Postbiotics: facts and open questions. A position paper on the need for a consensus definition.

abstract：:Over the past decade it has become clear that probiotic and commensal interactions with mucosal dendritic cells in the lamina propria or epithelial cells lining the mucosa can modulate specific functions of the mucosal immune system. Innate pattern-recognition receptors such as TLRs, NLRs and CLRs play a crucial role ...

journal_title：Beneficial microbes

authors： Meijerink M,Wells JM

更新日期：2010-11-01 00:00:00

abstract：:Bacterial vaginosis (BV) is characterised by a depletion of lactobacilli in favour of an overgrowth of anaerobic bacteria. It is associated with increased risk for urogenital infections and abortion. In this study we assessed the effect of a yoghurt drink containing Lactobacillus strains on BV. The strains had been is...

journal_title：Beneficial microbes

authors： Laue C,Papazova E,Liesegang A,Pannenbeckers A,Arendarski P,Linnerth B,Domig KJ,Kneifel W,Petricevic L,Schrezenmeir J

更新日期：2018-01-29 00:00:00

abstract：:Gut bacteria influence host anatomy and physiology. It has been proposed that bacterial metabolites including polyamines are responsible for intestinal maturation and mucosal growth. We have hypothesised that bacterially produced polyamines act as trophic factors and thereby influence large intestinal crypt depth and ...

journal_title：Beneficial microbes

authors： Slezak K,Hanske L,Loh G,Blaut M

更新日期：2013-09-01 00:00:00

abstract：:Ingestion of milks fermented by Lactobacillus strains showing probiotic properties is an important tool to maintain gastrointestinal health. In this study, Lactobacillus rhamnosus D1 and Lactobacillus plantarum B7, isolated from Brazilian artisanal cheese, were used as starters for the functional fermented milks to as...

journal_title：Beneficial microbes

authors： Acurcio LB,Sandes SHC,Bastos RW,Sant'anna FM,Pedroso SHSP,Reis DC,Nunes ÁC,Cassali GD,Souza MR,Nicoli JR

更新日期：2017-08-24 00:00:00

abstract：:Hypercholesterolemia is a main risk factor of cardiovascular disease. Probiotics are a safe approach to reduce elevated cholesterol without any deleterious effect to human health. Saccharomyces boulardii CNCM I-745 probiotic properties are well documented in a context of intestinal dysbiosis. Recent in vitro and precl...

journal_title：Beneficial microbes

authors： Briand F,Sulpice T,Giammarinaro P,Roux X

更新日期：2019-05-28 00:00:00

abstract：:Nutritional intervention studies, like those with pre- and probiotics, are often hampered by low effect sizes, reducing the power to demonstrate potential efficacy. Here, we perform computer simulations of a hypothetical clinical trial using such an intervention in order to elucidate determining factors that can be in...

journal_title：Beneficial microbes

authors： Larsen OFA,Claassen E,Brummer RJ

更新日期：2020-10-12 00:00:00

abstract：:The present work looks at the role of phytate-degrading Pediococcus pentosaceus CFR R123 application in functional foods to evaluate the fate of phytate and calcium solubility during fermentation. Under standard conditions, CFR R123 grown in modified MRS containing sodium phytate CFR R123 showed 43% degradation of sod...

journal_title：Beneficial microbes

authors： Raghavendra P,Ushakumari SR,Halami PM

更新日期：2011-03-01 00:00:00

abstract：:The gut intestinal tract harbours a complex microbiota. Disturbances in the microbiota composition have been associated with several immune dysfunctions such as inflammatory diseases. Specific strains of probiotics have shown to beneficially influence the composition and/or metabolic activity of the endogenous microbi...

journal_title：Beneficial microbes

authors： Benyacoub J,Bosco N,Blanchard C,Demont A,Philippe D,Castiel-Higounenc I,Guéniche A

更新日期：2014-06-01 00:00:00

abstract：:Knee osteoarthritis (OA) treatment is challenging due to inefficacy and adverse effects of current medications. Probiotic treatment has been shown to promote bone metabolism, reduce pain and inflammatory responses of age-related musculoskeletal disorders, including OA. We aimed to investigate the effect of probiotic L...

journal_title：Beneficial microbes

authors： Lei M,Guo C,Wang D,Zhang C,Hua L

更新日期：2017-10-13 00:00:00

abstract：:Dysbiosis may contribute to constipation and its symptoms, therefore probiotic administration could improve significantly gut health and functions. The aim of the study was to investigate the effects of a long-lasting administration of Lactobacillus reuteri DSM 17938 (LR DSM 17938) on symptoms and quality of life (QoL...

