Exercise in inflammatory myopathies, including inclusion body myositis.

abstract：:Juvenile idiopathic arthritis (JIA) is in a majority of the cases of self-limiting, and sometimes even a self-remitting, disease. A growing amount of data suggests that active T cell regulation determines, at least partly, the clinical outcome of JIA. In experimental models of arthritis, a group of highly conserved mi...

journal_title：Current rheumatology reports

authors： Prakken B,Kuis W,van Eden W,Albani S

更新日期：2002-12-01 00:00:00

abstract：:While the most obvious manifestations of rheumatoid arthritis (RA) involve inflammation and damage in the synovial joints, the systemic effects of the condition are widespread and life-threatening. Of particular interest is the 'lipid paradox' of RA, where patients with a numerically equivocal starting lipid profile h...

journal_title：Current rheumatology reports

authors： McGrath CM,Young SP

更新日期：2015-09-01 00:00:00

abstract：:Genetic defects of collagen formation (the collagenopathies) affect almost every organ system and tissue in the body. They can be grouped by clinical phenotype, which usually correlates with the tissue distribution of the affected collagen subtype. Many of these conditions present in childhood; however, milder phenoty...

journal_title：Current rheumatology reports

authors： Jobling R,D'Souza R,Baker N,Lara-Corrales I,Mendoza-Londono R,Dupuis L,Savarirayan R,Ala-Kokko L,Kannu P

更新日期：2014-01-01 00:00:00

abstract：:Advanced imaging has become essential for recognition of clinically suspected early spondyloarthritis. This report summarizes recent progress towards a data-driven comprehensive definition of a positive sacroiliac joint MRI in axial spondyloarthritis, which incorporates contextual information provided by structural le...

journal_title：Current rheumatology reports

authors： Weber U,Jurik AG,Lambert RG,Maksymowych WP

更新日期：2016-09-01 00:00:00

abstract：:Gout is the most common inflammatory arthropathy and occurs in the setting of elevated serum urate levels. Gout is also known to be associated with multiple comorbidities including cardiovascular disease and the metabolic syndrome. Recent advances in research have increased our understanding and improved our knowledge...

journal_title：Current rheumatology reports

authors： George RL,Keenan RT

更新日期：2013-02-01 00:00:00

abstract：:Erosive osteoarthritis (OA) is a subcategory of OA in which destructive changes occur in the joints, probably as a result of a combination of inflammatory inciters and phenomena. The major changes occur in the distal and proximal interphalangeal joints, root joints of the thumb, and less commonly other hand and centri...

journal_title：Current rheumatology reports

authors： Ehrlich GE

更新日期：2001-12-01 00:00:00

abstract：:Although exercise in the form of stretching, strength maintenance, and aerobic conditioning is generally considered beneficial to patients with fibromyalgia (FM), there is no reliable evidence to explain why exercise should help alleviate the primary symptom of FM, namely pain. Study results are varied and do not prov...

journal_title：Current rheumatology reports

authors： Clark SR,Jones KD,Burckhardt CS,Bennett R

更新日期：2001-04-01 00:00:00

abstract：:Osteoporosis is a potentially preventable condition frequently encountered in patients with systemic lupus erythematosus (SLE). Bone loss in SLE is likely a multi- factorial process involving traditional osteoporosis risk factors along with lupus-related factors. Recognizing potential contributors to bone loss in pati...

journal_title：Current rheumatology reports

authors： Lee C,Ramsey-Goldman R

更新日期：2005-12-01 00:00:00

abstract：:Silicone-gel breast implant rupture is common. Silicone-gel from ruptured implants may escape the scar capsule that forms around breast implants and become "extracapsular silicone." Our previously published study found that women with extracapsular silicone gel were at higher risk of reporting that they were diagnosed...

journal_title：Current rheumatology reports

authors： Brown SL,Duggirala HJ,Pennello G

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Idiopathic acute and recurrent pericarditis are rare diseases of unknown origin. Here, we review trigger factors, pathomechanism, and treatment options for acute and recurrent pericarditis. RECENT FINDINGS:Acute pericarditis can be triggered by viral infections, myocardial ischemia, heart cathete...

