Abstract：
:Spleen cells from mice infected with human adenovirus type 6 (Ad6) showed defective interleukin 2 (IL2) production 3-5 days after the infection. The response of spleen cells to exogenous IL 2 was also deficient. The impaired capacity of concanavalin A--(Con A)-activated spleen cells from Ad6--infected mice to utilize IL 2 seemed to be related to the depressed capacity of the infected splenocytes to express IL 2 receptors. The immunologic dysfunction following infection with Ad6 may be a consequence of deficiencies in both the elaboration of and response to IL 2.
journal_name
Acta Viroljournal_title
Acta virologicaauthors
Berencsi K,Bakay M,Béládi Isubject
Has Abstractpub_date
1991-08-01 00:00:00pages
350-6issue
4eissn
0001-723Xissn
1336-2305journal_volume
35pub_type
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