Abstract：
:Differences in interfering activities were demonstrated between low-passage epidemic and thermosensitive cold-adapted strains of influenza viruses A and B in experiments on chick embryos inoculated on the chorioallantoic membranes and on white mice. At a high multiplicity of infection the thermosensitive variants showed a higher interfering activity as compared with the original viruses which had undergone a limited number of chick embryo passages.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Aleksandrova GI,Dekhtyareva NI,Medvedeva TE,Shneider MAsubject
Has Abstractpub_date
1982-05-01 00:00:00pages
113-8issue
3eissn
0001-723Xissn
1336-2305journal_volume
26pub_type
杂志文章相关文献
ACTA VIROLOGICA文献大全abstract：:Chronic infection of HeLa cells was induced by an attenuated variant of Japanese encephalitis (JE) virus (HeLa-K3 cell line). The chronic infection was characterized by alternating phases of degeneration and recovery of the cell monolayer. JE virus was regularly released into the medium of chronically infected cell cu...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1980-12-01 00:00:00
abstract：:14C-labelled Lassa virus was purified by isopycnic centrifugation and split to subvirion fractions. The purified virus was treated with nonionic detergents Nonidet P-40 (NP-40) and with octylglycoside. After ultracentrifugation in urographin density gradient, two subvirion fractions with buoyant density of 1.24-1.26 a...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Histological changes were studied in the central nervous system (CNS) of 58 Macaca rhesus monkeys, infected intracerebrally (i.c.) and subcutaneously (s.c.) with tick-borne encephalitis (TBE) virus. Subacute degenerative process in the CNS occurred in 7 monkeys on days 15-24 post-infection (p.i.), while chronic degene...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1984-05-01 00:00:00
abstract：:An Indian isolate of Goatpox virus (GTPV) was adapted and propagated in Vero cells for development of an attenuated virus. The virus was initially passaged in primary lamb testes cells and subsequently in Vero cells. At the 55th passage, the virus showed evidence of attenuation when tested for safety in seronegative g...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The human immunodeficiency virus (HIV) envelope, via a key extracellular amino acid sequence, may simulate the functionality of native undecapeptide substance P (SP) acting through the host's neurokinin 1 (SP preferring) receptor (NK-1R). Human monocytes and macrophages express both NK-1Rs and SP. In HIV/AIDS the NK-1...
journal_title：Acta virologica
pub_type： 杂志文章,评审
doi：10.4149/av_2019_302
更新日期：2019-01-01 00:00:00
abstract：:Two Infectious bursal disease virus (IBDV) isolates, NP1SSH and NP2K were obtained from a severe infectious bursal disease (IBD) outbreak in Nepal in 2002. The hypervariable (HV) region of VP2 gene (1326 bp) of the isolates was generated by RT-PCR and sequenced. The obtained nucleotide sequences were compared with tho...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Experimental parenteral inoculation of Dermacentor reticulatus ticks with the rickettsia Coxiella burnetii (C.b.) and tick-borne encephalitis (TBE) virus resulted in a generalized rickettsial and viral infection, irrespective of whether the agents were given simultaneously or by a 7 days interval apart. Both agents mu...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Human influenza virus A/Krasnodar/101/59 (H2N2) was passaged in chick fibroblast cultures in the presence of trypsin at suboptimal temperature. The virus which underwent 16 passages at 28 degrees C possessed cold-adapted (ca) and temperature sensitive (ts) phenotypes and formed larger plaques at the optimal temperatur...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：:While the main interest in the pathogenesis of herpes simplex virus (HSV) in the sixties had been focussed on acute infections, in the seventies latent infection has become the main foal of investigation. Despite of overwhelming literature, the HSV persistence has remained a continuing problem from the practical as we...
