Preparation and preservation of viable Akkermansia muciniphila cells for therapeutic interventions.

abstract：:There is growing interest in the use of probiotic lactic acid bacteria (LAB) for prevention of hypercholesterolaemia. This study assessed the cholesterol lowering ability of Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 in growth media. Both LAB yielded >98% (39.2 μg/ml) cholesterol lowering in growt...

journal_title：Beneficial microbes

authors： Lim FT,Lim SM,Ramasamy K

更新日期：2017-02-07 00:00:00

abstract：:Listeria monocytogenes is an opportunistic food-borne pathogen and is life-threatening to individuals with a weakened immune system. The aim of this study was to determine if Lactobacillus plantarum 423 and Enterococcus mundtii ST4SA could prevent colonisation of L. monocytogenes in the gastro-intestinal tract (GIT). ...

journal_title：Beneficial microbes

authors： van Zyl WF,Deane SM,Dicks LM

更新日期：2016-01-01 00:00:00

abstract：:The metabolic end products of the large bowel microbiota contribute significantly to human health. After weaning to solid foods, some of the most important of these are the short chain fatty acids (SCFA) produced by the fermentation of undigested dietary components and endogenous secretions. The main SCFA are acetate,...

journal_title：Beneficial microbes

authors： Bird AR,Conlon MA,Christophersen CT,Topping DL

更新日期：2010-11-01 00:00:00

abstract：:Dysbiosis may contribute to constipation and its symptoms, therefore probiotic administration could improve significantly gut health and functions. The aim of the study was to investigate the effects of a long-lasting administration of Lactobacillus reuteri DSM 17938 (LR DSM 17938) on symptoms and quality of life (QoL...

journal_title：Beneficial microbes

authors： Riezzo G,Orlando A,D'Attoma B,Linsalata M,Martulli M,Russo F

更新日期：2018-01-29 00:00:00

abstract：:We previously reported that dietary heat-killed Lactobacillus brevis SBC8803 affects sleep rhythms in mice. The present study evaluated the effect of consumption of heat-killed SBC8803 on sleep architecture in humans. A non-randomised, placebo-controlled, double blind, and crossover pilot study was conducted using vol...

journal_title：Beneficial microbes

authors： Nakakita Y,Tsuchimoto N,Takata Y,Nakamura T

更新日期：2016-09-01 00:00:00

abstract：:The aim of this study was to evaluate how konjac glucomannan hydrolysates (GMH) could support the healthy re-colonisation of vaginal microflora post infections. A total of 26 female patients (12 controls and 14 treatments) aged 18 to 25 suffering from vaginal infection were recruited for this study. Patients were assi...

journal_title：Beneficial microbes

authors： Tester R,Al-Ghazzewi F,Shen N,Chen Z,Chen F,Yang J,Zhang D,Tang M

更新日期：2012-03-01 00:00:00

abstract：:Nutritional intervention studies, like those with pre- and probiotics, are often hampered by low effect sizes, reducing the power to demonstrate potential efficacy. Here, we perform computer simulations of a hypothetical clinical trial using such an intervention in order to elucidate determining factors that can be in...

journal_title：Beneficial microbes

authors： Larsen OFA,Claassen E,Brummer RJ

更新日期：2020-10-12 00:00:00

abstract：:Invasion of the gut by pathogenic Salmonella leads to production of IL-8 that initiates inflammatory reactions to combat the bacterium. However, its persistent production causes tissue damage and interventions that suppress IL-8 production prevent tissue damage. We hypothesised that probiotics could mediate their bene...

journal_title：Beneficial microbes

authors： Malago JJ,Tooten PC,Koninkx JF

更新日期：2010-06-01 00:00:00

abstract：:The intestinal microbiota forms a complex ecosystem that is in close contact with its host and has an important impact on health. An increasing number of disorders are associated with disturbances in this ecosystem. Also patients suffering from irritable bowel syndrome (IBS) show an altered composition of their gut mi...

journal_title：Beneficial microbes

authors： König J,Brummer RJ

更新日期：2014-09-01 00:00:00

abstract：:Faecal microbiota transfer (FMT) consists of the infusion of donor faecal material into the intestine of a patient with the aim to restore a disturbed gut microbiota. In this study, it was investigated whether FMT has an effect on faecal microbial composition, its functional capacity, faecal metabolite profiles and th...

journal_title：Beneficial microbes

authors： Holster S,Repsilber D,Geng D,Hyötyläinen T,Salonen A,Lindqvist CM,Rajan SK,de Vos WM,Brummer RJ,König J

更新日期：2020-12-22 00:00:00

abstract：:The present study investigated some in vitro properties for probiotic use of four strains of bifidobacteria isolated from faeces of healthy children (Bifidobacterium longum 51A, Bifidobacterium breve 1101A, Bifidobacterium pseudolongum 1191A and Bifidobacterium bifidum 1622A). In vitro tests were carried out to compar...

