Evidence for metabolic abnormalities in the muscles of patients with fibromyalgia.

abstract：:The magnitude of placebo analgesia is influenced by environmental and perceptual factors. Environmental factors include past exposure to effective analgesic agents and verbal suggestions and cues that foster a perception of being given an effective treatment. Environmental factors, in turn, influence the proximate psy...

journal_title：Current rheumatology reports

authors： Price DD,Fillingim RB,Robinson ME

更新日期：2006-12-01 00:00:00

abstract：:Clinical evaluation of patients with low bone mass attempts to determine which patients should be offered one of the effective therapies for fracture prevention. Current guidelines are primarily based on bone density. Risk factors are used, but their contribution to fracture risk is not easily assessed. The combinatio...

journal_title：Current rheumatology reports

authors： Deal CL

更新日期：2007-04-01 00:00:00

abstract：:The prevalence of gout appears to be rapidly increasing worldwide and is no longer a disorder suffered primarily by over-fed alcohol consumers. Emerging risk factors include longevity, metabolic syndrome, and new classes of pharmacologic agents. In some ethnic populations, no obvious risk factors can explain the high ...

journal_title：Current rheumatology reports

authors： Zaka R,Williams CJ

更新日期：2006-06-01 00:00:00

abstract：:Antiphospholipid syndrome is an important cause of neurologic morbidity. The clinical criteria for antiphospholipid syndrome include only cerebrovascular arterial and venous thrombosis, but many other neurologic manifestations have been associated with antiphospholipid antibodies (aPL). This review discusses the role ...

journal_title：Current rheumatology reports

authors： Roldan JF,Brey RL

更新日期：2007-05-01 00:00:00

abstract：:Psoriatic arthritis is a chronic inflammatory joint disease, seen in combination with the chronic inflammatory skin disease psoriasis and belonging to the family of spondylarthritides (SpA). A link is recognized between psoriatic arthritis and inflammatory bowel disease (IBD). Environmental factors seem to induce infl...

journal_title：Current rheumatology reports

authors： Eppinga H,Konstantinov SR,Peppelenbosch MP,Thio HB

更新日期：2014-03-01 00:00:00

abstract：:Large epidemiologic studies of gout can improve insight into the etiology, pathology, impact, and management of the disease. Identification of monosodium urate monohydrate crystals is considered the gold standard for diagnosis, but its application is often not possible in large studies. Therefore, under such circumsta...

journal_title：Current rheumatology reports

authors： Wijnands JM,Boonen A,Arts IC,Dagnelie PC,Stehouwer CD,van der Linden S

更新日期：2011-04-01 00:00:00

abstract：:Management of the pregnant patient with antiphospholipid antibody (aPL) is reviewed, with emphasis on recent randomized controlled clinical trials. These support the use of subcutaneous heparin and low dose aspirin, current standard therapy for women with aPL and a history of fetal loss. Prednisone is rarely used due ...

journal_title：Current rheumatology reports

authors： Sammaritano LR

更新日期：2001-06-01 00:00:00

abstract：:Osteoarthritis (OA) is a major health problem in urgent need of better treatment. Gene therapy offers to meet this need. Of the different strategies for using gene therapy in OA, local gene transfer to synovium is in the most advanced stage of development. Local gene transfer brings several advantages, including a foc...

journal_title：Current rheumatology reports

authors： Evans CH

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Chikungunya virus (CHIKV) infection has become increasingly prevalent in the last decade not only across the southern hemisphere but also, because of a recently documented viral mutation, in southern Europe and the USA. With the global spread of CHIKV infection, practitioners should know its epidemiol...

journal_title：Current rheumatology reports

authors： Hua C,Combe B

更新日期：2017-10-05 00:00:00

abstract：:Erosive osteoarthritis (OA) is a subcategory of OA in which destructive changes occur in the joints, probably as a result of a combination of inflammatory inciters and phenomena. The major changes occur in the distal and proximal interphalangeal joints, root joints of the thumb, and less commonly other hand and centri...

