectious bronchitis virus (IBV) and avian pathogenic Escherichia coli (APEC) are two important respiratory pathogens in the chicken. The co-infection can lead to chronic complications and considerable economic losses in the poultry industry worldwide. In the present study, we compared differential transcriptio...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2020_413
更新日期：2020-01-01 00:00:00
abstract：:Although most pathogenic rickettsiae are obligate intracellular parasites, it is clear that they are bacteria. As such, form and function in rickettsiae are closely similar to form and function found in their free-living counterparts. This review of rickettsiae as bacteria portrays the broad similarities of rickettsia...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1985-09-01 00:00:00
