Histopathology and immunopathology of skin biopsy specimens in Mediterranean spotted fever.

Abstract:

:Histology of skin lesions and demonstration in them of Rickettsia conorii by direct immunofluorescence test (DIF) are presented in 13 patients with Mediterranean spotted fever (MSF). The lymphohistiocytic vasculitis which dominated the picture is not specific, however, it could be suggestive for the diagnosis of rickettsiosis. By DIF we demonstrated rickettsial coccobacillary forms in all the patients: in 12 macular lesions and in one "tache noire". The diagnosis was also confirmed by indirect immunofluorescence test in each case. DIF test was shown to be sensitive, specific and reliable in early diagnosis of MSF.

journal_name

Acta Virol

journal_title

Acta virologica

authors

Dujella J,Morović M,Dzelalija B,Gverić M,Novaković S

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

566-72

issue

6

eissn

0001-723X

issn

1336-2305

journal_volume

35

pub_type

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