journal_title：Beneficial microbes

authors： Souza TC,Silva AM,Drews JR,Gomes DA,Vinderola CG,Nicoli JR

更新日期：2013-06-01 00:00:00

abstract：:Clinical studies have shown that probiotics positively affect oral health by decreasing gum bleeding and/or reducing salivary counts of certain oral pathogens. Our aim was to investigate the inhibitory effect of six probiotic lactobacilli against opportunistic oral Candida species. Sugar utilisation by both lactobacil...

journal_title：Beneficial microbes

authors： Jiang Q,Stamatova I,Kari K,Meurman JH

更新日期：2015-01-01 00:00:00

abstract：:This study aimed to systematically evaluate safety of probiotics and synbiotics in immune compromised adults (≥18 years). Safety was analysed using the Common Terminology Clinical Adverse Events (CTCAE version 4.0) classification, thereby providing an update on previous reports using the most recent available clinical...

journal_title：Beneficial microbes

authors： Van den Nieuwboer M,Brummer RJ,Guarner F,Morelli L,Cabana M,Claasen E

更新日期：2015-03-01 00:00:00

abstract：:This study evaluated the effects of Bifidobacterium longum 51A on the intestinal mucosa and inflammatory response in experimental colitis. Colitis was induced by administration of 3.5% dextran sodium sulphate (DSS) solution for 7 days. Two periods of administration were performed: treatment (T) group, mice received Bi...

journal_title：Beneficial microbes

authors： Abrantes FA,Nascimento BB,Andrade MER,de Barros PAV,Cartelle CT,Martins FS,Nicoli JR,Arantes RME,Generoso SV,Fernandes SOA,Cardoso VN

更新日期：2020-02-19 00:00:00

abstract：:The oral administration of Enterococcus faecium EF1 to new-born suckling and weaning piglets along with their growth performances and intestinal microbiota was investigated in this study. Twenty-four new-born piglets were initially divided into 2 groups. The probiotics group received 2 ml of 10% sterilised skimmed mil...

journal_title：Beneficial microbes

authors： Wang YB,Du W,Fu AK,Zhang XP,Huang Y,Lee KH,Yu K,Li WF,Li YL

更新日期：2016-09-01 00:00:00

abstract：:Vaginal lactobacilli offer protection against microbiota imbalance and genitourinary tract infections. We compared vaginal lactobacilli in 50 Estonian women of child-bearing age applying culture-based methods, quantitative PCR and next-generation sequencing (NGS). The culture-based methods found three different lactob...

journal_title：Beneficial microbes

authors： Smidt I,Kiiker R,Oopkaup H,Lapp E,Rööp T,Truusalu K,Štšepetova J,Truu J,Mändar R

更新日期：2015-01-01 00:00:00

abstract：:Evidence suggests that the gut microbiota might play an important role in fibromyalgia syndrome (FMS) and chronic fatigue syndrome (CFS). Our goal is to systematically review the reported effect of probiotic treatments in patients diagnosed with FMS or CFS. A systematic review was carried out using 14 databases (PubMe...

journal_title：Beneficial microbes

authors： Roman P,Carrillo-Trabalón F,Sánchez-Labraca N,Cañadas F,Estévez AF,Cardona D

更新日期：2018-06-15 00:00:00

abstract：:Intestinal and human milk microbiota studies during infancy have shown variations according to geographical location, delivery mode, gestational age, and mother-related factors during pregnancy. In this study, we performed metagenomic mycobiota analyses of 44 transient and mature human milk among five different groups...

journal_title：Beneficial microbes

authors： Dinleyici M,Pérez-Brocal V,Arslanoglu S,Aydemir O,Ozumut SS,Tekin N,Vandenplas Y,Moya A,Dinleyici EC

更新日期：2020-03-27 00:00:00

abstract：:Ingestion of milks fermented by Lactobacillus strains showing probiotic properties is an important tool to maintain gastrointestinal health. In this study, Lactobacillus rhamnosus D1 and Lactobacillus plantarum B7, isolated from Brazilian artisanal cheese, were used as starters for the functional fermented milks to as...

journal_title：Beneficial microbes

authors： Acurcio LB,Sandes SHC,Bastos RW,Sant'anna FM,Pedroso SHSP,Reis DC,Nunes ÁC,Cassali GD,Souza MR,Nicoli JR

更新日期：2017-08-24 00:00:00

abstract：:In concern to the continuously rising global prevalence of obesity, diabetes and associated diseases, novel preventive and therapeutic approaches are urgently required. However, to explore and develop such innovative strategies, a meticulous comprehension of the biological basis of these diseases is extremely importan...

