Abstract:
:Homology between DNAs of some orthopoxviruses: vaccinia, neurovaccinia, cowpox, ectromelia, variola and white-pox was studied. By the method of molecular hybridization of labelled virion DNAs of the viruses studied with an excess of unlabelled vaccinia DNA and further treatment of the hybridized products by the single-stranded-specific nuclease S1, it was shown that the concentration of unlabelled vaccinia virus DNA, converting 50% of homologous labelled DNA into a hybrid, converted under similar experimental conditions into a hybrid 50% of labelled neurovaccinia virus DNA, 48% of white-pox virus DNA, 43% of variola virus DNA, about 30% of cowpox virus DNA and 27% of ectromelia virus DNA. Based on the quantitative data obtained the relationship between viruses of this subgroup and the possible origin of vaccinia virus is discussed.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Chernos VI,Surgai VVsubject
Has Abstractpub_date
1980-03-01 00:00:00pages
81-8issue
2eissn
0001-723Xissn
1336-2305journal_volume
24pub_type
杂志文章相关文献
ACTA VIROLOGICA文献大全abstract::The achievements and perspectives of genetic manipulations are described aiming at preparation of first generation subunit vaccines based on the synthesis in bacterial and eukaryotic cells of full-sized virion proteins expressing the main antigenic determinants. The preparation of such vaccines in bacterial cells seem...
journal_title:Acta virologica
pub_type: 杂志文章,评审
doi:
更新日期:1985-05-01 00:00:00
abstract::The effects of edeine, hygromycin B and alpha-sarcin on the synthesis of virus-specific proteins and formation of infectious virions was studied in cells infected with fowl plague virus (FPV). The manifestation of the antiviral effect of edeine depended on the peculiarities of the FPV strains and the host-cell systems...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00
abstract::Nucleoprotein (NP) complexes constituting the material of the postmicrosomal sediment (POMS) and its three basic components (A, B, C) (Ríman and Sulová, 1997a), harboring an extrachromosomal DNA closely related to AMV DNA were found to possess DNA- and RNA-synthesizing activities (SAs) reflecting the ability of this m...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1997-08-01 00:00:00
abstract::The human immunodeficiency virus (HIV) envelope, via a key extracellular amino acid sequence, may simulate the functionality of native undecapeptide substance P (SP) acting through the host's neurokinin 1 (SP preferring) receptor (NK-1R). Human monocytes and macrophages express both NK-1Rs and SP. In HIV/AIDS the NK-1...
journal_title:Acta virologica
pub_type: 杂志文章,评审
doi:10.4149/av_2019_302
更新日期:2019-01-01 00:00:00
abstract::Homologous interference in vitro is defined as the ability of primary viral infection to prevent secondary homologous superinfection. Non-cytopathic bovine viral diarrhea virus (ncp BVDV) has been classified according to the exaltation of Newcastle disease phenomenon (END) as END positive (E+) and END negative (E-) st...
journal_title:Acta virologica
pub_type: 杂志文章
doi:10.4149/av_2018_228
更新日期:2018-01-01 00:00:00
abstract::The first confirmed evidence of scrapie in Slovakia was demonstrated in one sheep of the autochthonous Merino breed from the southeastern part of the country. The reported scrapie was diagnosed during compulsory transmissible spongiform encephalitis (TSE) screening of sheep over 9 months of age assigned for consumptio...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::Homologs of Bombyx mori nuclear polyhedrosis virus (BmNPV) Bm67 gene ORF67 have been found in the genome of all lepidopteran nuclear polyhedrosis viruses, but their function is still not very clear. In order to analyze it we employed a bacmid harboring the complete BmNPV genome including the Bm67 gene and expressing ...
