Abstract:
:Neonatal lupus is a disease characterized by one or more of the following findings: congenital heart block, cardiomyopathy, cutaneous lupus lesions, hepatobiliary disease, and thrombocytopenia. Accumulating evidence indicates that the disease is probably caused by maternal autoantibodies, particularly autoantibodies of the Ro family. While often initially asymptomatic, mothers tend to develop symptoms of connective tissue disease. This review discusses the recent advances in the understanding of neonatal lupus, its clinical features, therapy, and pathogenesis.
journal_name
Curr Rheumatol Repjournal_title
Current rheumatology reportsauthors
Lee LAdoi
10.1007/s11926-996-0009-3keywords:
subject
Has Abstractpub_date
2001-10-01 00:00:00pages
391-5issue
5eissn
1523-3774issn
1534-6307journal_volume
3pub_type
杂志文章,评审abstract::There have been few studies examining whether persons with chronic widespread pain or fibromyalgia are at increased risk for dying prematurely. Among the studies conducted there is little consistency in results. If there is an increased mortality risk, it is of the order of a 30% excess and it may be related to the li...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-005-0017-8
更新日期:2005-10-01 00:00:00
abstract::Wegener's granulomatosis (WG) is a complex autoimmune disorder that has been transformed from a uniformly lethal process to a chronic disease with a relapsing-remitting course. In the setting of frequent relapses, the need to manage cumulative disease damage and drug toxicities has spurred the identification and devel...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-006-0014-6
更新日期:2006-08-01 00:00:00
abstract::Advanced imaging has become essential for recognition of clinically suspected early spondyloarthritis. This report summarizes recent progress towards a data-driven comprehensive definition of a positive sacroiliac joint MRI in axial spondyloarthritis, which incorporates contextual information provided by structural le...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-016-0607-7
更新日期:2016-09-01 00:00:00
abstract::The recent increase in the number of patients taking opioids chronically for pain has not yielded the expected benefits in reduction of symptoms and improved function. Chronic pain patients typically respond well initially to opioid medications, but regular use is associated with adverse psychological and physical eff...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-012-0311-1
更新日期:2013-03-01 00:00:00
abstract::Spondyloarthritis (SpA) is a group of inflammatory rheumatic diseases whose main clinical feature is inflammation of the axial spine. Articular, periarticular, and extra-articular manifestations can also occur, depending on the type of spondyloarthritis. The most common clinical subsets of SpA are ankylosing spondylit...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-013-0347-x
更新日期:2013-08-01 00:00:00
abstract::Uric acid nephrolithiasis is typically found in individuals with a low urine pH and a normal concentration of urinary uric acid. Patients with a history of gout are at greater risk of forming uric acid stones, as are patients with obesity, diabetes, or the complete metabolic syndrome. The unifying renal tubular abnorm...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-007-0040-z
更新日期:2007-06-01 00:00:00
abstract::The classification of Spondyloarthritis (SpA) has been revised with the introduction of the ASAS classification criteria. Although this has best been described in ankylosing spondylitis and psoriatic arthritis, there are population studies evaluating the epidemiology of the different subgroups of SpA. In this paper, w...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-013-0351-1
更新日期:2013-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Ankylosing spondylitis (AS) was historically seen as a predominantly male disease. However, more recent data showed a more homogenous sex prevalence. Unfortunately, in many studies in axial spondyloarthritis (axSpA), the number of women included is low and the analyses are often not stratified for gen...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-018-0744-2
更新日期:2018-05-12 00:00:00
abstract::Ayurvedic medicine is the traditional medicine of India, which originated over 5,000 years ago. Parts of this alternative medical system have become increasingly popular worldwide as patients seek approaches to medical care that they perceive as more holistic and less toxic than those offered by conventional Western m...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-014-0435-6
更新日期:2014-08-01 00:00:00
abstract::The frequency of Takayasu's arteritis (TA) has been estimated to be 2.9 cases per 1 million people, with a female preponderance, although female-to-male ratio varies from different geographic areas. A high frequency of haplotype A24-B52-DR2 has been found in Japanese patients, without this association in other populat...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-002-0021-1
更新日期:2002-02-01 00:00:00
abstract::Hypocomplementemic urticarial vasculitis syndrome (HUVS) is an uncommon immune complex-mediated entity characterized by urticaria with persistent acquired hypocomplementemia. First described in 1973, HUVS is associated with several systemic findings including leukocytoclastic vasculitis, severe angioedema, laryngeal e...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-009-0060-y
更新日期:2009-12-01 00:00:00
abstract::Large epidemiologic studies of gout can improve insight into the etiology, pathology, impact, and management of the disease. Identification of monosodium urate monohydrate crystals is considered the gold standard for diagnosis, but its application is often not possible in large studies. Therefore, under such circumsta...
