Abstract：
:Acute and chronic gout are common complications following organ transplantation. Risk factors include those shared with the general population (eg, diuretic use) and transplant-specific risk factors (eg, cyclosporine). Clinical features of gout are similar to those seen in the general population, although tophi may be more common. A definitive diagnosis requires demonstration of monosodium urate crystals within synovial fluid or tophi. Treatment is often empiric, although a poor response should prompt joint aspiration to exclude septic arthritis. Corticosteroids are commonly used to treat acute gout due to the adverse profile and drug interactions with NSAIDs and colchicine. Sustained reduction of serum urate (≤6 mg/dL) is critical in long-term management. Allopurinol is the most commonly used agent, although vigilant monitoring is required if combined with azathioprine. Other options include febuxostat and benzbromarone. The role of newer agents such as interleukin-1 inhibitors and uricases remains to be determined. General measures should include minimizing diuretic use.
journal_name
Curr Rheumatol Repjournal_title
Current rheumatology reportsauthors
Stamp LK,Chapman PTdoi
10.1007/s11926-012-0235-9subject
Has Abstractpub_date
2012-04-01 00:00:00pages
165-72issue
2eissn
1523-3774issn
1534-6307journal_volume
14pub_type
杂志文章,评审abstract：:Sleep disturbance is one of the most common comorbid problems for chronic pain patients. The association between the two phenomena has long been recognized, but the nature of the relationship is not well-understood. Many agree that the relationship is likely bidirectional. In this review, we focus on one side of the r...
journal_title：Current rheumatology reports
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journal_title：Current rheumatology reports
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更新日期：2018-03-08 00:00:00
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journal_title：Current rheumatology reports
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更新日期：2017-09-01 00:00:00
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journal_title：Current rheumatology reports
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journal_title：Current rheumatology reports
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更新日期：2002-06-01 00:00:00
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更新日期：2000-04-01 00:00:00
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journal_title：Current rheumatology reports
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更新日期：2008-10-01 00:00:00
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journal_title：Current rheumatology reports
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更新日期：1999-10-01 00:00:00
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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更新日期：2020-05-13 00:00:00
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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journal_title：Current rheumatology reports
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更新日期：2010-02-01 00:00:00
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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更新日期：2007-06-01 00:00:00
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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更新日期：2005-08-01 00:00:00
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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更新日期：2009-10-01 00:00:00
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journal_title：Current rheumatology reports
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journal_title：Current rheumatology reports
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journal_title：Current rheumatology reports
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更新日期：1999-12-01 00:00:00
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journal_title：Current rheumatology reports
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更新日期：2014-01-01 00:00:00
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journal_title：Current rheumatology reports
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更新日期：2006-06-01 00:00:00
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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更新日期：2007-05-01 00:00:00
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journal_title：Current rheumatology reports
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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更新日期：2005-10-01 00:00:00
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journal_title：Current rheumatology reports
pub_type： 杂志文章,评审
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