journal_title:Acta virologica
pub_type: 杂志文章
doi:10.4149/av_2015_01_40
更新日期:2015-03-01 00:00:00
abstract::A lipophilic thermostable lipopolysaccharide (LPS) complex was isolated by phenol extraction from purified suspensions of the typhus group rickettsiae. The LPS complex is antigenic and possesses some endotoxic properties such as toxicity for actinomycin D-treated mice, pyrogenicity for rabbits and guinea pigs, ability...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1977-09-01 00:00:00
abstract::An improved method of isolation of Coxiella burnetti proteins was developed. It consists of a combination of detergent (sodium dodecyl sulphate (SDS) or sodium deoxycholate (DOC) and hot phenol treatments. The resulting phenol phase (PP) contained either lipopolysaccharide-(LPS) free proteins (DOC extraction) or prote...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract::Mouse sera collected from day 4 to day 133 postinfection (p.i.) with phase I Coxiella burnetii strain Nine Mile were analysed by immunoblotting with phase I C. burnetii cell lysate. Antibodies of IgG class protein antigens were revealed already on day 10 p.i. (60, 49 and 27 kD proteins), followed by those to 77 kD pro...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::A limited epidemic, with important mortality among the initial human cases, occured in a forest region in the north of Gabon by the end of 1994. It was identified as yellow fever according to first serological and reverse transcription/polymerase chain reaction (RT-PCR) results, but no virus was isolated. We received ...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract::Different concentrations of chemically-treated (by potassium periodate oxidation or mild acid hydrolysis) purified phase I Coxiella burnetii (C.b.) corpuscles and natural (untreated) purified phase I and phase II C.b. corpuscles were compared by ELISA for detection of both phase I (directed to antigen 1) and phase II ...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::In the last two decades, preparation of infectious RNA or DNA clones of plant viruses has transformed to a standard laboratory technique, providing an excellent tool for the research of viral gene functions and virus-host interactions. A full-length clone can be transformed in vitro to a viral vector expressing foreig...
journal_title:Acta virologica
pub_type: 杂志文章,评审
doi:
更新日期:2007-01-01 00:00:00
abstract::A decrease in creatine phosphokinase (CPK) activity was observed in plasma membranes (PM) treated with native A/WSN influenza virus but not in PM treated with heat-inactivated virus. The decrease in CPK activity depended on the amount of virus added to PM, on the pH of the medium and on the quality of the isolated PM....
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract::Studies on interaction between Herpes simplex virus 1 (HSV-1) and human fibroblasts KMB-17 have demonstrated that HSV-1 binding to the cell surface could induce a specific gene response. In this study, the HSV-1 stimulation-related gene 1 (HSRG1), a new so far unknown gene function of cellular response induced by a sp...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:UNLABELLED:Influenza A (H1N1) virus is an important pathogen that can be transmitted in the enzootic cycle involved in influenza epidemics. In this study, we analyzed natural selection on the 260 sequences of subtype 1 hemagglutinin (HA1) gene of H1N1 viruses isolated from humans and swine in Asia. Nonsynonymous and sy...
journal_title:Acta virologica
pub_type: 杂志文章
doi:10.4149/av_2010_02_113
更新日期:2010-01-01 00:00:00
abstract::Viraemia was studied in adult Clethrionomys glareolus subcutaneously infected with 12 strains of tick-borne encephalitis (TBE) virus isolated in western and eastern foci of TBE. Nine strains caused viraemia regularly or irregularly, reaching titres higher than the threshold level of TBE virus infectivity for its vecto...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1979-05-01 00:00:00
abstract::Most adults are asymptomatically infected with Epstein-Barr virus (EBV). Primary EBV infection is commonly associated with acute infectious mononucleosis (IM). T cell immune activation plays an important role in EBV-associated diseases. IM shows a mainly Th1-type profile, so Th1-type cytokines such as interleukin-2 (I...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Influenza B viruses isolated in 1940, 1950 and 1970 belonged to antigenically remote subgroups according to the antigenic composition of haemagglutinin (HA). Antigenically related strains isolated in 1972-1976 differed by their reproduction capability, by their sensitivity to inhibitors in mammalian sera and by affini...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1983-09-01 00:00:00
abstract::Restriction endonuclease fragment length polymorphism (RFLP) analysis and polymerase chain reaction (PCR) were used to characterize the genotypic diversity of 7 strains of Rickettsia conorii from South Africa, Ethiopia, Morocco, India and Russia. The strains of R. conorii were divided into four genotypes by Rsa I or P...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1994-02-01 00:00:00
abstract::The identification and genetic characterization of bovine viral diarrhea virus (BVDV) isolate 17237 detected in western Slovakia is described. The analysis of 5'-untranslated region (5'-UTR), autoprotease (Npro) gene, and structural genes (C, Erns, E1, E2) was carried out. The percentage of nucleotide and deduced amin...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::The results of the study on the combined antiviral activity of the SHS-174 preparation (a lyophylized infusion from three higher plants) and three amantadine derivatives (rimantadine, amantadine glucuronide and its derivative) are presented. The antiviral effect of the drugs on the reproduction of influenza virus stra...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1993-08-01 00:00:00
abstract::Hypothiocyanite (OSCN-) is a natural component of human saliva and is produced by the lactoperoxidase (LPO)/thiocyanate/hydrogen peroxide (H2O2) system. OSCN- has been previously shown to exhibit antiviral activity against influenza viruses (IFV) A/H1N1/2009 and A/H1N2/2009 in vitro as well as antimicrobial and antifu...