journal_title：Beneficial microbes

authors： Riezzo G,Orlando A,D'Attoma B,Linsalata M,Martulli M,Russo F

更新日期：2018-01-29 00:00:00

abstract：:The current leading view is that functionality and not phylotype is the most important determinant for the services provided by the gut microbiota. Here we present an alternative opinion, advocating the importance of phylotype in addition to function. We believe the literature is misled by technical artifacts in defin...

journal_title：Beneficial microbes

authors： Avershina E,Rudi K

更新日期：2013-09-01 00:00:00

abstract：:The gut is hypothesised to play an important role in the development and progression of sepsis. It is however unknown whether the gut microbiome and the gut barrier function is already altered early in sepsis development and whether it is possible to modulate the microbiome in early sepsis. Therefore, a randomised, do...

journal_title：Beneficial microbes

authors： Stadlbauer V,Horvath A,Komarova I,Schmerboeck B,Feldbacher N,Klymiuk I,Durdevic M,Rainer F,Blesl A,Stiegler P,Leber B

更新日期：2019-04-19 00:00:00

abstract：:In recent years, many authors have investigated the possible antidiabetic effect of lactic acid bacteria. Lactobacillus species constitute a major part of the lactic acid bacteria group and have been found to exhibit beneficial effects on the development of diabetes and its complications. In the current study, we inve...

journal_title：Beneficial microbes

authors： Yakovlieva M,Tacheva T,Mihaylova S,Tropcheva R,Trifonova K,Toleкova A,Danova S,Vlaykova T

更新日期：2015-01-01 00:00:00

abstract：:Intestinal and human milk microbiota studies during infancy have shown variations according to geographical location, delivery mode, gestational age, and mother-related factors during pregnancy. In this study, we performed metagenomic mycobiota analyses of 44 transient and mature human milk among five different groups...

journal_title：Beneficial microbes

authors： Dinleyici M,Pérez-Brocal V,Arslanoglu S,Aydemir O,Ozumut SS,Tekin N,Vandenplas Y,Moya A,Dinleyici EC

更新日期：2020-03-27 00:00:00

abstract：:The effects of the probiotic, Propionibacterium jensenii 702 (PJ 702), supplementation on egg productivity, egg shell thickness, fatty acid profile of eggs, and body weight in early layer hens were investigated. Twenty eight twenty-week-old starter pullets were evenly divided into a treatment and a control group for a...

journal_title：Beneficial microbes

authors： Luo J,King S,Adams MC

更新日期：2010-03-01 00:00:00

abstract：:The gut microbiota plays a crucial role in gastrointestinal health. Current use of probiotics is aimed at modulating the bacterial gut composition to alleviate specific diseases. The safety and tolerance of three probiotic strains (Bifidobacterium longum subsp. infantis R0033, Lactobacillus helveticus R0052 and Bifido...

journal_title：Beneficial microbes

authors： De Andrés J,Manzano S,García C,Rodríguez JM,Espinosa-Martos I,Jiménez E

更新日期：2018-06-15 00:00:00

abstract：:The establishment of the gut microbiota immediately after birth is a dynamic process that may impact lifelong health. At this important developmental stage in early life, human milk oligosaccharides (HMOs) serve as specific substrates to shape the gut microbiota of the nursling. The well-orchestrated transition is imp...

journal_title：Beneficial microbes

authors： Chia LW,Mank M,Blijenberg B,Bongers RS,van Limpt K,Wopereis H,Tims S,Stahl B,Belzer C,Knol J

更新日期：2020-11-16 00:00:00

abstract：:The human body is exposed to many xenobiotic, potentially harmful compounds. The intestinal immune system is crucial in protecting the human body from these substances. Moreover, many microorganisms, residing in the gastrointestinal tract, play an important role in modulating immune responses. Pre- and probiotics may ...

journal_title：Beneficial microbes

authors： Peters VBM,van de Steeg E,van Bilsen J,Meijerink M

更新日期：2019-04-19 00:00:00

abstract：:In concern to the continuously rising global prevalence of obesity, diabetes and associated diseases, novel preventive and therapeutic approaches are urgently required. However, to explore and develop such innovative strategies, a meticulous comprehension of the biological basis of these diseases is extremely importan...

journal_title：Beneficial microbes

authors： Nagpal R,Kumar M,Yadav AK,Hemalatha R,Yadav H,Marotta F,Yamashiro Y

更新日期：2016-01-01 00:00:00

abstract：:Invasion of the gut by pathogenic Salmonella leads to production of IL-8 that initiates inflammatory reactions to combat the bacterium. However, its persistent production causes tissue damage and interventions that suppress IL-8 production prevent tissue damage. We hypothesised that probiotics could mediate their bene...

journal_title：Beneficial microbes

authors： Malago JJ,Tooten PC,Koninkx JF

更新日期：2010-06-01 00:00:00

abstract：:During the last years, the application of probiotics in gynaecological clinical practice has gained increasing relevance regarding therapy and prevention. This trend has also provoked the need for having tailored pharmaceutical preparations containing powerful microbial strains with defined properties. For the develop...

