Abstract:
:Osteoarthritis (OA), the most common type of arthritis worldwide, is a degenerative disease of diarthrodial joints resulting in pain, reduced quality of life, and socioeconomic burden. Gout, the most common form of inflammatory arthritis, is a consequence of persistently elevated levels of urate and the formation of proinflammatory monosodium urate crystals in joints. Clinicians have long noted a predilection for both diseases to occur in the same joints. In this review, we provide an overview into research elucidating possible biochemical, mechanical, and immunological relationships between gout and OA. We additionally consider the potential implications of these relationships for OA treatment.
journal_name
Curr Rheumatol Repjournal_title
Current rheumatology reportsauthors
Yokose C,Chen M,Berhanu A,Pillinger MH,Krasnokutsky Sdoi
10.1007/s11926-016-0613-9subject
Has Abstractpub_date
2016-10-01 00:00:00pages
65issue
10eissn
1523-3774issn
1534-6307pii
10.1007/s11926-016-0613-9journal_volume
18pub_type
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