journal_title:Acta virologica
pub_type: 杂志文章
doi:10.4149/av_2018_408
更新日期:2018-01-01 00:00:00
abstract::Interferon (IFN) was induced in chicken peripheral blood leukocytes by exposure to Concanavalin A (Con A). It has reached a maximum level 96 hr after stimulation with the optimum dose of 10 micrograms/ml. The IFN was partially purified by chromatography on controlled-pore glass adsorbent and was characterized as a fai...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1986-03-01 00:00:00
abstract::Chromic chloride and tannic acid methods were elaborated to bind purified adenovirus hexons to sheep red blood cells (SRBC). Either method gave very sensitive haemagglutination (HA) with adenovirus antisera, but treatment with tannic acid was more sensitive. Using this method, specific antibodies present in polyclonal...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1985-09-01 00:00:00
abstract::S100P belongs to several members of the S100 family of calcium-binding proteins, associated with malignant phenotype. Altered levels of S100P expression have been described at different stages and types of cancer. Transcriptional regulation involves different pathways activated by glucocorticoids, growth factors and b...
journal_title:Acta virologica
pub_type: 杂志文章,评审
doi:10.4149/av_2013_02_238
更新日期:2013-01-01 00:00:00
abstract::An abortive infection was induced in L cells by influenza virus A/Hong Kong/68 (H3N2). With the use of antibody and peroxidase-labelled protein A, the localization of virus protein synthesis but not the maturation of virus particles was demonstrated at the ultrastructural level. Five days after inoculation (p.i.), the...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1981-11-01 00:00:00
abstract::Tick-borne encephalitis (TBE), a disease caused by tick-borne encephalitis virus (TBEV), represents a serious neural infection of humans in Europe and Asia. The main reservoir hosts of TBEV are ticks, rodents and insectivores, but domestic animals may also be infected with the virus. This review summarizes what is kno...
journal_title:Acta virologica
pub_type: 杂志文章
doi:10.4149/av_2020_212
更新日期:2020-01-01 00:00:00
abstract::Cauliflower mosaic virus (CaMV) - a plant pararetrovirus that naturally causes diseases in Brassicaceae and Solanaceae plant hosts worldwide - has been detected by PCR for the first time in herbarium samples of Usnea sp. lichens. The virus's presence in these lichens did not result in any micro- or macromorphological ...
journal_title:Acta virologica
pub_type: 杂志文章
doi:10.4149/av_2016_02_196
更新日期:2016-06-01 00:00:00
abstract::The densities of purified herpes simplex virus (HSV) particles prepared from infected rabbit lung (ZP) and baby hamster kidney (BHK-21) cells were investigated in potassium tartrate (PT) and potassium citrate (PC) density gradients. Virions obtained from ZP cells exhibited a higher density than those from BHK-21 cells...
journal_title:Acta virologica
pub_type: 杂志文章
doi:
更新日期:1976-12-01 00:00:00