journal_title：Beneficial microbes

authors： Domig KJ,Kiss H,Petricevic L,Viernstein H,Unger F,Kneifel W

更新日期：2014-09-01 00:00:00

abstract：:The gut microbiota contributes to host energy metabolism, and altered gut microbiota has been associated with obesity-related metabolic disorders. We previously reported that a probiotic alone or together with a prebiotic controls body fat mass in healthy overweight or obese individuals in a randomised, double-blind, ...

journal_title：Beneficial microbes

authors： Hibberd AA,Yde CC,Ziegler ML,Honoré AH,Saarinen MT,Lahtinen S,Stahl B,Jensen HM,Stenman LK

更新日期：2019-03-13 00:00:00

abstract：:Strain specific properties of probiotics in providing supportive health effects in the immune system and the gastrointestinal tract have been widely investigated in vivo and in vitro. However, the underlying responsible mechanism is poorly described. By unravelling the probiotic-induced responses in a complex network ...

journal_title：Beneficial microbes

authors： Giahi L,Aumueller E,Elmadfa I,Haslberger AG

更新日期：2012-06-01 00:00:00

abstract：:Faecal microbiota transfer (FMT) consists of the infusion of donor faecal material into the intestine of a patient with the aim to restore a disturbed gut microbiota. In this study, it was investigated whether FMT has an effect on faecal microbial composition, its functional capacity, faecal metabolite profiles and th...

journal_title：Beneficial microbes

authors： Holster S,Repsilber D,Geng D,Hyötyläinen T,Salonen A,Lindqvist CM,Rajan SK,de Vos WM,Brummer RJ,König J

更新日期：2020-12-22 00:00:00

abstract：:The probiotic strain Bifidobacterium bifidum YIT 10347 has been demonstrated to inhibit Helicobacter pylori activity, prevent injury to the gastric mucosa, and improve general gastric malaise symptoms in H. pylori positive patients. This study aimed to investigate the adhering activity and localisation of B. bifidum Y...

journal_title：Beneficial microbes

authors： Shibahara-Sone H,Gomi A,Iino T,Kano M,Nonaka C,Watanabe O,Miyazaki K,Ohkusa T

更新日期：2016-06-01 00:00:00

abstract：:The yoghurt bacteria, Streptococcus thermophilus and Lactobacillus delbrueckii ssp. bulgaricus, are alleged to have beneficial effects on human health. The objective of this study was to characterise growth, biochemical activity and competitive behaviour of these two bacteria in vitro and in vivo. S. thermophilus LMD-...

journal_title：Beneficial microbes

authors： Ben-Yahia L,Mayeur C,Rul F,Thomas M

更新日期：2012-09-01 00:00:00

abstract：:The anaerobic gut bacterium Akkermansia muciniphila is a well-characterised member of the mucosal microbiota and has shown to be a gut symbiont in human. A. muciniphila has been negatively associated with obesity and its associated metabolic disorders in various human cohorts while treatment with A. muciniphila cells ...

journal_title：Beneficial microbes

authors： Ouwerkerk JP,Aalvink S,Belzer C,De Vos WM

更新日期：2017-04-26 00:00:00

abstract：:A basic requirement for the prediction of the potential use of lactic acid bacteria (LAB) in the dairy industry is the identification of specific genes involved in flavour-forming pathways. The probiotic Lactobacillus delbrueckii UFV H2b20 was submitted to a genetic characterisation and phylogenetic analysis of genes ...

journal_title：Beneficial microbes

authors： Do Carmo AP,da Silva DF,De Oliveira MN,Borges AC,De Carvalho AF,De Moraes CA

更新日期：2011-09-01 00:00:00

abstract：:This study evaluated the effects of Bifidobacterium longum 51A on the intestinal mucosa and inflammatory response in experimental colitis. Colitis was induced by administration of 3.5% dextran sodium sulphate (DSS) solution for 7 days. Two periods of administration were performed: treatment (T) group, mice received Bi...

journal_title：Beneficial microbes

authors： Abrantes FA,Nascimento BB,Andrade MER,de Barros PAV,Cartelle CT,Martins FS,Nicoli JR,Arantes RME,Generoso SV,Fernandes SOA,Cardoso VN

更新日期：2020-02-19 00:00:00

abstract：:The use of native microorganisms with probiotic capacity is an alternative tool for the treatment and prevention of several diseases that affect animals, such as neonatal calf diarrhoea. The selection of probiotic strains within a collection is based on different in vitro and in vivo assays, which predict their potent...

journal_title：Beneficial microbes

authors： Fernández S,Fraga M,Silveyra E,Trombert AN,Rabaza A,Pla M,Zunino P

更新日期：2018-06-15 00:00:00