Persistence of Rickettsia prowazekii with different initial biological properties in infected cotton rats.

Abstract:

:Evidence has been obtained indicating the association of certain biological properties of Rickettsia prowazekii with their capacity for persistence. Highly virulent rickettsial cultures inducing increased levels of complement-fixing antibodies were shown to cause a high percentage of rickettsial carriers in infected cotton rats. Within an interval of 133-189 days after inoculation with the virulent Breinl strain, rickettsial carrier-state was still demonstrable in 20% of the animals. The vaccine strain E of R. prowazekii had a low capacity for persistence in cotton rats, because 64 days after inoculation all animals were found free of rickettsiae.

journal_name

Acta Virol

journal_title

Acta virologica

authors

Ignatovich VF,Barkhatova OI,Rydkina EB

subject

Has Abstract

pub_date

1983-11-01 00:00:00

pages

528-32

issue

6

eissn

0001-723X

issn

1336-2305

journal_volume

27

pub_type

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