Abstract:
:Bacteriocins are bacterially-produced antimicrobial peptides that have killing activity principally against other relatively closely-related bacteria. Some bacteriocins of the lactic acid bacteria (LAB) have for many years been extensively applied in food biopreservation. However, especially during the last decade, a number of reports have appeared about unanticipated extensions to the generally rather narrow anti-bacterial activity spectrum of some of the LAB bacteriocins and novel applications have been proposed for bacteriocins ranging from controlling the growth of an increasingly-heterogeneous variety of pathogens, including Gram-negative multidrug resistant bacteria, viruses, yeasts, and in particular, difficult to control Mycobacterium spp., to their potential application as anticancer agents. How best can we assess this now rapidly-accumulating stream of reports on potential future applications of bacteriocins? Where is the line between realistic, science-based proposals and highly-speculative fiction and what are the 'critical points' that might help us to draw this line? In this review, we have attempted to analyse a selection of the presently-available data concerning relatively 'unorthodox' (i.e. beyond food preservation) applications of bacteriocins, and, by utilising our set of 'critical points', we endeavour to identify essential or/and missing information that appear crucial for success of the proposed applications.
journal_name
Benef Microbesjournal_title
Beneficial microbesauthors
Todorov SD,de Melo Franco BDG,Tagg JRdoi
10.3920/BM2018.0126subject
Has Abstractpub_date
2019-04-19 00:00:00pages
315-328issue
3eissn
1876-2883issn
1876-2891journal_volume
10pub_type
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journal_title:Beneficial microbes
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journal_title:Beneficial microbes
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Beneficial microbes
pub_type: 杂志文章,评审
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更新日期:2010-11-01 00:00:00
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journal_title:Beneficial microbes
pub_type: 杂志文章
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journal_title:Beneficial microbes
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journal_title:Beneficial microbes
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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更新日期:2014-06-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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