Epidemiology of the rheumatic diseases of childhood.

abstract：:Gout is the most common inflammatory arthropathy and occurs in the setting of elevated serum urate levels. Gout is also known to be associated with multiple comorbidities including cardiovascular disease and the metabolic syndrome. Recent advances in research have increased our understanding and improved our knowledge...

journal_title：Current rheumatology reports

authors： George RL,Keenan RT

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF THE REVIEW:An increased prevalence of cardiovascular risk factors in rheumatoid arthritis (RA) is reported. The absolute cardiovascular risk in RA patients is higher than in the general population, and although the RA prognosis has gradually improved, premature cardiovascular (CV) mortality remains a matter ...

journal_title：Current rheumatology reports

authors： Romano S,Salustri E,Ruscitti P,Carubbi F,Penco M,Giacomelli R

更新日期：2018-11-05 00:00:00

abstract：:Large epidemiologic studies of gout can improve insight into the etiology, pathology, impact, and management of the disease. Identification of monosodium urate monohydrate crystals is considered the gold standard for diagnosis, but its application is often not possible in large studies. Therefore, under such circumsta...

journal_title：Current rheumatology reports

authors： Wijnands JM,Boonen A,Arts IC,Dagnelie PC,Stehouwer CD,van der Linden S

更新日期：2011-04-01 00:00:00

abstract：:The pediatric rheumatologist cares for children who may have a wide variety of causes of musculoskeletal pain. These include such diverse conditions as arthritis, low-back pain, hypermobility, metabolic bone pain, and amplified pain syndromes such as complex regional pain syndrome and fibromyalgia. This review examine...

journal_title：Current rheumatology reports

authors： Sherry DD

更新日期：2000-08-01 00:00:00

abstract：:Ayurvedic medicine is the traditional medicine of India, which originated over 5,000 years ago. Parts of this alternative medical system have become increasingly popular worldwide as patients seek approaches to medical care that they perceive as more holistic and less toxic than those offered by conventional Western m...

journal_title：Current rheumatology reports

authors： Basnyat S,Kolasinski SL

更新日期：2014-08-01 00:00:00

abstract：:The World Health Organization criteria for classification of bone mineral density (BMD) cannot be applied to premenopausal women because the relationship between BMD and fracture risk is not the same as in postmenopausal women. Approximately 2.5% of premenopausal women have BMD that is more than 2.0 standard deviation...

journal_title：Current rheumatology reports

authors： Lewiecki EM

更新日期：2005-03-01 00:00:00

abstract：:Interest in imaging ankylosing spondylitis (AS) and related spondyloarthropathies has increased in recent years. MRI is regarded as the most sensitive imaging modality to detect early inflammatory lesions in the sacroiliac joints and in the spine. Standard radiography plays a major role in evaluating potential disease...

journal_title：Current rheumatology reports

authors： Weber U,Kissling RO,Hodler J

更新日期：2007-10-01 00:00:00

abstract：:While the link between malignancy and vasculitis has been known for some time, the association of vasculitis and myelodysplastic syndrome (MDS) has only recently been reported. This article reviews the most current and landmark publications regarding MDS, as well as malignancy-associated vasculitis. We include theorie...

journal_title：Current rheumatology reports

authors： Agha A,Bateman H,Sterrett A,Valeriano-Marcet J

更新日期：2012-12-01 00:00:00

abstract：:The recent increase in the number of patients taking opioids chronically for pain has not yielded the expected benefits in reduction of symptoms and improved function. Chronic pain patients typically respond well initially to opioid medications, but regular use is associated with adverse psychological and physical eff...

journal_title：Current rheumatology reports

authors： Krashin D,Sullivan M,Ballantyne J

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The myofibroblast is the culprit in the pathogenesis of fibrosis in systemic sclerosis (SSc). Activation of morphogen signaling pathways has been shown to be critically involved in organ fibrosis. Remarkably, the cellular receptors and key molecules from these signaling pathways are localized in the p...