journal_title：Current rheumatology reports

authors： Ehrlich GE

更新日期：2001-12-01 00:00:00

abstract：:Juvenile idiopathic arthritis (JIA) is in a majority of the cases of self-limiting, and sometimes even a self-remitting, disease. A growing amount of data suggests that active T cell regulation determines, at least partly, the clinical outcome of JIA. In experimental models of arthritis, a group of highly conserved mi...

journal_title：Current rheumatology reports

authors： Prakken B,Kuis W,van Eden W,Albani S

更新日期：2002-12-01 00:00:00

abstract：:Uric acid nephrolithiasis is typically found in individuals with a low urine pH and a normal concentration of urinary uric acid. Patients with a history of gout are at greater risk of forming uric acid stones, as are patients with obesity, diabetes, or the complete metabolic syndrome. The unifying renal tubular abnorm...

journal_title：Current rheumatology reports

authors： Liebman SE,Taylor JG,Bushinsky DA

更新日期：2007-06-01 00:00:00

abstract：:The high-range estimate of 1.3% by the National Arthritis Data Workgroup for the prevalence of the entire spectrum of spondyloarthropathies (SpAs) suggests that SpAs may be more prevalent than rheumatoid arthritis (RA) in the United States. Recent surveys from many European countries using the same sample population h...

journal_title：Current rheumatology reports

authors： Akkoc N

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Osteoarthritis (OA) is the most common form of arthritis and a major source of pain and disability worldwide. OA-associated pain is usually refractory to classically used analgesics, and disease-modifying therapies are still lacking. Therefore, a better understanding of mechanisms and mediators contri...

journal_title：Current rheumatology reports

authors： Syx D,Tran PB,Miller RE,Malfait AM

更新日期：2018-02-26 00:00:00

abstract：:Sjögren's syndrome is a chronic inflammatory process involving primarily the exocrine glands. Its association with lymphoma is well documented. A low-grade marginal-zone lymphoma related to mucosa-associated lymphoid tissue is the most common lymphoid neoplasia in Sjögren's syndrome. Among all autoimmune diseases, Sjö...

journal_title：Current rheumatology reports

authors： Voulgarelis M,Moutsopoulos HM

更新日期：2003-08-01 00:00:00

abstract：:Gout is the most common inflammatory arthropathy and occurs in the setting of elevated serum urate levels. Gout is also known to be associated with multiple comorbidities including cardiovascular disease and the metabolic syndrome. Recent advances in research have increased our understanding and improved our knowledge...

journal_title：Current rheumatology reports

authors： George RL,Keenan RT

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Ankylosing spondylitis (AS) was historically seen as a predominantly male disease. However, more recent data showed a more homogenous sex prevalence. Unfortunately, in many studies in axial spondyloarthritis (axSpA), the number of women included is low and the analyses are often not stratified for gen...

journal_title：Current rheumatology reports

authors： Rusman T,van Vollenhoven RF,van der Horst-Bruinsma IE

更新日期：2018-05-12 00:00:00

abstract：:Vasculitis is defined as inflammation of blood vessels and can affect multiple organs. Several classification systems exist to categorize vasculitis such as vessel size, presence of anti-neutrophil cytoplasmic antibody, pathogenesis of the inflammation, and type of inflammatory cell infiltrate. Cutaneous vasculitis oc...

journal_title：Current rheumatology reports

authors： Hayat S,Berney SM

更新日期：2005-08-01 00:00:00

abstract：:Transforming growth factor-beta (TGF beta) plays a critical role in the development of tissue fibrosis. Its expression is consistently elevated in affected organs and correlates with increased extracellular matrix deposition. During the last few years, tremendous progress has been made in understanding the molecular a...

journal_title：Current rheumatology reports

authors： Verrecchia F,Mauviel A

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF THE REVIEW:An increased prevalence of cardiovascular risk factors in rheumatoid arthritis (RA) is reported. The absolute cardiovascular risk in RA patients is higher than in the general population, and although the RA prognosis has gradually improved, premature cardiovascular (CV) mortality remains a matter ...

