Abstract：
PURPOSE OF REVIEW:This review describes the effects of psychological stress on the physiology of the entire vascular system, from individual cellular components to macrovascular and microvascular responses, and highlights the importance of the vascular system in the context of current limitations in cardiac imaging for evaluation of the cardiovascular response to mental stress. RECENT FINDINGS:The physiological responses that mediate vascular changes are based on evolutionary needs, but there is increasing evidence that the long-term consequences of psychological stress can precipitate the development and progression of cardiovascular disease (CVD). While there is an extensive body of literature describing localized physiological responses or overt cardiovascular manifestations, often framed within the organ-specific scope of cardiovascular imaging, there has not been a comprehensive description of the global vascular effects of psychological stress. Given the global nature of these processes, targeted cardiovascular imaging modalities may be insufficient. Here we approach the vascular response to mental stress systematically, describing the effects on the endothelium, vascular smooth muscle, and adventitia. We then address the mental stress effects on large vessels and the microvascular compartment, with a discussion of the role of microvascular resistance in the pathophysiology of mental stress-induced myocardial ischemia. Vascular responses to psychological stress involve complex physiological processes that are not fully characterized by routine cardiovascular imaging assessments. Future research incorporating standardized psychological assessments targeted toward vascular mechanisms of stress responses is required to guide the development of behavioral and therapeutic interventions.
journal_name
Curr Cardiol Repjournal_title
Current cardiology reportsauthors
Shah SM,Meadows JL,Burg MM,Pfau S,Soufer Rdoi
10.1007/s11886-020-01406-xsubject
Has Abstractpub_date
2020-10-09 00:00:00pages
156issue
12eissn
1523-3782issn
1534-3170pii
10.1007/s11886-020-01406-xjournal_volume
22pub_type
杂志文章,评审abstract：:Lifestyle modification is primary in cardiovascular (CV) disease prevention. A major contribution is the Mediterranean diet (MedDiet), defined by two of seven components. Italian investigators determined a significant decrease in peripheral arterial disease of 56 % for a high score. Multiple specific CV risk factors a...
journal_title：Current cardiology reports
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journal_title：Current cardiology reports
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journal_title：Current cardiology reports
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journal_title：Current cardiology reports
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更新日期：2017-08-11 00:00:00
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更新日期：2010-09-01 00:00:00
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更新日期：2018-07-26 00:00:00
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