journal_title：Current rheumatology reports

authors： Teves ME,Strauss JF 3rd,Sapao P,Shi B,Varga J

更新日期：2019-05-21 00:00:00

abstract：:Antiphospholipid antibodies are associated with a hypercoagulable state leading to a wide variety of systemic manifestations and obstetric complications. The different pathologic manifestations can be a result of arterial and venous thrombosis, microthrombotic angiopathy, embolization, obstetric disease, and non-throm...

journal_title：Current rheumatology reports

authors： DeMarco P,Singh I,Weinstein A

更新日期：2006-04-01 00:00:00

abstract：:The inflammatory myopathies are a heterogeneous group of diseases including dermatomyositis, polymyositis, and inclusion body myositis. Few clinical trials have been conducted in myositis, making it difficult to provide clear recommendations on the treatment of these rare disorders. Although corticosteroids have not b...

journal_title：Current rheumatology reports

authors： Aggarwal R,Oddis CV

更新日期：2011-06-01 00:00:00

abstract：:Neonatal lupus is a disease characterized by one or more of the following findings: congenital heart block, cardiomyopathy, cutaneous lupus lesions, hepatobiliary disease, and thrombocytopenia. Accumulating evidence indicates that the disease is probably caused by maternal autoantibodies, particularly autoantibodies o...

journal_title：Current rheumatology reports

authors： Lee LA

更新日期：2001-10-01 00:00:00

abstract：:Although the pathogenesis of SLE remains poorly understood, there is consensus that it involves a combination of genetic, hormonal, and environmental factors. New technologies applied to genomic and gene expression studies have revealed novel gene mutations and cytokine alterations in this disease. Recently, advances ...

journal_title：Current rheumatology reports

authors： Stichweh D,Pascual V

更新日期：2005-12-01 00:00:00

abstract：:Skin fibrosis occurs in a variety of human diseases, most notably systemic sclerosis (SSc). The end stage of scleroderma in human skin consists of excess collagen deposition in the dermis with loss of adnexal structures and associated adipose tissue. The initiating factors for this process and the early stages are bel...

journal_title：Current rheumatology reports

authors： Smith GP,Chan ES

更新日期：2010-02-01 00:00:00

abstract：:There is a wide variation in the prevalence, incidence, and clinical manifestation of psoriatic arthritis (PsA) across countries due to genetic and environmental factors. Data on PsA in Asia are limited and come from small cross-sectional studies. The burden of PsA in Asia is high, including poor physical functioning,...

journal_title：Current rheumatology reports

authors： Leung YY,Tam LS,Li EK

更新日期：2011-08-01 00:00:00

abstract：:Osteoporosis is a potentially preventable condition frequently encountered in patients with systemic lupus erythematosus (SLE). Bone loss in SLE is likely a multi- factorial process involving traditional osteoporosis risk factors along with lupus-related factors. Recognizing potential contributors to bone loss in pati...

journal_title：Current rheumatology reports

authors： Lee C,Ramsey-Goldman R

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Pain is an intense experience that can place a heavy burden on peoples' lives. The identification of psychosocial risk factors led to the development of effective pain treatments. However, effect sizes are modest. Accumulating evidence suggests that enhancing protective factors might also impact on (w...

journal_title：Current rheumatology reports

authors： Hanssen MM,Peters ML,Boselie JJ,Meulders A

更新日期：2017-11-09 00:00:00

abstract：PURPOSE OF REVIEW:Osteoarthritis (OA) is the most common form of arthritis and a major source of pain and disability worldwide. OA-associated pain is usually refractory to classically used analgesics, and disease-modifying therapies are still lacking. Therefore, a better understanding of mechanisms and mediators contri...

journal_title：Current rheumatology reports

authors： Syx D,Tran PB,Miller RE,Malfait AM

更新日期：2018-02-26 00:00:00

abstract：:Hereditary hemochromatosis is a frequent disease in Caucasian populations. It leads to progressive iron overload in a variety of organs. The most common cause is the C282Y homozygous mutation in the HFE gene. The classical triad of skin hyperpigmentation, diabetes, and liver cirrhosis is nowadays rare but musculoskele...

