Abstract:
PURPOSE OF THE REVIEW:Idiopathic acute and recurrent pericarditis are rare diseases of unknown origin. Here, we review trigger factors, pathomechanism, and treatment options for acute and recurrent pericarditis. RECENT FINDINGS:Acute pericarditis can be triggered by viral infections, myocardial ischemia, heart catheter interventions, cardiac surgery or seem to occur without any trigger. Earlier reports about viral nucleic acids in the effusion or myocardial autoantibodies in serum were detected only in a minority of patients. The current pathomechanistic concept focuses on the innate immune system. Clinical trials revealed that colchicine and anti-IL1β-targeted medication were effective to control acute and recurrent attacks. Activation of the innate immune system in pericarditis suggests that autoinflammation contributes to acute and recurrent pericarditis. The efficacy of colchicine and anti-IL1β-targeted medication in clinical trials indicates that acute and recurrent pericarditis should be regarded as an autoinflammatory disease. Therefore, idiopathic pericarditis should be considered as an autoinflammatory disease.
journal_name
Curr Rheumatol Repjournal_title
Current rheumatology reportsauthors
Blank N,Lorenz HMdoi
10.1007/s11926-019-0820-2subject
Has Abstractpub_date
2019-03-09 00:00:00pages
18issue
5eissn
1523-3774issn
1534-6307pii
10.1007/s11926-019-0820-2journal_volume
21pub_type
杂志文章,评审abstract::Bone is not structurally normal in osteoarthritis (OA). Periarticular bone in OA has increased turnover, decreased bone mineral content and stiffness, and decreased trabecular numbers. The increased turnover of collagen, in particular, may affect the biomechanical competence of bone and is driven by a number of proces...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-003-0078-5
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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abstract::Sleep disturbance is one of the most common comorbid problems for chronic pain patients. The association between the two phenomena has long been recognized, but the nature of the relationship is not well-understood. Many agree that the relationship is likely bidirectional. In this review, we focus on one side of the r...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-011-0204-8
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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更新日期:2017-11-09 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-012-0311-1
更新日期:2013-03-01 00:00:00
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journal_title:Current rheumatology reports
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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更新日期:2016-08-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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更新日期:2009-07-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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更新日期:2018-05-12 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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更新日期:2015-02-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-996-0044-0
更新日期:2005-06-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-008-0007-8
更新日期:2008-01-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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更新日期:2011-02-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-018-0745-1
更新日期:2018-05-03 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-010-0114-1
更新日期:2010-08-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-015-0512-5
更新日期:2015-06-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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更新日期:2017-04-01 00:00:00
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journal_title:Current rheumatology reports
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pub_type: 杂志文章,评审
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journal_title:Current rheumatology reports
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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journal_title:Current rheumatology reports
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更新日期:2008-12-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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更新日期:2012-12-01 00:00:00
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
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