Abstract:
:The immune response of mice injected with influenza vaccine (FluV) or pneumococcal vaccine (PV) given separately or simultaneously was evaluated. Balb/c mice were divided into six groups. Group I served as control, the mice in group II were injected intraperitoneally with PV, in group III intramuscularly with FluV two weeks after the onset of the study. The mice from group IV received PV and 2 weeks later were injected with FluV, mice in group V were given FluV, whereas group VI received both FluV and PV simultaneously. The results showed that the proliferative response of peripheral blood mononuclear cells (PBMC) significantly increased in animals from groups II, V and VI, whereas the proliferation of splenocytes increased in mice from groups II, III, IV, and VI. These observations indicate a comparable effect of both vaccines, at least when the proliferative response of PBMC and splenocytes were considered.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Bessler H,Blay A,Djaldetti Msubject
Has Abstractpub_date
2008-01-01 00:00:00pages
125-9issue
2eissn
0001-723Xissn
1336-2305journal_volume
52pub_type
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