journal_title：Acta virologica
pub_type： 杂志文章,评审
doi：
更新日期：1983-09-01 00:00:00
abstract：:The immune response of mice injected with influenza vaccine (FluV) or pneumococcal vaccine (PV) given separately or simultaneously was evaluated. Balb/c mice were divided into six groups. Group I served as control, the mice in group II were injected intraperitoneally with PV, in group III intramuscularly with FluV two...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Palma and Bhanja bunyaviruses replicated in Dermacentor marginatus, D. reticulatus, Rhipicephalus sanguineus, R. appendiculatus and Ixodes ricinus ticks after parenteral inoculation and appropriate incubation and feeding. Palma virus was transmitted to D. marginatus and D. reticulatus males, D. reticulatus and R. sang...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:Some differences were established between mopyridone-sensitive (MCU-s) wild strain and mopyridone-resistant (MCU-r) mutant progenies of influenza virus A/Hong Kong/1/68 (H3N2). The virions of MCU-r mutant had a lower buoyant density in linear sucrose gradient as compared to those of MCU-s strain, and an increased abil...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:A lipophilic thermostable lipopolysaccharide (LPS) complex was isolated by phenol extraction from purified suspensions of the typhus group rickettsiae. The LPS complex is antigenic and possesses some endotoxic properties such as toxicity for actinomycin D-treated mice, pyrogenicity for rabbits and guinea pigs, ability...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1977-09-01 00:00:00
abstract：:Herpes simplex virus (HSV) DNA was found by spot blot hybridization in the right nc. amygdalae of 3 out 10 patients who underwent curative stereotactic surgery for severe mental retardation with aggressive behavior and/or paranoic schizophrenia. Of these, 6 were also tested for the presence of CMV DNA sequences with n...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：:The coat proteins of both ordinary (PVSO) and Andean (PVSA) strains were shown to be similar in molecular weights, peptide maps, amino acid analysis and reaction to a range of carlavirus antiseras. ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：:The techniques of reverse transcription-polymerase chain reaction (RT-PCR) and restriction analysis were used to differentiate highly virulent Indian field isolates of infectious bursal disease virus (IBDV) from vaccine strains. Primers were designed to amplify the variable region of VP2 gene coding for major virus ne...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：:Two monoclonal antibodies (MoAb) to the Skalica virus from the tick-borne encephalitis (TBE) complex were used to compare Karshi and Royal Farm viruses with the Russian spring-summer encephalitis, Central European encephalitis (Hypr and Kumlinge strains) Skalica, Langat and Powassan viruses. The first MoAb was prepare...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：:Histology of skin lesions and demonstration in them of Rickettsia conorii by direct immunofluorescence test (DIF) are presented in 13 patients with Mediterranean spotted fever (MSF). The lymphohistiocytic vasculitis which dominated the picture is not specific, however, it could be suggestive for the diagnosis of ricke...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：:Recently, mitochondria have been shown to have a vital role in the innate immune response to viral infection. In response, viruses such as adenovirus, have developed mechanisms to alter mitochondrial function through direct or indirect interaction with the mitochondria. The interaction of human recombinant adenoviral ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2019_114
更新日期：2019-01-01 00:00:00
abstract：:The influence of the isolation procedure of Sendai virus glycoproteins from the virus surface on their neuraminidase and haemagglutinating activities, as well as on some structural properties was studied. These glycoproteins exhibited lower specific neuraminidase and haemagglutinating activities than those of intact v...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1978-11-01 00:00:00
abstract：:RNA interference (RNAi) is a biological phenomenon in which introduction of a small, double-stranded interfering RNAs (siRNAs) into a cell causes a specific degradation of homologous single-stranded RNA. siRNA can be delivered into the cell by different approaches including synthetic RNA, in vitro transcribed RNA and ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Human papillomavirus (HPV) E6 and E7 gene products play a central role in the induction of benign proliferation and malignant transformation by interacting with several cellular regulatory proteins such as p53, p16(INK4a), and nuclear factor kappaB (NF-kappaB). In this study, HPV DNA was detected by in situ hybridizat...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2009_01_43
更新日期：2009-01-01 00:00:00
abstract：:A comparative polarographic study on the alkaline degradation of tobacco mosaic virus (TMV) strain vulgare and its mutant TMV 483, having histidine instead of glutamine at position 9 in the polypeptide chain, was performed. In the course of alkaline degradation and subsequent incubation in the supporting electrolyte a...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1977-09-01 00:00:00
abstract：:A resistant influenza virus has been obtained during successive passages of influenza A virus in 10 to 11-day-old chick embryos (CE) in the presence of 2-(1'-amino-ethyl)-bicyclo(2.2.1) heptane chlorohydrate possessing a high antiviral activity. The virus resistance to the inhibitor was not lost after one passage in t...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:An abortive infection was induced in L cells by influenza virus A/Hong Kong/68 (H3N2). With the use of antibody and peroxidase-labelled protein A, the localization of virus protein synthesis but not the maturation of virus particles was demonstrated at the ultrastructural level. Five days after inoculation (p.i.), the...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1981-11-01 00:00:00
abstract：:In the blood of patients with rheumatoid arthritis and/or sclerodermia systematica usually acid-labile interferon-alpha (IFN-alpha) was found. Blood leukocytes cannot be considered the source of its production as they spontaneously produce IFN-gamma identified with specific antiserum. Blood leukocytes of tested patien...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:Sensitivity and specificity of a modified agar gel immuno-diffusion (AGID) test for the diagnosis of enzootic bovine leukosis was compared in 609 sera using the standard method, the modified test, and ELISA. The modifications concerned the composition of agar gel (1.8% Bacto-agar Difco), addition of polyethylene glyco...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Thirty four chemical compounds were injected into rabies infected mice by intramuscular (i.m.) route. Twenty four compounds such as well known therapeutic agents: amantadine, lipacids, phenol compounds, didemnin-B, procaine, nucleosides analogues (ribavirin, tiazofurin, pyrazofurin) had no effect. Two compounds had a ...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Hepatitis C virus (HCV) infection represents a serious public health problem worldwide. Development of new therapeutics against HCV has been hampered by the lack of a small-animal model. Until now, it has been unclear which host factors influence the HCV infection. It was known that human CD81 (hCD81) or low-density l...
journal_title：Acta virologica
pub_type： 杂志文章
doi：10.4149/av_2009_03_185
更新日期：2009-01-01 00:00:00
abstract：:A strain designated 42-Edmonston was isolated from the brain of a Syrian hamster 30 days after inoculation during the neonatal period with the reference "wild" measles virus strain Edmonston which produced a latent infection accompanied by production of measles antibody and insignificant pathomorphological changes. In...
journal_title：Acta virologica
pub_type： 杂志文章
doi：
更新日期：1977-05-01 00:00:00