journal_title：Beneficial microbes

authors： Nagpal R,Kumar M,Yadav AK,Hemalatha R,Yadav H,Marotta F,Yamashiro Y

更新日期：2016-01-01 00:00:00

abstract：:During the last years, the application of probiotics in gynaecological clinical practice has gained increasing relevance regarding therapy and prevention. This trend has also provoked the need for having tailored pharmaceutical preparations containing powerful microbial strains with defined properties. For the develop...

journal_title：Beneficial microbes

authors： Domig KJ,Kiss H,Petricevic L,Viernstein H,Unger F,Kneifel W

更新日期：2014-09-01 00:00:00

abstract：:The mechanism of neurodegeneration in Parkinson's disease (PD) remains unknown but it has been hypothesised that the intestinal tract could be an initiating and contributing factor to the neurodegenerative processes. In PD patients as well as in animal models for PD, alpha-synuclein-positive enteric neurons in the col...

journal_title：Beneficial microbes

authors： Perez-Pardo P,Dodiya HB,Engen PA,Naqib A,Forsyth CB,Green SJ,Garssen J,Keshavarzian A,Kraneveld AD

更新日期：2018-09-18 00:00:00

abstract：:The gut intestinal tract harbours a complex microbiota. Disturbances in the microbiota composition have been associated with several immune dysfunctions such as inflammatory diseases. Specific strains of probiotics have shown to beneficially influence the composition and/or metabolic activity of the endogenous microbi...

journal_title：Beneficial microbes

authors： Benyacoub J,Bosco N,Blanchard C,Demont A,Philippe D,Castiel-Higounenc I,Guéniche A

更新日期：2014-06-01 00:00:00

abstract：:The effects of the probiotic, Propionibacterium jensenii 702 (PJ 702), supplementation on egg productivity, egg shell thickness, fatty acid profile of eggs, and body weight in early layer hens were investigated. Twenty eight twenty-week-old starter pullets were evenly divided into a treatment and a control group for a...

journal_title：Beneficial microbes

authors： Luo J,King S,Adams MC

更新日期：2010-03-01 00:00:00

abstract：:The use of native microorganisms with probiotic capacity is an alternative tool for the treatment and prevention of several diseases that affect animals, such as neonatal calf diarrhoea. The selection of probiotic strains within a collection is based on different in vitro and in vivo assays, which predict their potent...

journal_title：Beneficial microbes

authors： Fernández S,Fraga M,Silveyra E,Trombert AN,Rabaza A,Pla M,Zunino P

更新日期：2018-06-15 00:00:00

abstract：:The gut microbiota contributes to host energy metabolism, and altered gut microbiota has been associated with obesity-related metabolic disorders. We previously reported that a probiotic alone or together with a prebiotic controls body fat mass in healthy overweight or obese individuals in a randomised, double-blind, ...

journal_title：Beneficial microbes

authors： Hibberd AA,Yde CC,Ziegler ML,Honoré AH,Saarinen MT,Lahtinen S,Stahl B,Jensen HM,Stenman LK

更新日期：2019-03-13 00:00:00

abstract：:Bacteriocins are bacterially-produced antimicrobial peptides that have killing activity principally against other relatively closely-related bacteria. Some bacteriocins of the lactic acid bacteria (LAB) have for many years been extensively applied in food biopreservation. However, especially during the last decade, a ...

journal_title：Beneficial microbes

authors： Todorov SD,de Melo Franco BDG,Tagg JR

更新日期：2019-04-19 00:00:00

abstract：:Alterations of the gut microbiota and mucosal barrier are linked with metabolic diseases. Our aim was to investigate the potential benefit of the potential probiotic Bifidobacterium animalis ssp. lactis 420 in reducing high-fat diet-induced body weight gain and diabetes in mice. In the obesity model, C57Bl/6J mice wer...

journal_title：Beneficial microbes

authors： Stenman LK,Waget A,Garret C,Klopp P,Burcelin R,Lahtinen S

更新日期：2014-12-01 00:00:00

abstract：:Over the past decade it has become clear that probiotic and commensal interactions with mucosal dendritic cells in the lamina propria or epithelial cells lining the mucosa can modulate specific functions of the mucosal immune system. Innate pattern-recognition receptors such as TLRs, NLRs and CLRs play a crucial role ...

journal_title：Beneficial microbes

authors： Meijerink M,Wells JM

更新日期：2010-11-01 00:00:00

abstract：:Strain specific properties of probiotics in providing supportive health effects in the immune system and the gastrointestinal tract have been widely investigated in vivo and in vitro. However, the underlying responsible mechanism is poorly described. By unravelling the probiotic-induced responses in a complex network ...

journal_title：Beneficial microbes

authors： Giahi L,Aumueller E,Elmadfa I,Haslberger AG

更新日期：2012-06-01 00:00:00