Abstract：
:β2-glycoprotein I (β2GPI) is the major autoantigen in the antiphospholipid syndrome. The central importance of understanding β2GPI physiology from the perspective of the rheumatologist is that it forms the foundation for understanding the pathophysiology underlying autoantibody generation, and the diverse mechanisms by which anti-β2GPI antibodies in complex with β2GPI may predispose an individual to the antiphospholipid syndrome clinical phenotype. This review examines some of the latest novel findings in this area.
journal_name
Curr Rheumatol Repjournal_title
Current rheumatology reportsauthors
Giannakopoulos B,Mirarabshahi P,Krilis SAdoi
10.1007/s11926-010-0151-9subject
Has Abstractpub_date
2011-02-01 00:00:00pages
90-5issue
1eissn
1523-3774issn
1534-6307journal_volume
13pub_type
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