Abstract:
PURPOSE OF REVIEW:This article reviews the latest data on unprotected left main (ULM) percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery, with a focus on the NOBLE and EXCEL trials. RECENT FINDINGS:In EXCEL trial, the primary endpoint at 3 years was 15.4% in the PCI group and 14.7% in the CABG group (p = 0.02 for non-inferiority of PCI versus CABG). In NOBLE, the primary endpoint at 5 years was 28% and 18% for PCI and CABG, respectively (HR 1.51, CI 1.13-2.0, which did not meet the criteria for non-inferiority of PCI to CABG; p for superiority of CABG was 0.0044). Higher repeat revascularization and non-procedural myocardial infarction were noted in PCI group but there was no difference in all-cause or cardiac mortality between the two groups. A heart team approach with appropriate patient selection, careful assessment of LM lesions, and meticulous procedural technique makes PCI a valid alternative to CABG for ULM stenosis.
journal_name
Curr Cardiol Repjournal_title
Current cardiology reportsauthors
Taha Y,Patel RAG,Bagai J,Sachdeva R,Kumar G,Prasad A,Nathan S,Paul TKdoi
10.1007/s11886-019-1113-0subject
Has Abstractpub_date
2019-03-18 00:00:00pages
27issue
5eissn
1523-3782issn
1534-3170pii
10.1007/s11886-019-1113-0journal_volume
21pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:Results from cardiovascular (CV) outcome trials have revealed important insights into the CV safety and efficacy of glucose-lowering agents, including dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 receptor agonists (GLP-1RA). RECENT FINDINGS:Among patients with T2DM, DPP-4i h...
journal_title:Current cardiology reports
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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journal_title:Current cardiology reports
pub_type: 杂志文章
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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journal_title:Current cardiology reports
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2020-03-30 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2017-05-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2012-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2018-03-23 00:00:00
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更新日期:2016-06-01 00:00:00
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pub_type: 杂志文章,评审
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