journal_title：Current rheumatology reports

authors： Husar-Memmer E,Stadlmayr A,Datz C,Zwerina J

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Idiopathic acute and recurrent pericarditis are rare diseases of unknown origin. Here, we review trigger factors, pathomechanism, and treatment options for acute and recurrent pericarditis. RECENT FINDINGS:Acute pericarditis can be triggered by viral infections, myocardial ischemia, heart cathete...

journal_title：Current rheumatology reports

authors： Blank N,Lorenz HM

更新日期：2019-03-09 00:00:00

abstract：:Health outcomes and their measures used as end points in systemic lupus erythematosus (SLE) patient care and clinical trials have been varied and are still evolving. Although significant reductions in morbidity and mortality in SLE have been achieved, the medications approved for SLE have remained the same during the ...

journal_title：Current rheumatology reports

authors： Jolly M

更新日期：2010-08-01 00:00:00

abstract：:Clinical evaluation of patients with low bone mass attempts to determine which patients should be offered one of the effective therapies for fracture prevention. Current guidelines are primarily based on bone density. Risk factors are used, but their contribution to fracture risk is not easily assessed. The combinatio...

journal_title：Current rheumatology reports

authors： Deal CL

更新日期：2007-04-01 00:00:00

abstract：:Silicone-gel breast implant rupture is common. Silicone-gel from ruptured implants may escape the scar capsule that forms around breast implants and become "extracapsular silicone." Our previously published study found that women with extracapsular silicone gel were at higher risk of reporting that they were diagnosed...

journal_title：Current rheumatology reports

authors： Brown SL,Duggirala HJ,Pennello G

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study was to highlight recent findings on evaluation for lung transplantation and outcomes after transplantation in patients with systemic sclerosis (scleroderma). RECENT FINDINGS:The recognition that extra-pulmonary disease manifestations can seriously compromise post-transplant ...

journal_title：Current rheumatology reports

authors： Shah RJ,Boin F

更新日期：2017-05-01 00:00:00

abstract：:To date, most studies examining cell death during the development of osteoarthritis (OA) have focused on death of chondrocytes and have primarily examined advanced stages of the disease. Very good evidence suggests that chondrocyte death does occur at some point in the pathogenesis of OA and that it can be due to apop...

journal_title：Current rheumatology reports

authors： Del Carlo M Jr,Loeser RF

更新日期：2008-01-01 00:00:00

abstract：:Our growing understanding of the immune response mechanism has created a wave of novel biologic agents for the treatment of rheumatoid arthritis. The domain of biologic agents includes: 1) Recombinant regulatory cytokines; 2) engineered molecules and monoclonal antibodies that target proinflammatory cytokines; 3) mono...

journal_title：Current rheumatology reports

authors： Bulpitt KJ

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF THE REVIEW:We will address current treatment and unmet needs in psoriatic arthritis (PsA), examine existing randomized controlled trials (RCTs), and consider options for new trial designs and challenges in their implementation. RECENT FINDINGS:While therapeutic options for PsA have rapidly increased, there ...

journal_title：Current rheumatology reports

authors： Ogdie A,Coates L

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:One justification for using expensive biologic therapy in rheumatoid arthritis (RA) has been that it can reduce future healthcare utilization such as joint surgeries and physician visits. However, the evidence to support this assertion is unclear. We conducted a review of the literature for studies wh...

journal_title：Current rheumatology reports

authors： Bansback N,Fu E,Sun H,Guh D,Zhang W,Lacaille D,Milbers K,Anis AH

更新日期：2017-09-01 00:00:00

abstract：:The classification of Spondyloarthritis (SpA) has been revised with the introduction of the ASAS classification criteria. Although this has best been described in ankylosing spondylitis and psoriatic arthritis, there are population studies evaluating the epidemiology of the different subgroups of SpA. In this paper, w...

journal_title：Current rheumatology reports

authors： Bakland G,Nossent HC

更新日期：2013-09-01 00:00:00