journal_title：Current rheumatology reports

authors： Romano S,Salustri E,Ruscitti P,Carubbi F,Penco M,Giacomelli R

更新日期：2018-11-05 00:00:00

abstract：:The human microbiome, which represents the total collection of microorganisms (and their genes) inhabiting the human body, has increasingly been recognized as a potential key factor in the development of autoimmune disease. Multiple studies suggest that the microbiome has significant influence on immune homeostasis, w...

journal_title：Current rheumatology reports

authors： Manasson J,Scher JU

更新日期：2015-02-01 00:00:00

abstract：:Gout and hyperuricemia have long been suspected to be risk factors for cardiovascular disease. However, studies have frequently failed to distinguish whether these entities have an independent effect on cardiovascular risk or serve as markers for other risk factors. In vitro and animal studies suggest that uric acid i...

journal_title：Current rheumatology reports

authors： Shah A,Keenan RT

更新日期：2010-04-01 00:00:00

abstract：:To date, most studies examining cell death during the development of osteoarthritis (OA) have focused on death of chondrocytes and have primarily examined advanced stages of the disease. Very good evidence suggests that chondrocyte death does occur at some point in the pathogenesis of OA and that it can be due to apop...

journal_title：Current rheumatology reports

authors： Del Carlo M Jr,Loeser RF

更新日期：2008-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a chronic debilitating condition with significant impact on the musculoskeletal system. Arthroplasty may be indicated for damage related to active lupus or its treatment. As therapies for SLE have advanced, morbidity and mortality have declined, while the rate of joint replacement...

journal_title：Current rheumatology reports

authors： Kasturi S,Goodman S

更新日期：2016-09-01 00:00:00

abstract：:Acute and chronic gout are common complications following organ transplantation. Risk factors include those shared with the general population (eg, diuretic use) and transplant-specific risk factors (eg, cyclosporine). Clinical features of gout are similar to those seen in the general population, although tophi may be...

journal_title：Current rheumatology reports

authors： Stamp LK,Chapman PT

更新日期：2012-04-01 00:00:00

abstract：:This study had two objectives: to describe the historical development of self-reported presenteeism instruments that can be used to identify and measure presenteeism as a result of musculoskeletal disease (MSD) and to identify if, and how many of these, presenteeism instruments are underpinned by economic theory. Syst...

journal_title：Current rheumatology reports

authors： Jones C,Payne K,Gannon B,Verstappen S

更新日期：2016-08-01 00:00:00

abstract：:Small-vessel vasculitis is a convenient descriptor for a wide range of diseases characterized by vascular inflammation of the venules, capillaries, and/or arterioles with pleomorphic clinical manifestations. The classical clinical phenotype is leukocytoclastic vasculitis with palpable purpura, but manifestations vary ...

journal_title：Current rheumatology reports

authors： Iglesias-Gamarra A,Restrepo JF,Matteson EL

更新日期：2007-08-01 00:00:00

abstract：:Optimal management for scleroderma (systemic sclerosis) is likely to require treatment of the underlying disease process, which remains incompletely understood, and also of the organ-based complications of this heterogeneous condition. Clinical trials evaluating several potential agents have been completed recently, i...

journal_title：Current rheumatology reports

authors： Denton CP,Black CM

更新日期：1999-10-01 00:00:00

abstract：:Seronegative spondyloarthropathies comprise a group of inflammatory arthritides, which consists of ankylosing spondylitis, psoriatic arthritis, reactive arthritis (Reiter's syndrome), enteropathic arthritis, and undifferentiated spondyloarthropathy. All of them share common laboratory, clinical, and imaging findings, ...

journal_title：Current rheumatology reports

authors： Grigoryan M,Roemer FW,Mohr A,Genant HK

更新日期：2004-04-01 00:00:00

abstract：:Osteoporosis and related fractures represent a major, and growing, public health concern for the United States and worldwide. The pathogenesis of osteoporosis is complex, requiring attention to the different life phases involved in growth, maintenance, and loss of bone, in addition to non-skeletal factors associated w...

journal_title：Current rheumatology reports

authors： Samelson EJ,Hannan MT

更新日期：2006-02-01 00:00:00