journal_title:Current rheumatology reports
pub_type: 杂志文章
doi:10.1007/s11926-010-0157-3
更新日期:2011-04-01 00:00:00
abstract::Small-vessel vasculitis is a convenient descriptor for a wide range of diseases characterized by vascular inflammation of the venules, capillaries, and/or arterioles with pleomorphic clinical manifestations. The classical clinical phenotype is leukocytoclastic vasculitis with palpable purpura, but manifestations vary ...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-007-0049-3
更新日期:2007-08-01 00:00:00
abstract::Psoriatic arthritis is a chronic inflammatory joint disease, seen in combination with the chronic inflammatory skin disease psoriasis and belonging to the family of spondylarthritides (SpA). A link is recognized between psoriatic arthritis and inflammatory bowel disease (IBD). Environmental factors seem to induce infl...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-013-0407-2
更新日期:2014-03-01 00:00:00
abstract::Apatite crystals form in physiologically calcified tissues, including the hyaline cartilage of the epiphyseal growth plate. While apatite crystals appear as unwanted deposits in other cartilage sites, more frequently, crystalline materials other than or in addition to apatite develop in dystrophic cartilage deposits. ...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-002-0072-3
更新日期:2002-06-01 00:00:00
abstract::Sjögren's syndrome is a chronic inflammatory process involving primarily the exocrine glands. Its association with lymphoma is well documented. A low-grade marginal-zone lymphoma related to mucosa-associated lymphoid tissue is the most common lymphoid neoplasia in Sjögren's syndrome. Among all autoimmune diseases, Sjö...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-003-0011-y
更新日期:2003-08-01 00:00:00
abstract:PURPOSE OF THE REVIEW:Osteoarthritis (OA) is an aging-associated and injury-induced joint disease characterized by cartilage degradation, bone sclerosis, and persistent low-grade inflammation in the joint. Aging and injury are triggers of joint pathological changes mediated by pro-inflammatory factors, some of which ar...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-019-0868-z
更新日期:2019-12-07 00:00:00
abstract::Urate is the major inert end product of purine degradation in higher primates in contrast to most other mammals because of the genetic silencing of hepatic oxidative enzyme uricase. The kidney plays a dominant role in urate elimination. The kidney excretes 70% of the daily urate production. Therefore, it is important ...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-996-0044-0
更新日期:2005-06-01 00:00:00
abstract::Atypical femur fractures are rare but a growing concern, as they are more common in patients who use bisphosphonates. The best radiology-based studies have had access to only short-term exposure data, while the studies using prescription databases with substantial long-term data did not have access to radiology report...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-012-0241-y
更新日期:2012-06-01 00:00:00
abstract::Upregulated adhesion molecule and cytokine expression on endothelial cells and infiltrating inflammatory cells occur in most vasculitis syndromes. These observations suggest that vasculitis is associated with pathologic activation of normal immune cell cytokine cascades. Abnormal expression of adhesion molecules and c...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-000-0040-8
更新日期:2000-10-01 00:00:00
abstract::Acute and chronic gout are common complications following organ transplantation. Risk factors include those shared with the general population (eg, diuretic use) and transplant-specific risk factors (eg, cyclosporine). Clinical features of gout are similar to those seen in the general population, although tophi may be...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-012-0235-9
更新日期:2012-04-01 00:00:00
abstract::Gout is the most common inflammatory arthropathy and occurs in the setting of elevated serum urate levels. Gout is also known to be associated with multiple comorbidities including cardiovascular disease and the metabolic syndrome. Recent advances in research have increased our understanding and improved our knowledge...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-012-0309-8
更新日期:2013-02-01 00:00:00
abstract::The risk of infection accompanies the benefits of surgery. Immunomodulatory chronic illnesses may increase the risk of surgical infections. Surgical patients with rheumatologic illness need close preoperative assessment regarding their infection risks (fixed and modifiable), which vary on the basis of the proposed pro...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-013-0379-2
更新日期:2013-12-01 00:00:00
abstract::Recent human genetic discoveries have increased our understanding of rheumatoid arthritis (RA) susceptibility. Genome-wide association studies have expanded the number of validated RA risk loci beyond HLA-DRB1 "shared epitope" alleles to include additional major histocompatibility complex (MHC) risk alleles and more t...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-009-0050-0
更新日期:2009-10-01 00:00:00
abstract::Behçet's syndrome is a systemic vasculitis with an unknown etiology affecting the small and large vessels of the venous and arterial systems. At least two clusters of disease expression have been described. The first includes superficial vein thrombosis, deep vein thrombosis, and dural sinus thrombi. The second includ...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-010-0132-z
更新日期:2010-12-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a chronic disease affecting the physical, social, and psychological well-being of patients. Different instruments have been developed to measure health-related quality of life, some of which are SLE-specific. Contributors to poor quality of life in patients with SLE include fatigu...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-010-0114-1
更新日期:2010-08-01 00:00:00
abstract::Synovitis is the characteristic feature of inflammatory joint disease. If synovitis is localized to interphalangeal joints, rheumatoid arthritis, psoriatic arthritis, and juvenile idiopathic arthritis are among the most common differential diagnoses. The absence of pain, tenderness, and limitation of function despite ...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-014-0442-7
更新日期:2014-01-01 00:00:00
abstract::Interest in imaging ankylosing spondylitis (AS) and related spondyloarthropathies has increased in recent years. MRI is regarded as the most sensitive imaging modality to detect early inflammatory lesions in the sacroiliac joints and in the spine. Standard radiography plays a major role in evaluating potential disease...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-007-0057-3
更新日期:2007-10-01 00:00:00
abstract::Exercise is an important part of treatment in patients with idiopathic inflammatory myopathies. Improved functioning, ability to perform activities of daily living, and health-related quality of life have been reported in adult polymyositis, dermatomyositis, and also recently inclusion body myositis following differen...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-012-0248-4
更新日期:2012-06-01 00:00:00
abstract::The pediatric rheumatologist cares for children who may have a wide variety of causes of musculoskeletal pain. These include such diverse conditions as arthritis, low-back pain, hypermobility, metabolic bone pain, and amplified pain syndromes such as complex regional pain syndrome and fibromyalgia. This review examine...
journal_title:Current rheumatology reports
pub_type: 杂志文章,评审
doi:10.1007/s11926-000-0072-0
更新日期:2000-08-01 00:00:00