journal_title：Current rheumatology reports

authors： Blank N,Lorenz HM

更新日期：2019-03-09 00:00:00

abstract：:The magnitude of placebo analgesia is influenced by environmental and perceptual factors. Environmental factors include past exposure to effective analgesic agents and verbal suggestions and cues that foster a perception of being given an effective treatment. Environmental factors, in turn, influence the proximate psy...

journal_title：Current rheumatology reports

authors： Price DD,Fillingim RB,Robinson ME

更新日期：2006-12-01 00:00:00

abstract：:Optimal management for scleroderma (systemic sclerosis) is likely to require treatment of the underlying disease process, which remains incompletely understood, and also of the organ-based complications of this heterogeneous condition. Clinical trials evaluating several potential agents have been completed recently, i...

journal_title：Current rheumatology reports

authors： Denton CP,Black CM

更新日期：1999-10-01 00:00:00

abstract：:Recent clinical development programs for new therapeutic agents in rheumatoid arthritis have included assessment of radiographic progression comparing changes with treatment to placebo and active controls. Studies now use reliable methods of assessment and sufficient study length to detect radiographic changes. Althou...

journal_title：Current rheumatology reports

authors： Wolfe F,Strand V

更新日期：2001-02-01 00:00:00

abstract：:Behçet's syndrome is a systemic vasculitis with an unknown etiology affecting the small and large vessels of the venous and arterial systems. At least two clusters of disease expression have been described. The first includes superficial vein thrombosis, deep vein thrombosis, and dural sinus thrombi. The second includ...

journal_title：Current rheumatology reports

authors： Yazici Y,Yurdakul S,Yazici H

更新日期：2010-12-01 00:00:00

abstract：:Clinical evaluation of patients with low bone mass attempts to determine which patients should be offered one of the effective therapies for fracture prevention. Current guidelines are primarily based on bone density. Risk factors are used, but their contribution to fracture risk is not easily assessed. The combinatio...

journal_title：Current rheumatology reports

authors： Deal CL

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The effect of urate lowering treatment (ULT) on cardiovascular (CV) risk and mortality in gout has been a topic of interest. This review discusses the CV effect of ULT and comparative CV safety among ULT agents. RECENT FINDINGS:The mechanism linking gout with CV risk is not fully understood but seems...

journal_title：Current rheumatology reports

authors： Kang EH,Kim SC

更新日期：2019-07-24 00:00:00

abstract：:Rheumatoid arthritis is a chronic inflammatory disease that results in generalized bone loss and increased fracture risk. Characteristic radiologic features of rheumatoid arthritis include periarticular osteopenia and marginal erosions. An emerging literature highlights the importance of osteoclasts as mediators of th...

journal_title：Current rheumatology reports

authors： Deal C

更新日期：2012-06-01 00:00:00

abstract：:Inflammatory joint diseases such as rheumatoid arthritis, as well as other rheumatic conditions, such as systemic lupus erythematosus (SLE) and ankylosing spondylitis, comprise a heterogeneous group of joint disorders that are all associated with extra-articular side effects, including bone loss and fractures. The con...

journal_title：Current rheumatology reports

authors： Bultink IE,Vis M,van der Horst-Bruinsma IE,Lems WF

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF THE REVIEW:An increased prevalence of cardiovascular risk factors in rheumatoid arthritis (RA) is reported. The absolute cardiovascular risk in RA patients is higher than in the general population, and although the RA prognosis has gradually improved, premature cardiovascular (CV) mortality remains a matter ...

journal_title：Current rheumatology reports

authors： Romano S,Salustri E,Ruscitti P,Carubbi F,Penco M,Giacomelli R

更新日期：2018-11-05 00:00:00

abstract：:Dendritic cells are professional antigen-presenting cells that are most studied for their function in mediating T-cell tolerance and T-cell activation. In addition, recent evidence indicates that dendritic cells can regulate the vasculature and function of fibroblast-type cells. The potential contribution of dendritic...

