Nonlethal infection of laboratory mice induced with "mouse" rabies strains.

Abstract:

:Nonlethal infection was induced in laboratory mice with sublethal doses of rabies strains isolated from small wild rodents. Three types of nonlethal infecion were observed: persistent--with virus irregularly reisolable for at least 56 days after inoculation: latent--with negative virus reisolation but presence of infection demonstrable by transmission of virus neutralization activity to other animals; and abortive--with only a primary immune response, nontransmissible to other animals. A hyperreactive state called "early death" was observed in some mice. All surviving animals recovered without sequelae.

journal_name

Acta Virol

journal_title

Acta virologica

authors

Sodja I

subject

Has Abstract

pub_date

1980-09-01 00:00:00

pages

325-33

issue

5

eissn

0001-723X

issn

1336-2305

journal_volume

24

pub_type

杂志文章
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