Abstract：
PURPOSE OF REVIEW:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are commonly used anti-hypertensive medications in a number of clinical settings. They are often used interchangeably, but we pose the provocative question as to whether they should be. We review the literature to evaluate for any differences in efficacy between the two classes in order to determine if the greater side effects associated with angiotensin-converting enzyme inhibitors are offset by any advantageous effects on outcomes to warrant their use over angiotensin receptor blockers. RECENT FINDINGS:In many clinical scenarios, the data supports similar efficacy between ACE inhibitors and ARBs, while in a minority of others, there are murky signals from previous trials that suggest ACE inhibitors may be better. However, when reviewing the literature in its entirety, and taking into account recently published pooled analysis and head to head trials, it is reasonable to conclude that ACE inhibitors and ARBs have similar efficacy. This is in contrast to data on adverse effects, which consistently favors the use of ARBs. From the available data, it is reasonable to conclude that ACE inhibitors and ARBs have equal efficacy yet unequal adverse effects. It is in this context that we take the provocative stance that ACE inhibitors should not be used to treat hypertension.
journal_name
Curr Cardiol Repjournal_title
Current cardiology reportsauthors
Turner JM,Kodali Rdoi
10.1007/s11886-020-01352-8subject
Has Abstractpub_date
2020-07-09 00:00:00pages
95issue
9eissn
1523-3782issn
1534-3170pii
10.1007/s11886-020-01352-8journal_volume
22pub_type
杂志文章,评审abstract：PURPOSE OF REVIEW:Acute pulmonary embolism (PE) is a common condition associated with high morbidity and mortality. Prior studies have evaluated the role of systemic fibrinolysis and catheter-directed therapy (CDT) in the management of PE. In this review, we examine current data on risk stratification and the appropria...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-017-0864-8
更新日期：2017-06-01 00:00:00
abstract：:The appropriateness of coronary revascularization for various clinical scenarios has been reviewed formally by several specialty and subspecialty societies resulting in the formulation of scored appropriateness criteria. The goal of the appropriateness criteria is to guide physician decision-making and future research...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-013-0379-x
更新日期：2013-07-01 00:00:00
abstract：:Imaging with radionuclides has historically played an important role in detection of cardiovascular disease as well as in risk stratification and prognostication. With the growth of molecular biology have come new therapeutic interventions and the requirement for new diagnostic imaging approaches. Noninvasive targeted...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-005-0025-3
更新日期：2005-03-01 00:00:00
abstract：:Increasing barriers to medical device innovation in the United States including constrained financial resources and rising research costs require that physicians take on greater involvement in medical device development, evaluation, and regulatory processes. Such involvement requires that physicians understand basic a...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-014-0494-3
更新日期：2014-01-01 00:00:00
abstract：:The decline in the use of sodium channel blockers has led to an expanding use of b-blockers and complex class III agents such as sotalol and amiodarone for controlling cardiac arrhythmias. Success with these agents in the context of their side effects has spurred the development of compounds with simpler ion channel-b...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-001-0086-x
更新日期：2001-07-01 00:00:00
abstract：PURPOSE OF REVIEW:The aim of this report is to describe the main aspects of sex-related differences in non-ischemic dilated cardiomyopathies (DCM), focusing on chemotherapy-induced heart failure (HF) and investigating the possible therapeutic implications and clinical management applications in the era of personalized ...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-020-01377-z
更新日期：2020-08-08 00:00:00
abstract：PURPOSE OF REVIEW:The number of pregnancies complicated by valvular heart disease is increasing. This review describes the hemodynamic effects of clinically important valvular abnormalities during pregnancy and reviews current guideline-driven management strategies. RECENT FINDINGS:Valvular heart disease in women of c...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-017-0910-6
更新日期：2017-08-24 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-011-0242-x
更新日期：2012-04-01 00:00:00
abstract：PURPOSE OF REVIEW:Heart failure with preserved ejection fraction (HFpEF) is a relatively new disease entity used in medical terminology; however, both the number of patients and its clinical significance are growing. HFpEF used to be seen as a mild condition; however, the symptoms and quality of life of the patients ar...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-020-01349-3
更新日期：2020-07-09 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章
doi：10.1007/s11886-005-0054-y
更新日期：2005-07-01 00:00:00
abstract：:Patients with severe carotid and coronary disease-especially if they require coronary artery bypass grafting (CABG)-are at high risk of cardiac events and stroke. Carotid revascularization should be considered for patients with symptomatic carotid disease and bilateral severe asymptomatic carotid stenosis. In patients...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-012-0246-1
更新日期：2012-04-01 00:00:00
abstract：:Leukocytes play a critical role in both the initial steps of atherogenesis and the late events of plaque instability and thrombosis. Leukocyte-endothelial cell adhesion molecules (CAMs) modulate the interaction between circulating leukocytes and the vessel wall. Levels of soluble CAMs are increased in patients with dy...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-999-0031-y