journal_title：Current rheumatology reports

authors： Lu TT

更新日期：2012-02-01 00:00:00

abstract：:Many lines of evidence suggest that autoimmune diseases result from chronic immune activation following environmental exposures in genetically susceptible individuals. A genetic basis for autoimmunity is supported by twin and family studies, candidate gene investigations, animal models, and whole genome microsatellite...

journal_title：Current rheumatology reports

authors： Shamim EA,Miller FW

更新日期：2000-06-01 00:00:00

abstract：:Traditional nonsteroidal anti-inflammatory drugs block cyclooxygenase (COX). They are the most widely used drugs for pain relief. They are indispensable for their effects but are condemned for their adverse drug reactions. Two COX inhibitors, acetaminophen and aspirin, are the most widely used over-the-counter drugs. ...

journal_title：Current rheumatology reports

authors： Brune K,Hinz B,Otterness I

更新日期：2009-02-01 00:00:00

abstract：:Atypical femur fractures are rare but a growing concern, as they are more common in patients who use bisphosphonates. The best radiology-based studies have had access to only short-term exposure data, while the studies using prescription databases with substantial long-term data did not have access to radiology report...

journal_title：Current rheumatology reports

authors： Abrahamsen B,Clark EM

更新日期：2012-06-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is associated with a heightened risk of cardiovascular disease (CVD) events, presumably related to a greater burden of atherosclerosis, as well as atherosclerotic plaques that tend to be inflamed and rupture prone. Many of the inflammatory pathways underlying the pathobiology of RA are also r...

journal_title：Current rheumatology reports

authors： Giles JT

更新日期：2016-05-01 00:00:00

abstract：:Widespread muscle pain, fatigue, and weakness are defining characteristics of patients with fibromyalgia (FM). The aim of this review is to summarize recent investigations of muscle abnormalities in FM, which can be classified as structural, metabolic, or functional in nature. Histologic muscle abnormalities of membra...

journal_title：Current rheumatology reports

authors： Park JH,Niermann KJ,Olsen N

更新日期：2000-04-01 00:00:00

abstract：:Systemic vasculitis can affect practically any structure in or around the eye. Although the ocular presentations of vasculitic disease are highly variable and may be quite subtle, it is important for physicians to understand some of the basic concepts, critical findings, and potential significance of ocular signs and ...

journal_title：Current rheumatology reports

authors： Shepherd JB 3rd

更新日期：2003-04-01 00:00:00

abstract：:The classification of Spondyloarthritis (SpA) has been revised with the introduction of the ASAS classification criteria. Although this has best been described in ankylosing spondylitis and psoriatic arthritis, there are population studies evaluating the epidemiology of the different subgroups of SpA. In this paper, w...

journal_title：Current rheumatology reports

authors： Bakland G,Nossent HC

更新日期：2013-09-01 00:00:00

abstract：:Vasculitis is defined as inflammation of blood vessels and can affect multiple organs. Several classification systems exist to categorize vasculitis such as vessel size, presence of anti-neutrophil cytoplasmic antibody, pathogenesis of the inflammation, and type of inflammatory cell infiltrate. Cutaneous vasculitis oc...

journal_title：Current rheumatology reports

authors： Hayat S,Berney SM

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The concept of cellular senescence has been evolving. Although originally proposed based on studies of serum-driven replication of cell lines in vitro, it is now clear that cellular senescence occurs in vivo. It has also become clear that cellular senescence can be triggered by a number of stimuli suc...

journal_title：Current rheumatology reports

authors： Gao L,Slack M,Barnas JL,McDavid A,Anolik J,Looney RJ

更新日期：2019-01-14 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study was to highlight recent findings on evaluation for lung transplantation and outcomes after transplantation in patients with systemic sclerosis (scleroderma). RECENT FINDINGS:The recognition that extra-pulmonary disease manifestations can seriously compromise post-transplant ...

journal_title：Current rheumatology reports

authors： Shah RJ,Boin F

更新日期：2017-05-01 00:00:00