Immune response to influenza and pneumococcal vaccines in mice.

Abstract:

:The immune response of mice injected with influenza vaccine (FluV) or pneumococcal vaccine (PV) given separately or simultaneously was evaluated. Balb/c mice were divided into six groups. Group I served as control, the mice in group II were injected intraperitoneally with PV, in group III intramuscularly with FluV two weeks after the onset of the study. The mice from group IV received PV and 2 weeks later were injected with FluV, mice in group V were given FluV, whereas group VI received both FluV and PV simultaneously. The results showed that the proliferative response of peripheral blood mononuclear cells (PBMC) significantly increased in animals from groups II, V and VI, whereas the proliferation of splenocytes increased in mice from groups II, III, IV, and VI. These observations indicate a comparable effect of both vaccines, at least when the proliferative response of PBMC and splenocytes were considered.

journal_name

Acta Virol

journal_title

Acta virologica

authors

Bessler H,Blay A,Djaldetti M

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

125-9

issue

2

eissn

0001-723X

issn

1336-2305

journal_volume

52

pub_type

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