更新日期：1999-09-01 00:00:00
abstract：PURPOSE OF THE REVIEW:Atrial fibrillation (AF) is the most frequent arrhythmia in the general population. This review aims to provide a comprehensive overview of the psychological aspects of AF, compiling evidence from epidemiological, clinical, and basic research sources. RECENT FINDINGS:Findings from large-scale pop...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-020-01396-w
更新日期：2020-09-10 00:00:00
abstract：:Although differences diminish with age, outcomes are overall worse for women compared to men who present with suspected acute coronary syndrome. The reasons for this discrepancy are multifactorial, including sex-related differences in atherosclerosis biology and fluid dynamics, as well as a premature conclusion by pro...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-016-0767-0
更新日期：2016-09-01 00:00:00
abstract：PURPOSE OF REVIEW:Interventional cardiology and in particular the field of renal denervation is subject to constant change. This review provides an up to date overview of renal denervation trials and an outlook on what to expect in the future. RECENT FINDINGS:After the sham-controlled SYMPLICITY HTN-3 trial dampened t...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-019-1164-2
更新日期：2019-07-05 00:00:00
abstract：PURPOSE OF REVIEW:The pathogenesis and progression of coronary artery disease (CAD) is now known to be largely driven by inflammation on top of the well-accepted role for the disequilibrium between cholesterol deposition and removal from the arterial wall. Recent clinical trials have supported the inflammatory hypothes...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-020-01439-2
更新日期：2021-01-06 00:00:00
abstract：PURPOSE OF REVIEW:The development of biventricular repair and conversion pathways for patients with borderline hypoplastic heart disease represents an area of recent inquiry and innovation. This review summarizes emerging techniques and novel treatment algorithms for borderline hypoplastic heart disease with a focus on...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-020-01363-5
更新日期：2020-08-08 00:00:00
abstract：:This review focuses on the use of bivalirudin as a replacement anticoagulant for heparin in patients undergoing percutaneous coronary intervention, or who are being treated for unstable angina pectoris, ST-elevation, or non-ST-elevation myocardial infarction. Potential advantages of bivalirudin include a lack of depen...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-001-0050-9
更新日期：2001-09-01 00:00:00
abstract：PURPOSE OF REVIEW:Acute pulmonary embolism is a major cause of morbidity and mortality in the USA and throughout the world. This review will summarize recent developments in short- and long-term mortality risk assessment after an acute pulmonary embolism. RECENT FINDINGS:Recent guidelines have emphasized risk stratifi...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-018-1084-6
更新日期：2018-10-11 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-009-0054-4
更新日期：2009-09-01 00:00:00
abstract：PURPOSE OF REVIEW:To review methodological and logistical aspects of CT myocardial perfusion, current clinical evidence and possible future directions, with specific focus on use in patients with coronary artery disease (CAD). RECENT FINDINGS:CT myocardial perfusion imaging may be performed as an add-on to standard co...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-017-0937-8
更新日期：2017-10-25 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-020-01419-6
更新日期：2020-10-10 00:00:00
abstract：:The risk of stroke associated with carotid artery stenosis can be reduced with carotid endarterectomy or carotid artery stenting in carefully selected patients. While surgery has been the traditional treatment there have been many trials comparing carotid endarterectomy with carotid artery stenting, and stenting has s...
journal_title：Current cardiology reports
pub_type： 杂志文章
doi：10.1007/s11886-012-0250-5
更新日期：2012-02-05 00:00:00
abstract：PURPOSE:This paper reviews the double-kiss crush (DK crush) technique in coronary artery bifurcation lesions. The technical aspects of the procedure and the clinical data supporting its use are summarized. RECENT FINDINGS:Randomized studies support the adoption of DK technique in complex bifurcation lesions for both l...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-018-1024-5
更新日期：2018-09-01 00:00:00
abstract：:Congestive heart failure increasingly contributes to the overall morbidity and mortality associated with cardiovascular disease. Although significant advances in therapies allow patients to feel better and have improved functional status and survival, not all patients respond equally to these therapies. Moreover, for ...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-009-0021-0
更新日期：2009-03-01 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-018-1028-1
更新日期：2018-08-09 00:00:00
abstract：:The excess risk of hypertension in black Americans continues to be a major health concern. Although there is considerable information regarding these disease trends, much of the major underpinnings of the etiology of hypertension remain unclear. The excess mortality in blacks due to heart disease, renal failure, and s...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-004-0048-1
更新日期：2004-11-01 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-003-0110-4
更新日期：2003-11-01 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/s11886-000-0038-x
更新日期：2000-11-01 00:00:00
abstract：:A natural extension of current imaging paradigms for diagnosing coronary artery disease may well be the integration of CT with myocardial perfusion single-photon CT (SPECT). Although there is a wealth of clinical information regarding the utility of SPECT, the value of CT in the cardiology arena has only recently been...
journal_title：Current cardiology reports
pub_type： 杂志文章,评审
doi：10.1007/BF02938339
更新日期：2007-04-01 00:00:00
